Modified bacterial cellulose scaffolds for localized doxorubicin release in human colorectal HT-29 cells

Colloids and Surfaces B: Biointerfaces

Volumn 140, Issue , 2016, Pages 421-429

  L Cacicedo, Maximiliano ^a   E León, Ignacio ^b   S Gonzalez, Jimena ^c   M Porto, Luismar ^d   A Alvarez, Vera ^c   Castro, Guillermo R ^a  

^a Universidad Nacional de La Plata   (Argentina)

^b UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

^c UNIVERSIDAD NACIONAL DE MAR DEL PLATA   (Argentina)

^d FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Alginate; Bacterial cellulose; Cancer therapy; Doxorubicin; Drug delivery; Human colorectal HT 29 cells; Nanocomposite

Indexed keywords

ALGINATE; AMORPHOUS FILMS; BIOPOLYMERS; BORON CARBIDE; CELL CULTURE; CELLS; CELLULOSE; CELLULOSE FILMS; CYTOLOGY; DRUG DELIVERY; GAS ADSORPTION; NANOCOMPOSITES; PORE SIZE; SCANNING ELECTRON MICROSCOPY; THERMOGRAVIMETRIC ANALYSIS; X RAY DIFFRACTION;

BACTERIAL CELLULOSE; BRUNAUER-EMMETT-TELLER METHOD; CANCER THERAPY; COLORECTAL ADENOCARCINOMA; DOXORUBICIN; GLUCONACETOBACTER HANSENII; HT-29 CELLS; NITROGEN ADSORPTION ISOTHERM;

SCAFFOLDS (BIOLOGY);

BACTERIAL CELLULOSE; BIOPOLYMER; CELLULOSE; DOXORUBICIN; NANOCOMPOSITE; UNCLASSIFIED DRUG; ALGINIC ACID; ANTINEOPLASTIC ANTIBIOTIC; GLUCURONIC ACID; HEXURONIC ACID;

ADSORPTION; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOCOMPATIBILITY; CELL DAMAGE; CELL VIABILITY; COLORECTAL CARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; ENCAPSULATION; GLUCONACETOBACTER; GLUCONACETOBACTER HANSENII; HT 29 CELL LINE; HUMAN; HUMAN CELL; HYDROPHILICITY; INFRARED SPECTROSCOPY; ISOTHERM; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; THERMOGRAVIMETRY; THERMOSTABILITY; X RAY DIFFRACTION; CELL SURVIVAL; CHEMISTRY; COLORECTAL TUMOR; DRUG EFFECTS; HT-29 CELL LINE; METABOLISM; PATHOLOGY; TISSUE SCAFFOLD; ULTRASTRUCTURE;

BACTERIA; CELLS; CELLULOSE; DISEASES;

ALGINATES; ANTIBIOTICS, ANTINEOPLASTIC; CELL SURVIVAL; CELLULOSE; COLORECTAL NEOPLASMS; DOXORUBICIN; DRUG LIBERATION; GLUCONACETOBACTER; GLUCURONIC ACID; HEXURONIC ACIDS; HT29 CELLS; HUMANS; MICROSCOPY, ELECTRON, SCANNING; NANOCOMPOSITES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THERMOGRAVIMETRY; TISSUE SCAFFOLDS; X-RAY DIFFRACTION;

EID: 84954286279     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2016.01.007     Document Type: Article

References (40)

1. WHO Cancer, (n.d.). (accessed 18.11.15). http://www.who.int/mediacentre/factsheets/fs297/en/.
2. Wolinsky J.B., Colson Y.L., Grinstaff M.W. Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers. J. Control. Release 2012, 159:14-26. 10.1016/j.jconrel.2011.11.031.
3. Xu J., Zhao Q., Jin Y., Qiu L. High loading of hydrophilic/hydrophobic doxorubicin into polyphosphazene polymersome for breast cancer therapy. Nanomed. Nanotechnol. Biol. Med. 2014, 10:349-358. 10.1016/j.nano.2013.08.004.
4. Dallas L., Xia F., Fan M.J., Gray P., et al. Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition. Cancer Res. 2009, 69:1951-1957. 10.1158/0008-5472.CAN-08-2023.
5. Gelderblom H., Verweij J., Nooter K., Sparreboom A. Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation. Eur. J. Cancer 2001, 37:1590-1598. 10.1016/S0959-8049(01) 00171-X.
6. Thorn C.F., Oshiro C., Marsh S., Hernandez-Boussard T., McLeod H., Klein T.E., Altman R.B. Doxorubicin pathways:pharmacodynamics and adverse effects. Pharmacogenet. Genomics 2012, 21:440-446. 10.1097/FPC.0b013e32833ffb56.Doxorubicin.
7. Moses M.A., Brem H., Langer R. Advancing the field of drug delivery: taking aim at cancer. Cancer Cell 2003, 4:337-341. 10.1016/S1535-6108(03)00276-9.
8. Chiu B., Coburn J., Pilichowska M., Holcroft C., Seib F.P., Charest A., et al. Surgery combined with controlled-release doxorubicin silk films as a treatment strategy in an orthotopic neuroblastoma mouse model. Br. J. Cancer 2014, 111:708-715. 10.1038/bjc.2014.324.
9. Focal treatment of primary breast cancer Adv. Funct. Mater. 2013, 23:58-65. 10.1002/adfm.201201238.
10. Rehm B.H.A. Alginates: Biology and Applications 2009, Springer, Dordrecht.
11. Castro G.R., Kamdar R.R., Panilaitis B., Kaplan D.L. Triggered release of proteins from emulsan-alginate beads. J. Control. Release 2005, 109:149-157. 10.1016/j.jconrel.2005.09.042.
12. Dini C., Islan G.A., de Urraza P.J., Castro G.R. Novel biopolymer matrices for microencapsulation of phages: enhanced protection against acidity and protease activity. Macromol. Biosci. 2012, 12:1200-1208. 10.1002/mabi.201200109.
13. Islan G.A., De Verti I.P., Marchetti S.G., Castro G.R. Studies of ciprofloxacin encapsulation on alginate/pectin matrixes and its relationship with biodisponibility. Appl. Biochem. Biotechnol. 2012, 167:1408-1420. 10.1007/s12010-012-9610-2.
14. Abeer M.M., Mohd Amin M.C.I., Martin C. A review of bacterial cellulose-based drug delivery systems: their biochemistry, current approaches and future prospects. J. Pharm. Pharmacol. 2014, 66:1047-1061. 10.1111/jphp.12234.
15. Bodin A., Backdahl H., Fink H., Gustafsson L., Risberg B., Gatenholm P. Influence of cultivation conditions on mechanical and morphological properties of bacterial cellulose tubes. Biotechnol. Bioeng. 2007, 97:425-434. 10.1002/bit.
16. C. for D.E. and Research, Guidances (Drugs)-Guidance for Industry: Pyrogen and Endotoxins Testing: Questions and Answers, (n.d.). (accessed 18.11.15). http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm314718.htm.
17. 3 hybrid microparticles on bacterial cellulose films for doxorubicin sustained delivery. J. Appl. Biomed. 2015, 13:239-248. 10.1016/j.jab.2015.03.004.
18. Shah N., Ul-Islam M., Khattak W.A., Park J.K. Overview of bacterial cellulose composites: a multipurpose advanced material. Carbohydr. Polym. 2013, 98:1585-1598. 10.1016/j.carbpol.2013.08.018.
19. Bosio V.E., Machain V., López A.G., De Berti I.O.P., Marchetti S.G., Mechetti M., Castro G.R. Binding and encapsulation of doxorubicin on smart pectin hydrogels for oral delivery. Appl. Biochem. Biotechnol. 2012, 167:1365-1376. 10.1007/s12010-012-9641-8.
20. Chiaoprakobkij N., Sanchavanakit N., Subbalekha K., Pavasant P., Phisalaphong M. Characterization and biocompatibility of bacterial cellulose/alginate composite sponges with human keratinocytes and gingival fibroblasts. Carbohydr. Polym. 2011, 85:548-553. 10.1016/j.carbpol.2011.03.011.
21. Kirdponpattara S., Khamkeaw A., Sanchavanakit N., Pavasant P., Phisalaphong M. Structural modification and characterization of bacterial cellulose-alginate composite scaffolds for tissue engineering. Carbohydr. Polym. 2015, 132:146-155. 10.1016/j.carbpol.2015.06.059.
22. Park M., Lee D., Hyun J. Nanocellulose-alginate hydrogel for cell encapsulation. Carbohydr. Polym. 2015, 116:223-228. 10.1016/j.carbpol.2014.07.059.
23. Shao W., Liu H., Liu X., Wang S., Wu J., Zhang R., et al. Development of silver sulfadiazine loaded bacterial cellulose/sodium alginate composite films with enhanced antibacterial property. Carbohydr. Polym. 2015, 132:351-358. 10.1016/j.carbpol.2015.06.057.
24. Zhou L.L., Sun D.P., Hu L.Y., Li Y.W., Yang J.Z. Effect of addition of sodium alginate on bacterial cellulose production by Acetobacter xylinum. J. Ind. Microbiol. Biotechnol. 2007, 34:483-489. 10.1007/s10295-007-0218-4.
25. Okajima T., Keiko N., Heping Z., Ling N., Tanabe T., Yasuda T., et al. Sensitive colorimetric bioassays for insulin-like growth factor (IGF) stimulation of cell proliferation and glucose consumption: use in studies of IGF analogs. Endocrinology 1992, 130:2201-2212.
26. Leon I.E., Porro V., Di Virgilio A.L., Naso L.G., Williams P.A.M., Bollati-Fogolín M., et al. Antiproliferative and apoptosis-inducing activity of an oxidovanadium(IV) complex with the flavonoid silibinin against osteosarcoma cells. J. Biol. Inorg. Chem. 2014, 19:59-74. 10.1007/s00775-013-1061-x.
27. Lourdin D., Coignard L., Bizot H., Colonna P. Influence of equilibrium relative humidity and plasticizer concentration on the water content and glass transition of starch materials. Polymer (Guildf) 1997, 38:5401-5406. 10.1016/S0032-3861(97)00082-7.
28. Ouajai S., Shanks R.A. Composition, structure and thermal degradation of hemp cellulose after chemical treatments. Polym. Degrad. Stab. 2005, 89:327-335. 10.1016/j.polymdegradstab.2005.01.016.
29. Huang H.C., Chen L.C., Bin Lin S., Chen H.H. Nano-biomaterials application: in situ modification of bacterial cellulose structure by adding HPMC during fermentation. Carbohydr. Polym. 2011, 83:979-987. 10.1016/j.carbpol.2010.09.011.
30. Cai Z., Kim J. Bacterial cellulose/poly(ethylene glycol) composite: characterization and first evaluation of biocompatibility. Cellulose 2010, 17:83-91. 10.1007/s10570-009-9362-5.
31. Kwak M.H., Kim J.E., Go J., Koh E.K., Song S.H., Son H.J., et al. Bacterial cellulose membrane produced by Acetobacter sp. A10 for burn wound dressing applications. Carbohydr. Polym. 2015, 122:387-398. 10.1016/j.carbpol.2014.10.049.
32. Kacuráková M. FTIR study of plant cell wall model compounds: pectic polysaccharides and hemicelluloses. Carbohydr. Polym. 2000, 43:195-203. 10.1016/S0144-8617(00)00151-X.
33. Daemi H., Barikani M. Synthesis and characterization of calcium alginate nanoparticles, sodium homopolymannuronate salt and its calcium nanoparticles. Sci. Iran 2012, 19:2023-2028. 10.1016/j.scient.2012.10.005.
34. Gonçalves M., Figueira P., Maciel D., Rodrigues J., Shi X., Tomás H., et al. Antitumor efficacy of doxorubicin-loaded laponite/alginate hybrid hydrogels. Macromol. Biosci. 2014, 14:110-120. 10.1002/mabi.201300241.
35. Mahoney B.P., Raghunand N., Baggett B., Gillies R.J. Tumor acidity, ion trapping and chemotherapeutics. Biochem. Pharmacol. 2003, 66:1207-1218. 10.1016/S0006-2952(03)00467-2.
36. Arias J.L., Ruiz M.A., López-Viota M., Delgado V.Á. Poly(alkylcyanoacrylate) colloidal particles as vehicles for antitumour drug delivery: a comparative study. Colloids Surf. B Biointerfaces 2008, 62:64-70. 10.1016/j.colsurfb.2007.09.018.
37. Zhu Y., Shi J., Li Y., Chen H., Shen W., Dong X.-P. Hollow mesoporous spheres with cubic pore network as a potential carrier for drug storage and its in vitro release kinetics. J. Mater. Res. 2004, 20:54-61. 10.1557/JMR.2005.0035.
38. Ahern R.J., Hanrahan J.P., Tobin J.M., Ryan K.B., Crean A.M. Comparison of fenofibrate-mesoporous silica drug-loading processes for enhanced drug delivery. Eur. J. Pharm. Sci. 2013, 50:400-409. 10.1016/j.ejps.2013.08.026.
39. A-sasutjarit R., Sirivat A., Vayumhasuwan P. Viscoelastic properties of Carbopol 940 gels and their relationships to piroxicam diffusion coefficients in gel bases. Pharm. Res. 2005, 22:2134-2140. 10.1007/s11095-005-8244-2.
40. Trovatti E., Freire C.S.R., Pinto P.C., Almeida I.F., Costa P., Silvestre A.J.D., et al. Bacterial cellulose membranes applied in topical and transdermal delivery of lidocaine hydrochloride and ibuprofen: in vitro diffusion studies. Int. J. Pharm. 2012, 435:83-87. 10.1016/j.ijpharm.2012.01.002.