Role of N-epsilon- carboxy methyl lysine, advanced glycation end products and reactive oxygen species for the development of nonproliferative and proliferative retinopathy in type 2 diabetes mellitus

Molecular Vision

Volumn 19, Issue , 2013, Pages 100-113

  Choudhuri, Subhadip ^a   Dutta, Deep ^a   Sen, Aditi ^a   Chowdhury, Imran Hussain ^a   Mitra, Bhaskar ^c   Mondal, Lakshmi Kanta ^b   Saha, Avijit ^a   Bhadhuri, Gautam ^b   Bhattacharya, Basudev ^a  

^a INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

^b Regional Institute of Ophthalmology   (India)

^c Midnapore Medical College   (India)

Author keywords

[No Author keywords available]

Indexed keywords

6 N CARBOXYMETHYLLYSINE; ADVANCED GLYCATION END PRODUCT; GLUCOSE; REACTIVE OXYGEN METABOLITE; THIOL; DRUG DERIVATIVE; LYSINE; N(6) CARBOXYMETHYLLYSINE; N(6)-CARBOXYMETHYLLYSINE; THIOL DERIVATIVE;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DIABETIC RETINOPATHY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONPROLIFERATIVE DIABETIC RETINOPATHY; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RETINOPATHY; SPECTROPHOTOMETRY; UPREGULATION; AGED; BLOOD; CASE CONTROL STUDY; CROSS-SECTIONAL STUDY; METABOLISM; MIDDLE AGED; MONONUCLEAR CELL; PATHOLOGY; VITREOUS BODY;

ADULT; AGED; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; FEMALE; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; LEUKOCYTES, MONONUCLEAR; LYSINE; MALE; MIDDLE AGED; REACTIVE OXYGEN SPECIES; SULFHYDRYL COMPOUNDS; VITREOUS BODY;

EID: 84873140767     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Fong DS, Aiello LP, Ferris FL, Klein R. Diabetic retinopathy Diabetes Care 2004; 27:2540-53. [PMID: 15451934.
2. Kern TS, Tang J, Mizutani M, Kowluru RA, Nagaraj RH, Romeo G, Podesta F, Lorenzi M. Response of capillary cell death to aminoguanidine predicts the development of retinopathy: comparison of diabetes and galactosemia. Invest Ophthalmol Vis Sci 2000; 41:3972-8. [PMID: 11053301.
3. Kowluru RA, Chan PS. Oxidative stress and diabetic retinopathy. Exp Diabetes Res 2007; 2007:43603. [PMID: 17641741].
4. Stitt AW. AGES and diabetic retinopathy. Invest Ophthalmol Vis Sci 2010; 51:4867-74. [PMID: 20876889.
5. Monnier VM, Sell DR, Genuth S. Glycation products as markers and predictors of the progression of diabetic complications Ann N Y Acad Sci 2005; 1043:567-81. [PMID: 16037280].
6. Yamagishi S, Nakamura K, Imaizumi T. Advanced glycation end products (AGEs) and diabetic vascular complications Curr Diabetes Rev 2005; 1:93-106. [PMID: 18220586.
7. Hammes HP, Brownlee M, Lin J, Schleicher E, Bretzel RG. Diabetic retinopathy risk correlates with intracellular concentrations of the glycoxidation product N - (carboxymethyl) lysine independently of glycohaemoglobin concentrations Diabetologia 1999; 42:603-7. [PMID: 10333054.
8. Schleicher ED, Wagner E, Nerlich AG. Increased accumulation of the glycoxidation product N (epsilon) - (carboxy methyl) lysine in human tissues in diabetes and aging. J Clin Invest 1997; 99:457-68. [PMID: 9022079.
9. εcarboxy methyl lysine, an advanced glycation end product, are associated with proliferative diabetic retinopathy and macular oedema Diabetologia 2004; 47:1376-9. [PMID: 15258735.
10. Goldin A, Beckman JA, Schmidt AM, Creager MA. Advanced glycation end products sparking the development of diabetic vascular injury Circulation 2006; 114:597-605. [PMID: 16894049].
11. Basta G, Lazzerini G, Massaro M, Simoncini T, Tanganelli P, Fu C, Kislinger T, Stern DM, Schmidt AM, De Caterina R. Advanced glycation end products activate endothelium through signal transduction receptor RAGE; a mechanism for amplification of inflammatory responses Circulation 2002; 105:816-22. [PMID: 11854121.
12. Wautier MP, Chappey O, Corda S, Stern DM, Schmidt AM, Wautier JL. Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE. Am J Physiol Endocrinol Metab 2001; 280:E685-94. [PMID: 11287350].
13. Warboys CM, Toh HB, Fraser PA. Role of NADPH oxidase in retinal microvascular permeability increase by RAGE activation Invest Ophthalmol Vis Sci 2009; 50:1319-28. [PMID: 18997095.
14. Guzik TJ, Mussa S, Gastaldi D, Sadowski J, Ranatunga C, Pillai R. Mechanism of increased vascular superoxide production in human diabetes mellitus: Role of NADPH oxidase and endothelial nitric oxide synthase. Circulation 2002; 105:1656-62. [PMID: 11940543.
15. Izuta H, Matsunaga N, Shimazawa M, Sugiyama T, Ikeda T. Proliferative diabetic retinopathy and relations among antioxidant activity, oxidative stress and VEGF in the vitreous body Mol Vis 2010; 16:130-6. [PMID: 20142849.
16. Tain YL, Baylis C. Dissecting the causes of oxidative stress in an in vivo model of hypertension. Hypertension 2006; 48:828-9. [PMID: 17015781.
17. Channon KM, Guzik TJ. Mechanism of superoxide production in human blood vessels J Physiol Pharmacol 2002; 53:515-24. [PMID: 12512689.
18. Landmesser U, Dikalov S, Price SR. Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension J Clin Invest 2003; 111:1201-9. [PMID: 12697739.
19. Rossi R, Giustarini D, Milzani A, Dalledonne I. Cysteinylation and homocysteinylation of plasma protein thiols during ageing of healthy humans J Cell Mol Med 2009; 13:9b3131-40. [PMID: 18624771].
20. Baskol G, Gumus K, Oner A, Arda H, Karakucuk S. The role of advanced oxidation of protein products and total thiols in diabetic retinopathy Eur J Ophthalmol 2008; 18:792-8. [PMID: 18850560.
21. World Health Organization. Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia: Report of a WHO/IDF Consultation: Diagnosis and Classification of Diabetes Mellitus. Geneva, World Health Organization 2006.
22. Eligini S, Stella BS, Cavalca V, Camera M, Brambilla M, De Franceschi M, Tremoli E, Colli S. Diversity and similarity in signalling events leading to rapid Cox 2 induction by tumor necrosis factor alpha and phorbol ester in human endothelial cells Cardiovasc Res 2005; 65:683-93. [PMID: 15664395.
23. Gu Y, Xu YC, Wu RF, Souza RF, Nwariaku FE, Terada LS. TNF alpha activates c - Jun N-terminal kinase through p47(phox) Exp Cell Res 2002; 272:62-4. [PMID: 11740866.
24. Stachowska E, Masiuk MB, Machalinski B, Rybicka M, Gutowska I, Bober J, Grymula K, Dziedziejko V, Chlubek D. Sodium fluoride enhancement of monocyte differentiation via nuclear factor kB mechanism Research Report Fluoride 2005; 38:297-306.
25. Ellman GL. Tissue sulfhydryl groups Arch Biochem Biophys 1959; 82:70-7. [PMID: 13650640.
26. Hu ML. Measurement of protein thiol groups and glutathione in plasma Methods Enzymol 1994; 233:380-5. [PMID: 8015473].
27. Bhavsar AR. Diabetic retinopathy: the latest in current management. Retina 2006; 26:S71-9. [PMID: 16832305.
28. Crawford TN, Alfaro DV, Kerrison JB, Jablon EP. Diabetic retinopathy and angiogenesis Curr Diabetes Rev 2009; 5:8-13. [PMID: 19199892.
29. Mohamed Q, Gillies MC, Wong TY. Management of diabetic retinopathy, a systematic review JAMA 2007; 298:902-916. [PMID: 17712074.
30. Yamagishi S, Ueda S, Matsui T, Nakamura K, Okuda S. Role of advanced glycation end products (AGEs) and oxidative stress in diabetic retinopathy Curr Pharm Des 2008; 14:962-8. [PMID: 18473846.
31. Stitt AW, Bhadhuri T, Mc Mullen CB, Gardiner TA, Archer DB. Advanced glycation end products induce blood retinal barrier dysfunction in normoglycemic rats Mol Cell Biol Res Commun 2000; 3:380-8. [PMID: 11032761.
32. Murata T, Nagai R, Ishibashi T, Inomuta H, Ikeda K, Horiuchi S. The relationship between accumulation of advanced glycation end products (AGEs) and expression of vascular endothelial growth factor in human diabetic retinas Diabetologia 1997; 40:764-9. [PMID: 9243096.
33. Bierhaus A, Illmer T, Kasper M, Luther T, Quehenberger P, Tritschler H, Wahl P, Ziegler R, Muller M, Nawroth PP. Advanced glycation end product (AGE) mediated induction of tissue factor in cultured endothelial cells is dependent on RAGE Circulation 1997; 96:2262-71. [PMID: 9337199.
34. Yan SD, Schmidt AM, Anderson GM, Zhang J, Brett J, Zou YS, Pinsky D, Stern D. Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins. J Biol Chem 1994; 269:9889-97. [PMID: 8144582.
35. Rojas A, Romay S, Gonjalez D, Herrera B, Delgado R, Otero K. Regulation of endothelial nitric oxide synthase expression by albumin derived advanced glycosylation end products. Circ Res 2000; 86:E50-4. [PMID: 10679490.
36. Hogan M, Cerami A, Bucala R. Advanced glycosylation end products block the anti proliferative effect of nitric oxide: role in the vascular and renal complications of diabetes mellitus J Clin Invest 1992; 90:1110-5. [PMID: 1522220.
37. Yamagishi S, Fujimori H, Yonekura H. Advanced glycation end products inhibits prostacyclin production and induce plasminogen activator inhibitor-1 in human microvascular endothelial cells Diabetologia 1998; 41:1435-41. [PMID: 9867210.
38. Yamagishi S, Yamamoto Y, Harada S. Advanced glycosylation end products stimulate the growth but inhibit the prostacyclinproducing ability of endothelial cells through interactions with their receptors FEBS Lett 1996; 384:103-6. [PMID: 8797813.
39. Grossin N, Wautier MP, Meas T, Guillausseau PJ, Massin P, Wautier JL. Severity of diabetic microvascular complications is associated with a low soluble RAGE level Diabetes Metab 2008; 34:392-5. [PMID: 18701333.
40. Wautier MP, Massin P, Guillausseau PJ, Huijberts M, Levy B, Boulanger EN. (carboxymethyl) lysine as a biomarker for microvascular complications in type 2 diabetic patients Diabetes Metab 2003; 29:44-52. [PMID: 12629447.
41. Scott JE. The chemical morphology of the vitreous Eye (Lond) 1992; 6:553-5. [PMID: 1289129.
42. Stitt AW, Moore JE, Sharkey JA, Murphy G, Simpson DA, Bucala R, Vlassara H, Archer DB. Advanced glycation end products in vitreous: structural and functional implications for diabetic vitreopathy Invest Ophthalmol Vis Sci 1998; 39:2517-23. [PMID: 9856760.
43. Kaneto H, Katakami N, Matsuhisa M, Matsuoka TA. Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis. Mediators Inflamm 2010; 2010:453-892. [PMID: 20182627.
44. Robertson RP, Harmon J, Tran PO, Tanaka Y, Takahashi H. Glucose toxicity in β cells: type 2 diabetes good radicals gone bad and the glutathione connection Diabetes 2003; 52:581-7. [PMID: 12606496.
45. Harrison D, Griendling KK, Landmesser U, Hornig B, Drexler H. Role of oxidative stress in atherosclerosis Am J Cardiol 2003; 91:7A-11A. [PMID: 12645638.
46. Esposito K, Nappo F, Marfella R. Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress Circulation 2002; 106:2067-72. [PMID: 12379575.
47. Ozturk BT, Bozkurt B, Kerimoglu H, Okka M, Kamis U, Gunduz K. Effect of serum cytokinesand VEGF levels on diabetic retinopathy and macular thickness Mol Vis 2009; 15:1906-14. [PMID: 19784389.
48. Nam JS, Cho MH, Lee GT, Park JS, Ahn CW, Cha BS, Lim SK, Kim KR, Ha HJ, Lee HC. The activation of NF- Kappa B and AP 1 in peripheral blood mononuclear cells isolated from patients with diabetic nephropathy Diabetes Res Clin Pract 2008; 81:25-32. [PMID: 18485515.
49. Isoni CA, Borges EA, Veloso CA, Mattos RT, Chaves MM, Nogueira-Machado JA. cAMP activates the generation of reactive oxygen species and inhibits the secretion of IL-6 in peripheral blood mononuclear cells from type 2 diabetic patients. Oxid Med Cell Longev. 2009; 2:317-21. [PMID: 20716919.
50. Mustapha NM, Tarr JM, Kohner EM, Chibber R. NADPH Oxidase versus Mitochondria-Derived ROS in Glucose-Induced Apoptosis of Pericytes in Early Diabetic Retinopathy. J Ophthalmol 2010; 2010:746978 [PMID: 20652059].
51. Yamagishi S, Inagaki Y, Amano S. Pigment epithelium derived factor protects cultured retinal pericytes from advanced glycation end product - induced injury through its antioxidative properties Biochem Biophys Res Commun 2002; 296:877-82. [PMID: 12200129.
52. Inagaki Y, Yamagishi S, Okamoto T. Pigment epithelium derived factor prevents advanced glycation end products - induced monocyte chemoattractant protein 1 production in microvascular endothelial cells by suppressing intra cellular reactive oxygen species generation Diabetologia 2003; 46:284-7. [PMID: 12627328.
53. Okamoto T, Yamagishi S, Inagaki Y. Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin FASEB J 2002; 16:1928-30. [PMID: 12368225.
54. Pasaoglu H, Sancak B, Burkan N. Lipid per oxidation and resistance to oxidation in patients with type 2 diabetes mellitus Tohuku J Exp MED 2004; 203:211-8.