Depletion of intracellular thiols and increased production of 4-Hydroxynonenal that occur during cryopreservation of stallion spermatozoa lead to caspase activation, loss of motility, and cell death

Biology of Reproduction

Volumn 93, Issue 6, 2015, Pages

  Muñoz, Patricia Martin ^a   Ferrusola, Cristina Ortega ^a   Vizuete, Guillermo ^a   Dávila, Maria Plaza ^a   Martinez, Heriberto Rodriguez ^b   Peña, Fernando J ^a  

^a UNIVERSITY OF EXTREMADURA   (Spain)

^b LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Cryopreservation; Donkeys; Equids (Horses; Flow cytometry; ROS; Semen; Sperm; Sperm senescence; Spermatozoa; Stallion; Thiols; Zebras)

Indexed keywords

4-HYDROXY-2-NONENAL; ALDEHYDE; CASPASE 3; CASPASE 7; REACTIVE OXYGEN METABOLITE; THIOL DERIVATIVE;

ANIMAL; CELL DEATH; CRYOPRESERVATION; CYTOLOGY; HORSE; INTRACELLULAR SPACE; LIPID PEROXIDATION; MALE; METABOLISM; OXIDATIVE STRESS; PHOSPHORYLATION; PHYSIOLOGY; PROCEDURES; SPERM PRESERVATION; SPERMATOZOON; SPERMATOZOON MOTILITY;

ALDEHYDES; ANIMALS; CASPASE 3; CASPASE 7; CELL DEATH; CRYOPRESERVATION; HORSES; INTRACELLULAR SPACE; LIPID PEROXIDATION; MALE; OXIDATIVE STRESS; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; SEMEN PRESERVATION; SPERM MOTILITY; SPERMATOZOA; SULFHYDRYL COMPOUNDS;

EID: 84954205457     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.115.132878     Document Type: Article

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