Molecular basis of mRNA cap recognition by influenza B polymerase PB2 subunit

Journal of Biological Chemistry

Volumn 291, Issue 1, 2016, Pages 363-370

  Xie, Lili ^a   Wartchow, Charles ^a   Shia, Steven ^a   Uehara, Kyoko ^a   Steffek, Micah ^a   Warne, Robert ^a   Sutton, James ^a   Muiru, Gladys T ^a   Leonard, Vincent H J ^a   Bussiere, Dirksen E ^a   Ma, Xiaolei ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINS; RNA; VIRUSES;

BIOPHYSICAL STUDIES; CAP STRUCTURE; CAP-BINDING; DRUG DESIGN; DUAL INHIBITORS; INFLUENZA A; INFLUENZA VIRUS; MOLECULAR BASIS;

NUCLEIC ACIDS;

GUANINE; GUANOSINE TRIPHOSPHATE; MESSENGER RNA; PROTEIN PB2; RIBOSE; RNA POLYMERASE; UNCLASSIFIED DRUG; 7-METHYLGUANOSINE TRIPHOSPHATE; CAPPED RNA; PB2 PROTEIN, INFLUENZA VIRUS; PROTEIN SUBUNIT; SOLUTION AND SOLUBILITY; VIRAL PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; BIOPHYSICS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIFFERENTIAL SCANNING FLUOROMETRY; FLUOROMETRY; HYDROGEN BOND; INFLUENZA A VIRUS; INFLUENZA B VIRUS; ISOTHERMAL TITRATION CALORIMETRY; LIGAND BINDING; MOLECULAR INTERACTION; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RNA CAPPING; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY; CALORIMETRY; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; PLIABILITY; PROTEIN SUBUNIT; SOLUTION AND SOLUBILITY;

CALORIMETRY; CRYSTALLOGRAPHY, X-RAY; FLUOROMETRY; INFLUENZA A VIRUS; INFLUENZA B VIRUS; MODELS, MOLECULAR; PLIABILITY; PROTEIN SUBUNITS; RNA CAP ANALOGS; RNA CAPS; RNA, MESSENGER; SOLUTIONS; VIRAL PROTEINS;

EID: 84952942323     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.693051     Document Type: Article

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