Identifying Family-Member-Specific Targets of Mono-ARTDs by Using a Chemical Genetics Approach

Cell Reports

Volumn 14, Issue 3, 2016, Pages 621-631

  Carter O'Connell, Ian ^a   Jin, Haihong ^a   Morgan, Rory K ^a   Zaja, Roko ^b   David, Larry L ^a   Ahel, Ivan ^b   Cohen, Michael S ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTD10 PROTEIN; ARTD11 PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; UNCLASSIFIED DRUG; PROTEIN SERINE THREONINE KINASE; SRPK2 PROTEIN, HUMAN;

ADENOSINE DIPHOSPHATE RIBOSYLATION; AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL GENETICS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ENGINEERING; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MONOADENOSINE DIPHOSPHATE RIBOSYLATION; NUCLEAR PORE COMPLEX; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN TARGETING; PROTEOMICS; TANDEM MASS SPECTROMETRY; AMINO ACID SEQUENCE; ANALOGS AND DERIVATIVES; CHEMISTRY; HEK293 CELL LINE; HELA CELL LINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM;

ADP RIBOSE TRANSFERASES; AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HEK293 CELLS; HELA CELLS; HUMANS; NAD; PROTEIN-SERINE-THREONINE KINASES; TANDEM MASS SPECTROMETRY;

EID: 84953223672     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.12.045     Document Type: Article

References (27)

1. Ame J.C., Spenlehauer C., de Murcia G. The PARP superfamily. Bioessays 2004, 26:882-893.
2. Carter-O'Connell I., Cohen M.S. Identifying direct protein targets of poly-ADP-ribose polymerases (PARPs) Using engineered PARP variants-orthogonal nicotinamide adenine dinucleotide (NAD+) analog pairs. Curr. Protoc. Chem. Biol. 2015, 7:121-139.
3. Carter-O'Connell I., Jin H., Morgan R.K., David L.L., Cohen M.S. Engineering the substrate specificity of ADP-ribosyltransferases for identifying direct protein targets. J. Am. Chem. Soc. 2014, 136:5201-5204.
4. Cosi C., Marien M. Implication of poly (ADP-ribose) polymerase (PARP) in neurodegeneration and brain energy metabolism. Decreases in mouse brain NAD+ and ATP caused by MPTP are prevented by the PARP inhibitor benzamide. Ann. N Y Acad. Sci. 1999, 890:227-239.
5. Daniels C.M., Ong S.E., Leung A.K. Phosphoproteomic approach to characterize protein mono- and poly(ADP-ribosyl)ation sites from cells. J. Proteome Res. 2014, 13:3510-3522.
6. Feijs K.L., Kleine H., Braczynski A., Forst A.H., Herzog N., Verheugd P., Linzen U., Kremmer E., Lüscher B. ARTD10 substrate identification on protein microarrays: regulation of GSK3β by mono-ADP-ribosylation. Cell Commun. Signal. 2013, 11:5.
7. Griffis E.R., Altan N., Lippincott-Schwartz J., Powers M.A. Nup98 is a mobile nucleoporin with transcription-dependent dynamics. Mol. Biol. Cell 2002, 13:1282-1297.
8. Griffis E.R., Xu S., Powers M.A. Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes. Mol. Biol. Cell 2003, 14:600-610.
9. Haikarainen T., Venkannagari H., Narwal M., Obaji E., Lee H.W., Nkizinkiko Y., Lehtiö L. Structural basis and selectivity of tankyrase inhibition by a Wnt signaling inhibitor WIKI4. PLoS ONE 2013, 8:e65404.
10. Hottiger M.O., Hassa P.O., Lüscher B., Schüler H., Koch-Nolte F. Toward a unified nomenclature for mammalian ADP-ribosyltransferases. Trends Biochem. Sci. 2010, 35:208-219.
11. Hu B., Wu Z., Hergert P., Henke C.A., Bitterman P.B., Phan S.H. Regulation of myofibroblast differentiation by poly(ADP-ribose) polymerase 1. Am. J. Pathol. 2013, 182:71-83.
12. Jiang H., Kim J.H., Frizzell K.M., Kraus W.L., Lin H. Clickable NAD analogues for labeling substrate proteins of poly(ADP-ribose) polymerases. J. Am. Chem. Soc. 2010, 132:9363-9372.
13. Jungmichel S., Rosenthal F., Altmeyer M., Lukas J., Hottiger M.O., Nielsen M.L. Proteome-wide identification of poly(ADP-Ribosyl)ation targets in different genotoxic stress responses. Mol. Cell 2013, 52:272-285.
14. Kang Y., Cullen B.R. The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences. Genes Dev. 1999, 13:1126-1139.
15. Kleine H., Herrmann A., Lamark T., Forst A.H., Verheugd P., Lüscher-Firzlaff J., Lippok B., Feijs K.L., Herzog N., Kremmer E., et al. Dynamic subcellular localization of the mono-ADP-ribosyltransferase ARTD10 and interaction with the ubiquitin receptor p62. Cell Commun. Signal. 2012, 10:28.
16. Leung A.K., Vyas S., Rood J.E., Bhutkar A., Sharp P.A., Chang P. Poly(ADP-ribose) regulates stress responses and microRNA activity in the cytoplasm. Mol. Cell 2011, 42:489-499.
17. Masutani M., Fujimori H. Poly(ADP-ribosyl)ation in carcinogenesis. Mol. Aspects Med. 2013, 34:1202-1216.
18. Meyer-Ficca M.L., Ihara M., Bader J.J., Leu N.A., Beneke S., Meyer R.G. Spermatid head elongation with normal nuclear shaping requires ADP-ribosyltransferase PARP11 (ARTD11) in mice. Biol. Reprod. 2015, 92:80.
19. Morgan R.K., Cohen M.S. A Clickable Aminooxy Probe for Monitoring Cellular ADP-Ribosylation. ACS Chem. Biol. 2015, 10:1778-1784.
20. Natalizio B.J., Wente S.R. Postage for the messenger: designating routes for nuclear mRNA export. Trends Cell Biol. 2013, 23:365-373.
21. Ruf A., de Murcia G., Schulz G.E. Inhibitor and NAD+ binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling. Biochemistry 1998, 37:3893-3900.
22. Schreiber V., Dantzer F., Ame J.C., de Murcia G. Poly(ADP-ribose): novel functions for an old molecule. Nat. Rev. Mol. Cell Biol. 2006, 7:517-528.
23. Strosznajder R.P., Jesko H., Zambrzycka A. Poly(ADP-ribose) polymerase: the nuclear target in signal transduction and its role in brain ischemia-reperfusion injury. Mol. Neurobiol. 2005, 31:149-167.
24. Verheugd P., Forst A.H., Milke L., Herzog N., Feijs K.L., Kremmer E., Kleine H., Lüscher B. Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10. Nat. Commun. 2013, 4:1683.
25. Vyas S., Matic I., Uchima L., Rood J., Zaja R., Hay R.T., Ahel I., Chang P. Family-wide analysis of poly(ADP-ribose) polymerase activity. Nat. Commun. 2014, 5:4426.
26. Zhang T., Berrocal J.G., Yao J., DuMond M.E., Krishnakumar R., Ruhl D.D., Ryu K.W., Gamble M.J., Kraus W.L. Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase. J. Biol. Chem. 2012, 287:12405-12416.
27. Zhang Y., Wang J., Ding M., Yu Y. Site-specific characterization of the Asp- and Glu-ADP-ribosylated proteome. Nat. Methods 2013, 10:981-984.