Erratum: GDNF Overexpression from the Native Locus Reveals its Role in the Nigrostriatal Dopaminergic System Function (PLoS Genetics (2015) 11:12 (e1005710) DOI: 10.1371/journal.pgen.1005710);GDNF Overexpression from the Native Locus Reveals its Role in the Nigrostriatal Dopaminergic System Function

PLoS Genetics

Volumn 11, Issue 12, 2015, Pages

  Kumar, Anmol ^a   Kopra, Jaakko ^b   Varendi, Kärt ^a   Porokuokka, Lauriina L ^a   Panhelainen, Anne ^a   Kuure, Satu ^a   Marshall, Pepin ^a   Karalija, Nina ^c   Härma, Mari Anne ^a   Vilenius, Carolina ^a   Lilleväli, Kersti ^d   Tekko, Triin ^d   Mijatovic, Jelena ^b   Pulkkinen, Nita ^b   Jakobson, Madis ^e   Jakobson, Maili ^a   Ola, Roxana ^e   Palm, Erik ^a   Lindahl, Maria ^a   Strömberg, Ingrid ^c   Võikar, Vootele ^b   Piepponen, T Petteri ^b   Saarma, Mart ^a   Andressoo, Jaan Olle ^a   more..

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UMEÅ UNIVERSITY   (Sweden)

^d UNIVERSITY OF TARTU   (Estonia)

^e UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; LACTACYSTIN; MICRORNA; MICRORNA 133; MICRORNA 146A; MICRORNA 9; MICRORNA 96; UNCLASSIFIED DRUG; ACETYLCYSTEINE; GDNF PROTEIN, MOUSE; NEUROPROTECTIVE AGENT;

3' UNTRANSLATED REGION; ADULT; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM FUNCTION; CONTROLLED STUDY; CORPUS STRIATUM; CYCLIC POTENTIOMETRY; DOPAMINE RELEASE; DOPAMINE UPTAKE; DOPAMINERGIC NERVE CELL; DOPAMINERGIC SYSTEM; GDNF GENE; GENE LOCUS; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; IN SITU HYBRIDIZATION; IN VITRO STUDY; MALE; MOUSE; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PROTEIN FUNCTION; SUBSTANTIA NIGRA PARS COMPACTA; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; BIOSYNTHESIS; CENTRAL NERVOUS SYSTEM; CHEMICALLY INDUCED; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; KIDNEY; METABOLISM; NEOSTRIATUM; PATHOLOGY; SUBSTANTIA NIGRA;

ACETYLCYSTEINE; ANIMALS; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; DOPAMINE; DOPAMINERGIC NEURONS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HUMANS; KIDNEY; MICE; NEOSTRIATUM; NEUROPROTECTIVE AGENTS; PARKINSON DISEASE, SECONDARY; SUBSTANTIA NIGRA;

EID: 84953258846     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/JOURNAL.PGEN.1005808     Document Type: Erratum

References (47)

1. Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F, (1993) GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260: 1130–1132. 8493557
2. Hoffer BJ, Hoffman A, Bowenkamp K, Huettl P, Hudson J, et al. (1994) Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo. Neurosci Lett 182: 107–111. 7891873
3. Meissner WG, Frasier M, Gasser T, Goetz CG, Lozano A, et al. (2011) Priorities in Parkinson's disease research. Nat Rev Drug Discov 10: 377–393. doi: 10.1038/nrd3430 21532567
4. Georgievska B, Kirik D, Bjorklund A, (2002) Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer. Exp Neurol 177: 461–474. 12429192
5. Georgievska B, Kirik D, Bjorklund A, (2004) Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time- and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system. J Neurosci 24: 6437–6445. 15269253
6. Manfredsson FP, Tumer N, Erdos B, Landa T, Broxson CS, et al. (2009) Nigrostriatal rAAV-mediated GDNF overexpression induces robust weight loss in a rat model of age-related obesity. Mol Ther 17: 980–991. doi: 10.1038/mt.2009.45 19277011
7. Airaksinen MS, Saarma M, (2002) The GDNF family: signalling, biological functions and therapeutic value. Nat Rev Neurosci 3: 383–394. 11988777
8. Kholodilov N, Yarygina O, Oo TF, Zhang H, Sulzer D, et al. (2004) Regulation of the development of mesencephalic dopaminergic systems by the selective expression of glial cell line-derived neurotrophic factor in their targets. J Neurosci 24: 3136–3146. 15044553
9. Pascual A, Hidalgo-Figueroa M, Piruat JI, Pintado CO, Gomez-Diaz R, et al. (2008) Absolute requirement of GDNF for adult catecholaminergic neuron survival. Nat Neurosci.
10. Kopra J, Vilenius C, Grealish S, Harma MA, Varendi K, et al. (2015) GDNF is not required for catecholaminergic neuron survival in vivo. Nat Neurosci 18: 319–322. doi: 10.1038/nn.3941 25710828
11. Oh-Hashi K, Hirata Y, Kiuchi K, (2012) Characterization of 3'-untranslated region of the mouse GDNF gene. BMC Mol Biol 13: 2. doi: 10.1186/1471-2199-13-2 22248285
12. Chen YT, Bradley A, (2000) A new positive/negative selectable marker, puDeltatk, for use in embryonic stem cells. Genesis 28: 31–35. 11020714
13. Kramer ER, Knott L, Su F, Dessaud E, Krull CE, et al. (2006) Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb. Neuron 50: 35–47. 16600854
14. Meng X, Lindahl M, Hyvonen ME, Parvinen M, de Rooij DG, et al. (2000) Regulation of cell fate decision of undifferentiated spermatogonia by GDNF. Science 287: 1489–1493. 10688798
15. Pichel JG, Shen L, Sheng HZ, Granholm AC, Drago J, et al. (1996) Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 382: 73–76. 8657307
16. Sainio K, Suvanto P, Davies J, Wartiovaara J, Wartiovaara K, et al. (1997) Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium. Development 124: 4077–4087. 9374404
17. Hidalgo-Figueroa M, Bonilla S, Gutierrez F, Pascual A, Lopez-Barneo J, (2012) GDNF Is Predominantly Expressed in the PV+ Neostriatal Interneuronal Ensemble in Normal Mouse and after Injury of the Nigrostriatal Pathway. J Neurosci 32: 864–872. doi: 10.1523/JNEUROSCI.2693-11.2012 22262884
18. Blum M, Weickert CS, (1995) GDNF mRNA expression in normal postnatal development, aging, and in Weaver mutant mice. Neurobiol Aging 16: 925–929. 8622783
19. Trupp M, Belluardo N, Funakoshi H, Ibanez CF, (1997) Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS. J Neurosci 17: 3554–3567. 9133379
20. Wang F, Flanagan J, Su N, Wang LC, Bui S, et al. (2012) RNAscope: a novel in situ RNA analysis platform for formalin-fixed, paraffin-embedded tissues. J Mol Diagn 14: 22–29. doi: 10.1016/j.jmoldx.2011.08.002 22166544
21. Airavaara M, Mijatovic J, Vihavainen T, Piepponen TP, Saarma M, et al. (2006) In heterozygous GDNF knockout mice the response of striatal dopaminergic system to acute morphine is altered. Synapse 59: 321–329. 16437537
22. Sulzer D, Chen TK, Lau YY, Kristensen H, Rayport S, et al. (1995) Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport. J Neurosci 15: 4102–4108. 7751968
23. Westerlund M, Hoffer B, Olson L, (2010) Parkinson's disease: Exit toxins, enter genetics. Prog Neurobiol 90: 146–156. doi: 10.1016/j.pneurobio.2009.11.001 19925845
24. Bentea E, Van der Perren A, Van Liefferinge J, El Arfani A, Albertini G, et al. (2015) Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated alpha-synuclein. Front Behav Neurosci 9: 68. doi: 10.3389/fnbeh.2015.00068 25873870
25. Matsui H, Ito H, Taniguchi Y, Inoue H, Takeda S, et al. (2010) Proteasome inhibition in medaka brain induces the features of Parkinson's disease. J Neurochem 115: 178–187. doi: 10.1111/j.1471-4159.2010.06918.x 20649841
26. Hudson J, Granholm AC, Gerhardt GA, Henry MA, Hoffman A, et al. (1995) Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo. Brain Res Bull 36: 425–432. 7712205
27. Hebert MA, Gerhardt GA, (1997) Behavioral and neurochemical effects of intranigral administration of glial cell line-derived neurotrophic factor on aged Fischer 344 rats. J Pharmacol Exp Ther 282: 760–768. 9262339
28. Hebert MA, Van Horne CG, Hoffer BJ, Gerhardt GA, (1996) Functional effects of GDNF in normal rat striatum: presynaptic studies using in vivo electrochemistry and microdialysis. J Pharmacol Exp Ther 279: 1181–1190. 8968339
29. Emerich DF, Plone M, Francis J, Frydel BR, Winn SR, et al. (1996) Alleviation of behavioral deficits in aged rodents following implantation of encapsulated GDNF-producing fibroblasts. Brain Res 736: 99–110. 8930314
30. Rosenblad C, Georgievska B, Kirik D, (2003) Long-term striatal overexpression of GDNF selectively downregulates tyrosine hydroxylase in the intact nigrostriatal dopamine system. Eur J Neurosci 17: 260–270. 12542662
31. Kumar A, Varendi K, Peranen J, Andressoo JO, (2014) Tristetraprolin is a novel regulator of BDNF. Springerplus 3: 502. doi: 10.1186/2193-1801-3-502 25279294
32. Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, et al. (2007) A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129: 1401–1414. 17604727
33. John B, Enright AJ, Aravin A, Tuschl T, Sander C, et al. (2004) Human MicroRNA targets. PLoS Biol 2: e363. 15502875
34. Wen J, Parker BJ, Jacobsen A, Krogh A, (2011) MicroRNA transfection and AGO-bound CLIP-seq data sets reveal distinct determinants of miRNA action. RNA 17: 820–834. doi: 10.1261/rna.2387911 21389147
35. Harfe BD, McManus MT, Mansfield JH, Hornstein E, Tabin CJ, (2005) The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc Natl Acad Sci U S A 102: 10898–10903. 16040801
36. Shakya R, Jho EH, Kotka P, Wu Z, Kholodilov N, et al. (2005) The role of GDNF in patterning the excretory system. Dev Biol 283: 70–84. 15890330
37. Parish CL, Finkelstein DI, Drago J, Borrelli E, Horne MK, (2001) The role of dopamine receptors in regulating the size of axonal arbors. J Neurosci 21: 5147–5157. 11438590
38. Kowsky S, Poppelmeyer C, Kramer ER, Falkenburger BH, Kruse A, et al. (2007) RET signaling does not modulate MPTP toxicity but is required for regeneration of dopaminergic axon terminals. Proc Natl Acad Sci U S A 104: 20049–20054. 18056810
39. Du Y, Zhang X, Tao Q, Chen S, Le W, (2013) Adeno-associated virus type 2 vector-mediated glial cell line-derived neurotrophic factor gene transfer induces neuroprotection and neuroregeneration in a ubiquitin-proteasome system impairment animal model of Parkinson's disease. Neurodegener Dis 11: 113–128. doi: 10.1159/000334527 22626907
40. Love S, Plaha P, Patel NK, Hotton GR, Brooks DJ, et al. (2005) Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain. Nat Med 11: 703–704. 16015352
41. Smith-Hicks CL, Sizer KC, Powers JF, Tischler AS, Costantini F, (2000) C-cell hyperplasia, pheochromocytoma and sympathoadrenal malformation in a mouse model of multiple endocrine neoplasia type 2B. Embo J 19: 612–622. 10675330
42. Mijatovic J, Piltonen M, Alberton P, Mannisto PT, Saarma M, et al. (2009) Constitutive Ret signaling is protective for dopaminergic cell bodies but not for axonal terminals. Neurobiol Aging.
43. Mijatovic J, Airavaara M, Planken A, Auvinen P, Raasmaja A, et al. (2007) Constitutive Ret activity in knock-in multiple endocrine neoplasia type B mice induces profound elevation of brain dopamine concentration via enhanced synthesis and increases the number of TH-positive cells in the substantia nigra. J Neurosci 27: 4799–4809. 17475787
44. Mijatovic J, Patrikainen O, Yavich L, Airavaara M, Ahtee L, et al. (2008) Characterization of the striatal dopaminergic neurotransmission in MEN2B mice with elevated cerebral tissue dopamine. J Neurochem 105: 1716–1725. doi: 10.1111/j.1471-4159.2008.05265.x 18248620
45. Varendi K, Matlik K, Andressoo JO, (2015) From microRNA target validation to therapy: lessons learned from studies on BDNF. Cell Mol Life Sci.
46. Vasudevan S, (2012) Posttranscriptional upregulation by microRNAs. Wiley Interdiscip Rev RNA 3: 311–330. doi: 10.1002/wrna.121 22072587
47. van der Weyden L, Adams DJ, Harris LW, Tannahill D, Arends MJ, et al. (2005) Null and conditional Semaphorin 3B alleles using a flexible puro Delta tk LoxP/FRT vector. Genesis 41: 171–178. 15789413