메뉴 건너뛰기




Volumn 6, Issue 1, 2016, Pages

Fusidic acid: A bacterial elongation factor inhibitor for the oral treatment of acute and chronic staphylococcal infections

Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION FACTOR; FUSIDIC ACID; RIFAMPICIN; ANTIINFECTIVE AGENT; ELONGATION FACTOR G; PROTEIN SYNTHESIS INHIBITOR;

EID: 84953213447     PISSN: None     EISSN: 21571422     Source Type: Journal    
DOI: 10.1101/cshperspect.a025437     Document Type: Article
Times cited : (102)

References (74)
  • 1
    • 34248365254 scopus 로고    scopus 로고
    • Treatment of staphylococcal prosthetic joint infectionswith debridement, prosthesis retention and oral rifampicin and fusidic acid
    • Aboltins CA, Page MA, Buising KL, Jenney AW, Daffy JR, Choong PF, Stanley PA. 2007. Treatment of staphylococcal prosthetic joint infectionswith debridement, prosthesis retention and oral rifampicin and fusidic acid. Clin Microbiol Infect 13: 586-591.
    • (2007) Clin Microbiol Infect , vol.13 , pp. 586-591
    • Aboltins, C.A.1    Page, M.A.2    Buising, K.L.3    Jenney, A.W.4    Daffy, J.R.5    Choong, P.F.6    Stanley, P.A.7
  • 2
    • 0032568584 scopus 로고    scopus 로고
    • Visualization of elongation factorGon the Escherichia coli 70S ribosome: The mechanism of translocation
    • Agrawal RK, Penczek P, Grassucci RA, Frank J. 1998. Visualization of elongation factorGon the Escherichia coli 70S ribosome: The mechanism of translocation. Proc Natl Acad Sci 95: 6134-6138.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 6134-6138
    • Agrawal, R.K.1    Penczek, P.2    Grassucci, R.A.3    Frank, J.4
  • 3
    • 0037243625 scopus 로고    scopus 로고
    • Molecular analysis of fusidic acid resistance in Staphylococcus aureus
    • Besier S, Ludwig A, Brade V, Wichelhaus TA. 2003. Molecular analysis of fusidic acid resistance in Staphylococcus aureus. Mol Microbiol 47: 463-469.
    • (2003) Mol Microbiol , vol.47 , pp. 463-469
    • Besier, S.1    Ludwig, A.2    Brade, V.3    Wichelhaus, T.A.4
  • 4
    • 16244419018 scopus 로고    scopus 로고
    • Compensatory adaptation to the loss of biological fitness associated with acquisition of fusidic acid resistance in Staphylococcus aureus
    • Besier S, Ludwig A, Brade V, Wichelhaus TA. 2005. Compensatory adaptation to the loss of biological fitness associated with acquisition of fusidic acid resistance in Staphylococcus aureus. Antimicrob Agents Chemother 49: 1426-1431.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 1426-1431
    • Besier, S.1    Ludwig, A.2    Brade, V.3    Wichelhaus, T.A.4
  • 5
    • 84953251773 scopus 로고
    • Chemical classification of antibiotics
    • (ed. Nauta WTh, Rekker RF), Elsevier, Amsterdam
    • Betina V. 1983. Chemical classification of antibiotics. In The chemistry and biology of antibiotics (ed. Nauta WTh, Rekker RF), pp. 154-156. Elsevier, Amsterdam.
    • (1983) The chemistry and biology of antibiotics , pp. 154-156
    • Betina, V.1
  • 6
    • 77349102026 scopus 로고    scopus 로고
    • Spectrum of activity, mutation rates, synergistic interactions, and the effects of pHand serum proteins for fusidic acid (CEM-102)
    • Biedenbach DJ, Rhomberg PR,Mendes RE, Jones RN. 2010. Spectrum of activity, mutation rates, synergistic interactions, and the effects of pHand serum proteins for fusidic acid (CEM-102). DiagnMicrobiol Infect Dis 66: 301-307.
    • (2010) DiagnMicrobiol Infect Dis , vol.66 , pp. 301-307
    • Biedenbach, D.J.1    Rhomberg, P.R.2    Mendes, R.E.3    Jones, R.N.4
  • 7
    • 84922373723 scopus 로고    scopus 로고
    • Fusidic acid targets elongation factor G in several stages of translocation on the bacterial ribosome
    • Borg A, Holm M, Shiroyama I, Hauryliuk V, Pavlov M, Sanyal S, Ehrenberg M. 2015. Fusidic acid targets elongation factor G in several stages of translocation on the bacterial ribosome. J Biol Chem 290: 3440-3454.
    • (2015) J Biol Chem , vol.290 , pp. 3440-3454
    • Borg, A.1    Holm, M.2    Shiroyama, I.3    Hauryliuk, V.4    Pavlov, M.5    Sanyal, S.6    Ehrenberg, M.7
  • 8
    • 77954186721 scopus 로고    scopus 로고
    • Occurrence and molecular characterization of fusidic acid resistance mechanisms among Staphylococcus spp. from European countries (2008)
    • Castanheira M, Watters AA, Mendes RE, Farrell DJ, Jones RN. 2010. Occurrence and molecular characterization of fusidic acid resistance mechanisms among Staphylococcus spp. from European countries (2008). J Antimicrob Chemother 65: 1353-1358.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 1353-1358
    • Castanheira, M.1    Watters, A.A.2    Mendes, R.E.3    Farrell, D.J.4    Jones, R.N.5
  • 10
    • 77956316251 scopus 로고    scopus 로고
    • Staphylococcus aureus elongation factor G-structure and analysis of a target for fusidic acid
    • Chen Y, Koripella RK, Sanyal S, Selmer M. 2010b. Staphylococcus aureus elongation factor G-structure and analysis of a target for fusidic acid. FEBS J 277: 3789-3803.
    • (2010) FEBS J , vol.277 , pp. 3789-3803
    • Chen, Y.1    Koripella, R.K.2    Sanyal, S.3    Selmer, M.4
  • 11
    • 80052437432 scopus 로고    scopus 로고
    • Comparison of articulating and static spacers regarding infection with resistant organisms in total knee arthroplasty
    • Chiang ER, Su YP, Chen TH, Chiu FY, Chen WM. 2011. Comparison of articulating and static spacers regarding infection with resistant organisms in total knee arthroplasty. Acta Orthop 82: 460-464.
    • (2011) Acta Orthop , vol.82 , pp. 460-464
    • Chiang, E.R.1    Su, Y.P.2    Chen, T.H.3    Chiu, F.Y.4    Chen, W.M.5
  • 12
    • 0025696008 scopus 로고
    • Purification and characterization of elongation factor G from bovine liver mitochondria
    • Chung HK, Spremulli LL. 1990. Purification and characterization of elongation factor G from bovine liver mitochondria. J Biol Chem 265: 21000-21004.
    • (1990) J Biol Chem , vol.265 , pp. 21000-21004
    • Chung, H.K.1    Spremulli, L.L.2
  • 15
    • 79955780193 scopus 로고    scopus 로고
    • A randomized, double-blind phase 2 study comparing the efficacy and safety of an oral fusidic acid loading-dose regimen to oral linezolid for the treatment of acute bacterial skin and skin structure infections
    • Craft JC,Moriarty SR, Clark K, ScottD, Degenhardt TP, Still JG, Corey GR, Das A, Fernandes P. 2011. A randomized, double-blind phase 2 study comparing the efficacy and safety of an oral fusidic acid loading-dose regimen to oral linezolid for the treatment of acute bacterial skin and skin structure infections. Clin Infect Dis 52: S520-S526.
    • (2011) Clin Infect Dis , vol.52 , pp. S520-S526
    • Craft, J.C.1    Moriarty, S.R.2    Clark, K.3    Scott, D.4    Degenhardt, T.P.5    Still, J.G.6    Corey, G.R.7    Das, A.8    Fernandes, P.9
  • 17
    • 1642580624 scopus 로고    scopus 로고
    • Fusidic acid resistance in Staphylococcus aureus
    • Dobie D, Gray J. 2004. Fusidic acid resistance in Staphylococcus aureus. Arch Dis Child 89: 74-77.
    • (2004) Arch Dis Child , vol.89 , pp. 74-77
    • Dobie, D.1    Gray, J.2
  • 18
    • 0031052940 scopus 로고    scopus 로고
    • Oral treatment of Staphylococcus spp. infected orthopaedic implants with fusidic acid or ofloxacin in combination with rifampicin
    • Drancourt M, Argenson J, Roiron R, Groulier R, Raoult D. 1997. Oral treatment of Staphylococcus spp. infected orthopaedic implants with fusidic acid or ofloxacin in combination with rifampicin. J Antimicrob Chemother 39: 235-240.
    • (1997) J Antimicrob Chemother , vol.39 , pp. 235-240
    • Drancourt, M.1    Argenson, J.2    Roiron, R.3    Groulier, R.4    Raoult, D.5
  • 19
    • 79955750642 scopus 로고    scopus 로고
    • Efforts to support the development of fusidic acid in the United States
    • Fernandes P, Pereira D. 2011. Efforts to support the development of fusidic acid in the United States. Clin Infect Dis 52: S542-S546.
    • (2011) Clin Infect Dis , vol.52 , pp. S542-S546
    • Fernandes, P.1    Pereira, D.2
  • 21
    • 0034691576 scopus 로고    scopus 로고
    • A ratchet-like inter-subunit reorganization of the ribosome during translocation
    • Frank J, Agrawal RK. 2000. A ratchet-like inter-subunit reorganization of the ribosome during translocation. Nature 406: 318-322.
    • (2000) Nature , vol.406 , pp. 318-322
    • Frank, J.1    Agrawal, R.K.2
  • 22
    • 70350602056 scopus 로고    scopus 로고
    • The structure of the ribosome with elongation factor G trapped in the posttranslocational state
    • Gao YG, Selmer M, Dunham CM, Weixlbaumer A, Kelley AC, Ramakrishnan V. 2009. The structure of the ribosome with elongation factor G trapped in the posttranslocational state. Science 326: 694-699.
    • (2009) Science , vol.326 , pp. 694-699
    • Gao, Y.G.1    Selmer, M.2    Dunham, C.M.3    Weixlbaumer, A.4    Kelley, A.C.5    Ramakrishnan, V.6
  • 23
    • 0013977604 scopus 로고
    • On the metabolism of fusidic acid in man
    • Godtfredsen WO, Vangedal S. 1966. On the metabolism of fusidic acid in man. Acta Chem Scand 20: 1599-1607.
    • (1966) Acta Chem Scand , vol.20 , pp. 1599-1607
    • Godtfredsen, W.O.1    Vangedal, S.2
  • 24
    • 0000882601 scopus 로고
    • Fucidin: A new orally active antibiotic
    • Godtfredsen W, Roholt K, Tybring L. 1962. Fucidin: A new orally active antibiotic. Lancet 1: 928-931.
    • (1962) Lancet , vol.1 , pp. 928-931
    • Godtfredsen, W.1    Roholt, K.2    Tybring, L.3
  • 25
    • 84864252394 scopus 로고    scopus 로고
    • Structure and function of FusB: An elongation factor G-binding fusidic acid resistance protein active in ribosomal translocation and recycling
    • Guo X, Peisker K, Backbro K, Chen Y, Koripella RK, Mandava CS, Sanyal S, Selmer M. 2012. Structure and function of FusB: An elongation factor G-binding fusidic acid resistance protein active in ribosomal translocation and recycling. Open Biol 2: 120016.
    • (2012) Open Biol , vol.2
    • Guo, X.1    Peisker, K.2    Backbro, K.3    Chen, Y.4    Koripella, R.K.5    Mandava, C.S.6    Sanyal, S.7    Selmer, M.8
  • 26
    • 17444373920 scopus 로고    scopus 로고
    • Structural insights into fusidic acid resistance and sensitivity in EF-G
    • HanssonS, Singh R, Gudkov AT, Liljas A, Logan DT. 2005. Structural insights into fusidic acid resistance and sensitivity in EF-G. J Mol Biol 348: 939-949.
    • (2005) J Mol Biol , vol.348 , pp. 939-949
    • Hansson, S.1    Singh, R.2    Gudkov, A.T.3    Liljas, A.4    Logan, D.T.5
  • 28
    • 31044445023 scopus 로고    scopus 로고
    • Dumb and dumber- The potential waste of a useful antistaphylococcal agent: Emerging fusidic acid resistance in Staphylococcus aureus
    • Howden BP, Grayson ML. 2006. Dumb and dumber- The potential waste of a useful antistaphylococcal agent: Emerging fusidic acid resistance in Staphylococcus aureus. Clin Infect Dis 42: 394-400.
    • (2006) Clin Infect Dis , vol.42 , pp. 394-400
    • Howden, B.P.1    Grayson, M.L.2
  • 29
    • 0028214276 scopus 로고
    • Fusidic acid-resistant mutants define three regions in elongation factor G of Salmonella typhimurium
    • JohansonU,HughesD. 1994. Fusidic acid-resistant mutants define three regions in elongation factor G of Salmonella typhimurium. Gene 143: 55-59.
    • (1994) Gene , vol.143 , pp. 55-59
    • Johanson, U.1    HughesD2
  • 30
    • 0030003646 scopus 로고    scopus 로고
    • The dynamic structure of EF-G studied by fusidic acid resistance and internal revertants
    • Johanson U, Aevarsson A, Liljas A, Hughes D. 1996. The dynamic structure of EF-G studied by fusidic acid resistance and internal revertants. J Mol Biol 258: 420-432.
    • (1996) J Mol Biol , vol.258 , pp. 420-432
    • Johanson, U.1    Aevarsson, A.2    Liljas, A.3    Hughes, D.4
  • 31
    • 29144480960 scopus 로고    scopus 로고
    • Contemporary antimicrobial activity of triple antibiotic ointment: A multiphased study of recent clinical isolates in the United States and Australia
    • Jones RN, Li Q, Kohut B, Biedenbach DJ, Bell J, Turnidge JD. 2006. Contemporary antimicrobial activity of triple antibiotic ointment: A multiphased study of recent clinical isolates in the United States and Australia. Diagn Microbiol Infect Dis 54: 63-71.
    • (2006) Diagn Microbiol Infect Dis , vol.54 , pp. 63-71
    • Jones, R.N.1    Li, Q.2    Kohut, B.3    Biedenbach, D.J.4    Bell, J.5    Turnidge, J.D.6
  • 32
    • 77749255802 scopus 로고    scopus 로고
    • Performance of fusidic acid (CEM-102) susceptibility testing reagents: Broth microdilution, disk diffusion, and Etest methods as applied to Staphylococcus aureus
    • Jones RN, Castanheira M, Rhomberg PR,Woosley LN, Pfaller MA. 2010a. Performance of fusidic acid (CEM-102) susceptibility testing reagents: Broth microdilution, disk diffusion, and Etest methods as applied to Staphylococcus aureus. J Clin Microbiol 48: 972-976.
    • (2010) J Clin Microbiol , vol.48 , pp. 972-976
    • Jones, R.N.1    Castanheira, M.2    Rhomberg, P.R.3    Woosley, L.N.4    Pfaller, M.A.5
  • 34
    • 79955756652 scopus 로고    scopus 로고
    • In vitro antimicrobial findings for fusidic acid tested against contemporary (2008-2009) Gram-positive organisms collected in the United States
    • Jones RN, Mendes RE, Sader HS, Castanheira M. 2011. In vitro antimicrobial findings for fusidic acid tested against contemporary (2008-2009) Gram-positive organisms collected in the United States. Clin Infect Dis 52: S477- S486.
    • (2011) Clin Infect Dis , vol.52 , pp. S477-S486
    • Jones, R.N.1    Mendes, R.E.2    Sader, H.S.3    Castanheira, M.4
  • 35
    • 84865777571 scopus 로고    scopus 로고
    • Mechanism of elongation factor-G-mediated fusidic acid resistance and fitness compensation in Staphylococcus aureus
    • Koripella RK, Chen Y, Peisker K, Koh CS, Selmer M, Sanyal S. 2012.Mechanism of elongation factor-G-mediated fusidic acid resistance and fitness compensation in Staphylococcus aureus. J Biol Chem 287: 30257-30267.
    • (2012) J Biol Chem , vol.287 , pp. 30257-30267
    • Koripella, R.K.1    Chen, Y.2    Peisker, K.3    Koh, C.S.4    Selmer, M.5    Sanyal, S.6
  • 37
    • 79955783716 scopus 로고    scopus 로고
    • Activity of fusidic acid against extracellular and intracellular Staphylococcus aureus: Influence of pH and comparison with linezolid and clindamycin
    • Lemaire S, Van Bambeke F, Pierard D, Appelbaum PC, Tulkens PM. 2011. Activity of fusidic acid against extracellular and intracellular Staphylococcus aureus: Influence of pH and comparison with linezolid and clindamycin. Clin Infect Dis 52: S493-S503.
    • (2011) Clin Infect Dis , vol.52 , pp. S493-S503
    • Lemaire, S.1    Van Bambeke, F.2    Pierard, D.3    Appelbaum, P.C.4    Tulkens, P.M.5
  • 38
    • 79955775921 scopus 로고    scopus 로고
    • Fusidic acid
    • (ed. Mandell GL, et al.), Churchill Livingstone, Philadelphia
    • MandellLA. 2010. Fusidic acid. In Principles and practice of infectious diseases (ed. Mandell GL, et al.), pp. 355-357. Churchill Livingstone, Philadelphia.
    • (2010) Principles and practice of infectious diseases , pp. 355-357
    • Mandell, L.A.1
  • 39
    • 33846887420 scopus 로고    scopus 로고
    • Phylogenetic distribution of translational GTPases in bacteria
    • Margus T, Remm M, Tenson T. 2007. Phylogenetic distribution of translational GTPases in bacteria. BMC Genomics 8: 15.
    • (2007) BMC Genomics , vol.8 , pp. 15
    • Margus, T.1    Remm, M.2    Tenson, T.3
  • 40
    • 0035800829 scopus 로고    scopus 로고
    • Mutations in the G-domain of elongation factor G from Thermus thermophilus affect both its interaction with GTP and fusidic acid
    • MartemyanovKA, Liljas A, Yarunin AS, Gudkov AT. 2001. Mutations in the G-domain of elongation factor G from Thermus thermophilus affect both its interaction with GTP and fusidic acid. J Biol Chem 276: 28774-28778.
    • (2001) J Biol Chem , vol.276 , pp. 28774-28778
    • Martemyanov, K.A.1    Liljas, A.2    Yarunin, A.S.3    Gudkov, A.T.4
  • 41
    • 1442360926 scopus 로고    scopus 로고
    • Fusidic acid resistance in community isolates of methicillin susceptible Staphylococcus aureus and the use of topical fusidic acid: A retrospective case-control study
    • Mason BW, Howard AJ. 2004. Fusidic acid resistance in community isolates of methicillin susceptible Staphylococcus aureus and the use of topical fusidic acid: A retrospective case-control study. Int J Antimicrob Agents 23: 300-303.
    • (2004) Int J Antimicrob Agents , vol.23 , pp. 300-303
    • Mason, B.W.1    Howard, A.J.2
  • 42
    • 79952325895 scopus 로고    scopus 로고
    • Distribution of fusidic acid resistance determinants in methicillin-resistant Staphylococcus aureus
    • McLaws FB, Larsen AR, Skov RL, Chopra I, O'Neill AJ. 2011. Distribution of fusidic acid resistance determinants in methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 55: 1173-1176.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 1173-1176
    • McLaws, F.B.1    Larsen, A.R.2    Skov, R.L.3    Chopra, I.4    O'Neill, A.J.5
  • 43
    • 44449165928 scopus 로고    scopus 로고
    • Delayed development of linezolid resistance in Staphylococcus aureus following exposure to low levels of antimicrobial agents
    • Miller K, O'Neill AJ,Wilcox MH, Ingham E, Chopra I. 2008. Delayed development of linezolid resistance in Staphylococcus aureus following exposure to low levels of antimicrobial agents. Antimicrob Agents Chemother 52: 1940- 1944.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 1940-1944
    • Miller, K.1    O'Neill, A.J.2    Wilcox, M.H.3    Ingham, E.4    Chopra, I.5
  • 44
    • 0035029364 scopus 로고    scopus 로고
    • Biological cost and compensatory evolution in fusidic acidresistant Staphylococcus aureus
    • Nagaev I, Bjorkman J, Andersson DI, Hughes D. 2001. Biological cost and compensatory evolution in fusidic acidresistant Staphylococcus aureus. Mol Microbiol 40: 433- 439.
    • (2001) Mol Microbiol , vol.40 , pp. 433-439
    • Nagaev, I.1    Bjorkman, J.2    Andersson, D.I.3    Hughes, D.4
  • 45
    • 36749058900 scopus 로고    scopus 로고
    • Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus
    • Norstrom T, Lannergard J, Hughes D. 2007. Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. Antimicrob Agents Chemother 51: 4438-4446.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 4438-4446
    • Norstrom, T.1    Lannergard, J.2    Hughes, D.3
  • 46
    • 79955064411 scopus 로고    scopus 로고
    • Evaluation of the pharmacokinetics-pharmacodynamics of fusidic acid against Staphylococcus aureus and Streptococcus pyogenes using in vitro infection models: Implications for dose selection
    • Okusanya OO, Tsuji BT, Bulitta JB, Forrest A, Bulik CC, Bhavnani SM, Fernandes P, Ambrose PG. 2011. Evaluation of the pharmacokinetics-pharmacodynamics of fusidic acid against Staphylococcus aureus and Streptococcus pyogenes using in vitro infection models: Implications for dose selection. Diagn Microbiol Infect Dis 70: 101-111.
    • (2011) Diagn Microbiol Infect Dis , vol.70 , pp. 101-111
    • Okusanya, O.O.1    Tsuji, B.T.2    Bulitta, J.B.3    Forrest, A.4    Bulik, C.C.5    Bhavnani, S.M.6    Fernandes, P.7    Ambrose, P.G.8
  • 47
    • 84953282389 scopus 로고    scopus 로고
    • Rifampin (RIF) significantly reduces plasma concentrations of fusidic acid (FA) when used in combination for treatment of prosthetic joint infection (PJI)
    • Poster 2352. Copenhagen, Denmark
    • Oldach D, Stolarski E, Murphy B, Mould D, Das A, Fernandes P. 2015. Rifampin (RIF) significantly reduces plasma concentrations of fusidic acid (FA) when used in combination for treatment of prosthetic joint infection (PJI). In 25th European Congress of Clinical Microbiology and Infectious Diseases, Poster 2352. Copenhagen, Denmark.
    • (2015) 25th European Congress of Clinical Microbiology and Infectious Diseases
    • Oldach, D.1    Stolarski, E.2    Murphy, B.3    Mould, D.4    Das, A.5    Fernandes, P.6
  • 49
    • 33645079390 scopus 로고    scopus 로고
    • Molecular basis of fusB-mediated resistance to fusidic acid in Staphylococcus aureus
    • O'Neill AJ, Chopra I. 2006. Molecular basis of fusB-mediated resistance to fusidic acid in Staphylococcus aureus. Mol Microbiol 59: 664-676.
    • (2006) Mol Microbiol , vol.59 , pp. 664-676
    • O'Neill, A.J.1    Chopra, I.2
  • 50
    • 0035025018 scopus 로고    scopus 로고
    • Mutation frequencies for resistance to fusidic acid and rifampicin in Staphylococcus aureus
    • O'Neill AJ, Cove JH, Chopra I. 2001. Mutation frequencies for resistance to fusidic acid and rifampicin in Staphylococcus aureus. J Antimicrob Chemother 47: 647-650.
    • (2001) J Antimicrob Chemother , vol.47 , pp. 647-650
    • O'Neill, A.J.1    Cove, J.H.2    Chopra, I.3
  • 51
    • 34248592109 scopus 로고    scopus 로고
    • Characterization of the epidemic European fusidic acid-resistant impetigo clone of Staphylococcus aureus
    • O'Neill AJ, Larsen AR, Skov R, Henriksen AS, Chopra I. 2007. Characterization of the epidemic European fusidic acid-resistant impetigo clone of Staphylococcus aureus. J Clin Microbiol 45: 1505-1510.
    • (2007) J Clin Microbiol , vol.45 , pp. 1505-1510
    • O'Neill, A.J.1    Larsen, A.R.2    Skov, R.3    Henriksen, A.S.4    Chopra, I.5
  • 52
    • 73549115374 scopus 로고    scopus 로고
    • Evaluation of the activity of fusidic acid tested against contemporary Gram-positive clinical isolates from the USA and Canada
    • Pfaller MA, Castanheira M, Sader HS, Jones RN. 2010. Evaluation of the activity of fusidic acid tested against contemporary Gram-positive clinical isolates from the USA and Canada. Int J Antimicrob Agents 35: 282-287.
    • (2010) Int J Antimicrob Agents , vol.35 , pp. 282-287
    • Pfaller, M.A.1    Castanheira, M.2    Sader, H.S.3    Jones, R.N.4
  • 53
    • 84953328806 scopus 로고    scopus 로고
    • Successful treatment of multi-drug resistant Acinetobacter baumannii ventilatorassociated pneumonia with a novel colistin and fusidic acid combination therapy
    • Poster 481. Philadelphia, PA
    • Phee L, BB, Wareham DW. 2014. Successful treatment of multi-drug resistant Acinetobacter baumannii ventilatorassociated pneumonia with a novel colistin and fusidic acid combination therapy. In ID Week, Poster 481. Philadelphia, PA.
    • (2014) ID Week
    • Phee, L.1    Wareham, D.W.2
  • 54
    • 84939863727 scopus 로고    scopus 로고
    • Colistin and fusidic acid: A novel potent synergistic combination for the treatment of multi-drug resistant Acinetobacter baumannii infections
    • Phee LM, Betts JW, Bharathan B, Wareham DW. 2015. Colistin and fusidic acid: A novel potent synergistic combination for the treatment of multi-drug resistant Acinetobacter baumannii infections. Antimicrob Agents Chemother 59: 4544-4550.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 4544-4550
    • Phee, L.M.1    Betts, J.W.2    Bharathan, B.3    Wareham, D.W.4
  • 55
    • 0023231554 scopus 로고
    • The pharmacokinetics of fusidic acid
    • Reeves DS. 1987. The pharmacokinetics of fusidic acid. J Antimicrob Chemother 20: 467-476.
    • (1987) J Antimicrob Chemother , vol.20 , pp. 467-476
    • Reeves, D.S.1
  • 56
    • 84882338030 scopus 로고    scopus 로고
    • In vitro activity of CEM-102 (fusidic acid) against prevalent clones and resistant phenotypes of Staphylococcus aureus
    • Sahm DF, Deane J, Pillar CM, Fernandes P. 2013. In vitro activity of CEM-102 (fusidic acid) against prevalent clones and resistant phenotypes of Staphylococcus aureus. Antimicrob Agents Chemother 57: 4535-4536.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 4535-4536
    • Sahm, D.F.1    Deane, J.2    Pillar, C.M.3    Fernandes, P.4
  • 57
    • 65249164177 scopus 로고    scopus 로고
    • Distinct functions of elongation factor G in ribosome recycling and translocation
    • Savelsbergh A, RodninaMV,WintermeyerW. 2009. Distinct functions of elongation factor G in ribosome recycling and translocation. RNA 15: 772-780.
    • (2009) RNA , vol.15 , pp. 772-780
    • Savelsbergh, A.1    Rodnina, M.V.2    WintermeyerW3
  • 58
    • 84953308676 scopus 로고    scopus 로고
    • Activity of fusidic acid (FUS) alone or in combination with daptomycin (DAP), vancomycin (VAN), or linezolid (LZD) in an in vitro model of Staphylococcus aureus biofilm
    • Abstr. EV0056. Copenhagen, Denmark
    • Siala W, R-V H, Fernandes P, Tulkens PM, Van Bambeke F. 2015. Activity of fusidic acid (FUS) alone or in combination with daptomycin (DAP), vancomycin (VAN), or linezolid (LZD) in an in vitro model of Staphylococcus aureus biofilm. In the 25th European Congress on Clinical Microbiology and Infectious Diseases, Abstr. EV0056. Copenhagen, Denmark.
    • (2015) The 25th European Congress on Clinical Microbiology and Infectious Diseases
    • Siala, W.1    R-V, H.2    Fernandes, P.3    Tulkens, P.M.4    Van Bambeke, F.5
  • 59
    • 0032838434 scopus 로고    scopus 로고
    • Fusidic acid in skin and soft tissue infections
    • Spelman D. 1999. Fusidic acid in skin and soft tissue infections. Int J Antimicrob Agents 12: S59-S66.
    • (1999) Int J Antimicrob Agents , vol.12 , pp. S59-S66
    • Spelman, D.1
  • 60
    • 79955752771 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of single, multiple, and loading doses of fusidic acid in healthy subjects
    • StillJG, Clark K, Degenhardt TP, Scott D, Fernandes P, Gutierrez MJ. 2011. Pharmacokinetics and safety of single, multiple, and loading doses of fusidic acid in healthy subjects. Clin Infect Dis 52: S504-S512.
    • (2011) Clin Infect Dis , vol.52 , pp. S504-S512
    • Still, J.G.1    Clark, K.2    Degenhardt, T.P.3    Scott, D.4    Fernandes, P.5    Gutierrez, M.J.6
  • 62
    • 33745605783 scopus 로고    scopus 로고
    • Infections associated with orthopedic implants
    • Trampuz A, Widmer AF. 2006. Infections associated with orthopedic implants. Curr Opin Infect Dis 19: 349-356.
    • (2006) Curr Opin Infect Dis , vol.19 , pp. 349-356
    • Trampuz, A.1    Widmer, A.F.2
  • 63
    • 11244285327 scopus 로고    scopus 로고
    • Interaction of the plasmid-encoded quinolone resistance protein Qnr with Escherichia coli DNA gyrase
    • Tran JH, Jacoby GA, Hooper DC. 2005. Interaction of the plasmid-encoded quinolone resistance protein Qnr with Escherichia coli DNA gyrase. Antimicrob Agents Chemother 49: 118-125.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 118-125
    • Tran, J.H.1    Jacoby, G.A.2    Hooper, D.C.3
  • 64
    • 79955768964 scopus 로고    scopus 로고
    • Application of pharmacokinetic- pharmacodynamic modeling and the justification of a novel fusidic acid dosing regimen: Raising Lazarus from the dead
    • Tsuji BT, Okusanya OO, Bulitta JB, Forrest A, Bhavnani SM, Fernandez PB, Ambrose PG. 2011. Application of pharmacokinetic- pharmacodynamic modeling and the justification of a novel fusidic acid dosing regimen: Raising Lazarus from the dead. Clin Infect Dis 52: S513-S519.
    • (2011) Clin Infect Dis , vol.52 , pp. S513-S519
    • Tsuji, B.T.1    Okusanya, O.O.2    Bulitta, J.B.3    Forrest, A.4    Bhavnani, S.M.5    Fernandez, P.B.6    Ambrose, P.G.7
  • 65
    • 0032856048 scopus 로고    scopus 로고
    • Fusidic acid pharmacology, pharmacokinetics and pharmacodynamics
    • TurnidgeJ. 1999. Fusidic acid pharmacology, pharmacokinetics and pharmacodynamics. Int J Antimicrob Agents 12: S23-S34.
    • (1999) Int J Antimicrob Agents , vol.12 , pp. S23-S34
    • Turnidge, J.1
  • 66
    • 0026773863 scopus 로고
    • Levels of fusidic acid in skin blister fluid and serum after repeated administration of two dosages (250 and 500 mg)
    • VaillantL, Machet L, Taburet AM, Sorensen H, Lorette G. 1992. Levels of fusidic acid in skin blister fluid and serum after repeated administration of two dosages (250 and 500 mg). Br J Dermatol 126: 591-595.
    • (1992) Br J Dermatol , vol.126 , pp. 591-595
    • Vaillant, L.1    Machet, L.2    Taburet, A.M.3    Sorensen, H.4    Lorette, G.5
  • 68
    • 0025240889 scopus 로고
    • The antimicrobial activity of fusidic acid
    • Verbist L. 1990. The antimicrobial activity of fusidic acid. J Antimicrob Chemother 25: 1-5.
    • (1990) J Antimicrob Chemother , vol.25 , pp. 1-5
    • Verbist, L.1
  • 71
    • 84890445788 scopus 로고    scopus 로고
    • Ribosome-targeting antibiotics and mechanisms of bacterial resistance
    • Wilson DN. 2014. Ribosome-targeting antibiotics and mechanisms of bacterial resistance. Nat Rev Microbiol 12: 35-48.
    • (2014) Nat Rev Microbiol , vol.12 , pp. 35-48
    • Wilson, D.N.1
  • 72
    • 79955765671 scopus 로고    scopus 로고
    • Case report: Treatment of chronic osteomyelitis
    • Wolfe CR. 2011. Case report: Treatment of chronic osteomyelitis. ClinInfect Dis 52: S538-S541.
    • (2011) ClinInfect Dis , vol.52 , pp. S538-S541
    • Wolfe, C.R.1
  • 73
    • 3543083961 scopus 로고    scopus 로고
    • A double-blind randomized controlled trial of fusidic acid and metronidazole for treatment of an initial episode of Clostridium difficileassociated diarrhea
    • WulltM, Odenholt I. 2004. A double-blind randomized controlled trial of fusidic acid and metronidazole for treatment of an initial episode of Clostridium difficileassociated diarrhea. J Antimicrob Chemother 54: 211-216.
    • (2004) J Antimicrob Chemother , vol.54 , pp. 211-216
    • Wullt, M.1    Odenholt, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.