-
2
-
-
34548030471
-
National survey of non-small cell lung cancer in the United States: Epidemiology, pathology and patterns of care
-
Little AG, Gay EG, Gaspar LE, Stewart AK. National survey of non-small cell lung cancer in the United States: epidemiology, pathology and patterns of care. Lung Cancer 2007; 57: 253-260.
-
(2007)
Lung Cancer
, vol.57
, pp. 253-260
-
-
Little, A.G.1
Gay, E.G.2
Gaspar, L.E.3
Stewart, A.K.4
-
3
-
-
74949133978
-
American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer
-
Azzoli CG, Baker S Jr, Temin S, Pao W, Aliff T, Brahmer J et al. American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer. J Clin Oncol 2009; 27: 6251-6266.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6251-6266
-
-
Azzoli, C.G.1
Baker, S.2
Temin, S.3
Pao, W.4
Aliff, T.5
Brahmer, J.6
-
5
-
-
0036833980
-
Current status of interleukin-2 therapy for metastatic renal cell carcinoma and metastatic melanoma
-
Dutcher J. Current status of interleukin-2 therapy for metastatic renal cell carcinoma and metastatic melanoma. Oncology (Williston Park) 2002; 16: 4-10.
-
(2002)
Oncology (Williston Park)
, vol.16
, pp. 4-10
-
-
Dutcher, J.1
-
6
-
-
0030030347
-
Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: The Eastern Cooperative Oncology Group trial EST 1684
-
Kirkwood JM, Strawderman MH, Ernstoff MS, Smith TJ, Borden EC, Blum RH. Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: The Eastern Cooperative Oncology Group trial EST 1684. J Clin Oncol 1996; 14: 7-17.
-
(1996)
J Clin Oncol
, vol.14
, pp. 7-17
-
-
Kirkwood, J.M.1
Strawderman, M.H.2
Ernstoff, M.S.3
Smith, T.J.4
Borden, E.C.5
Blum, R.H.6
-
7
-
-
33746547247
-
The biology of interleukin-2 and interleukin-15: Implications for cancer therapy and vaccine design
-
Waldmann TA. The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design. Nat Rev Immunol 2006; 6: 595-601.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 595-601
-
-
Waldmann, T.A.1
-
8
-
-
84855804372
-
Interleukin-15 biology and its therapeutic implications in cancer
-
Steel JC, Waldmann TA, Morris JC. Interleukin-15 biology and its therapeutic implications in cancer. Trends Pharmacol Sci 2012; 33: 35-41.
-
(2012)
Trends Pharmacol Sci
, vol.33
, pp. 35-41
-
-
Steel, J.C.1
Waldmann, T.A.2
Morris, J.C.3
-
9
-
-
0036826914
-
IL-15Ralpha recycles and presents IL-15 in trans to neighboring cells
-
Dubois S, Mariner J, Waldmann TA, Tagaya Y. IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells. Immunity 2002; 17: 537-547.
-
(2002)
Immunity
, vol.17
, pp. 537-547
-
-
Dubois, S.1
Mariner, J.2
Waldmann, T.A.3
Tagaya, Y.4
-
10
-
-
42949147181
-
Intracellular interaction of interleukin-15 with its receptor alpha during production leads to mutual stabilization and increased bioactivity
-
Bergamaschi C, Rosati M, Jalah R, Valentin A, Kulkarni V, Alicea C et al. Intracellular interaction of interleukin-15 with its receptor alpha during production leads to mutual stabilization and increased bioactivity. J Biol Chem 2008; 283: 4189-4199.
-
(2008)
J Biol Chem
, vol.283
, pp. 4189-4199
-
-
Bergamaschi, C.1
Rosati, M.2
Jalah, R.3
Valentin, A.4
Kulkarni, V.5
Alicea, C.6
-
11
-
-
33745135757
-
Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}
-
Rubinstein MP, Kovar M, Purton JF, Cho JH, Boyman O, Surh CD et al. Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}. Proc Natl Acad Sci USA 2006; 103: 9166-9171.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 9166-9171
-
-
Rubinstein, M.P.1
Kovar, M.2
Purton, J.F.3
Cho, J.H.4
Boyman, O.5
Surh, C.D.6
-
12
-
-
42149162887
-
Preassociation of IL-15 with IL-15R alpha-IgG1-Fc enhances its activity on proliferation of NK and CD8 +/CD44high T cells and its antitumor action
-
Dubois S, Patel HJ, Zhang M, Waldmann TA, Muller JR. Preassociation of IL-15 with IL-15R alpha-IgG1-Fc enhances its activity on proliferation of NK and CD8 +/CD44high T cells and its antitumor action. J Immunol 2008; 180: 2099-2106.
-
(2008)
J Immunol
, vol.180
, pp. 2099-2106
-
-
Dubois, S.1
Patel, H.J.2
Zhang, M.3
Waldmann, T.A.4
Muller, J.R.5
-
13
-
-
76249130335
-
Interleukin-15 and its receptor augment dendritic cell vaccination against the neu oncogene through the induction of antibodies partially independent of CD4 help
-
Steel JC, Ramlogan CA, Yu P, Sakai Y, Forni G, Waldmann TA et al. Interleukin-15 and its receptor augment dendritic cell vaccination against the neu oncogene through the induction of antibodies partially independent of CD4 help. Cancer Res 2010; 70: 1072-1081.
-
(2010)
Cancer Res
, vol.70
, pp. 1072-1081
-
-
Steel, J.C.1
Ramlogan, C.A.2
Yu, P.3
Sakai, Y.4
Forni, G.5
Waldmann, T.A.6
-
14
-
-
84922777713
-
Hyper-IL-15 suppresses metastatic and autochthonous liver cancer by promoting tumour-specific CD8+ T cell responses
-
Cheng L, Du X, Wang Z, Ju J, Jia M, Huang Q et al. Hyper-IL-15 suppresses metastatic and autochthonous liver cancer by promoting tumour-specific CD8+ T cell responses. J Hepatol 2014; 61: 1297-1303.
-
(2014)
J Hepatol
, vol.61
, pp. 1297-1303
-
-
Cheng, L.1
Du, X.2
Wang, Z.3
Ju, J.4
Jia, M.5
Huang, Q.6
-
15
-
-
77951945662
-
Treatment of hepatocellular carcinoma with adeno-associated virus encoding interleukin-15 superagonist
-
Chang CM, Lo CH, Shih YM, Chen Y, Wu PY, Tsuneyama K et al. Treatment of hepatocellular carcinoma with adeno-associated virus encoding interleukin-15 superagonist. Hum Gene Ther 2010; 21: 611-621.
-
(2010)
Hum Gene Ther
, vol.21
, pp. 611-621
-
-
Chang, C.M.1
Lo, C.H.2
Shih, Y.M.3
Chen, Y.4
Wu, P.Y.5
Tsuneyama, K.6
-
16
-
-
70349482330
-
High antitumor activity of RLI, an interleukin-15 (IL-15)-IL-15 receptor alpha fusion protein, in metastatic melanoma and colorectal cancer
-
Bessard A, Sole V, Bouchaud G, Quemener A, Jacques Y. High antitumor activity of RLI, an interleukin-15 (IL-15)-IL-15 receptor alpha fusion protein, in metastatic melanoma and colorectal cancer. Mol Cancer Ther 2009; 8: 2736-2745.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2736-2745
-
-
Bessard, A.1
Sole, V.2
Bouchaud, G.3
Quemener, A.4
Jacques, Y.5
-
17
-
-
42349091974
-
Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells
-
Epardaud M, Elpek KG, Rubinstein MP, Yonekura AR, Bellemare-Pelletier A, Bronson R et al. Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells. Cancer Res 2008; 68: 2972-2983.
-
(2008)
Cancer Res
, vol.68
, pp. 2972-2983
-
-
Epardaud, M.1
Elpek, K.G.2
Rubinstein, M.P.3
Yonekura, A.R.4
Bellemare-Pelletier, A.5
Bronson, R.6
-
18
-
-
42149162887
-
Preassociation of IL-15 with IL-15R alpha-IgG1-Fc enhances its activity on proliferation of NK and CD8(+)/CD44 (high) T cells and its antitumor action
-
Dubois S, Patel HJ, Zhang M, Waldmann TA, Muller JR. Preassociation of IL-15 with IL-15R alpha-IgG1-Fc enhances its activity on proliferation of NK and CD8(+)/CD44 (high) T cells and its antitumor action. J Immunol 2008; 180: 2099-2106.
-
(2008)
J Immunol
, vol.180
, pp. 2099-2106
-
-
Dubois, S.1
Patel, H.J.2
Zhang, M.3
Waldmann, T.A.4
Muller, J.R.5
-
19
-
-
33750335080
-
Combined IL-15/IL-15Ralpha immu-notherapy maximizes IL-15 activity in vivo
-
Stoklasek TA, Schluns KS, Lefrancois L. Combined IL-15/IL-15Ralpha immu-notherapy maximizes IL-15 activity in vivo. J Immunol 2006; 177: 6072-6080.
-
(2006)
J Immunol
, vol.177
, pp. 6072-6080
-
-
Stoklasek, T.A.1
Schluns, K.S.2
Lefrancois, L.3
-
20
-
-
37249000806
-
Efficient systemic expression of bioactive IL-15 in mice upon delivery of optimized DNA expression plasmids
-
Jalah R, Rosati M, Kulkarni V, Patel V, Bergamaschi C, Valentin et al. Efficient systemic expression of bioactive IL-15 in mice upon delivery of optimized DNA expression plasmids. DNA Cell Biol 2007; 26: 827-840.
-
(2007)
DNA Cell Biol
, vol.26
, pp. 827-840
-
-
Jalah, R.1
Rosati, M.2
Kulkarni, V.3
Patel, V.4
Valentin, B.C.5
-
21
-
-
20744443610
-
DNA vaccines expressing different forms of simian immunodeficiency virus antigens decrease viremia upon SIVmac251 challenge
-
Rosati M, von Gegerfelt A, Roth P, Alicea C, Valentin A, Robert-Guroff M et al. DNA vaccines expressing different forms of simian immunodeficiency virus antigens decrease viremia upon SIVmac251 challenge. J Virol 2005; 79: 8480-8492.
-
(2005)
J Virol
, vol.79
, pp. 8480-8492
-
-
Rosati, M.1
Von Gegerfelt, A.2
Roth, P.3
Alicea, C.4
Valentin, A.5
Robert-Guroff, M.6
-
22
-
-
0030960338
-
Inactivation of the human immunodeficiency virus type 1 inhibitory elements allows Rev-independent expression of Gag and Gag/protease and particle formation
-
Schneider R, Campbell M, Nasioulas G, Felber BK, Pavlakis GN. Inactivation of the human immunodeficiency virus type 1 inhibitory elements allows Rev-independent expression of Gag and Gag/protease and particle formation. J Virol 1997; 71: 4892-4903.
-
(1997)
J Virol
, vol.71
, pp. 4892-4903
-
-
Schneider, R.1
Campbell, M.2
Nasioulas, G.3
Felber, B.K.4
Pavlakis, G.N.5
-
23
-
-
0032805251
-
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
-
Liu F, Song Y, Liu D. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther 1999; 6: 1258-1266.
-
(1999)
Gene Ther
, vol.6
, pp. 1258-1266
-
-
Liu, F.1
Song, Y.2
Liu, D.3
-
24
-
-
80054104791
-
Hydrodynamic cell delivery for simultaneous establishment of tumor growth in mouse lung, liver and kidney
-
Li J, Yao Q, Liu D. Hydrodynamic cell delivery for simultaneous establishment of tumor growth in mouse lung, liver and kidney. Cancer Biol Ther 2011; 12: 737-741.
-
(2011)
Cancer Biol Ther
, vol.12
, pp. 737-741
-
-
Li, J.1
Yao, Q.2
Liu, D.3
-
25
-
-
0032534579
-
Combination chemotherapy and IL-15 administration induce permanent tumor regression in a mouse lung tumor model: NK and T cell-mediated effects antagonized by B cells
-
Chapoval AI, Fuller JA, Kremlev SG, Kamdar SJ, Evans R. Combination chemotherapy and IL-15 administration induce permanent tumor regression in a mouse lung tumor model: NK and T cell-mediated effects antagonized by B cells. J Immunol 1998; 161: 6977-6984.
-
(1998)
J Immunol
, vol.161
, pp. 6977-6984
-
-
Chapoval, A.I.1
Fuller, J.A.2
Kremlev, S.G.3
Kamdar, S.J.4
Evans, R.5
-
26
-
-
0035289192
-
Gemcitabine for the treatment of non-small-cell lung cancer
-
Johnson DH. Gemcitabine for the treatment of non-small-cell lung cancer. Oncology (Williston Park) 2001; 15: 33-39.
-
(2001)
Oncology (Williston Park)
, vol.15
, pp. 33-39
-
-
Johnson, D.H.1
-
27
-
-
25144466458
-
Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
-
Suzuki E, Kapoor V, Jassar AS, Kaiser LR, Albelda SM. Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin Cancer Res 2005; 11: 6713-6721.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6713-6721
-
-
Suzuki, E.1
Kapoor, V.2
Jassar, A.S.3
Kaiser, L.R.4
Albelda, S.M.5
-
28
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 2009; 9: 162-174.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
29
-
-
0042914703
-
Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer
-
Yang JC, Sherry RM, Steinberg SM, Topalian SL, Schwartzentruber DJ, Hwu P et al. Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer. J Clin Oncol 2003; 21: 3127-3132.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3127-3132
-
-
Yang, J.C.1
Sherry, R.M.2
Steinberg, S.M.3
Topalian, S.L.4
Schwartzentruber, D.J.5
Hwu, P.6
-
30
-
-
16844379997
-
Immunosuppressive networks in the tumour environment and their therapeutic relevance
-
Zou W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat Rev Cancer 2005; 5: 263-274.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 263-274
-
-
Zou, W.1
-
31
-
-
84876942195
-
Tumor-specific cytotoxic T cells are crucial for efficacy of immunomodulatory antibodies in patients with lung cancer
-
Aerts JG, Hegmans JP. Tumor-specific cytotoxic T cells are crucial for efficacy of immunomodulatory antibodies in patients with lung cancer. Cancer Res 2013; 73: 2381-2388.
-
(2013)
Cancer Res
, vol.73
, pp. 2381-2388
-
-
Aerts, J.G.1
Hegmans, J.P.2
-
32
-
-
78651237278
-
Isolation and characterization of gemcitabine-resistant human non-small cell lung cancer A549 cells
-
Ikeda R, Vermeulen LC, Lau E, Jiang ZS, Sachidanandam K, Yamada K et al. Isolation and characterization of gemcitabine-resistant human non-small cell lung cancer A549 cells. Int J Oncol 2011; 38: 513-519.
-
(2011)
Int J Oncol
, vol.38
, pp. 513-519
-
-
Ikeda, R.1
Vermeulen, L.C.2
Lau, E.3
Jiang, Z.S.4
Sachidanandam, K.5
Yamada, K.6
-
33
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
-
Brahmer J, Reckamp KL, Baas P, Crino L, Eberhardt WEE, Poddubskaya E et al. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Med 2015; 373: 123-135.
-
(2015)
N Engl J Med
, vol.373
, pp. 123-135
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
Crino, L.4
Wee, E.5
Poddubskaya, E.6
|