African Glucose-6-Phosphate Dehydrogenase Alleles Associated with Protection from Severe Malaria in Heterozygous Females in Tanzania

PLoS Genetics

Volumn 11, Issue 2, 2015, Pages

  Manjurano, Alphaxard ^a   Sepulveda, Nuno ^b   Nadjm, Behzad ^b,d   Mtove, George ^a   Wangai, Hannah ^a   Maxwell, Caroline ^a   Olomi, Raimos ^a   Reyburn, Hugh ^a,b   Riley, Eleanor M ^a,b   Drakeley, Christopher J ^a,b   Clark, Taane G ^b  

^a KILIMANJARO CHRISTIAN MEDICAL UNIVERSITY COLLEGE   (Tanzania)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GENETIC MARKER;

AFRICAN; ALLELE; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME POLYMORPHISM; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC MARKER; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; HAPLOTYPE; HETEROZYGOTE; HUMAN; INFECTION RESISTANCE; MAJOR CLINICAL STUDY; MALARIA; PRESCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; TANZANIA; GENETIC SELECTION; GENETICS; INFANT; MALE; PARASITOLOGY; PATHOLOGY; POPULATION GENETICS; X CHROMOSOME;

ALLELES; CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, X; FEMALE; GENE FREQUENCY; GENETIC MARKERS; GENETICS, POPULATION; GLUCOSEPHOSPHATE DEHYDROGENASE; HAPLOTYPES; HETEROZYGOTE; HUMANS; INFANT; MALARIA; MALE; SELECTION, GENETIC; TANZANIA;

EID: 84938803802     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004960     Document Type: Article

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