PrimPol Is Required for Replicative Tolerance of G Quadruplexes in Vertebrate Cells

Molecular Cell

Volumn 61, Issue 1, 2016, Pages 161-169

  Schiavone, Davide ^a   Jozwiakowski, Stanislaw K ^b   Romanello, Marina ^a   Guilbaud, Guillaume ^a   Guilliam, Thomas A ^b   Bailey, Laura J ^b   Sale, Julian E ^a   Doherty, Aidan J ^b  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

Epigenetic instability; G quadruplexes; Polymerase; Primase; PrimPol; Replication stalling; Repriming; TLS

Indexed keywords

DNA; DNA POLYMERASE; DNA PRIMASE; GUANINE QUADRUPLEX; HELICASE; HISTONE; PRIMPOL; PROTEIN; UNCLASSIFIED DRUG; AVIAN PROTEIN; DNA DIRECTED DNA POLYMERASE; MULTIFUNCTIONAL ENZYME; PRIMPOL PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CATALYSIS; CELLS; CONTROLLED STUDY; DNA REPLICATION; DNA SEQUENCE; DNA STRAND; DNA SYNTHESIS; EPIGENETICS; GENE LOCUS; GENETIC STABILITY; NONHUMAN; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; ZINC FINGER MOTIF; ANIMAL; BIOSYNTHESIS; CELL LINE; CHEMISTRY; CHICKEN; CHROMATIN ASSEMBLY AND DISASSEMBLY; GENETIC EPIGENESIS; GENETIC TRANSFECTION; GENETICS; GENOMIC INSTABILITY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE;

ANIMALS; AVIAN PROTEINS; BASE SEQUENCE; CELL LINE; CHICKENS; CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA; DNA PRIMASE; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; EPIGENESIS, GENETIC; G-QUADRUPLEXES; GENOMIC INSTABILITY; HISTONES; MOLECULAR SEQUENCE DATA; MULTIFUNCTIONAL ENZYMES; TRANSFECTION;

EID: 84953637846     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.10.038     Document Type: Article

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