Multifunctional PLGA nanobubbles as theranostic agents: Combining doxorubicin and P-gp siRNA co-delivery into human breast cancer cells and ultrasound cellular imaging

Journal of Biomedical Nanotechnology

Volumn 11, Issue 12, 2015, Pages 2124-2136

  Yang, Hong ^a   Deng, Liwei ^a   Li, Tingting ^a   Shen, Xue ^a   Yan, Jie ^a   Zuo, Liangming ^b   Wu, Chunhui ^a   Liu, Yiyao ^a  

^a UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b Affiliated Cancer Hospital of University of Electronic Science and Technology of China   (China)

Author keywords

Co delivery; Doxorubicin; Nanobubbles; P gp gene silence; PLGA; Ultrasound imaging

Indexed keywords

CELL CULTURE; CELL PROLIFERATION; CHEMOTHERAPY; CONTROLLED DRUG DELIVERY; DISEASES; FLUORESCENCE; FLUORESCENCE MICROSCOPY; GENES; GENETIC ENGINEERING; GLYCOPROTEINS; MEDICAL IMAGING; ULTRASONIC IMAGING;

CO DELIVERIES; DOXORUBICIN; GENE SILENCE; NANOBUBBLES; PLGA; ULTRASOUND IMAGING;

TARGETED DRUG DELIVERY;

CHLORPROMAZINE; CYTOCHALASIN D; DOXORUBICIN; MULTIDRUG RESISTANCE PROTEIN; NANOBUBBLE; POLYETHYLENEIMINE; POLYGLACTIN; SHORT HAIRPIN RNA; ANTINEOPLASTIC AGENT; CONTRAST MEDIUM; DRUG CARRIER; LACTIC ACID; NANOMATERIAL; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; SMALL INTERFERING RNA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER RESISTANCE; CELL PROLIFERATION; CELL VIABILITY; COMPARATIVE STUDY; COMPLEX FORMATION; CONTROLLED STUDY; CROSS LINKING; DOWN REGULATION; DRUG BIOAVAILABILITY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG STABILITY; ECHOGRAPHY; ENDOCYTOSIS; FLUORESCENCE MICROSCOPY; GENE SILENCING; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; INTERNALIZATION; INTRACELLULAR TRANSPORT; MCF 7 CELL LINE; MOLECULAR IMAGING; NANOENCAPSULATION; PH; PHYSICAL CHEMISTRY; PINOCYTOSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SPECTROFLUOROMETRY; STATIC ELECTRICITY; SURFACE CHARGE; ZETA POTENTIAL; BREAST TUMOR; CHEMISTRY; DEFICIENCY; DRUG EFFECTS; DRUG RESISTANCE; GENETICS; INTRACELLULAR SPACE; METABOLISM; PATHOLOGY; RNA INTERFERENCE;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CONTRAST MEDIA; DOXORUBICIN; DRUG CARRIERS; DRUG LIBERATION; DRUG RESISTANCE, NEOPLASM; ENDOCYTOSIS; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR SPACE; LACTIC ACID; MCF-7 CELLS; NANOSTRUCTURES; P-GLYCOPROTEIN; POLYGLYCOLIC ACID; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84953343414     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2015.2168     Document Type: Article

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