Association of serum Nε-Carboxy methyl lysine with severity of diabetic retinopathy

Journal of Diabetes and its Complications

Volumn 30, Issue 3, 2016, Pages 511-517

  Mishra, Nibha ^a   Saxena, Sandeep ^a   Shukla, Rajendra K ^b   Singh, Vinita ^a   Meyer, Carsten H ^c   Kruzliak, Peter ^d,e   Khanna, Vinay K ^b  

^a KING GEORGE'S MEDICAL UNIVERSITY   (India)

^b CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^c Klinik Pallas   (Switzerland)

^d Physics and Informatics   (Slovakia)

^e ST ANNE S UNIVERSITY HOSPITAL   (Czech Republic)

Author keywords

Advanced glycation end products; Diabetic macular edema; Diabetic retinopathy; External limiting membrane; N epsilon carboxy methyl lysine; Photoreceptor ellipsoid zone

Indexed keywords

6 N CARBOXYMETHYLLYSINE; ADVANCED GLYCATION END PRODUCT; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C; BIOLOGICAL MARKER; LYSINE; N(6)-CARBOXYMETHYLLYSINE;

ADULT; AMINO ACID BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; DIABETIC MACULAR EDEMA; DIABETIC RETINOPATHY; DISEASE SEVERITY; FEMALE; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HUMAN; MACULAR THICKNESS; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROLIFERATIVE DIABETIC RETINOPATHY; SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY; AGED; ANALOGS AND DERIVATIVES; BLOOD; CASE CONTROL STUDY; COMPLICATION; MIDDLE AGED; PATHOLOGY; SEVERITY OF ILLNESS INDEX;

ADULT; AGED; BIOMARKERS; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; FEMALE; HUMANS; LYSINE; MALE; MIDDLE AGED; SEVERITY OF ILLNESS INDEX;

EID: 84953439131     PISSN: 10568727     EISSN: 1873460X     Source Type: Journal    
DOI: 10.1016/j.jdiacomp.2015.12.009     Document Type: Article

References (43)

1. Y. Akagi-Kurashige, A. Tsujikawa, A. Oishi, S. Ooto, K. Yamashiro, and H. Tamura N. Yoshimura Relationship between retinal morphological findings and visual function in age-related macular degeneration Graefe's Archive for Clinical and Experimental Ophthalmology 250 2012 1129 1136
2. B.O. Boehm, S. Schilling, S. Rosinger, G.E. Lang, G.K. Lang, R. Kientsch-Engel, and P. Stahl Elevated serum levels of N ε-carboxymethyl-lysine, an advanced glycation end product, are associated with proliferative diabetic retinopathy and macular oedema Diabetologia 47 2004 1376 1379
3. M. Brownlee, A. Cerami, and H. Vlassara Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications The New England Journal of Medicine 318 1988 1315 1321
4. A.H. Bunt-Milam, J.C. Saari, I.B. Klock, and G.G. Garwin Zonulae adherentes pore size in the external limiting membrane of the rabbit retina Investigative Ophthalmology & Visual Science 26 1985 1377 1380
5. N.C. Chilelli, S. Burlina, and A. Lapolla AGEs, rather than hyperglycemia, are responsible for microvascular complications in diabetes: A »glycoxidation-centric» point of view Nutrition, Metabolism, and Cardiovascular Diseases 23 2013 913 919
6. S. Choudhuri, D. Dutta, A. Sen, I.H. Chowdhury, B. Mitra, and L.K. Mondal B. Bhattacharya Role of N-epsilon-carboxy methyl lysine, advanced glycation end products and reactive oxygen species for the development of nonproliferative and proliferative retinopathy in type 2 diabetes mellitus Molecular Vision 19 2013 100 113
7. Early treatment diabetic retinopathy study research group. Grading diabetic retinopathy from stereoscopic color fundus photographs. ETDRS report number 10 Ophthalmology 98 1991 786 806
8. P. Frederick, F. Yuxi, H. Franziska, H. Sigrid, M. Grietje, and J. Hillebrands H. Hammes Pericyte migration. A novel mechanism of pericyte loss in experimental diabetic retinopathy Diabetes 57 2008 2495 2502
9. W.S. Foulds, C. Kaur, C.D. Luu, and W.K. Kek A role for photoreceptors in retinal oedema and angiogenesis: An additional explanation for laser treatment? Eye (London, England) 24 2010 918 926
10. R.E. Gangnon, M.D. Davis, L.D. Hubbard, L.M. Aiello, E.Y. Chew, F.L.I.I.I. Ferris, M.R. Fisher Early Treatment Diabetic Retinopathy Study Research Group A severity scale for diabetic macular edema developed from ETDRS data Investigative Ophthalmology & Visual Science 49 2008 5041 5047
11. K.F. Hanssen Blood glucose control and microvascular and macrovascular complications Diabetes 46 1997 101 103
12. K. Hirata, and K. Kubo Relationship between blood levels of N-carboxymethyl-lysine and pentosidine and the severity of microangiopathy in type 2 diabetes Endocrine Journal 51 2004 537 544
13. D. Huang, E.A. Swanson, C.P. Lin, J.S. Schuman, W.G. Stinson, W. Chang, J.G. Fujimoto, and et al. Optical coherence tomography Science 254 1991 1178 1181
14. A. Jain, S. Saxena, V.K. Khanna, R.K. Shukla, and C.H. Meyer Status of serum VEGF and ICAM-1 and its association with external limiting membrane and inner segment-outer segment junction disruption in type 2 diabetes mellitus Molecular Vision 19 2013 1760 1768
15. P. Kang, C. Tian, and C. Jia Association of RAGE gene polymorphisms with type 2 diabetes mellitus, diabetic retinopathy and diabetic nephropathy Gene 500 2012 1 9
16. H. Kawashima, K. Mizukawa, I. Watanabe, H. Kamao, and J. Kiryu Evaluation of recovery process of photoreceptor outer segment after retinal detachment repair Nippon Ganka Gakkai Zasshi 115 2011 374 381
17. A.S. Maheshwary, S.F. Oster, R.M. Yuson, L. Cheng, F. Mojana, and W.R. Freeman The association between percent disruption of the photoreceptor inner segment-outer segment junction and visual acuity in diabetic macular edema American Journal of Ophthalmology 150 2010 63 67
18. A.K. Mehalow, S. Kameya, R.S. Smith, N.L. Hawes, J.M. Denegre, and J.A. Young P.M. Nishina CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina Human Molecular Genetics 12 2003 2179 2189
19. Y. Mitamura, K. Hirano, T. Baba, and S. Yamamoto Correlation of visual recovery with presence of photoreceptor inner/outer segment junction in optical coherence images after epiretinal membrane surgery The British Journal of Ophthalmology 93 2009 171 175
20. T. Murakami, K. Nishijima, T. Akagi, A. Uji, T. Horii, and N.U. Arakawa N. Yoshimura Optical coherence tomographic reflectivity of photoreceptors beneath cystoid spaces in diabetic macular edema Investigative Ophthalmology & Visual Science 53 2012 1506 1511
21. T. Murakami, K. Nishijima, A. Sakamoto, M. Ota, T. Horii, and N. Yoshimura Association of pathomorphology, photoreceptor status, and retinal thickness with visual acuity in diabetic retinopathy American Journal of Ophthalmology 151 2011 310 317
22. T. Murakami, and N. Yoshimura Structural changes in individual retinal layers in diabetic macular edema Journal of Diabetes Research 2013 2013 920713
23. R.R. Pappuru, Y. Ouyang, M.G. Nittala, H.D. Hemmati, P.A. Keane, A.C. Walsh, and S.R. Sadda Relationship between outer retinal thickness substructures and visual acuity in eyes with dry age-related macular degeneration Investigative Ophthalmology & Visual Science 52 2011 6743 6748
24. W.M. Peterson, Q. Wang, R. Tzekova, and S.J. Wiegand Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia The Journal of Neuroscience 20 2000 4081 4090
25. A. Puddu, R. Sanguineti, A. Durante, M. Nicolò, and G.L. Viviani Vascular endothelial growth factor-C secretion is increased by advanced glycation end-products: Possible implication in ocular neovascularization Molecular Vision 18 2012 2509 2517
26. S. Raposeiras-Roubín, B.K. Rodiño-Janeiro, B. Paradela-Dobarro, L. Grigorian-Shamagian, J.M. García-Acuña, and P. Aguiar-Souto E. Álvarez Fluorescent advanced glycation end products and their soluble receptor: The birth of new plasmatic biomarkers for risk stratification of acute coronary syndrome PloS One 8 2013 e74302
27. C.G. Schalkwijk, N. Ligtvoet, H. Twaalfhoven, A. Jager, H.G. Blaauwgeers, and R.O. Schlingemann V.W. van Hinsbergh Amadori albumin in type 1 diabetic patients: Correlation with markers of endothelial function, association with diabetic nephropathy, and localization in retinal capillaries Diabetes 48 1999 2446 2453
28. A.K. Sharma, D.J. Lapar, M.L. Stone, Y. Zhao, I.L. Kron, and V.E. Laubach Receptor for advanced glycation end products (RAGE) on iNKT cells mediates lung ischemia-reperfusion injury American Journal of Transplantation 9 2013 2255 2267
29. Y. Sharma, S. Saxena, A. Mishra, A. Saxena, and S.M. Natu Advanced glycation end products and diabetic retinopathy Journal of Ocular Biology, Diseases, and Informatics 5 2013 63 69
30. S. Sharma, S. Saxena, K. Srivastav, R.K. Shukla, N. Mishra, and C.H. Meyer V.K. Khanna Nitric oxide and oxidative stress is associated with severity of diabetic retinopathy and retinal structural alterations Clinical & Experimental Ophthalmology 43 2015 429 436
31. H.J. Shin, H. Chung, and H.C. Kim Association between integrity of foveal photoreceptor layer and visual outcome in retinal vein occlusion Acta Ophthalmologica 89 2011 35 40
32. A.W. Stitt, C.J. He, and H. Vlassara Characterization of the advanced glycation endproduct receptor complex in human vascular endothelial cells Biochemical and Biophysical Research Communications 256 1999 549 556
33. A.W. Stitt, Y.M. Li, T.A. Gardiner, R. Bucala, D.B. Archer, and H. Vlassara Advanced glycated end- products (AGE) co-localise with AGE receptors in the retinal vasculature of diabetic and AGE infused rats The American Journal of Pathology 150 1997 523 539
34. P. Strozecki, R. Kurowski, M. Flisinski, A. Stefanska, G. Odrowaz-Sypniewska, and J. Manitius Advanced glycation end products and arterial stiffness in diabetic and non-diabetic patients with chronic kidney disease Polskie Archiwum Medycyny Wewnętrznej 123 2013 609 616
35. P.G. Theodossiadis, V.G. Grigoropoulos, and G.P. Theodossiadis The significance of the external limiting membrane in the recovery of photoreceptor layer after successful macular hole closure: A study by spectral domain optical coherence tomography Ophthalmologica 225 2011 176 184
36. P. Ulrich, and A. Cerami Protein glycation, diabetes, and aging Recent Progress in Hormone Research 56 2001 1 21
37. G. Virgili, F. Menchini, V. Murro, E. Peluso, F. Rosa, and G. Casazza Optical coherence tomography (OCT) for detection of macular oedema in patients with diabetic retinopathy Cochrane Database of Systematic Reviews 7 2011 CD008081
38. H. Vlassara, W. Cai, J. Crandall, T. Goldberg, R. Oberstein, and V. Dardaine E.J. Rayfield Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy Proceedings of the National Academy of Sciences of the United States of America 99 2002 15596 15601
39. K. Wahlin, P. Campochiaro, D. Zack, and R. Adler Neurotrophic factors cause activation of intracellular signaling pathways in Müller cells and other cells of the inner retina, but not photoreceptors Investigative Ophthalmology & Visual Science 41 2000 927 936
40. S. Yamagishi, S. Amano, and Y. Inagaki Advanced glycation end productsinduced apoptosis and overexpression of vascular endo thelial growth factor in bovine retinal pericytes Biochemical and Biophysical Research Communications 290 2002 973 978
41. S. Yamagishi, Y. Inagaki, S. Amano, T. Okamoto, M. Takeuchi, and Z. Makita Pigment epithelium-derived factor protects cultured retinal pericytes from advanced glycation end product induced injury through its antioxidative properties Biochemical and Biophysical Research Communications 296 2002 877 882
42. S. Yamagishi, S. Ueda, T. Matsui, K. Nakamura, T. Imaizumi, M. Takeuchi, and S. Okuda Pigment epithelium-derived factor (PEDF) prevents advanced glycation end products (AGEs)-elicited endothelial nitric oxide synthase (eNOS) reduction through its anti-oxidative properties Protein and Peptide Letters 14 2007 832 835
43. H. Zong, M. Ward, and A.W. Stitt AGEs, RAGE, and diabetic retinopathy Current Diabetes Reports 11 2011 244 252