Challenges in the characterization of neutrophil extracellular traps: The truth is in the details

European Journal of Immunology

Volumn 46, Issue 1, 2016, Pages 52-55

  Naccache, Paul H ^a   Fernandes, Maria J G ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Necrosis; NET formation; Neutrophil; RIPK

Indexed keywords

CYTOPLASM PROTEIN; MIXED LINEAGE KINASE DOMAIN LIKE PROTEIN; PROTEIN SERINE THREONINE KINASE; RECEPTOR INTERACTING PROTEIN KINASE 1; RECEPTOR INTERACTING PROTEIN KINASE 3; UNCLASSIFIED DRUG; PROTEIN KINASE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE;

ARTICLE; CELL DEATH; CHROMATIN; CHROMATIN STRUCTURE; EXTRACELLULAR TRAP; FLOW CYTOMETRY; HUMAN; IMMUNE RESPONSE; NETOSIS; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; ANIMAL; FEMALE; IMMUNOLOGY; METABOLISM;

ANIMALS; EXTRACELLULAR TRAPS; FEMALE; HUMANS; PROTEIN KINASES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 84953776243     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201546022     Document Type: Article

References (16)

1. Cascao, R., Rosario, H. S. and Fonseca, J. E., Neutrophils: warriors and commanders in immune mediated inflammatory diseases. Acta Reumatol. Port. 2009. 34: 313-326
2. Kumar, V. and Sharma, A., Neutrophils, Cinderella of innate immune system. Int. Immunopharmacol. 2010. 10: 1325-1334
3. Edwards, S. W., Wright, H. L., Moots, R. J. and Bucknall, R. C., Neutrophil function in inflammation and inflammatory diseases. Rheumatology 2010. 49: 1618-1631
4. Brinkmann, V., Reichard, U., Goosmann, C., Fauler, B., Uhlemann, Y., Weiss, D. S., Weinrauch, Y. et al., Neutrophil extracellular traps kill bacteria. Science (New York) 2004. 303: 1532-1535
5. Grayson, P. C. and Kaplan, M. J., At the bench: neutrophil extracellular traps (NETs) highlight novel aspects of innate immune system involvement in autoimmune diseases. J. Leukocyte Biol. 2015. doi: 10.1189/jlb.5BT0615-247R
6. Galluzzi, L., Vitale, I., Abrams, J. M., Alnemri, E. S., Baehrecke, E. H., Blagosklonny, M. V., Dawson, T. M. et al., Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ. 2012. 19: 107-120
7. Galluzzi, L., Bravo-San Pedro, J. M., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Alnemri, E. S. et al., Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death Differ. 2015. 22: 58-73
8. Pasparakis, M. and Vandenabeele, P., Necroptosis and its role in inflammation. Nature 2015. 517: 311-320
9. Zhou, W. and Yuan, J., Necroptosis in health and diseases. Semin. Cell Dev. Biol. 2014. 35: 14-23
10. Remijsen, Q., Vanden Berghe, T., Wirawan, E., Asselbergh, B., Parthoens, E., De Rycke, R., Noppen, S. et al., Neutrophil extracellular trap cell death requires both autophagy and superoxide generation. Cell Res. 2011. 21: 290-304
11. Desai, J., Kumar, S. V, Mulay, S. R., Konrad, L., Romoli, S., Schauer, C., Herrmann, M. et al., PMA and crystal-induced neutrophil extracellular trap formation involves RIPK1-RIPK3-MLKL signaling. Eur. J. Immunol. 2016. 46: 223-229.
12. Yipp, B. G. and Kubes, P., NETosis: how vital is it? Blood 2013. 122, 2784-2794
13. Zhao, W., Fogg, D. K. and Kaplan, M. J., A novel image-based quantitative method for the characterization of NETosis. J. Immunol. Methods 2015. 423: 104-110
14. Stoiber, W., Obermayer, A., Steinbacher, P. and Krautgartner, W. D., The role of reactive oxygen species (ROS) in the formation of extracellular traps (ETs) in Humans. Biomolecules 2015. 5: 702-723.
15. Amini, P., Stojkov, D., Wang, X., Wicki, S., Kaufmann, T., Wong, W.W., Simon, H.-U. et al., NET formation can occur independently of RIPK3 and MLKL signaling. Eur. J. Immunol. 2016. 46: 178-184.
16. Gavillet, M., Martinod, K., Renella, R., Harris, C., Shapiro, N. I., Wagner, D. D. and Williams, D. A., Flow cytometric assay for direct quantification of neutrophil extracellular traps in blood samples. Am. J. Hematol. 2015. 90: 1155-1158.