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Volumn 13, Issue 1, 2016, Pages 13-20

Methylene blue exerts a neuroprotective effect against traumatic brain injury by promoting autophagy and inhibiting microglial activation

Author keywords

Autophagy; Methylene blue; Microglia; Traumatic brain injury

Indexed keywords

BECLIN 1; METHYLENE BLUE; NEUROPROTECTIVE AGENT;

EID: 84954243597     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4551     Document Type: Article
Times cited : (48)

References (40)
  • 4
    • 84872528255 scopus 로고    scopus 로고
    • Animal models of traumatic brain injury
    • Xiong Y, Mahmood A and Chopp M: Animal models of traumatic brain injury. Nat Rev Neurosci 14: 128-142, 2013.
    • (2013) Nat Rev Neurosci , vol.14 , pp. 128-142
    • Xiong, Y.1    Mahmood, A.2    Chopp, M.3
  • 5
    • 84908221239 scopus 로고    scopus 로고
    • Therapeutic benefits of methylene blue on cognitive impairment during chronic cerebral hypoperfusion
    • Auchter A, Williams J, Barksdale B, Monfils MH and Gonzalez-Lima F: Therapeutic benefits of methylene blue on cognitive impairment during chronic cerebral hypoperfusion. J Alzheimers Dis 42 Suppl 4: S525-S535, 2014.
    • (2014) J Alzheimers Dis , vol.42 , pp. S525-S535
    • Auchter, A.1    Williams, J.2    Barksdale, B.3    Monfils, M.H.4    Gonzalez-Lima, F.5
  • 6
    • 33750508313 scopus 로고    scopus 로고
    • Use of methylene blue in sepsis: A systematic review
    • Kwok ES and Howes D: Use of methylene blue in sepsis: A systematic review. J Intensive Care Med 21: 359-363, 2006.
    • (2006) J Intensive Care Med , vol.21 , pp. 359-363
    • Kwok, E.S.1    Howes, D.2
  • 7
    • 33745865227 scopus 로고    scopus 로고
    • The hemodynamic effects of methylene blue when administered at the onset of cardiopulmonary bypass
    • Maslow AD, Stearns G, Butala P, Schwartz CS, Gough J and Singh AK: The hemodynamic effects of methylene blue when administered at the onset of cardiopulmonary bypass. Anesth Analg 103: 2-8, 2006.
    • (2006) Anesth Analg , vol.103 , pp. 2-8
    • Maslow, A.D.1    Stearns, G.2    Butala, P.3    Schwartz, C.S.4    Gough, J.5    Singh, A.K.6
  • 9
    • 82655179828 scopus 로고    scopus 로고
    • Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue
    • Rojas JC, Bruchey AK and Gonzalez-Lima F: Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue. Prog Neurobiol 96: 32-45, 2012.
    • (2012) Prog Neurobiol , vol.96 , pp. 32-45
    • Rojas, J.C.1    Bruchey, A.K.2    Gonzalez-Lima, F.3
  • 11
    • 84894344975 scopus 로고    scopus 로고
    • Neuroprotective efficacy of methylene blue in ischemic stroke: An MRI study
    • Shen Q, Du F, Huang S, Rodriguez P, Watts LT and Duong TQ: Neuroprotective efficacy of methylene blue in ischemic stroke: An MRI study. PLoS One 8: e79833, 2013.
    • (2013) PLoS One , vol.8 , pp. e79833
    • Shen, Q.1    Du, F.2    Huang, S.3    Rodriguez, P.4    Watts, L.T.5    Duong, T.Q.6
  • 14
    • 78149399227 scopus 로고    scopus 로고
    • The role of Nrf2 signaling in the regulation of antioxidants and detoxifying enzymes after traumatic brain injury in rats and mice
    • Hong Y, Yan W, Chen S, Sun CR and Zhang JM: The role of Nrf2 signaling in the regulation of antioxidants and detoxifying enzymes after traumatic brain injury in rats and mice. Acta Pharmacol Sin 31: 1421-1430, 2010.
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 1421-1430
    • Hong, Y.1    Yan, W.2    Chen, S.3    Sun, C.R.4    Zhang, J.M.5
  • 16
    • 0035167706 scopus 로고    scopus 로고
    • Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats
    • Chen J, Sanberg PR, Li Y, Wang L, Lu M, Willing AE, Sanchez-Ramos J and Chopp M: Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats. Stroke 32: 2682-2688, 2001.
    • (2001) Stroke , vol.32 , pp. 2682-2688
    • Chen, J.1    Sanberg, P.R.2    Li, Y.3    Wang, L.4    Lu, M.5    Willing, A.E.6    Sanchez-Ramos, J.7    Chopp, M.8
  • 17
    • 84887389490 scopus 로고    scopus 로고
    • Inhibition of cathepsin S produces neuroprotective effects after traumatic brain injury in mice
    • Xu J, Wang H, Ding K, Lu X, Li T, Wang J, Wang C and Wang J: Inhibition of cathepsin S produces neuroprotective effects after traumatic brain injury in mice. Mediators Inflamm 2013: 187873, 2013.
    • (2013) Mediators Inflamm , vol.2013 , pp. 187873
    • Xu, J.1    Wang, H.2    Ding, K.3    Lu, X.4    Li, T.5    Wang, J.6    Wang, C.7    Wang, J.8
  • 18
    • 84904283357 scopus 로고    scopus 로고
    • Intravenous administration of Honokiol provides neuroprotection and improves functional recovery after traumatic brain injury through cell cycle inhibition
    • Wang H, Liao Z, Sun X, Shi Q, Huo G, Xie Y, Tang X, Zhi X and Tang Z: Intravenous administration of Honokiol provides neuroprotection and improves functional recovery after traumatic brain injury through cell cycle inhibition. Neuropharmacology 86: 9-21, 2014.
    • (2014) Neuropharmacology , vol.86 , pp. 9-21
    • Wang, H.1    Liao, Z.2    Sun, X.3    Shi, Q.4    Huo, G.5    Xie, Y.6    Tang, X.7    Zhi, X.8    Tang, Z.9
  • 19
    • 84890117063 scopus 로고    scopus 로고
    • Melatonin-enhanced autophagy protects against neural apoptosis via a mitochondrial pathway in early brain injury following a subarachnoid hemorrhage
    • Chen J, Wang L, Wu C, Hu Q, Gu C, Yan F, Li J, Yan W and Chen G: Melatonin-enhanced autophagy protects against neural apoptosis via a mitochondrial pathway in early brain injury following a subarachnoid hemorrhage. J Pineal Res 56: 12-19, 2014.
    • (2014) J Pineal Res , vol.56 , pp. 12-19
    • Chen, J.1    Wang, L.2    Wu, C.3    Hu, Q.4    Gu, C.5    Yan, F.6    Li, J.7    Yan, W.8    Chen, G.9
  • 22
    • 84858742061 scopus 로고    scopus 로고
    • Traumatic brain injury: A risk factor for Alzheimer's disease
    • Sivanandam TM and Thakur MK: Traumatic brain injury: A risk factor for Alzheimer's disease. Neurosci Biobehav Rev 36: 1376-1381, 2012.
    • (2012) Neurosci Biobehav Rev , vol.36 , pp. 1376-1381
    • Sivanandam, T.M.1    Thakur, M.K.2
  • 23
    • 84884551647 scopus 로고    scopus 로고
    • Post-traumatic malignant glioma in a pregnant woman: Case report and review of the literature
    • Han Z, Du Y, Qi H and Yin W: Post-traumatic malignant glioma in a pregnant woman: Case report and review of the literature. Neurol Med Chir (Tokyo) 53: 630-634, 2013.
    • (2013) Neurol Med Chir (Tokyo) , vol.53 , pp. 630-634
    • Han, Z.1    Du, Y.2    Qi, H.3    Yin, W.4
  • 24
    • 84867213778 scopus 로고    scopus 로고
    • Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention
    • Kumar A and Loane DJ: Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention. Brain Behav Immun 26: 1191-1201, 2012.
    • (2012) Brain Behav Immun , vol.26 , pp. 1191-1201
    • Kumar, A.1    Loane, D.J.2
  • 28
    • 0037382181 scopus 로고    scopus 로고
    • Effects of magnesium administration on brain edema and blood-brain barrier breakdown after experimental traumatic brain injury in rats
    • Esen F, Erdem T, Aktan D, Kalayci R, Cakar N, Kaya M and Telci L: Effects of magnesium administration on brain edema and blood-brain barrier breakdown after experimental traumatic brain injury in rats. J Neurosurg Anesthesiol 15: 119-125, 2003.
    • (2003) J Neurosurg Anesthesiol , vol.15 , pp. 119-125
    • Esen, F.1    Erdem, T.2    Aktan, D.3    Kalayci, R.4    Cakar, N.5    Kaya, M.6    Telci, L.7
  • 29
    • 0030693706 scopus 로고    scopus 로고
    • Contribution of vasogenic and cellular edema to traumatic brain swelling measured by diffusion-weighted imaging
    • Barzo P, Marmarou A, Fatouros P, Hayasaki K and Corwin F: Contribution of vasogenic and cellular edema to traumatic brain swelling measured by diffusion-weighted imaging. J Neurosurg 87: 900-907, 1997.
    • (1997) J Neurosurg , vol.87 , pp. 900-907
    • Barzo, P.1    Marmarou, A.2    Fatouros, P.3    Hayasaki, K.4    Corwin, F.5
  • 30
    • 84883879660 scopus 로고    scopus 로고
    • Microglial activation induced by traumatic brain injury is suppressed by postinjury treatment with hyperbaric oxygen therapy
    • Lim SW, Wang CC, Wang YH, Chio CC, Niu KC and Kuo JR: Microglial activation induced by traumatic brain injury is suppressed by postinjury treatment with hyperbaric oxygen therapy. J Surg Res 184: 1076-1084, 2013.
    • (2013) J Surg Res , vol.184 , pp. 1076-1084
    • Lim, S.W.1    Wang, C.C.2    Wang, Y.H.3    Chio, C.C.4    Niu, K.C.5    Kuo, J.R.6
  • 34
    • 0142103693 scopus 로고    scopus 로고
    • Methylene blue blocks cGMP production and disrupts directed migration of microglia to nerve lesions in the leech CNS
    • Duan Y, Haugabook SJ, Sahley CL and Muller KJ: Methylene blue blocks cGMP production and disrupts directed migration of microglia to nerve lesions in the leech CNS. J Neurobiol 57: 183-192, 2003.
    • (2003) J Neurobiol , vol.57 , pp. 183-192
    • Duan, Y.1    Haugabook, S.J.2    Sahley, C.L.3    Muller, K.J.4
  • 36
    • 0031912589 scopus 로고    scopus 로고
    • Nitric oxide and cyclic GMP regulate retinal patterning in the optic lobe of Drosophila
    • Gibbs SM and Truman JW: Nitric oxide and cyclic GMP regulate retinal patterning in the optic lobe of Drosophila. Neuron 20: 83-93, 1998.
    • (1998) Neuron , vol.20 , pp. 83-93
    • Gibbs, S.M.1    Truman, J.W.2
  • 37
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • Levine B and Klionsky DJ: Development by self-digestion: Molecular mechanisms and biological functions of autophagy. Dev Cell 6: 463-477, 2004.
    • (2004) Dev Cell , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 40
    • 77952332824 scopus 로고    scopus 로고
    • Inhibition of hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation
    • Wang AM, Morishima Y, Clapp KM, Peng HM, Pratt WB, Gestwicki JE, Osawa Y and Lieberman AP: Inhibition of hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation. J Biol Chem 285: 15714-15723, 2010
    • (2010) J Biol Chem , vol.285 , pp. 15714-15723
    • Wang, A.M.1    Morishima, Y.2    Clapp, K.M.3    Peng, H.M.4    Pratt, W.B.5    Gestwicki, J.E.6    Osawa, Y.7    Lieberman, A.P.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.