-
1
-
-
84952641196
-
Interpreting the language of histone and DNA modifications
-
Rothbart S.B., Strahl B.D. Interpreting the language of histone and DNA modifications. Biochim. Biophys. Acta 1839, 2014:627-643.
-
(1839)
Biochim. Biophys. Acta
, vol.2014
, pp. 627-643
-
-
Rothbart, S.B.1
Strahl, B.D.2
-
2
-
-
33744792310
-
Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
-
Rosenfeld M.G., Lunyak V.V., Glass C.K. Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev. 2006, 20:1405-1428.
-
(2006)
Genes Dev.
, vol.20
, pp. 1405-1428
-
-
Rosenfeld, M.G.1
Lunyak, V.V.2
Glass, C.K.3
-
3
-
-
30544442161
-
Histone acetylation increases chromatin accessibility
-
Gorisch S.M., Wachsmuth M., Toth K.F., Lichter P., Rippe K. Histone acetylation increases chromatin accessibility. J. Cell Sci. 2005, 118:5825-5834.
-
(2005)
J. Cell Sci.
, vol.118
, pp. 5825-5834
-
-
Gorisch, S.M.1
Wachsmuth, M.2
Toth, K.F.3
Lichter, P.4
Rippe, K.5
-
4
-
-
77956497337
-
Genome-wide assessment of differential roles for p300 and CBP in transcription regulation
-
Ramos Y.F., Hestand M.S., Verlaan M., Krabbendam E., Ariyurek Y., van Galen M., et al. Genome-wide assessment of differential roles for p300 and CBP in transcription regulation. Nucleic Acids Res. 2010, 38:5396-5408.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 5396-5408
-
-
Ramos, Y.F.1
Hestand, M.S.2
Verlaan, M.3
Krabbendam, E.4
Ariyurek, Y.5
van Galen, M.6
-
5
-
-
50049108874
-
Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma
-
Marquard L., Gjerdrum L.M., Christensen I.J., Jensen P.B., Sehested M., Ralfkiaer E. Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma. Histopathology 2008, 53:267-277.
-
(2008)
Histopathology
, vol.53
, pp. 267-277
-
-
Marquard, L.1
Gjerdrum, L.M.2
Christensen, I.J.3
Jensen, P.B.4
Sehested, M.5
Ralfkiaer, E.6
-
6
-
-
20144388146
-
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
-
Fraga M.F., Ballestar E., Villar-Garea A., Boix-Chornet M., Espada J., Schotta G., et al. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat. Genet. 2005, 37:391-400.
-
(2005)
Nat. Genet.
, vol.37
, pp. 391-400
-
-
Fraga, M.F.1
Ballestar, E.2
Villar-Garea, A.3
Boix-Chornet, M.4
Espada, J.5
Schotta, G.6
-
7
-
-
33845996135
-
Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)
-
Duvic M., Talpur R., Ni X., Zhang C., Hazarika P., Kelly C., et al. Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL). Blood 2007, 109:31-39.
-
(2007)
Blood
, vol.109
, pp. 31-39
-
-
Duvic, M.1
Talpur, R.2
Ni, X.3
Zhang, C.4
Hazarika, P.5
Kelly, C.6
-
8
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A., Cuddapah S., Cui K., Roh T.Y., Schones D.E., Wang Z., et al. High-resolution profiling of histone methylations in the human genome. Cell 2007, 129:823-837.
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.Y.4
Schones, D.E.5
Wang, Z.6
-
9
-
-
35348986412
-
Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation
-
Kirmizis A., Santos-Rosa H., Penkett C.J., Singer M.A., Vermeulen M., Mann M., et al. Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation. Nature 2007, 449:928-932.
-
(2007)
Nature
, vol.449
, pp. 928-932
-
-
Kirmizis, A.1
Santos-Rosa, H.2
Penkett, C.J.3
Singer, M.A.4
Vermeulen, M.5
Mann, M.6
-
10
-
-
37249026306
-
PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation
-
Hyllus D., Stein C., Schnabel K., Schiltz E., Imhof A., Dou Y., et al. PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation. Genes Dev. 2007, 21:3369-3380.
-
(2007)
Genes Dev.
, vol.21
, pp. 3369-3380
-
-
Hyllus, D.1
Stein, C.2
Schnabel, K.3
Schiltz, E.4
Imhof, A.5
Dou, Y.6
-
11
-
-
41249088464
-
Arginine methylation of the histone H3 tail impedes effector binding
-
Iberg A.N., Espejo A., Cheng D., Kim D., Michaud-Levesque J., Richard S., et al. Arginine methylation of the histone H3 tail impedes effector binding. J. Biol. Chem. 2008, 283:3006-3010.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 3006-3010
-
-
Iberg, A.N.1
Espejo, A.2
Cheng, D.3
Kim, D.4
Michaud-Levesque, J.5
Richard, S.6
-
13
-
-
79958013243
-
Histone H4 acetylation differentially modulates arginine methylation by an in Cis mechanism
-
Feng Y., Wang J., Asher S., Hoang L., Guardiani C., Ivanov I., et al. Histone H4 acetylation differentially modulates arginine methylation by an in Cis mechanism. J. Biol. Chem. 2011, 286:20323-20334.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 20323-20334
-
-
Feng, Y.1
Wang, J.2
Asher, S.3
Hoang, L.4
Guardiani, C.5
Ivanov, I.6
-
15
-
-
35548934558
-
MLL translocations, histone modifications and leukaemia stem-cell development
-
Krivtsov A.V., Armstrong S.A. MLL translocations, histone modifications and leukaemia stem-cell development. Nat. Rev. Cancer 2007, 7:823-833.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 823-833
-
-
Krivtsov, A.V.1
Armstrong, S.A.2
-
16
-
-
17444375685
-
HDOT1L links histone methylation to leukemogenesis
-
Okada Y., Feng Q., Lin Y., Jiang Q., Li Y., Coffield V.M., et al. hDOT1L links histone methylation to leukemogenesis. Cell 2005, 121:167-178.
-
(2005)
Cell
, vol.121
, pp. 167-178
-
-
Okada, Y.1
Feng, Q.2
Lin, Y.3
Jiang, Q.4
Li, Y.5
Coffield, V.M.6
-
17
-
-
77954475631
-
The role of histone deacetylase inhibitors in the treatment of patients with cutaneous T-cell lymphoma
-
Hymes K.B. The role of histone deacetylase inhibitors in the treatment of patients with cutaneous T-cell lymphoma. Clin. Lymphoma Myeloma Leuk. 2010, 10:98-109.
-
(2010)
Clin. Lymphoma Myeloma Leuk.
, vol.10
, pp. 98-109
-
-
Hymes, K.B.1
-
18
-
-
84859149166
-
Genes are often sheltered from the global histone hyperacetylation induced by HDAC inhibitors
-
Halsall J., Gupta V., O'Neill L.P., Turner B.M., Nightingale K.P. Genes are often sheltered from the global histone hyperacetylation induced by HDAC inhibitors. PLoS One 2012, 7.
-
(2012)
PLoS One
, vol.7
-
-
Halsall, J.1
Gupta, V.2
O'Neill, L.P.3
Turner, B.M.4
Nightingale, K.P.5
-
19
-
-
34249993174
-
SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor bortezomib
-
Emanuele S., Lauricella M., Carlisi D., Vassallo B., D'Anneo A., Di Fazio P., et al. SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor bortezomib. Apoptosis 2007, 12:1327-1338.
-
(2007)
Apoptosis
, vol.12
, pp. 1327-1338
-
-
Emanuele, S.1
Lauricella, M.2
Carlisi, D.3
Vassallo, B.4
D'Anneo, A.5
Di Fazio, P.6
-
20
-
-
84875669092
-
Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylation
-
Kennedy P.J., Feng J., Robison A.J., Maze I., Badimon A., Mouzon E., et al. Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylation. Nat. Neurosci. 2013, 16:434-440.
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 434-440
-
-
Kennedy, P.J.1
Feng, J.2
Robison, A.J.3
Maze, I.4
Badimon, A.5
Mouzon, E.6
-
21
-
-
33947492804
-
Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation
-
Nightingale K.P., Gendreizig S., White D.A., Bradbury C., Hollfelder F., Turner B.M. Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation. J. Biol. Chem. 2007, 282:4408-4416.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 4408-4416
-
-
Nightingale, K.P.1
Gendreizig, S.2
White, D.A.3
Bradbury, C.4
Hollfelder, F.5
Turner, B.M.6
-
22
-
-
78651289082
-
Histone deacetylase inhibitors stimulate histone H3 lysine 4 methylation in part via transcriptional repression of histone H3 lysine 4 demethylases
-
Huang P.H., Chen C.H., Chou C.C., Sargeant A.M., Kulp S.K., Teng C.M., et al. Histone deacetylase inhibitors stimulate histone H3 lysine 4 methylation in part via transcriptional repression of histone H3 lysine 4 demethylases. Mol. Pharmacol. 2011, 79:197-206.
-
(2011)
Mol. Pharmacol.
, vol.79
, pp. 197-206
-
-
Huang, P.H.1
Chen, C.H.2
Chou, C.C.3
Sargeant, A.M.4
Kulp, S.K.5
Teng, C.M.6
-
23
-
-
79960058024
-
Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor
-
Daigle S.R., Olhava E.J., Therkelsen C.A., Majer C.R., Sneeringer C.J., Song J., et al. Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor. Cancer Cell 2011, 20:53-65.
-
(2011)
Cancer Cell
, vol.20
, pp. 53-65
-
-
Daigle, S.R.1
Olhava, E.J.2
Therkelsen, C.A.3
Majer, C.R.4
Sneeringer, C.J.5
Song, J.6
-
24
-
-
84873668916
-
MS(3) fragmentation patterns of monomethylarginine species and the quantification of all methylarginine species in yeast using MRM(3)
-
Lakowski T.M., Szeitz A., Pak M.L., Thomas D., Vhuiyan M.I., Kotthaus J., et al. MS(3) fragmentation patterns of monomethylarginine species and the quantification of all methylarginine species in yeast using MRM(3). J. Proteome 2013, 80:43-54.
-
(2013)
J. Proteome
, vol.80
, pp. 43-54
-
-
Lakowski, T.M.1
Szeitz, A.2
Pak, M.L.3
Thomas, D.4
Vhuiyan, M.I.5
Kotthaus, J.6
-
25
-
-
67650882496
-
Kinetic analysis of human protein arginine N-methyltransferase 2: formation of monomethyl- and asymmetric dimethyl-arginine residues on histone H4
-
Lakowski T.M., Frankel A. Kinetic analysis of human protein arginine N-methyltransferase 2: formation of monomethyl- and asymmetric dimethyl-arginine residues on histone H4. Biochem. J. 2009, 421:253-261.
-
(2009)
Biochem. J.
, vol.421
, pp. 253-261
-
-
Lakowski, T.M.1
Frankel, A.2
-
26
-
-
84867007812
-
Analogues of the HIV-Tat peptide containing Nη-modified arginines as potent inhibitors of protein arginine N-methyltransferases
-
'tHart P., Thomas D., van Ommeren R., Lakowski T.M., Frankel A., Martin N.I. Analogues of the HIV-Tat peptide containing Nη-modified arginines as potent inhibitors of protein arginine N-methyltransferases. Med. Chem. Commun. 2012, 3:1235.
-
(2012)
Med. Chem. Commun.
, vol.3
, pp. 1235
-
-
'tHart, P.1
Thomas, D.2
van Ommeren, R.3
Lakowski, T.M.4
Frankel, A.5
Martin, N.I.6
-
27
-
-
44349099853
-
A kinetic study of human protein arginine N-methyltransferase 6 reveals a distributive mechanism
-
Lakowski T.M., Frankel A. A kinetic study of human protein arginine N-methyltransferase 6 reveals a distributive mechanism. J. Biol. Chem. 2008, 283:10015-10025.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 10015-10025
-
-
Lakowski, T.M.1
Frankel, A.2
-
28
-
-
71749115867
-
Approaches to measuring the activities of protein arginine N-methyltransferases
-
Lakowski T.M., Zurita-Lopez C., Clarke S.G., Frankel A. Approaches to measuring the activities of protein arginine N-methyltransferases. Anal. Biochem. 2010, 397:1-11.
-
(2010)
Anal. Biochem.
, vol.397
, pp. 1-11
-
-
Lakowski, T.M.1
Zurita-Lopez, C.2
Clarke, S.G.3
Frankel, A.4
-
30
-
-
84922362602
-
HDAC1 and Klf4 interplay critically regulates human myeloid leukemia cell proliferation
-
Huang Y., Chen J., Lu C., Han J., Wang G., Song C., et al. HDAC1 and Klf4 interplay critically regulates human myeloid leukemia cell proliferation. Cell Death Dis. 2014, 5.
-
(2014)
Cell Death Dis.
, vol.5
-
-
Huang, Y.1
Chen, J.2
Lu, C.3
Han, J.4
Wang, G.5
Song, C.6
-
31
-
-
84874770498
-
Quantitative analysis of histone modifications: formaldehyde is a source of pathological n(6)-formyllysine that is refractory to histone deacetylases
-
Edrissi B., Taghizadeh K., Dedon P.C. Quantitative analysis of histone modifications: formaldehyde is a source of pathological n(6)-formyllysine that is refractory to histone deacetylases. PLoS Genet. 2013, 9.
-
(2013)
PLoS Genet.
, vol.9
-
-
Edrissi, B.1
Taghizadeh, K.2
Dedon, P.C.3
-
32
-
-
67650090545
-
Histone deacetylase inhibitors: potential in cancer therapy
-
Marks P.A., Xu W.S. Histone deacetylase inhibitors: potential in cancer therapy. J. Cell. Biochem. 2009, 107:600-608.
-
(2009)
J. Cell. Biochem.
, vol.107
, pp. 600-608
-
-
Marks, P.A.1
Xu, W.S.2
-
33
-
-
84902251340
-
A histone H3K36 chromatin switch coordinates DNA double-strand break repair pathway choice
-
Pai C.-C., Deegan R.S., Subramanian L., Gal C., Sarkar S., Blaikley E.J., et al. A histone H3K36 chromatin switch coordinates DNA double-strand break repair pathway choice. Nat. Commun. 2014, 5.
-
(2014)
Nat. Commun.
, vol.5
-
-
Pai, C.-C.1
Deegan, R.S.2
Subramanian, L.3
Gal, C.4
Sarkar, S.5
Blaikley, E.J.6
-
35
-
-
77957970301
-
Epigenetic modifications and human disease
-
Portela A., Esteller M. Epigenetic modifications and human disease. Nat. Biotechnol. 2010, 28:1057-1068.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 1057-1068
-
-
Portela, A.1
Esteller, M.2
-
36
-
-
79954577753
-
Histone deacetylase inhibition alters histone methylation associated with heat shock protein 70 promoter modifications in astrocytes and neurons
-
Marinova Z., Leng Y., Leeds P., Chuang D.M. Histone deacetylase inhibition alters histone methylation associated with heat shock protein 70 promoter modifications in astrocytes and neurons. Neuropharmacology 2011, 60:1109-1115.
-
(2011)
Neuropharmacology
, vol.60
, pp. 1109-1115
-
-
Marinova, Z.1
Leng, Y.2
Leeds, P.3
Chuang, D.M.4
-
37
-
-
79960031177
-
The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO
-
Duque-Afonso J., Yalcin A., Berg T., Abdelkarim M., Heidenreich O., Lubbert M. The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO. Oncogene 2011, 30:3062-3072.
-
(2011)
Oncogene
, vol.30
, pp. 3062-3072
-
-
Duque-Afonso, J.1
Yalcin, A.2
Berg, T.3
Abdelkarim, M.4
Heidenreich, O.5
Lubbert, M.6
-
38
-
-
18244383806
-
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
-
Göttlicher M., Minucci S., Zhu P., Krämer O.H., Schimpf A., Giavara S., et al. Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J. 2001, 20:6969-6978.
-
(2001)
EMBO J.
, vol.20
, pp. 6969-6978
-
-
Göttlicher, M.1
Minucci, S.2
Zhu, P.3
Krämer, O.H.4
Schimpf, A.5
Giavara, S.6
-
39
-
-
84939877149
-
HDAC inhibition through valproic acid modulates the methylation profiles in human embryonic kidney cells
-
Ganai S.A., Malli Kalladi S., Mahadevan V. HDAC inhibition through valproic acid modulates the methylation profiles in human embryonic kidney cells. J. Biomol. Struct. Dyn. 2014, 1-13.
-
(2014)
J. Biomol. Struct. Dyn.
, pp. 1-13
-
-
Ganai, S.A.1
Malli Kalladi, S.2
Mahadevan, V.3
-
40
-
-
84902919626
-
Small molecule epigenetic inhibitors targeted to histone lysine methyltransferases and demethylases
-
Wang Z., Patel D.J. Small molecule epigenetic inhibitors targeted to histone lysine methyltransferases and demethylases. Q. Rev. Biophys. 2013, 46:349-373.
-
(2013)
Q. Rev. Biophys.
, vol.46
, pp. 349-373
-
-
Wang, Z.1
Patel, D.J.2
|