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Volumn 7, Issue , 2016, Pages

Loss of Response to Anti-TNFs: Definition, Epidemiology, and Management

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; CERTOLIZUMAB PEGOL; DRUG ANTIBODY; INFLIXIMAB; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; VEDOLIZUMAB;

EID: 84953887794     PISSN: None     EISSN: 2155384X     Source Type: Journal    
DOI: 10.1038/ctg.2015.63     Document Type: Review
Times cited : (517)

References (56)
  • 1
    • 84896274307 scopus 로고    scopus 로고
    • Sustained improvement in health-related quality of life measures in patients with inflammatory bowel disease receiving prolonged anti-tumor necrosis factor therapy
    • Sherman M, Tsynman DN, Kim A et al. Sustained improvement in health-related quality of life measures in patients with inflammatory bowel disease receiving prolonged anti-tumor necrosis factor therapy. J Dig Dis 2014; 15: 174-179.
    • (2014) J Dig Dis , vol.15 , pp. 174-179
    • Sherman, M.1    Tsynman, D.N.2    Kim, A.3
  • 2
    • 84856701574 scopus 로고    scopus 로고
    • Efficacy, tolerability, and predictors of response to infliximab therapy for Crohn's disease: A large single centre experience
    • Sprakes MB, Ford AC, Warren L et al.. Efficacy, tolerability, and predictors of response to infliximab therapy for Crohn's disease: a large single centre experience. J Crohns Colitis 2012; 6: 143-153.
    • (2012) J Crohns Colitis , vol.6 , pp. 143-153
    • Sprakes, M.B.1    Ford, A.C.2    Warren, L.3
  • 3
    • 0037018761 scopus 로고    scopus 로고
    • Maintanance Infliximab for Crohn's disease: The ACCENT i randomized trial
    • ACCENT I Study group
    • Hanauer SB, Feagan BG, Lichtenstein GR et al. ACCENT I Study group. Maintanance Infliximab for Crohn's disease: the ACCENT I randomized trial. Lancet 2002; 59: 1541-1549.
    • (2002) Lancet , vol.59 , pp. 1541-1549
    • Hanauer, S.B.1    Feagan, B.G.2    Lichtenstein, G.R.3
  • 4
    • 10744221312 scopus 로고    scopus 로고
    • Infliximab maintenance therapy for fistulizing Crohn's disease
    • Sands B, Anderson FH, Bernstein CN et al. Infliximab maintenance therapy for fistulizing Crohn's disease. N Engl J Med 2004; 350: 876-885.
    • (2004) N Engl J Med , vol.350 , pp. 876-885
    • Sands, B.1    Anderson, F.H.2    Bernstein, C.N.3
  • 5
    • 79953801792 scopus 로고    scopus 로고
    • Efficacy of biological therapies in inflammatory bowel disease: Systematic review and meta-analysis
    • Ford AC, Sandborn WJ, Khan KJ et al. Efficacy of biological therapies in inflammatory bowel disease: systematic review and meta-analysis. Am J Gastroenterol 2011; 106: 644-659.
    • (2011) Am J Gastroenterol , vol.106 , pp. 644-659
    • Ford, A.C.1    Sandborn, W.J.2    Khan, K.J.3
  • 6
    • 84886946831 scopus 로고    scopus 로고
    • Optimizing anti-TNF treatments in inflammatory bowel disease
    • Ben-Hori S, Kopylov U, Chowers Y. Optimizing anti-TNF treatments in inflammatory bowel disease. Autoimmun Rev 2014; 13: 24-30.
    • (2014) Autoimmun Rev , vol.13 , pp. 24-30
    • Ben-Hori, S.1    Kopylov, U.2    Chowers, Y.3
  • 7
    • 41849135759 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease
    • Ainsworth MA, Bendtzen K, Brynskov J. Tumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease. Am J Gastroenterol 2008; 103: 944-948.
    • (2008) Am J Gastroenterol , vol.103 , pp. 944-948
    • Ma, A.1    Bendtzen, K.2    Brynskov, J.3
  • 8
    • 77957309991 scopus 로고    scopus 로고
    • Report of the ECCO pathogenesis workshop on anti-TNF therapy failures in inflammatory bowel diseases: Definitions, frequency and pharmacological aspects
    • Allez M, Karmiris K, Louis E et al. Report of the ECCO pathogenesis workshop on anti-TNF therapy failures in inflammatory bowel diseases: definitions, frequency and pharmacological aspects. J Crohns Colitis 2010; 4: 355-366.
    • (2010) J Crohns Colitis , vol.4 , pp. 355-366
    • Allez, M.1    Karmiris, K.2    Louis, E.3
  • 9
    • 84906569062 scopus 로고    scopus 로고
    • Effects of vedolizumab induction therapy for patients with Crohn's disease in whom tumor necrosis factor antagonist treatment failed
    • Sands BE, Feagan BG, Rutgeerts P et al. Effects of vedolizumab induction therapy for patients with Crohn's disease in whom tumor necrosis factor antagonist treatment failed. Gastroenterology 2014; 147: 618-627.
    • (2014) Gastroenterology , vol.147 , pp. 618-627
    • Sands, B.E.1    Feagan, B.G.2    Rutgeerts, P.3
  • 10
    • 32044451548 scopus 로고    scopus 로고
    • Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: The CLASSIC-I trial
    • Hanauer SB, Sandborn WJ, Rutgeerts P et al. Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. Gastroenterology 2006; 130: 323-333.
    • (2006) Gastroenterology , vol.130 , pp. 323-333
    • Hanauer, S.B.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 11
    • 84856163835 scopus 로고    scopus 로고
    • Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis
    • Sandborn WJ, van Assche G, Reinisch W et al. Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis. Gastroenterology 2012; 142: 257-265.
    • (2012) Gastroenterology , vol.142 , pp. 257-265
    • Sandborn, W.J.1    Van Assche, G.2    Reinisch, W.3
  • 12
    • 84913534923 scopus 로고    scopus 로고
    • Association between serum concentration of infliximab and efficacy in adult patients with ulcerative colitis
    • Adedokun OJ, Sandborn WJ, Feagan BG et al. Association between serum concentration of infliximab and efficacy in adult patients with ulcerative colitis. Gastroenterology 2014; 147: 1296-1307.
    • (2014) Gastroenterology , vol.147 , pp. 1296-1307
    • Adedokun, O.J.1    Sandborn, W.J.2    Feagan, B.G.3
  • 13
    • 28844473957 scopus 로고    scopus 로고
    • Infliximab for induction and maintenance therapy for ulcerative colitis
    • Rutgeerts P, Sandborn WJ, Feagan BG et al. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med 2005; 353: 2462-2476.
    • (2005) N Engl J Med , vol.353 , pp. 2462-2476
    • Rutgeerts, P.1    Sandborn, W.J.2    Feagan, B.G.3
  • 14
    • 84920545592 scopus 로고    scopus 로고
    • Biologics in the management of ulcerative colitis-comparative safety and efficacy of TNF- antagonists
    • Fausel R, Afzali A. Biologics in the management of ulcerative colitis-comparative safety and efficacy of TNF- antagonists. Ther Clin Risk Manag 2015; 11: 63-73.
    • (2015) Ther Clin Risk Manag , vol.11 , pp. 63-73
    • Fausel, R.1    Afzali, A.2
  • 15
    • 62049083383 scopus 로고    scopus 로고
    • Loss of response and requirement of infliximab dose intensification in Crohn's disease: A review
    • Gisbert JP, Panes J. Loss of response and requirement of infliximab dose intensification in Crohn's disease: a review. Am J Gastroenterol 2009; 104: 760-767.
    • (2009) Am J Gastroenterol , vol.104 , pp. 760-767
    • Gisbert, J.P.1    Panes, J.2
  • 16
    • 79751472562 scopus 로고    scopus 로고
    • The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: When to start, when to stop which drug to choose, and how to predict response
    • D'Haens GR, Panaccione R, Higgins PD et al. The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response Am J Gastroenterol 2011; 106: 199-212.
    • (2011) Am J Gastroenterol , vol.106 , pp. 199-212
    • D'Haens, G.R.1    Panaccione, R.2    Higgins, P.D.3
  • 17
    • 79953688705 scopus 로고    scopus 로고
    • Loss of response to anti-TNF treatments in Crohn's disease
    • Ben-Horin S, Chowers Y. Loss of response to anti-TNF treatments in Crohn's disease. Aliment Pharmacol Ther 2011; 33: 987-995.
    • (2011) Aliment Pharmacol Ther , vol.33 , pp. 987-995
    • Ben-Horin, S.1    Chowers, Y.2
  • 18
    • 79953786419 scopus 로고    scopus 로고
    • Loss of response and need for adalimumab dose intensification in Crohn's disease. A systematic review
    • Billioud V, Sandborn WJ, Peyrin-Biroulet L. Loss of response and need for adalimumab dose intensification in Crohn's disease. A systematic review. Am J Gastroenterol 2011; 106: 674-684.
    • (2011) Am J Gastroenterol , vol.106 , pp. 674-684
    • Billioud, V.1    Sandborn, W.J.2    Peyrin-Biroulet, L.3
  • 19
    • 84903470906 scopus 로고    scopus 로고
    • Loss of response to anti-tumor necrosis factors: What is the next step
    • Ben-Horin S. Loss of response to anti-tumor necrosis factors: What is the next step Dig Dis 2014; 32: 384-388.
    • (2014) Dig Dis , vol.32 , pp. 384-388
    • Ben-Horin, S.1
  • 20
    • 33846242958 scopus 로고    scopus 로고
    • Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: The CHARM trial
    • Colombel JF, Sandborn WJ, Rutgeerts P et al. Adalimumab for maintenance of clinical response and remission in patients with crohn's disease: The CHARM trial. Gastroenterology 2007; 132: 52-65.
    • (2007) Gastroenterology , vol.132 , pp. 52-65
    • Colombel, J.F.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 21
    • 0033529049 scopus 로고    scopus 로고
    • Infliximab for the treatment of fistula s in patients with Crohn's disease
    • Present DH, Rutgeerts P, Targan S et al. Infliximab for the treatment of fistula s in patients with Crohn's disease. N Engl J Med 1999; 340: 1398-1405.
    • (1999) N Engl J Med , vol.340 , pp. 1398-1405
    • Present, D.H.1    Rutgeerts, P.2    Targan, S.3
  • 23
    • 84862338286 scopus 로고    scopus 로고
    • Doubling the infliximab dose versus halving the infusion intervals in Crohn's disease patients with loss of response
    • Katz L, Taylor RP, Cunningham MR et al. Doubling the infliximab dose versus halving the infusion intervals in Crohn's disease patients with loss of response. Inflamm Bowel Dis 2012; 18: 2026-2033.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 2026-2033
    • Katz, L.1    Taylor, R.P.2    Cunningham, M.R.3
  • 24
    • 20944434562 scopus 로고    scopus 로고
    • Formation, distribution, and elimination of infliximab and anti-infliximab immune complexes in cynomolugus monkeys
    • Rojas JT, Taylor RP, Cunningham MR et al. Formation, distribution, and elimination of infliximab and anti-infliximab immune complexes in cynomolugus monkeys. J Pharmacol Exp Ther 2005;313:578-585.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 578-585
    • Rojas, J.T.1    Taylor, R.P.2    Cunningham, M.R.3
  • 25
    • 84905496301 scopus 로고    scopus 로고
    • Pharmacokinetics of adalimumab in inflammatory bowel Diseases: A systematic review and meta-analysis
    • Paul S, Moreau AC, Del Tedesco E et al. Pharmacokinetics of adalimumab in inflammatory bowel diseases: a systematic review and meta-analysis. Inflamm Bowel Dis 2014; 20: 1288-1295.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 1288-1295
    • Paul, S.1    Moreau, A.C.2    Del Tedesco, E.3
  • 26
    • 84890219983 scopus 로고    scopus 로고
    • Association between pharmacokinetics of adalimumab and mucosal healing in patients with inflammatory bowel diseases
    • Roblin X, Marotte H, Rinaudo M et al. Association between pharmacokinetics of adalimumab and mucosal healing in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol 2014; 12: 80-84.
    • (2014) Clin Gastroenterol Hepatol , vol.12 , pp. 80-84
    • Roblin, X.1    Marotte, H.2    Rinaudo, M.3
  • 27
    • 84906236434 scopus 로고    scopus 로고
    • Adalimumab drug and antibody levels as predictors of clinical and laboratory response in patients with Crohn's disease
    • Mazor Y, Almog R, Kopylov U et al. Adalimumab drug and antibody levels as predictors of clinical and laboratory response in patients with Crohn's disease. Aliment Pharmacol Ther 2014; 40: 620-628.
    • (2014) Aliment Pharmacol Ther , vol.40 , pp. 620-628
    • Mazor, Y.1    Almog, R.2    Kopylov, U.3
  • 28
    • 53549083244 scopus 로고    scopus 로고
    • Immunogenicity negatively influences the outcome of adalimumab treatment in Crohn's disease
    • West RL, Zelinkova Z, Wolbink GJ et al. Immunogenicity negatively influences the outcome of adalimumab treatment in Crohn's disease. Aliment Pharmacol Ther 2008; 28: 1122-1126.
    • (2008) Aliment Pharmacol Ther , vol.28 , pp. 1122-1126
    • West, R.L.1    Zelinkova, Z.2    Wolbink, G.J.3
  • 29
    • 78650149614 scopus 로고    scopus 로고
    • Adherence to adalimumab therapy in Crohn's disease: A French multicenter experience
    • Billioud V, Laharie D, Filippi J et al. Adherence to adalimumab therapy in Crohn's disease: a French multicenter experience. Inflamm Bowel Dis 2011; 17: 152-159.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 152-159
    • Billioud, V.1    Laharie, D.2    Filippi, J.3
  • 30
    • 84879117728 scopus 로고    scopus 로고
    • Adherence to anti-TNF therapy in inflammatory bowel Diseases: A systematic review
    • Lopez A, Billioud V, Peyrin-Biroulet C et al. Adherence to anti-TNF therapy in inflammatory bowel diseases: a systematic review. Inflamm Bowel Dis 2013; 19: 1528-1533.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 1528-1533
    • Lopez, A.1    Billioud, V.2    Peyrin-Biroulet, C.3
  • 31
    • 77951974444 scopus 로고    scopus 로고
    • Clinical utility of measuring infliximab and human antichimeric antibody concentrations in patients with inflammatory bowel disease
    • Afif W, Loftus EV Jr, Faubion WA et al. Clinical utility of measuring infliximab and human antichimeric antibody concentrations in patients with inflammatory bowel disease. Am J Gastroenterol 2010; 105: 1133-1139.
    • (2010) Am J Gastroenterol , vol.105 , pp. 1133-1139
    • Afif, W.1    Loftus, E.V.2    Faubion, W.A.3
  • 32
    • 84925367939 scopus 로고    scopus 로고
    • Levels of drug and antidrug antibodies are associated with outcome of interventions after loss of response to infliximab or adalimumab
    • Yanai H, Lichtenstein L, Assa A et al. Levels of drug and antidrug antibodies are associated with outcome of interventions after loss of response to infliximab or adalimumab. Clin Gastroenterol Hepatol 2015; 13: 522-530.
    • (2015) Clin Gastroenterol Hepatol , vol.13 , pp. 522-530
    • Yanai, H.1    Lichtenstein, L.2    Assa, A.3
  • 33
    • 84905587709 scopus 로고    scopus 로고
    • Development of an algorithm incorporating pharmacokinetics of adalimumab in inflammatory bowel diseases
    • Roblin X, Rinaudo M, Del Tedesco E et al. Development of an algorithm incorporating pharmacokinetics of adalimumab in inflammatory bowel diseases. Am J Gastroenterol 2014; 109: 1250-1256.
    • (2014) Am J Gastroenterol , vol.109 , pp. 1250-1256
    • Roblin, X.1    Rinaudo, M.2    Del Tedesco, E.3
  • 34
    • 78651237721 scopus 로고    scopus 로고
    • The immunogenic part of infliximab is the F(ab')2, but measuring antibodies to the intact infliximab molecule is more clinically useful
    • Ben-Horin S, Yavzori M, Katz L et al. The immunogenic part of infliximab is the F(ab')2, but measuring antibodies to the intact infliximab molecule is more clinically useful. Gut 2011; 60: 41-48.
    • (2011) Gut , vol.60 , pp. 41-48
    • Ben-Horin, S.1    Yavzori, M.2    Katz, L.3
  • 35
    • 0036269445 scopus 로고    scopus 로고
    • The relationship of serum infliximab concentrations to clinical improvement in rheumatoid arthritis: Results from ATTRACT, a multicenter, randomized, double-blind, placebo-controlled trial
    • St Clair EW, Wagner CL, Fasanmade AA et al. The relationship of serum infliximab concentrations to clinical improvement in rheumatoid arthritis: results from ATTRACT, a multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2002; 46: 1451-1459.
    • (2002) Arthritis Rheum , vol.46 , pp. 1451-1459
    • St Clair, E.W.1    Wagner, C.L.2    Fasanmade, A.A.3
  • 36
    • 84893691878 scopus 로고    scopus 로고
    • Dose optimization is effective in ulcerative colitis patients losing response to infliximab: A collaborative multicentre retrospective study
    • Cesarini M, Katsanos K, Papamichael K et al. Dose optimization is effective in ulcerative colitis patients losing response to infliximab: a collaborative multicentre retrospective study. Dig Liver Dis 2014; 46: 135-139.
    • (2014) Dig Liver Dis , vol.46 , pp. 135-139
    • Cesarini, M.1    Katsanos, K.2    Papamichael, K.3
  • 37
    • 84893689945 scopus 로고    scopus 로고
    • Dose optimization of infliximab in patients with rheumatoid arthritis
    • Alten R, van den Bosc F. Dose optimization of infliximab in patients with rheumatoid arthritis. Int J Rheum Dis 2014; 17: 5-18.
    • (2014) Int J Rheum Dis , vol.17 , pp. 5-18
    • Alten, R.1    Vanden Bosc, F.2
  • 38
    • 84878945732 scopus 로고    scopus 로고
    • Antibody Response to Infliximab and its impact on Pharmacokinetics can be transient
    • Casteele N, Gils A, Singh S et al. Antibody Response to Infliximab and its impact on Pharmacokinetics can be transient. Am J of Gastroenterol 2013; 108: 962-971.
    • (2013) Am J of Gastroenterol , vol.108 , pp. 962-971
    • Casteele, N.1    Gils, A.2    Singh, S.3
  • 39
    • 34249281002 scopus 로고    scopus 로고
    • Adalimumab for maintenance treatment of Crohn's disease: Results of the CLASSIC II trial
    • Sandborn WJ, Hanauer SB, Rutgeerts P et al. Adalimumab for maintenance treatment of Crohn's disease: results of the CLASSIC II trial. Gut 2007; 56: 1232-1239.
    • (2007) Gut , vol.56 , pp. 1232-1239
    • Sandborn, W.J.1    Hanauer, S.B.2    Rutgeerts, P.3
  • 40
    • 0037434552 scopus 로고    scopus 로고
    • Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease
    • Baert F, Noman M, Vermeire S et al. Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease. N Engl J Med 2003; 348: 601-608.
    • (2003) N Engl J Med , vol.348 , pp. 601-608
    • Baert, F.1    Noman, M.2    Vermeire, S.3
  • 41
    • 3042579454 scopus 로고    scopus 로고
    • Incidence and importance of antibody responses to infliximab after maintenance or episodic treatment in Crohn's disease
    • Hanauer SB, Wagner CL, Bala M et al. Incidence and importance of antibody responses to infliximab after maintenance or episodic treatment in Crohn's disease. Clin Gastroenterol Hepatol 2004; 2: 542-553.
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 542-553
    • Hanauer, S.B.1    Wagner, C.L.2    Bala, M.3
  • 42
    • 84875371134 scopus 로고    scopus 로고
    • Addition of an immunomodulator to infliximab therapy eliminates antidrug antibodies in serum and restores clinical response of patients with inflammatory bowel disease
    • Ben-Horin S, Waterman M, Kopylov U et al. Addition of an immunomodulator to infliximab therapy eliminates antidrug antibodies in serum and restores clinical response of patients with inflammatory bowel disease. Clin Gastroenterol Hepatol 2013; 11: 444.
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 444
    • Ben-Horin, S.1    Waterman, M.2    Kopylov, U.3
  • 43
    • 84897629643 scopus 로고    scopus 로고
    • Addition of thiopurines can recapture response in patients with Crohn's disease who have lost response to anti-tumor necrosis factor monotherapy
    • Ong DE, Kamm MA, Hartono JL et al. Addition of thiopurines can recapture response in patients with Crohn's disease who have lost response to anti-tumor necrosis factor monotherapy. Gastroenterol Hepatol 2013; 28: 1595-1599.
    • (2013) Gastroenterol Hepatol , vol.28 , pp. 1595-1599
    • Ong, D.E.1    Ma, K.2    Hartono, J.L.3
  • 44
    • 84928628450 scopus 로고    scopus 로고
    • Concentrations of 6-thioguanine nucleotide correlate with trough levels of infliximab in patients with inflammatory bowel disease on combination therapy
    • Yarur A, Kubiliun M, Czul F et al. Concentrations of 6-thioguanine nucleotide correlate with trough levels of infliximab in patients with inflammatory bowel disease on combination therapy. Clin Gastroenterol Hepatol 2015; 13: 1118-1124.
    • (2015) Clin Gastroenterol Hepatol , vol.13 , pp. 1118-1124
    • Yarur, A.1    Kubiliun, M.2    Czul, F.3
  • 45
    • 84892979466 scopus 로고    scopus 로고
    • Postinduction serum infliximab trough level and decrease of C-reactive protein level are associated with durable sustained response to infliximab: A retrospective analysis of the ACCENT i trial
    • Cornillie F, Hanauer SB, Diamond RH et al. Postinduction serum infliximab trough level and decrease of C-reactive protein level are associated with durable sustained response to infliximab: a retrospective analysis of the ACCENT I trial. Gut 2014; 63: 1721-1727.
    • (2014) Gut , vol.63 , pp. 1721-1727
    • Cornillie, F.1    Hanauer, S.B.2    Diamond, R.H.3
  • 46
    • 44649090092 scopus 로고    scopus 로고
    • Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: A randomized trial
    • Van Assche G, Magdelaine-Beuzelin C, D'Haens G et al. Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: a randomized trial. Gastroenterology 2008; 134: 1861-1868.
    • (2008) Gastroenterology , vol.134 , pp. 1861-1868
    • Van Assche, G.1    Magdelaine-Beuzelin, C.2    D'Haens, G.3
  • 47
    • 77956997278 scopus 로고    scopus 로고
    • Usefulness of co-treatment with immunomodulators in patients with inflammatory bowel disease treated with scheduled infliximab maintenance therapy
    • Sokol H, Seksik P, Carrat F et al. Usefulness of co-treatment with immunomodulators in patients with inflammatory bowel disease treated with scheduled infliximab maintenance therapy. Gut 2010; 59: 1363-1368.
    • (2010) Gut , vol.59 , pp. 1363-1368
    • Sokol, H.1    Seksik, P.2    Carrat, F.3
  • 48
    • 84900000652 scopus 로고    scopus 로고
    • Systematic review: The use of thiopurines or anti-TNF in post-operative Crohn's disease maintenance-progress and prospects
    • Jones GR, Kennedy NA, Lees CW et al. Systematic review: the use of thiopurines or anti-TNF in post-operative Crohn's disease maintenance-progress and prospects. Aliment Pharmacol Ther 2014; 39: 1253-1265.
    • (2014) Aliment Pharmacol Ther , vol.39 , pp. 1253-1265
    • Jones, G.R.1    Kennedy, N.A.2    Lees, C.W.3
  • 49
    • 84855648247 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of biologics for inflammatory bowel disease
    • Colombel JF, Feagan BG, Sandborn WJ et al. Therapeutic drug monitoring of biologics for inflammatory bowel disease. Inflamm Bowel Dis 2012; 18: 349-358.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 349-358
    • Colombel, J.F.1    Feagan, B.G.2    Sandborn, W.J.3
  • 50
    • 84939563618 scopus 로고    scopus 로고
    • Preemptive dose optimization using therapeutic drug monitoring for biologic therapy of Crohn's disease: Avoiding failure while lowering costs
    • Vande Casteele N, Ann Gils. Preemptive dose optimization using therapeutic drug monitoring for biologic therapy of crohn's disease: avoiding failure while lowering costs Dig Dis Sci 2015; 60: 2571-2573.
    • (2015) Dig Dis Sci , vol.60 , pp. 2571-2573
    • Vande, C.N.1    Gils, A.2
  • 51
    • 0037379792 scopus 로고    scopus 로고
    • Intravenous hydrocortisone premedication reduces antibodies to infliximab in Crohn's disease: A randomized controlled trial
    • Farrell RJ, Alsahli M, Jeen YT et al. Intravenous hydrocortisone premedication reduces antibodies to infliximab in Crohn's disease: a randomized controlled trial. Gastroenterology 2003; 124: 917-924.
    • (2003) Gastroenterology , vol.124 , pp. 917-924
    • Farrell, R.J.1    Alsahli, M.2    Jeen, Y.T.3
  • 52
    • 2442560241 scopus 로고    scopus 로고
    • Optimizing anti-TNF treatment in inflammatory bowel disease
    • Rutgeerts P, Van Assche G, Vermeire S. Optimizing anti-TNF treatment in inflammatory bowel disease. Gastroenterology 2004; 126: 1593-1610.
    • (2004) Gastroenterology , vol.126 , pp. 1593-1610
    • Rutgeerts, P.1    Van Assche, G.2    Vermeire, S.3
  • 53
    • 0032055981 scopus 로고    scopus 로고
    • Overexpression of the p80 TNF receptor leads to TNF-dependent apoptosis, nuclear factor-kappa B activation, and c-Jun kinase activation
    • Haridas V, Darnay BG, Natarajan K et al. Overexpression of the p80 TNF receptor leads to TNF-dependent apoptosis, nuclear factor-kappa B activation, and c-Jun kinase activation. J Immunol 1998; 160: 3152-3162.
    • (1998) J Immunol , vol.160 , pp. 3152-3162
    • Haridas, V.1    Darnay, B.G.2    Natarajan, K.3
  • 54
    • 0027301244 scopus 로고
    • Ligand passing: The 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor
    • Tartaglia LA, Pennica D, Goeddel DV. Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor. J Biol Chem 1993; 268: 18542-18548.
    • (1993) J Biol Chem , vol.268 , pp. 18542-18548
    • Tartaglia, L.A.1    Pennica, D.2    Goeddel, D.V.3
  • 55
    • 0033152828 scopus 로고    scopus 로고
    • Induction of cell death by tumour necrosis factor (TNF) receptor 2 CD40 and CD30: A role for TNF-R1 activation by endogenous membraneanchored TNF
    • Grell M, Zimmermann G, Gottfried E et al. Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membraneanchored TNF. EMBO J 1999; 18: 3034-3043.
    • (1999) EMBO J , vol.18 , pp. 3034-3043
    • Grell, M.1    Zimmermann, G.2    Gottfried, E.3
  • 56
    • 0028866022 scopus 로고
    • The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor
    • Grell M, Douni E, Wajant H et al. The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor. Cell 1995; 83: 793-802.
    • (1995) Cell , vol.83 , pp. 793-802
    • Grell, M.1    Douni, E.2    Wajant, H.3


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