Kinetics of tris (1-chloro-2-propyl) phosphate (TCIPP) metabolism in human liver microsomes and serum

Chemosphere

Volumn 144, Issue , 2016, Pages 1299-1305

  Van den Eede, Nele ^a   Tomy, Gregg ^b   Tao, Fang ^c   Halldorson, Thor ^b   Harrad, Stuart ^c   Neels, Hugo ^a   Covaci, Adrian ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b UNIVERSITY OF MANITOBA   (Canada)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Biotransformation; Clearance; Liver; Organophosphate flame retardant; Serum

Indexed keywords

BIOCONVERSION; BODY FLUIDS; LIVER;

BIOTRANSFORMATION; BIOTRANSFORMATION REACTIONS; CLEARANCE; HUMAN LIVER MICROSOMES; MICHAELIS-MENTEN MODEL; ORGANOPHOSPHATE FLAME RETARDANTS; QUANTITATIVE ASSESSMENTS; SERUM;

METABOLITES;

BIS (1 CHLORO 2 PROPYL) 1 HYDROXY 2 PROPYLPHOSPHATE; BIS (2 CHLOROISOPROPYL)PHOSPHATE; FLAME RETARDANT; TRIS (1 CHLORO 2 PROPYL)PHOSPHATE; UNCLASSIFIED DRUG; ORGANOPHOSPHORUS COMPOUND; POLLUTANT; TRIS(1-CHLORO-2-PROPYL)PHOSPHATE;

BIOTRANSFORMATION; KINETICS; METABOLISM; ORGANOPHOSPHORUS PESTICIDE; PHOSPHATE; SERUM;

ARTICLE; BIOTRANSFORMATION; COMPARATIVE STUDY; CONTROLLED STUDY; HEPATIC CLEARANCE; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; IN VIVO STUDY; INTRINSIC CLEARANCE; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MAXIMUM REACTION VELOCITY; METABOLISM; MICHAELIS MENTEN KINETICS; QUADRUPOLE MASS SPECTROMETRY; SERUM; STEADY STATE; SUBSTRATE CONCENTRATION; BLOOD; CHEMICAL STRUCTURE; CHEMISTRY; ENVIRONMENTAL MONITORING; ENZYMOLOGY; ISOMERISM; KINETICS; MASS SPECTROMETRY; POLLUTANT; PROCEDURES;

BIOTRANSFORMATION; CHROMATOGRAPHY, LIQUID; ENVIRONMENTAL MONITORING; ENVIRONMENTAL POLLUTANTS; FLAME RETARDANTS; HUMANS; IN VITRO TECHNIQUES; ISOMERISM; KINETICS; MASS SPECTROMETRY; MICROSOMES, LIVER; MOLECULAR STRUCTURE; ORGANOPHOSPHORUS COMPOUNDS;

EID: 84953791615     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2015.09.049     Document Type: Article

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