Elevated IL-33 expression is associated with pediatric eosinophilic esophagitis, and exogenous IL-33 promotes eosinophilic esophagitis development in mice

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 310, Issue 1, 2016, Pages G13-G25

  Judd, L M ^a,b   Heine, R G ^a   Menheniott, T R ^a   Buzzelli, J ^a   O'Brien Simpson N ^c   Pavlic, D ^a   O'Connor L ^a   Al Gazali, K ^a   Hamilton, O ^a   Scurr, M ^a   Collison, A M ^d   Mattes, J ^d   Allen, K J ^a,b   Giraud, A S ^a  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d HUNTER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Eosinophilic esophagitis; Food allergy; IL 33; Th2

Indexed keywords

AMPHIREGULIN; EOTAXIN 2; GAMMA INTERFERON; INDUCIBLE T CELL COSTIMULATOR; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 33; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 9; MESSENGER RNA; SMAD7 PROTEIN; SOMATOMEDIN; THYMIC STROMAL LYMPHOPOIETIN; TRANSFORMING GROWTH FACTOR BETA; AUTACOID; BETA CHEMOKINE; CCL26 PROTEIN, HUMAN; IL33 PROTEIN, HUMAN; IL33 PROTEIN, MOUSE; INTERLEUKIN 13;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CHILD; CHILDHOOD DISEASE; CHRONICITY; CONTROLLED STUDY; DISEASE ASSOCIATION; EOSINOPHILIC ESOPHAGITIS; EPITHELIUM CELL; ESOPHAGUS BIOPSY; ESOPHAGUS MUCOSA; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LYMPHOID CELL; MARKER GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SCHOOL CHILD; TH1 CELL; TH17 CELL; TH2 CELL; UPREGULATION; ADOLESCENT; ANIMAL; ASPERGILLUS FUMIGATUS; BAGG ALBINO MOUSE; BIOPSY; CASE CONTROL STUDY; CELL PROLIFERATION; CHEMICALLY INDUCED; DEFICIENCY; DISEASE MODEL; ENDOTHELIUM CELL; ESOPHAGUS; GENETICS; HELPER CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; INNATE IMMUNITY; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; PHENOTYPE; PRESCHOOL CHILD; TIME FACTOR;

ADAPTIVE IMMUNITY; ADOLESCENT; ANIMALS; ASPERGILLUS FUMIGATUS; BIOPSY; CASE-CONTROL STUDIES; CELL PROLIFERATION; CHEMOKINES, CC; CHILD; CHILD, PRESCHOOL; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; EOSINOPHILIC ESOPHAGITIS; ESOPHAGUS; HUMANS; IMMUNE TOLERANCE; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; INTERLEUKIN-13; INTERLEUKIN-33; MACROPHAGES; MICE, INBRED BALB C; MICE, KNOCKOUT; PHENOTYPE; RNA, MESSENGER; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY; TIME FACTORS; UP-REGULATION;

EID: 84953269160     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00290.2015     Document Type: Article

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