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Volumn 26, Issue 7, 2010, Pages 518-528

Pain management of musculoskeletal injuries in children: Current state and future directions

Author keywords

analgesia; fractures; nonpharmacological pain treatment; orthopedic injury; pain management; pharmacogenomics

Indexed keywords

CODEINE; CYTOCHROME P450 2D6; HYDROCODONE; IBUPROFEN; OXYCODONE; PARACETAMOL; NARCOTIC ANALGESIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT;

EID: 77954877671     PISSN: 07495161     EISSN: None     Source Type: Journal    
DOI: 10.1097/PEC.0b013e3181e5c02b     Document Type: Review
Times cited : (65)

References (79)
  • 1
    • 0036255527 scopus 로고    scopus 로고
    • The high prevalence of pain in emergency medical care
    • Cordell WH, Keene KK, Giles BK, et al. The high prevalence of pain in emergency medical care. Am J Emerg Med. 2002;20(3):165-169.
    • (2002) Am J Emerg Med , vol.20 , Issue.3 , pp. 165-169
    • Cordell, W.H.1    Keene, K.K.2    Giles, B.K.3
  • 2
    • 0033144651 scopus 로고    scopus 로고
    • A prospective study of ED pain management practices and the patient?s perspective
    • Tanabe P, Buschmann M. A prospective study of ED pain management practices and the patient?s perspective. J Emerg Nurs. 1999;25(3):171-177.
    • (1999) J Emerg Nurs , vol.25 , Issue.3 , pp. 171-177
    • Tanabe, P.1    Buschmann, M.2
  • 3
    • 20544478158 scopus 로고    scopus 로고
    • Pain in the emergency department with one-week follow-up of pain resolution
    • Johnston CC, Gagnon AJ, Pepler CJ, et al. Pain in the emergency department with one-week follow-up of pain resolution. Pain Res Manag. 2005;10(2):67-70.
    • (2005) Pain Res Manag , vol.10 , Issue.2 , pp. 67-70
    • Johnston, C.C.1    Gagnon, A.J.2    Pepler, C.J.3
  • 4
    • 1542377335 scopus 로고    scopus 로고
    • Emergency department management of pain and anxiety related to orthopedic fracture care: A guide to analgesic techniques and procedural sedation in children
    • Kennedy RM, Luhmann JD, Luhmann SJ. Emergency department management of pain and anxiety related to orthopedic fracture care: a guide to analgesic techniques and procedural sedation in children. Paediatr Drugs. 2004;6(1):11-31.
    • (2004) Paediatr Drugs , vol.6 , Issue.1 , pp. 11-31
    • Kennedy, R.M.1    Luhmann, J.D.2    Luhmann, S.J.3
  • 5
    • 1442301844 scopus 로고    scopus 로고
    • Patterns of injury in children: A population-based approach
    • Spady DW, Saunders DL, Schopflocher DP, et al. Patterns of injury in children: a population-based approach. Pediatrics. 2004;113(3 pt 1):522-529.
    • (2004) Pediatrics , vol.113 , Issue.3 PART. 1 , pp. 522-529
    • Spady, D.W.1    Saunders, D.L.2    Schopflocher, D.P.3
  • 6
    • 0030929284 scopus 로고    scopus 로고
    • Epidemiology of children's fractures
    • Landin LA. Epidemiology of children's fractures. J Pediatr Orthop B. 1997;6(2):79-83.
    • (1997) J Pediatr Orthop B , vol.6 , Issue.2 , pp. 79-83
    • Landin, L.A.1
  • 7
    • 34447324616 scopus 로고    scopus 로고
    • The epidemiology of fractures in children
    • Rennie L, Court-Brown CM, Mok JY, et al. The epidemiology of fractures in children. Injury. 2007;38(8):913-922.
    • (2007) Injury , vol.38 , Issue.8 , pp. 913-922
    • Rennie, L.1    Court-Brown, C.M.2    Mok, J.Y.3
  • 8
    • 21644455059 scopus 로고    scopus 로고
    • Epidemiology of childhood fractures in Britain: A study using the general practice research database
    • Cooper C, Dennison EM, Leufkens HG, et al. Epidemiology of childhood fractures in Britain: a study using the general practice research database. J Bone Miner Res. 2004;19(12):1976-1981.
    • (2004) J Bone Miner Res , vol.19 , Issue.12 , pp. 1976-1981
    • Cooper, C.1    Dennison, E.M.2    Leufkens, H.G.3
  • 9
    • 29944440011 scopus 로고    scopus 로고
    • Sedation and analgesia for pediatric fracture reduction in the emergency department: A systematic review
    • Migita RT, Klein EJ, Garrison MM. Sedation and analgesia for pediatric fracture reduction in the emergency department: a systematic review. Arch Pediatr Adolesc Med. 2006;160(1):46-51.
    • (2006) Arch Pediatr Adolesc Med , vol.160 , Issue.1 , pp. 46-51
    • Migita, R.T.1    Klein, E.J.2    Garrison, M.M.3
  • 10
    • 33947157197 scopus 로고    scopus 로고
    • The gap between pediatric emergency department procedural pain management treatments available and actual practice
    • MacLean S, Obispo J, Young KD. The gap between pediatric emergency department procedural pain management treatments available and actual practice. Pediatr Emerg Care. 2007;23(2):87-93
    • (2007) Pediatr Emerg Care , vol.23 , Issue.2 , pp. 87-93
    • MacLean, S.1    Obispo, J.2    Young, K.D.3
  • 11
    • 84923736164 scopus 로고    scopus 로고
    • The World Health Organization Accessed November 26
    • The World Health Organization. Available at: http://www.who.int/ mediacentre/news/notes/2007/np31/en/. Accessed November 26, 2009.
    • (2009)
  • 12
    • 0032107963 scopus 로고    scopus 로고
    • Children's responses to immunizations: Lullabies as a distraction
    • Megel ME, Houser CW, Gleaves LS. Children's responses to immunizations: lullabies as a distraction. Issues Compr Pediatr Nurs. 1998;21(3):129-145.
    • (1998) Issues Compr Pediatr Nurs , vol.21 , Issue.3 , pp. 129-145
    • Megel, M.E.1    Houser, C.W.2    Gleaves, L.S.3
  • 13
    • 0002048621 scopus 로고
    • Identifying coping strategies in children
    • Curry SL RS. Identifying coping strategies in children. J Clin Child Psych. 1985;14:61-68.
    • (1985) J Clin Child Psych , vol.14 , pp. 61-68
    • Curry Sl, R.S.1
  • 14
    • 0000815861 scopus 로고    scopus 로고
    • Childhood medical experience and temperament as predictors of adult functioning in medical situations
    • Pate JT, Blount RL, Cohen LL, et al. Childhood medical experience and temperament as predictors of adult functioning in medical situations. Child Health Care. 1996;25:281-298.
    • (1996) Child Health Care , vol.25 , pp. 281-298
    • Pate, J.T.1    Blount, R.L.2    Cohen, L.L.3
  • 15
    • 0031912163 scopus 로고    scopus 로고
    • Consequences of inadequate analgesia during painful procedures in children
    • Weisman SJ, Bernstein B, Schechter NL. Consequences of inadequate analgesia during painful procedures in children. Arch Pediatr Adolesc Med. 1998;152(2):147-149.
    • (1998) Arch Pediatr Adolesc Med , vol.152 , Issue.2 , pp. 147-149
    • Weisman, S.J.1    Bernstein, B.2    Schechter, N.L.3
  • 16
    • 0036514033 scopus 로고    scopus 로고
    • Use of analgesia in a paediatric accident and emergency department following limb trauma
    • O'Donnell J, Ferguson LP, Beattie TF. Use of analgesia in a paediatric accident and emergency department following limb trauma. Eur J Emerg Med. 2002;9(1):5-8.
    • (2002) Eur J Emerg Med , vol.9 , Issue.1 , pp. 5-8
    • Odonnell, J.1    Ferguson, L.P.2    Beattie, T.F.3
  • 17
    • 0042347752 scopus 로고    scopus 로고
    • Emergency department analgesia for fracture pain
    • Brown JC, Klein EJ, Lewis CW, et al. Emergency department analgesia for fracture pain. Ann Emerg Med. 2003;42(2):197-205.
    • (2003) Ann Emerg Med , vol.42 , Issue.2 , pp. 197-205
    • Brown, J.C.1    Klein, E.J.2    Lewis, C.W.3
  • 18
    • 1942487338 scopus 로고    scopus 로고
    • Practice patterns of pediatric versus general emergency physicians for pain management of fractures in pediatric patients
    • Cimpello LB, Khine H, Avner JR. Practice patterns of pediatric versus general emergency physicians for pain management of fractures in pediatric patients. Pediatr Emerg Care. 2004;20(4):228-232.
    • (2004) Pediatr Emerg Care , vol.20 , Issue.4 , pp. 228-232
    • Cimpello, L.B.1    Khine, H.2    Avner, J.R.3
  • 19
    • 0030969416 scopus 로고    scopus 로고
    • Pain management in the emergency department: Patterns of analgesic utilization
    • Petrack EM, Christopher NC, Kriwinsky J. Pain management in the emergency department: patterns of analgesic utilization. Pediatrics. 1997;99(5):711-714.
    • (1997) Pediatrics , vol.99 , Issue.5 , pp. 711-714
    • Petrack, E.M.1    Christopher, N.C.2    Kriwinsky, J.3
  • 20
    • 0030670111 scopus 로고    scopus 로고
    • Documented use of analgesics in the emergency department and upon release of patients with extremity fractures
    • Ngai B, Ducharme J. Documented use of analgesics in the emergency department and upon release of patients with extremity fractures. Acad Emerg Med. 1997;4(12):1176-1178.
    • (1997) Acad Emerg Med , vol.4 , Issue.12 , pp. 1176-1178
    • Ngai, B.1    Ducharme, J.2
  • 21
    • 0036012830 scopus 로고    scopus 로고
    • The effect of standard care, ibuprofen, and distraction on pain relief and patient satisfaction in children with musculoskeletal trauma
    • Tanabe P, Ferket K, Thomas R, et al. The effect of standard care, ibuprofen, and distraction on pain relief and patient satisfaction in children with musculoskeletal trauma. J Emerg Nurs. 2002;28(2):118-125.
    • (2002) J Emerg Nurs , vol.28 , Issue.2 , pp. 118-125
    • Tanabe, P.1    Ferket, K.2    Thomas, R.3
  • 22
    • 33845888260 scopus 로고    scopus 로고
    • Physician pain reminder as an intervention to enhance analgesia for extremity and clavicle injuries in pediatric emergency
    • Rogovik AL, Rostami M, Hussain S, et al. Physician pain reminder as an intervention to enhance analgesia for extremity and clavicle injuries in pediatric emergency. J Pain. 2007;8(1):26-32.
    • (2007) J Pain , vol.8 , Issue.1 , pp. 26-32
    • Rogovik, A.L.1    Rostami, M.2    Hussain, S.3
  • 24
    • 0028008772 scopus 로고
    • Emergency department analgesic use in pediatric trauma victims with fractures
    • Friedland LR, Kulick RM. Emergency department analgesic use in pediatric trauma victims with fractures. Ann Emerg Med. 1994;23(2):203-207.
    • (1994) Ann Emerg Med , vol.23 , Issue.2 , pp. 203-207
    • Friedland, L.R.1    Kulick, R.M.2
  • 25
    • 34249742083 scopus 로고    scopus 로고
    • Pain in the emergency department: Results of the Pain and Emergency Medicine Initiative (PEMI) multicenter study
    • Todd KH, Ducharme J, Choiniere M, et al. Pain in the emergency department: results of the Pain and Emergency Medicine Initiative (PEMI) multicenter study. J Pain. 2007;8(6):460-466.
    • (2007) J Pain , vol.8 , Issue.6 , pp. 460-466
    • Todd, K.H.1    Ducharme, J.2    Choiniere, M.3
  • 26
    • 33644845827 scopus 로고    scopus 로고
    • Outpatient pediatric pain management practices for fractures
    • Drendel AL, Lyon R, Bergholte J, et al. Outpatient pediatric pain management practices for fractures. Pediatr Emerg Care. 2006;22(2):94-99.
    • (2006) Pediatr Emerg Care , vol.22 , Issue.2 , pp. 94-99
    • Drendel, A.L.1    Lyon, R.2    Bergholte, J.3
  • 27
    • 39449108150 scopus 로고    scopus 로고
    • The squeaky wheel gets the grease: Parental pain management of children treated for bone fractures
    • Zisk RY, Grey M, Medoff-Cooper B, et al. The squeaky wheel gets the grease: parental pain management of children treated for bone fractures. Pediatr Emerg Care. 2008;24(2):89-96.
    • (2008) Pediatr Emerg Care , vol.24 , Issue.2 , pp. 89-96
    • Zisk, R.Y.1    Grey, M.2    Medoff-Cooper, B.3
  • 28
    • 34547608181 scopus 로고    scopus 로고
    • Current trends in the management of common painful conditions of preschool children in united states pediatric emergency departments
    • Khan AN, Sachdeva S. Current trends in the management of common painful conditions of preschool children in united states pediatric emergency departments. Clin Pediatr (Phila). 2007;46(7):626-631.
    • (2007) Clin Pediatr (Phila) , vol.46 , Issue.7 , pp. 626-631
    • Khan, A.N.1    Sachdeva, S.2
  • 29
    • 18344410750 scopus 로고    scopus 로고
    • Psychological therapies for the management of chronic and recurrent pain in children and adolescents
    • Eccleston C, Palermo TM, Williams ACdC, et al. Psychological therapies for the management of chronic and recurrent pain in children and adolescents. Cochrane Database Syst Rev. 2009;3:CD003968.
    • (2009) Cochrane Database Syst Rev , vol.3
    • Eccleston, C.1    Palermo, T.M.2    Acdc, W.3
  • 30
    • 0034809161 scopus 로고    scopus 로고
    • Managing acute pain and anxiety in children undergoing procedures in the emergency department
    • Krauss B. Managing acute pain and anxiety in children undergoing procedures in the emergency department. Emerg Med (Fremantle). 2001;13(3):293-304.
    • (2001) Emerg Med (Fremantle) , vol.13 , Issue.3 , pp. 293-304
    • Krauss, B.1
  • 31
    • 38849202353 scopus 로고    scopus 로고
    • The PRICE study (protection rest ice compression elevation): Design of a randomised controlled trial comparing standard versus cryokinetic ice applications in the management of acute ankle sprain [ISRCTN13903946]
    • Bleakley CM, O'Connor S, Tully MA, et al. The PRICE study (protection rest ice compression elevation): design of a randomised controlled trial comparing standard versus cryokinetic ice applications in the management of acute ankle sprain [ISRCTN13903946]. BMC Musculoskelet Disord. 2007;8:125.
    • (2007) BMC Musculoskelet Disord , vol.8 , pp. 125
    • Bleakley, C.M.1    Oconnor, S.2    Tully, M.A.3
  • 32
    • 33645024230 scopus 로고    scopus 로고
    • A randomized, controlled trial of removable splinting versus casting for wrist buckle fractures in children
    • Plint AC, Perry JJ, Correll R, et al. A randomized, controlled trial of removable splinting versus casting for wrist buckle fractures in children. Pediatrics. 2006;117(3):691-697.
    • (2006) Pediatrics , vol.117 , Issue.3 , pp. 691-697
    • Plint, A.C.1    Perry, J.J.2    Correll, R.3
  • 33
    • 68849104379 scopus 로고    scopus 로고
    • Backslab versus nonbackslab for immobilization of undisplaced supracondylar fractures: A randomized trial
    • Oakley E, Barnett P, Babl FE. Backslab versus nonbackslab for immobilization of undisplaced supracondylar fractures: a randomized trial. Pediatr Emerg Care. 2009;25(7):452-456.
    • (2009) Pediatr Emerg Care , vol.25 , Issue.7 , pp. 452-456
    • Oakley, E.1    Barnett, P.2    Babl, F.E.3
  • 34
    • 33746907797 scopus 로고    scopus 로고
    • Cryotherapy for acute ankle sprains: A randomised controlled study of two different icing protocols
    • discussion 705
    • Bleakley CM, McDonough SM, MacAuley DC, et al. Cryotherapy for acute ankle sprains: a randomised controlled study of two different icing protocols. Br J Sports Med. 2006;40(8):700-705; discussion 705.
    • (2006) Br J Sports Med , vol.40 , Issue.8 , pp. 700-705
    • Bleakley, C.M.1    McDonough, S.M.2    MacAuley, D.C.3
  • 35
    • 0032782140 scopus 로고    scopus 로고
    • Frostbite at the gym: A case report of an ice pack burn
    • O'Toole G, Rayatt S. Frostbite at the gym: a case report of an ice pack burn. Br J Sports Med. 1999;33(4):278-279.
    • (1999) Br J Sports Med , vol.33 , Issue.4 , pp. 278-279
    • Otoole, G.1    Rayatt, S.2
  • 36
    • 0942268954 scopus 로고    scopus 로고
    • The use of ice in the treatment of acute soft-tissue injury: A systematic review of randomized controlled trials
    • Bleakley C, McDonough S, MacAuley D. The use of ice in the treatment of acute soft-tissue injury: a systematic review of randomized controlled trials. Am J Sports Med. 2004;32(1):251-261.
    • (2004) Am J Sports Med , vol.32 , Issue.1 , pp. 251-261
    • Bleakley, C.1    McDonough, S.2    MacAuley, D.3
  • 37
    • 58149386284 scopus 로고    scopus 로고
    • Complementary and alternative medicine for acute procedural pain in children
    • Evans S, Tsao JC, Zeltzer LK. Complementary and alternative medicine for acute procedural pain in children. Altern Ther Health Med. 2008;14(5):52-56.
    • (2008) Altern Ther Health Med , vol.14 , Issue.5 , pp. 52-56
    • Evans, S.1    Tsao, J.C.2    Zeltzer, L.K.3
  • 38
    • 34247239866 scopus 로고    scopus 로고
    • Parental administration of analgesic medication in children after a limb injury
    • Maimon MS, Marques L, Goldman RD. Parental administration of analgesic medication in children after a limb injury. Pediatr Emerg Care. 2007;23(4):223-226.
    • (2007) Pediatr Emerg Care , vol.23 , Issue.4 , pp. 223-226
    • Maimon, M.S.1    Marques, L.2    Goldman, R.D.3
  • 39
    • 69549131021 scopus 로고    scopus 로고
    • Pain management practices in a pediatric emergency room (PAMPER) study: Interventions with nurses
    • Le May S, Johnston CC, Choiniere M, et al. Pain management practices in a pediatric emergency room (PAMPER) study: interventions with nurses. Pediatr Emerg Care. 2009;25(8):498-503.
    • (2009) Pediatr Emerg Care , vol.25 , Issue.8 , pp. 498-503
    • Le May, S.1    Johnston, C.C.2    Choiniere, M.3
  • 40
    • 33745127059 scopus 로고    scopus 로고
    • The therapeutic effects of music in children following cardiac surgery
    • Hatem TP, Lira PI, Mattos SS. The therapeutic effects of music in children following cardiac surgery. J Pediatr (Rio J). 2006;82(3):186-192.
    • (2006) J Pediatr (Rio J) , vol.82 , Issue.3 , pp. 186-192
    • Hatem, T.P.1    Lira, P.I.2    Mattos, S.S.3
  • 41
    • 38449090996 scopus 로고    scopus 로고
    • Interactive music as a treatment for pain and stress in children during venipuncture: A randomized prospective study
    • Caprilli S, Anastasi F, Grotto RP, et al. Interactive music as a treatment for pain and stress in children during venipuncture: a randomized prospective study. J Dev Behav Pediatr. 2007;28(5):399-403.
    • (2007) J Dev Behav Pediatr , vol.28 , Issue.5 , pp. 399-403
    • Caprilli, S.1    Anastasi, F.2    Grotto, R.P.3
  • 42
    • 40749136887 scopus 로고    scopus 로고
    • Music for pain and anxiety in children undergoing medical procedures: A systematic review of randomized controlled trials
    • Klassen JA, Liang Y, Tjosvold L, et al. Music for pain and anxiety in children undergoing medical procedures: a systematic review of randomized controlled trials. Ambul Pediatr. 2008;8(2):117-128.
    • (2008) Ambul Pediatr , vol.8 , Issue.2 , pp. 117-128
    • Klassen, J.A.1    Liang, Y.2    Tjosvold, L.3
  • 44
    • 0036633512 scopus 로고    scopus 로고
    • Parents? roles in using non-pharmacological methods in their child?s postoperative pain alleviation
    • Polkki T, Vehvilainen-Julkunen K, Pietila AM. Parents? roles in using non-pharmacological methods in their child?s postoperative pain alleviation. J Clin Nurs. 2002;11(4):526-536.
    • (2002) J Clin Nurs , vol.11 , Issue.4 , pp. 526-536
    • Polkki, T.1    Vehvilainen-Julkunen, K.2    Pietila, A.M.3
  • 45
    • 32944478829 scopus 로고    scopus 로고
    • Pain experiences and non-pharmacological strategies for pain management after tonsillectomy: A qualitative interview study of children and parents
    • Idvall E, Holm C, Runeson I. Pain experiences and non-pharmacological strategies for pain management after tonsillectomy: a qualitative interview study of children and parents. J Child Health Care. 2005;9(3):196-207.
    • (2005) J Child Health Care , vol.9 , Issue.3 , pp. 196-207
    • Idvall, E.1    Holm, C.2    Runeson, I.3
  • 46
    • 0036271853 scopus 로고    scopus 로고
    • Emergency analgesia in the paediatric population. Part III non-pharmacological measures of pain relief and anxiolysis
    • O'Donnell JJ, Maurice SC, Beattie TF. Emergency analgesia in the paediatric population. Part III non-pharmacological measures of pain relief and anxiolysis. Emerg Med J. 2002;19(3):195-197.
    • (2002) Emerg Med J , vol.19 , Issue.3 , pp. 195-197
    • Odonnell, J.J.1    Maurice, S.C.2    Beattie, T.F.3
  • 47
    • 0035068872 scopus 로고    scopus 로고
    • Children's distress during burn treatment is reduced by massage therapy
    • discussion 190
    • Hernandez-Reif M, Field T, Largie S, et al. Children's distress during burn treatment is reduced by massage therapy. J Burn Care Rehabil. 2001;22(2):191-195; discussion 190.
    • (2001) J Burn Care Rehabil , vol.22 , Issue.2 , pp. 191-195
    • Hernandez-Reif, M.1    Field, T.2    Largie, S.3
  • 48
    • 0023125902 scopus 로고
    • Transcutaneous electrical nerve stimulation versus oral analgesic: A randomized double-blind controlled study in acute traumatic pain
    • Ordog GJ. Transcutaneous electrical nerve stimulation versus oral analgesic: a randomized double-blind controlled study in acute traumatic pain. Am J Emerg Med. 1987;5(1):6-10.
    • (1987) Am J Emerg Med , vol.5 , Issue.1 , pp. 6-10
    • Ordog, G.J.1
  • 49
    • 0036305489 scopus 로고    scopus 로고
    • Transcutaneous electrical nerve stimulation for pain management in patients with uncomplicated minor rib fractures
    • Oncel M, Sencan S, Yildiz H, et al. Transcutaneous electrical nerve stimulation for pain management in patients with uncomplicated minor rib fractures. Eur J Cardiothorac Surg. 2002;22(1):13-17.
    • (2002) Eur J Cardiothorac Surg , vol.22 , Issue.1 , pp. 13-17
    • Oncel, M.1    Sencan, S.2    Yildiz, H.3
  • 50
    • 33947133063 scopus 로고    scopus 로고
    • A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma
    • Clark E, Plint AC, Correll R, et al. A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma. Pediatrics. 2007;119(3):460-467.
    • (2007) Pediatrics , vol.119 , Issue.3 , pp. 460-467
    • Clark, E.1    Plint, A.C.2    Correll, R.3
  • 51
    • 68149098502 scopus 로고    scopus 로고
    • Ibuprofen provides analgesia equivalent to acetaminophen-codeine in the treatment of acute pain in children with extremity injuries: A randomized clinical trial
    • Friday JH, Kanegaye JT, McCaslin I, et al. Ibuprofen provides analgesia equivalent to acetaminophen-codeine in the treatment of acute pain in children with extremity injuries: a randomized clinical trial. Acad Emerg Med. 2009;16(8):711-716.
    • (2009) Acad Emerg Med , vol.16 , Issue.8 , pp. 711-716
    • Friday, J.H.1    Kanegaye, J.T.2    McCaslin, I.3
  • 52
    • 34548737728 scopus 로고    scopus 로고
    • Effectiveness of oxycodone, ibuprofen, or the combination in the initial management of orthopedic injuryYrelated pain in children
    • Koller DM, Myers AB, Lorenz D, et al. Effectiveness of oxycodone, ibuprofen, or the combination in the initial management of orthopedic injuryYrelated pain in children. Pediatr Emerg Care. 2007;23(9):627-633.
    • (2007) Pediatr Emerg Care , vol.23 , Issue.9 , pp. 627-633
    • Koller, D.M.1    Myers, A.B.2    Lorenz, D.3
  • 53
    • 60749088409 scopus 로고    scopus 로고
    • Oxycodone versus codeine for triage pain in children with suspected forearm fracture: A randomized controlled trial
    • Charney RL, Yan Y, Schootman M, et al. Oxycodone versus codeine for triage pain in children with suspected forearm fracture: a randomized controlled trial. Pediatr Emerg Care. 2008;24(9):595-600.
    • (2008) Pediatr Emerg Care , vol.24 , Issue.9 , pp. 595-600
    • Charney, R.L.1    Yan, Y.2    Schootman, M.3
  • 54
    • 70349141330 scopus 로고    scopus 로고
    • A randomized clinical trial of ibuprofen versus acetaminophen with codeine for acute pediatric arm fracture pain
    • Drendel AL, Gorelick MH, Weisman SJ, et al. A randomized clinical trial of ibuprofen versus acetaminophen with codeine for acute pediatric arm fracture pain. Ann Emerg Med. 2009;54(4):553-560.
    • (2009) Ann Emerg Med , vol.54 , Issue.4 , pp. 553-560
    • Drendel, A.L.1    Gorelick, M.H.2    Weisman, S.J.3
  • 55
    • 13144249164 scopus 로고    scopus 로고
    • Do non-steroidal anti-inflammatory drugs adversely affect stress fracture healing? A short review
    • Wheeler P, Batt ME. Do non-steroidal anti-inflammatory drugs adversely affect stress fracture healing? A short review. Br J Sports Med. 2005;39(2):65-69.
    • (2005) Br J Sports Med , vol.39 , Issue.2 , pp. 65-69
    • Wheeler, P.1    Batt, M.E.2
  • 56
    • 23944503836 scopus 로고    scopus 로고
    • Best evidence topic report Do non-steroidal anti-inflammatory drugs cause a delay in fracture healing?
    • Clarke S, Lecky F. Best evidence topic report. Do non-steroidal anti-inflammatory drugs cause a delay in fracture healing? Emerg Med J. 2005;22(9):652-653.
    • (2005) Emerg Med J , vol.22 , Issue.9 , pp. 652-653
    • Clarke, S.1    Lecky, F.2
  • 57
    • 0034853632 scopus 로고    scopus 로고
    • The pharmacogenetics of analgesia: Toward a genetically-based approach to pain management
    • Flores CM, Mogil JS. The pharmacogenetics of analgesia: toward a genetically-based approach to pain management. Pharmacogenomics. 2001;2(3):177-194.
    • (2001) Pharmacogenomics , vol.2 , Issue.3 , pp. 177-194
    • Flores, C.M.1    Mogil, J.S.2
  • 59
    • 32944461710 scopus 로고    scopus 로고
    • Interethnic differences in genetic polymorphisms of CYP2D6 in the U.S. population: Clinical implications
    • Bernard S, Neville KA, Nguyen AT, et al. Interethnic differences in genetic polymorphisms of CYP2D6 in the U.S. population: clinical implications. Oncologist. 2006;11(2):126-135.
    • (2006) Oncologist , vol.11 , Issue.2 , pp. 126-135
    • Bernard, S.1    Neville, K.A.2    Nguyen, A.T.3
  • 60
    • 13544249943 scopus 로고    scopus 로고
    • Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): Clinical consequences, evolutionary aspects and functional diversity
    • Ingelman-Sundberg M. Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity. Pharmacogenomics J. 2005;5(1):6-13.
    • (2005) Pharmacogenomics J , vol.5 , Issue.1 , pp. 6-13
    • Ingelman-Sundberg, M.1
  • 61
    • 33847031732 scopus 로고    scopus 로고
    • CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure
    • Sistonen J, Sajantila A, Lao O, et al. CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure. Pharmacogenet Genomics. 2007;17(2):93-101.
    • (2007) Pharmacogenet Genomics , vol.17 , Issue.2 , pp. 93-101
    • Sistonen, J.1    Sajantila, A.2    Lao, O.3
  • 62
    • 0036124107 scopus 로고    scopus 로고
    • CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
    • Bradford LD. CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics. 2002;3(2):229-243.
    • (2002) Pharmacogenomics , vol.3 , Issue.2 , pp. 229-243
    • Bradford, L.D.1
  • 63
    • 0024306112 scopus 로고
    • Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation
    • Yue QY, Svensson JO, Alm C, et al. Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation. Br J Clin Pharmacol. 1989;28(6):639-645.
    • (1989) Br J Clin Pharmacol , vol.28 , Issue.6 , pp. 639-645
    • Yue, Q.Y.1    Svensson, J.O.2    Alm, C.3
  • 64
    • 0025853291 scopus 로고
    • Disposition and metabolism of codeine after single and chronic doses in one poor and seven extensive metabolisers
    • Chen ZR, Somogyi AA, Reynolds G, et al. Disposition and metabolism of codeine after single and chronic doses in one poor and seven extensive metabolisers. Br J Clin Pharmacol. 1991;31(4):381-390.
    • (1991) Br J Clin Pharmacol , vol.31 , Issue.4 , pp. 381-390
    • Chen, Z.R.1    Somogyi, A.A.2    Reynolds, G.3
  • 65
    • 0023795013 scopus 로고
    • Polymorphic O-demethylation of codeine
    • Chen ZR, Somogyi AA, Bochner F. Polymorphic O-demethylation of codeine. Lancet. 1988;2(8616):914-915.
    • (1988) Lancet , vol.2 , Issue.8616 , pp. 914-915
    • Chen, Z.R.1    Somogyi, A.A.2    Bochner, F.3
  • 66
    • 0025649038 scopus 로고
    • Codeine increases pain thresholds to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine
    • Sindrup SH, Brosen K, Bjerring P, et al. Codeine increases pain thresholds to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine. Clin Pharmacol Ther. 1990;48(6):686-693.
    • (1990) Clin Pharmacol Ther , vol.48 , Issue.6 , pp. 686-693
    • Sindrup, S.H.1    Brosen, K.2    Bjerring, P.3
  • 67
    • 0028923152 scopus 로고
    • Patient-controlled analgesia (PCA) with codeine for postoperative pain relief in ten extensive metabolisers and one poor metaboliser of dextromethorphan
    • Persson K, Sjostrom S, Sigurdardottir I, et al. Patient-controlled analgesia (PCA) with codeine for postoperative pain relief in ten extensive metabolisers and one poor metaboliser of dextromethorphan. Br J Clin Pharmacol. 1995;39(2):182-186.
    • (1995) Br J Clin Pharmacol , vol.39 , Issue.2 , pp. 182-186
    • Persson, K.1    Sjostrom, S.2    Sigurdardottir, I.3
  • 68
    • 0031679974 scopus 로고    scopus 로고
    • Codeine in post-operative pain. Study of the influence of sparteine phenotype and serum concentrations of morphine and morphine-6-glucuronide
    • Poulsen L, Riishede L, Brosen K, et al. Codeine in post-operative pain. Study of the influence of sparteine phenotype and serum concentrations of morphine and morphine-6-glucuronide. Eur J Clin Pharmacol. 1998;54(6):451-454.
    • (1998) Eur J Clin Pharmacol , vol.54 , Issue.6 , pp. 451-454
    • Poulsen, L.1    Riishede, L.2    Brosen, K.3
  • 69
    • 0031746749 scopus 로고    scopus 로고
    • Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation
    • Eckhardt K, Li S, Ammon S, et al. Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation. Pain. 1998;76(1-2):27-33.
    • (1998) Pain , vol.76 , Issue.1-2 , pp. 27-33
    • Eckhardt, K.1    Li, S.2    Ammon, S.3
  • 70
    • 0030432381 scopus 로고    scopus 로고
    • Pharmacogenetic determination of the effects of codeine and prediction of drug interactions
    • Caraco Y, Sheller J, Wood AJ. Pharmacogenetic determination of the effects of codeine and prediction of drug interactions. J Pharmacol Exp Ther. 1996;278(3):1165-1174.
    • (1996) J Pharmacol Exp Ther , vol.278 , Issue.3 , pp. 1165-1174
    • Caraco, Y.1    Sheller, J.2    Wood, A.J.3
  • 71
    • 0030948340 scopus 로고    scopus 로고
    • Effect of codeine on gastrointestinal motility in relation to CYP2D6 phenotype
    • Mikus G, Trausch B, Rodewald C, et al. Effect of codeine on gastrointestinal motility in relation to CYP2D6 phenotype. Clin Pharmacol Ther. 1997;61(4):459-466.
    • (1997) Clin Pharmacol Ther , vol.61 , Issue.4 , pp. 459-466
    • Mikus, G.1    Trausch, B.2    Rodewald, C.3
  • 72
    • 9844239377 scopus 로고    scopus 로고
    • The effect of codeine on gastrointestinal transit in extensive and poor metabolisers of debrisoquine
    • Hasselstrom J, Yue QY, Sawe J. The effect of codeine on gastrointestinal transit in extensive and poor metabolisers of debrisoquine. Eur J Clin Pharmacol. 1997;53(2):145-148.
    • (1997) Eur J Clin Pharmacol , vol.53 , Issue.2 , pp. 145-148
    • Hasselstrom, J.1    Yue, Q.Y.2    Sawe, J.3
  • 73
    • 67349239976 scopus 로고    scopus 로고
    • Drug dosing error with drops: Severe clinical course of codeine intoxication in twins
    • Hermanns-Clausen M, Weinmann W, Auwarter V, et al. Drug dosing error with drops: severe clinical course of codeine intoxication in twins. Eur J Pediatr. 2009;168(7):819-824.
    • (2009) Eur J Pediatr , vol.168 , Issue.7 , pp. 819-824
    • Hermanns-Clausen, M.1    Weinmann, W.2    Auwarter, V.3
  • 74
    • 33846465345 scopus 로고    scopus 로고
    • Safety of codeine during breastfeeding: Fatal morphine poisoning in the breastfed neonate of a mother prescribed codeine
    • Madadi P, Koren G, Cairns J, et al. Safety of codeine during breastfeeding: fatal morphine poisoning in the breastfed neonate of a mother prescribed codeine. Can Fam Physician. 2007;53(1):33-35.
    • (2007) Can Fam Physician , vol.53 , Issue.1 , pp. 33-35
    • Madadi, P.1    Koren, G.2    Cairns, J.3
  • 76
    • 0242543259 scopus 로고    scopus 로고
    • Clinical relevance of genetic polymorphisms in the human CYP2C9 gene
    • Schwarz UI. Clinical relevance of genetic polymorphisms in the human CYP2C9 gene. Eur J Clin Invest. 2003;33(suppl 2):23-30.
    • (2003) Eur J Clin Invest , vol.33 , Issue.SUPPL. 2 , pp. 23-30
    • Schwarz, U.I.1
  • 77
    • 33646205301 scopus 로고    scopus 로고
    • Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals
    • Garcia-Martin E, Martinez C, Ladero JM, et al. Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals. Mol Diagn Ther. 2006;10(1):29-40.
    • (2006) Mol Diagn Ther , vol.10 , Issue.1 , pp. 29-40
    • Garcia-Martin, E.1    Martinez, C.2    Ladero, J.M.3
  • 78
    • 0036336114 scopus 로고    scopus 로고
    • Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2
    • Kirchheiner J, Meineke I, Freytag G, et al. Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2. Clin Pharmacol Ther. 2002;72(1):62-75.
    • (2002) Clin Pharmacol Ther , vol.72 , Issue.1 , pp. 62-75
    • Kirchheiner, J.1    Meineke, I.2    Freytag, G.3
  • 79
    • 11144300168 scopus 로고    scopus 로고
    • The effect of the cytochrome P450 CYP2C8 polymorphism on the disposition of (R)-ibuprofen enantiomer in healthy subjects
    • Martinez C, Garcia-Martin E, Blanco G, et al. The effect of the cytochrome P450 CYP2C8 polymorphism on the disposition of (R)-ibuprofen enantiomer in healthy subjects. Br J Clin Pharmacol. 2005;59(1):62-69.
    • (2005) Br J Clin Pharmacol , vol.59 , Issue.1 , pp. 62-69
    • Martinez, C.1    Garcia-Martin, E.2    Blanco, G.3


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