Mechanism of Iron-Dependent Repressor (IdeR) Activation and DNA Binding: A Molecular Dynamics and Protein Structure Network Study

PLoS Computational Biology

Volumn 11, Issue 12, 2015, Pages

  Ghosh, Soma ^a   Chandra, Nagasuma ^a   Vishveshwara, Saraswathi ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BIOINFORMATICS; CHEMICAL ACTIVATION; COMPLEX NETWORKS; DNA; METAL IONS; MOLECULAR DYNAMICS; PROTEINS; REACTION KINETICS; REDOX REACTIONS; SIGNAL TRANSDUCTION;

BIOLOGICAL FUNCTIONS; DNA COMPLEX; DNA-BINDING; DYNAMIC STRUCTURE; IRON CONCENTRATIONS; LIVING SYSTEMS; METAL SENSING; METALLO-PROTEINS; PROTEINS STRUCTURES; STRUCTURE NETWORK;

IRON;

IRON DEPENDENT REPRESSOR; MONOMER; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; DNA; IDER PROTEIN, MYCOBACTERIUM TUBERCULOSIS; PROTEIN BINDING; REPRESSOR PROTEIN;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; DIMERIZATION; DISSOCIATION; DNA BINDING; DNA PROTEIN COMPLEX; MOLECULAR DYNAMICS; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN SUBUNIT; SIMULATION; STRUCTURE ACTIVITY RELATION; BINDING SITE; CHEMICAL MODEL; CHEMISTRY; CONFORMATION; ENZYME ACTIVATION; ENZYME SPECIFICITY; KINETICS; PROTEIN CONFORMATION; ULTRASTRUCTURE;

BACTERIAL PROTEINS; BINDING SITES; DNA; ENZYME ACTIVATION; KINETICS; MODELS, CHEMICAL; MOLECULAR DYNAMICS SIMULATION; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; REPRESSOR PROTEINS; SUBSTRATE SPECIFICITY;

EID: 84953238191     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004500     Document Type: Article

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