The joint subclinical elevation of CRP and IL-6 is associated with lower health-related quality of life in comparison with no elevation or elevation of only one of the biomarkers

Quality of Life Research

Volumn 25, Issue 1, 2016, Pages 213-221

  Garvin, Peter ^a,b   Nilsson, Evalill ^a,b   Ernerudh, Jan ^b   Kristenson, Margareta ^b  

^a Unit of Research and Development in Local Health Care FoU enheten för Närsjukvården i Östegötland   (Sweden)

^b LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Biomarkers; CRP; Health related quality of life; Inflammation; Interleukin; Population; SF 36

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; INTERLEUKIN 6; IL6 PROTEIN, HUMAN;

ADULT; AGE; AGED; ARTICLE; CORRELATION ANALYSIS; FEMALE; HUMAN; INFLAMMATION; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; MENTAL HEALTH; MIDDLE AGED; PSYCHOLOGICAL ASPECT; QUALITY OF LIFE; REGRESSION ANALYSIS; SEX; SHORT FORM 36; BLOOD; CAUCASIAN; HEALTH STATUS; PSYCHOLOGY; QUESTIONNAIRE;

AGED; BIOMARKERS; C-REACTIVE PROTEIN; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HEALTH STATUS; HUMANS; INFLAMMATION; INTERLEUKIN-6; LIFE STYLE; MALE; MENTAL HEALTH; MIDDLE AGED; QUALITY OF LIFE; SURVEYS AND QUESTIONNAIRES;

EID: 84953837776     PISSN: 09629343     EISSN: 15732649     Source Type: Journal    
DOI: 10.1007/s11136-015-1068-6     Document Type: Article

References (41)

1. Ware, J. E. Jr., & Sherbourne, C. D. (1992). The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Medical Care,30(6), 473–483.
2. Otero-Rodriguez, A., Leon-Munoz, L. M., Balboa-Castillo, T., Banegas, J. R., Rodriguez-Artalejo, F., & Guallar-Castillon, P. (2010). Change in health-related quality of life as a predictor of mortality in the older adults. Quality of Life Research,19(1), 15–23.
3. Sadetsky, N., Hubbard, A., Carroll, P. R., & Satariano, W. (2009). Predictive value of serial measurements of quality of life on all-cause mortality in prostate cancer patients: Data from CaPSURE (cancer of the prostate strategic urologic research endeavor) database. Quality of Life Research,18(8), 1019–1027.
4. Tsai, S. Y., Chi, L. Y., Lee, C. H., & Chou, P. (2007). Health-related quality of life as a predictor of mortality among community-dwelling older persons. European Journal of Epidemiology,22(1), 19–26.
5. Nilsson, E., & Kristenson, M. (2010). Psychological factors related to physical, social, and mental dimensions of the SF-36: A population-based study of middle-aged women and men. Patient Related Outcome Measures,1, 153–162.
6. Irwin, M. R. (2008). Human psychoneuroimmunology: 20 years of discovery. Brain, Behavior, and Immunity,22(2), 129–139.
7. Everson-Rose, S. A., & Lewis, T. T. (2005). Psychosocial factors and cardiovascular diseases. Annual Review of Public Health,26, 469–500.
8. Steptoe, A., Hamer, M., & Chida, Y. (2007). The effects of acute psychological stress on circulating inflammatory factors in humans: A review and meta-analysis. Brain, Behavior, and Immunity, 21(7), 901–912.
9. Sjogren, E., Leanderson, P., Kristenson, M., & Ernerudh, J. (2006). Interleukin-6 levels in relation to psychosocial factors: Studies on serum, saliva, and in vitro production by blood mononuclear cells. Brain, Behavior, and Immunity, 20(3), 270–278.
10. Dantzer, R., & Kelley, K. W. (2007). Twenty years of research on cytokine-induced sickness behavior. Brain, Behavior, and Immunity,21(2), 153–160.
11. Rabin, B. S. (1999). Stress, immune function, and health: The connection. New York, NY: Wiley-Liss.
12. Christian, L. M., Glaser, R., Porter, K., Malarkey, W. B., Beversdorf, D., & Kiecolt-Glaser, J. K. (2011). Poorer self-rated health is associated with elevated inflammatory markers among older adults. Psychoneuroendocrinology,36(10), 1495–1504.
13. Cohen, H. J., Pieper, C. F., Harris, T., Rao, K. M., & Currie, M. S. (1997). The association of plasma IL-6 levels with functional disability in community-dwelling elderly. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences,52(4), M201–M208.
14. Lekander, M., Elofsson, S., Neve, I. M., Hansson, L. O., & Unden, A. L. (2004). Self-rated health is related to levels of circulating cytokines. Psychosomatic Medicine,66(4), 559–563.
15. Janszky, I., Lekander, M., Blom, M., Georgiades, A., & Ahnve, S. (2005). Self-rated health and vital exhaustion, but not depression, is related to inflammation in women with coronary heart disease. Brain, Behavior, and Immunity,19(6), 555–563.
16. Baturone, R., Soto, M. J., Marquez, M., Macias, I., de Oca, M. M., Medina, F., et al. (2009). Health-related quality of life in patients with primary Sjogren’s syndrome: Relationship with serum levels of proinflammatory cytokines. Scandinavian Journal of Rheumatology,38(5), 386–389.
17. Costanzo, E. S., Lutgendorf, S. K., Sood, A. K., Anderson, B., Sorosky, J., & Lubaroff, D. M. (2005). Psychosocial factors and interleukin-6 among women with advanced ovarian cancer. Cancer,104(2), 305–313.
18. Falasca, K., Mancino, P., Ucciferri, C., Dalessandro, M., Manzoli, L., Pizzigallo, E., et al. (2009). Quality of life, depression, and cytokine patterns in patients with chronic hepatitis C treated with antiviral therapy. Clinical and Investigative Medicine,32(3), E212–E218.
19. Knobel, H., Loge, J. H., Nordoy, T., Kolstad, A. L., Espevik, T., Kvaloy, S., & Kaasa, S. (2000). High level of fatigue in lymphoma patients treated with high dose therapy. Journal of Pain and Symptom Management,19(6), 446–456.
20. Matsunaga, M., Isowa, T., Murakami, H., Kasugai, K., Yoneda, M., Kaneko, H., & Ohira, H. (2009). Association of polymorphism in the human µ-opioid receptor OPRM1 gene with proinflammatory cytokine levels and health perception. Brain, Behavior, and Immunity,23(7), 931–935.
21. Miller, L. J., Fischer, K. A., Goralnick, S. J., Litt, M., Burleson, J. A., Albertsen, P., & Kreutzer, D. L. (2002). Nerve growth factor and chronic prostatitis/chronic pelvic pain syndrome. Urology,59(4), 603–608.
22. Miller, L. J., Fischer, K. A., Goralnick, S. J., Litt, M., Burleson, J. A., Albertsen, P., & Kreutzer, D. L. (2002). Interleukin-10 levels in seminal plasma: Implications for chronic prostatitis–chronic pelvic pain syndrome. Journal of Urology,167(2 Pt 1), 753–756.
23. Mommersteeg, P. M., Kupper, N., Schoormans, D., Emons, W., & Pedersen, S. S. (2010). Health-related quality of life is related to cytokine levels at 12 months in patients with chronic heart failure. Brain, Behavior, and Immunity,24(4), 615–622.
24. Rich, T., Innominato, P. F., Boerner, J., Mormont, M. C., Iacobelli, S., Baron, B., et al. (2005). Elevated serum cytokines correlated with altered behavior, serum cortisol rhythm, and dampened 24-hour rest-activity patterns in patients with metastatic colorectal cancer. Clinical Cancer Research,11(5), 1757–1764.
25. Shyong, E. Q., Lucchinetti, E., Tagliente, T. M., Hossain, S., Silverstein, J. H., & Zaugg, M. (2003). Interleukin balance and early recovery from anesthesia in elderly surgical patients exposed to beta-adrenergic antagonism. Journal of Clinical Anesthesia,15(3), 170–178.
26. Spruit, M. A., Gosselink, R., Troosters, T., Kasran, A., Van Vliet, M., & Decramer, M. (2005). Low-grade systemic inflammation and the response to exercise training in patients with advanced COPD. Chest,128(5), 3183–3190.
27. Cummings, D. M., King, D. E., & Mainous, A. G, 3rd. (2003). C-reactive protein, antiinflammatory drugs, and quality of life in diabetes. Annals of Pharmacotherapy,37(11), 1593–1597.
28. Dagfinrud, H., Vollestad, N. K., Loge, J. H., Kvien, T. K., & Mengshoel, A. M. (2005). Fatigue in patients with ankylosing spondylitis: A comparison with the general population and associations with clinical and self-reported measures. Arthritis and Rheumatism,53(1), 5–11.
29. Kalender, B., Ozdemir, A. C., Dervisoglu, E., & Ozdemir, O. (2007). Quality of life in chronic kidney disease: Effects of treatment modality, depression, malnutrition and inflammation. International Journal of Clinical Practice,61(4), 569–576.
30. Ribu, L., Hanestad, B. R., Moum, T., Birkeland, K., & Rustoen, T. (2007). Health-related quality of life among patients with diabetes and foot ulcers: Association with demographic and clinical characteristics. Journal of Diabetes and Its Complications,21(4), 227–236.
31. Cho, H. J., Kivimaki, M., Bower, J. E., & Irwin, M. R. (2013). Association of C-reactive protein and interleukin-6 with new-onset fatigue in the Whitehall II prospective cohort study. Psychological Medicine, 43(8), 1773–1783.
32. Wikby, A., Nilsson, B. O., Forsey, R., Thompson, J., Strindhall, J., Lofgren, S., et al. (2006). The immune risk phenotype is associated with IL-6 in the terminal decline stage: Findings from the Swedish NONA immune longitudinal study of very late life functioning. Mechanisms of Ageing and Development,127(8), 695–704.
33. Harris, T. B., Ferrucci, L., Tracy, R. P., Corti, M. C., Wacholder, S., Ettinger, W. H, Jr, et al. (1999). Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. The American Journal of Medicine,106(5), 506–512.
34. Hollman, G., & Kristenson, M. (2008). The prevalence of the metabolic syndrome and its risk factors in a middle-aged Swedish population—Mainly a function of overweight? European Journal of Cardiovascular Nursing, 7(1), 21–26.
35. Sullivan, M., Karlsson, J., & Ware, J. E, Jr. (1995). The Swedish SF-36 Health Survey—I. Evaluation of data quality, scaling assumptions, reliability and construct validity across general populations in Sweden. Social Science and Medicine,41(10), 1349–1358.
36. Khani, B. R., Ye, W., Terry, P., & Wolk, A. (2004). Reproducibility and validity of major dietary patterns among Swedish women assessed with a food-frequency questionnaire. Journal of Nutrition,134(6), 1541–1545.
37. Kallings, L. V., Leijon, M., Hellenius, M. L., & Stahle, A. (2008). Physical activity on prescription in primary health care: A follow-up of physical activity level and quality of life. Scandinavian Journal of Medicine and Science in Sports, 18(2), 154–161.
38. Radloff, L. (1977). The CES-D scale. A self-report depression scale for research in the general population. Applied Psychological Measures,1(3), 385–401.
39. Antonovsky, A. (1987). Unraveling the mystery of health: How people manage stress and stay well (1st ed.). San Francisco: Jossey-Bass.
40. Walters, S. J., & Campbell, M. J. (2004). The use of bootstrap methods for analysing health-related quality of life outcomes (particularly the SF-36). Health and Quality of Life Outcomes,2, 70.
41. Pearson, T. A., Mensah, G. A., Alexander, R. W., Anderson, J. L., Cannon, R. O, 3rd, Criqui, M., et al. (2003). Markers of inflammation and cardiovascular disease: Application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation,107(3), 499–511.