Insulin-like growth factor 1 receptor expression and IGF1R 3129G > T polymorphism are associated with response to neoadjuvant chemotherapy in breast cancer patients: Results from the NEOZOTAC trial (BOOG 2010-01)

Breast Cancer Research

Volumn 18, Issue 1, 2016, Pages

  de Groot, Stefanie ^a   Charehbili, Ayoub ^a   van Laarhoven, Hanneke W M ^b   Mooyaart, Antien L ^a   Dekker Ensink, N Geeske ^a   van de Ven, Saskia ^c   Janssen, Laura G M ^a   Swen, Jesse J ^a   Smit, Vincent T H B M ^a   Heijns, Joan B ^d   Kessels, Lonneke W ^e   van der Straaten, Tahar ^a   Böhringer, Stefan ^a   Gelderblom, Hans ^a   van der Hoeven, Jacobus J M ^a   Guchelaar, Henk Jan ^a   Pijl, Hanno ^a   Kroep, Judith R ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d AMPHIA HOSPITAL   (Netherlands)

^e DEVENTER HOSPITAL   (Netherlands)

Author keywords

Breast cancer; Glucose; IGF 1; IGF 1R; IGF BP3; Insulin; Miller and payne; Neoadjuvant chemotherapy; Pathological complete response; Single nucleotide polymorphisms

Indexed keywords

CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; SOMATOMEDIN B; SOMATOMEDIN C RECEPTOR; ZOLEDRONIC ACID; ANTINEOPLASTIC AGENT; IGF1R PROTEIN, HUMAN; SOMATOMEDIN RECEPTOR; TUMOR MARKER;

ADJUVANT CHEMOTHERAPY; ADULT; AGED; ALLELE; ARTICLE; BREAST BIOPSY; BREAST CANCER; CANCER PATIENT; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG RESPONSE; FEMALE; HUMAN; HUMAN TISSUE; IGF1 GENE; IGF1R GENE; IGF2 GENE; IGFBP3 GENE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MULTICENTER STUDY (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; UPREGULATION; BIOSYNTHESIS; BREAST NEOPLASMS; CLINICAL TRIAL; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION STUDY; GENETICS; MIDDLE AGED; NEOADJUVANT THERAPY; PATHOLOGY; PHASE 3 CLINICAL TRIAL; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BIOMARKERS, TUMOR; BREAST NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC ASSOCIATION STUDIES; HUMANS; MIDDLE AGED; NEOADJUVANT THERAPY; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; RECEPTORS, SOMATOMEDIN;

EID: 84953298852     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/s13058-015-0663-3     Document Type: Article

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