-
1
-
-
77950261786
-
Improved survival in systemic sclerosis is associated with better ascertainment of internal organ disease: a retrospective cohort study
-
NIHTYANOVA SI, TANG EC, COGHLAN JG, WELLS AU, BLACK CM, DENTON CP: Improved survival in systemic sclerosis is associated with better ascertainment of internal organ disease: a retrospective cohort study. QJM 2010; 103: 109-15.
-
(2010)
QJM
, vol.103
, pp. 109-115
-
-
Nihtyanova, S.I.1
Tang, E.C.2
Coghlan, J.G.3
Wells, A.U.4
Black, C.M.5
Denton, C.P.6
-
3
-
-
84881138875
-
Targeted therapies for systemic sclerosis
-
DENTON CP, ONG VH: Targeted therapies for systemic sclerosis. Nat Rev Rheumatol 2013; 9: 451-64.
-
(2013)
Nat Rev Rheumatol
, vol.9
, pp. 451-464
-
-
Denton, C.P.1
Ong, V.H.2
-
4
-
-
84902844800
-
Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial
-
van LAAR JM, FARGE D, SONT JK et al.: EBMT/EULAR Scleroderma Study Group. Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial. JAMA 2014; 311: 2490-8.
-
(2014)
JAMA
, vol.311
, pp. 2490-2498
-
-
Van Laar, J.M.1
Farge, D.2
Sont, J.K.3
-
5
-
-
84898775777
-
Prediction of pulmonary complications and long-term survival in systemic sclerosis
-
NIHTYANOVA SI, SCHREIBER BE, ONG VH et al.: Prediction of pulmonary complications and long-term survival in systemic sclerosis. Arthritis Rheum 2014; 66: 1625-35.
-
(2014)
Arthritis Rheum
, vol.66
, pp. 1625-1635
-
-
Nihtyanova, S.I.1
Schreiber, B.E.2
Ong, V.H.3
-
6
-
-
84896506258
-
Groupe Français de Recherche sur la Sclérodermie. Clinical, functional and health-related quality of life correlates of clinically significant symptoms of anxiety and depression in patients with systemic sclerosis: a cross-sectional survey
-
NGUYEN C, RANQUE B, BAUBET T et al.: Groupe Français de Recherche sur la Sclérodermie. Clinical, functional and health-related quality of life correlates of clinically significant symptoms of anxiety and depression in patients with systemic sclerosis: a cross-sectional survey. PLoS One 2014; 9: e90484.
-
(2014)
PLoS One
, vol.9
-
-
Nguyen, C.1
Ranque, B.2
Baubet, T.3
-
7
-
-
84898799747
-
Current management strategies for systemic sclerosis
-
NIHTYANOVA SI, ONG VH, DENTON CP: Current management strategies for systemic sclerosis. Clin Exp Rheumatol 2014; 32 (Suppl. 81): 156-64.
-
(2014)
Clin Exp Rheumatol
, vol.32
, pp. 156-164
-
-
Nihtyanova, S.I.1
Ong, V.H.2
Denton, C.P.3
-
8
-
-
84928719391
-
Twenty-two points to consider for clinical trials in systemic sclerosis, based on EULAR standards?
-
KHANNA D, FURST DE, ALLANORE Y et al.: Twenty-two points to consider for clinical trials in systemic sclerosis, based on EULAR standards. Rheumatology 2015; 54; 144-51.
-
(2015)
Rheumatology
, vol.54
, pp. 144-151
-
-
Khanna, D.1
Furst, D.E.2
Allanore, Y.3
-
9
-
-
73649119523
-
Observational study of treatment outcome in early diffuse cutaneous systemic sclerosis
-
HERRICK AL, LUNT M, WHIDBY N et al.: Observational study of treatment outcome in early diffuse cutaneous systemic sclerosis. J Rheumatol 2010; 37: 116-24.
-
(2010)
J Rheumatol
, vol.37
, pp. 116-124
-
-
Herrick, A.L.1
Lunt, M.2
Whidby, N.3
-
10
-
-
76649085510
-
Autoantibodies as predictive tools in systemic sclerosis
-
NIHTYANOVA SI, DENTON CP: Autoantibodies as predictive tools in systemic sclerosis. Nat Rev Rheumatol 2010; 6: 112-6.
-
(2010)
Nat Rev Rheumatol
, vol.6
, pp. 112-116
-
-
Nihtyanova, S.I.1
Denton, C.P.2
-
11
-
-
84899925204
-
Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability
-
DISTLER A, LANG V, DEL VECCHIO T et al.: Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability. Ann Rheum Dis 2014; 73: 1264-8.
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 1264-1268
-
-
Distler, A.1
Lang, V.2
Del Vecchio, T.3
-
12
-
-
70349826650
-
Animal models of scleroderma: lessons from transgenic and knockout mice
-
DERRETT-SMITH EC, DENTON CP, SONNYLAL S: Animal models of scleroderma: lessons from transgenic and knockout mice. Curr Opin Rheumatol 2009; 21: 630-5.
-
(2009)
Curr Opin Rheumatol
, vol.21
, pp. 630-635
-
-
Derrett-Smith, E.C.1
Denton, C.P.2
Sonnylal, S.3
-
13
-
-
42449125545
-
Fibroblast-specific perturbation of transforming growth factor beta signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: exaggerated response to alveolar epithelial injury in a novel mouse model
-
HOYLES RK, KHAN K, SHIWEN X et al.: Fibroblast-specific perturbation of transforming growth factor beta signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: exaggerated response to alveolar epithelial injury in a novel mouse model. Arthritis Rheum 2008; 58: 1175-88.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1175-1188
-
-
Hoyles, R.K.1
Khan, K.2
Shiwen, X.3
-
14
-
-
84886801549
-
Endothelial injury in a transforming growth factor β-dependent mouse model of scleroderma induces pulmonary arterial hypertension
-
DERRETT-SMITH EC, DOOLEY A, GILBANE AJ et al.: Endothelial injury in a transforming growth factor β-dependent mouse model of scleroderma induces pulmonary arterial hypertension. Arthritis Rheum 2013; 65: 2928-39.
-
(2013)
Arthritis Rheum
, vol.65
, pp. 2928-2939
-
-
Derrett-Smith, E.C.1
Dooley, A.2
Gilbane, A.J.3
-
15
-
-
84924758403
-
Impaired bone morphogenetic protein receptor II signaling in a transforming growth factor-β-dependent mouse model of pulmonary hypertension and in systemic sclerosis
-
GILBANE AJ, DERRETT-SMITH E, TRINDER SL et al.: Impaired bone morphogenetic protein receptor II signaling in a transforming growth factor-β-dependent mouse model of pulmonary hypertension and in systemic sclerosis. Am J Respir Crit Care Med 2015; 191: 665-77.
-
(2015)
Am J Respir Crit Care Med
, vol.191
, pp. 665-677
-
-
Gilbane, A.J.1
Derrett-Smith, E.2
Trinder, S.L.3
-
16
-
-
33846250366
-
Recombinant human anti-transforming growth factor beta1 antibody therapy in systemic sclerosis: a multicenter, randomized, placebo-controlled phase I/II trial of CAT-192
-
DENTON CP, MERKEL PA, FURST DE et al.: Recombinant human anti-transforming growth factor beta1 antibody therapy in systemic sclerosis: a multicenter, randomized, placebo-controlled phase I/II trial of CAT-192. Arthritis Rheum 2007; 56: 323-33.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 323-333
-
-
Denton, C.P.1
Merkel, P.A.2
Furst, D.E.3
-
17
-
-
84936791793
-
Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients
-
RICE LM, PADILLA CM, McLAUGHLIN SR et al.: Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients. J Clin Invest 2015; 125: 2795-807.
-
(2015)
J Clin Invest
, vol.125
, pp. 2795-2807
-
-
Rice, L.M.1
Padilla, C.M.2
Mclaughlin, S.R.3
-
18
-
-
84889677536
-
Treatment of diffuse systemic sclerosis with hyperimmune caprine serum (AIMSPRO): a phase II double-blind placebo-controlled trial
-
QUILLINAN NP, McINTOSH D, VERNES J, HAQ S, DENTON CP: Treatment of diffuse systemic sclerosis with hyperimmune caprine serum (AIMSPRO): a phase II double-blind placebo-controlled trial. Ann Rheum Dis 2014; 73: 56-61.
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 56-61
-
-
Quillinan, N.P.1
Mcintosh, D.2
Vernes, J.3
Haq, S.4
Denton, C.P.5
-
19
-
-
84868331821
-
Autotaxin emerges as a therapeutic target for idiopathic pulmonary fibrosis: limiting fibrosis by limiting lysophosphatidic acid synthesis
-
TAGER AM: Autotaxin emerges as a therapeutic target for idiopathic pulmonary fibrosis: limiting fibrosis by limiting lysophosphatidic acid synthesis. Am J Respir Cell Mol Biol 2012; 47: 563-5.
-
(2012)
Am J Respir Cell Mol Biol
, vol.47
, pp. 563-565
-
-
Tager, A.M.1
-
20
-
-
79955559412
-
Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma
-
CASTELINO FV, SEIDERS J, BAIN G et al.: Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma. Arthritis Rheum 2011; 63: 1405-15.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1405-1415
-
-
Castelino, F.V.1
Seiders, J.2
Bain, G.3
-
21
-
-
38049091636
-
The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak
-
TAGER AM, LACAMERA P, SHEA BS et al.: The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak. Nat Med 2008; 14: 45-54.
-
(2008)
Nat Med
, vol.14
, pp. 45-54
-
-
Tager, A.M.1
Lacamera, P.2
Shea, B.S.3
-
22
-
-
84875861264
-
Serum interleukin 6 is predictive of early functional decline and mortality in interstitial lung disease associated with systemic sclerosis
-
de LAURETIS A, SESTINI P, PANTELIDIS P et al.: Serum interleukin 6 is predictive of early functional decline and mortality in interstitial lung disease associated with systemic sclerosis. J Rheumatol 2013; 40: 435-46.
-
(2013)
J Rheumatol
, vol.40
, pp. 435-446
-
-
De Lauretis, A.1
Sestini, P.2
Pantelidis, P.3
-
23
-
-
84862520877
-
Clinical and pathological significance of interleukin 6 overexpression in systemic sclerosis
-
KHAN K, XU S, NIHTYANOVA S et al.: Clinical and pathological significance of interleukin 6 overexpression in systemic sclerosis. Ann Rheum Dis 2012; 71: 1235-42.
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 1235-1242
-
-
Khan, K.1
Xu, S.2
Nihtyanova, S.3
-
24
-
-
84887463104
-
Levels of target activation predict antifibrotic responses to tyrosine kinase inhibitors
-
MAURER B, DISTLER A, DEES C et al.: Levels of target activation predict antifibrotic responses to tyrosine kinase inhibitors. Ann Rheum Dis 2013; 72: 2039-46.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 2039-2046
-
-
Maurer, B.1
Distler, A.2
Dees, C.3
-
25
-
-
84865814629
-
Severe interstitial lung disease in connective tissue disease: rituximab as rescue therapy
-
KEIR GJ, MAHER TM, HANSELL DM et al.: Severe interstitial lung disease in connective tissue disease: rituximab as rescue therapy. Eur Respir J 2012; 40: 641-8.
-
(2012)
Eur Respir J
, vol.40
, pp. 641-648
-
-
Keir, G.J.1
Maher, T.M.2
Hansell, D.M.3
-
26
-
-
84925537240
-
Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis
-
PLUMBO-ZERR K, ZERR P, DISTLER A et al.: Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis. Nat Med 2015; 21: 150-8.
-
(2015)
Nat Med
, vol.21
, pp. 150-158
-
-
Plumbo-Zerr, K.1
Zerr, P.2
Distler, A.3
|