The non-structural protein of Crimean-Congo hemorrhagic fever virus disrupts the mitochondrial membrane potential and induces apoptosis

Journal of Biological Chemistry

Volumn 291, Issue 2, 2016, Pages 582-592

  Barnwal, Bhaskar ^a,b   Karlberg, Helen ^c   Mirazimi, Ali ^c,d,e   Tan, Yee Joo ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^c SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

^d KAROLINSKA INSTITUTE   (Sweden)

^e NATIONAL VETERINARY INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL CULTURE; CELL MEMBRANES; MAGNESIUM PRINTING PLATES; MITOCHONDRIA; PROTEINS; VIRUSES;

AMINO ACID RESIDUES; ECTOPIC EXPRESSIONS; INDUCED APOPTOSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANES; MULTIPLE FACTORS; SPECIFIC INHIBITORS; VIRAL INFECTIONS;

CELL DEATH;

ALANINE; CASPASE 3; CASPASE 7; LEUCINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; VIRUS PROTEIN; MUTANT PROTEIN; VIRAL PROTEIN;

AMINO ACID COMPOSITION; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CRIMEAN CONGO HEMORRHAGIC FEVER; CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RESIDUE ANALYSIS; VIRUS CELL INTERACTION; VIRUS REPLICATION; AMINO ACID SEQUENCE; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; DRUG EFFECTS; GENETIC TRANSFECTION; METABOLISM; MOLECULAR GENETICS; NAIROVIRUS; SIGNAL TRANSDUCTION; TUMOR CELL LINE; VIROLOGY;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CELL LINE, TUMOR; HEMORRHAGIC FEVER VIRUS, CRIMEAN-CONGO; HEMORRHAGIC FEVER, CRIMEAN; HUMANS; LEUCINE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 84954133807     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.667436     Document Type: Article

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