MicroRNA-126 targeting PIK3R2 promotes rheumatoid arthritis synovial fibro-blasts proliferation and resistance to apoptosis by regulating PI3K/AKT pathway

Experimental and Molecular Pathology

Volumn 100, Issue 1, 2016, Pages 192-198

  Gao, Jie ^a   Zhou, Xiao Li ^b   Kong, Rui Na ^a   Ji, Lian Mei ^a   He, Ling Ling ^a   Zhao, Dong Bao ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b THE AFFILIATED CHANGZHOU NO 2 PEOPLE S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; MicroRNA 126; PI3K AKT signaling pathway; PIK3R2; Proliferation; Rheumatoid arthritis; Synovial fibro blasts

Indexed keywords

MESSENGER RNA; MICRORNA 126; PHOSPHATIDYLINOSITOL 3 KINASE; PIK3R2 PROTEIN; PROTEIN KINASE B; REGULATOR PROTEIN; UNCLASSIFIED DRUG; MICRORNA; MIRN126 MICRORNA, HUMAN; PHOSPHOINOSITOL-3 KINASE REGULATORY SUBUNIT 2, HUMAN;

ADULT; AGED; APOPTOSIS; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; FIBROBLAST; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PIK3R2 GENE; PROTEIN EXPRESSION; REGULATOR GENE; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIOCYTE; SYNOVIUM; DOWN REGULATION; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; YOUNG ADULT;

ADULT; AGED; APOPTOSIS; ARTHRITIS, RHEUMATOID; CELL PROLIFERATION; DOWN-REGULATION; FEMALE; FIBROBLASTS; HUMANS; MALE; MICRORNAS; MIDDLE AGED; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; YOUNG ADULT;

EID: 84953409976     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2015.12.015     Document Type: Article

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