Amphetamine increases activity but not exploration in humans and mice

Psychopharmacology

Volumn 233, Issue 2, 2016, Pages 225-233

  Minassian, Arpi ^a,b   Young, Jared W ^a,c   Cope, Zackary A ^a   Henry, Brook L ^a   Geyer, Mark A ^a,c   Perry, William ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Veteran's Administration   (United States)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

Amphetamine; Bipolar disorder; Catecholamines; Dopamine; Exploration; Mania; Motor activity

Indexed keywords

AMPHETAMINE; ADRENERGIC RECEPTOR AFFECTING AGENT; CATECHOLAMINE; CENTRAL STIMULANT AGENT; DEXAMPHETAMINE; DOPAMINE; DOPAMINE UPTAKE INHIBITOR;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIORAL PATTERN MONITOR; BIPOLAR DISORDER; CATECHOLAMINE RELEASE; CONTROLLED STUDY; DOSE RESPONSE; EXPLORATORY BEHAVIOR; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MANIA; MOTOR ACTIVITY; MOUSE; MOVEMENT (PHYSIOLOGY); MULTIPLE CYCLE TREATMENT; NONHUMAN; NORMAL HUMAN; PATHOPHYSIOLOGY; PATIENT COMPLIANCE; PRIORITY JOURNAL; SINGLE DRUG DOSE; SPATIAL BEHAVIOR; ADOLESCENT; ANIMAL; C57BL MOUSE; CHEMICAL STIMULATION; DRUG EFFECTS; METABOLISM; MOTIVATION; PSYCHOLOGY; RANDOMIZED CONTROLLED TRIAL; YOUNG ADULT;

ADOLESCENT; ADRENERGIC UPTAKE INHIBITORS; ADULT; ANIMALS; BIPOLAR DISORDER; CATECHOLAMINES; CENTRAL NERVOUS SYSTEM STIMULANTS; DEXTROAMPHETAMINE; DOPAMINE; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXPLORATORY BEHAVIOR; FEMALE; GOALS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; STIMULATION, CHEMICAL; YOUNG ADULT;

EID: 84952911046     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-015-4098-4     Document Type: Article

References (51)

1. Anand A, Barkay G, Dzemidzic M, Albrecht D, Karne H, Zheng QH, Hutchins GD, Normandin MD, Yoder KK (2011) Striatal dopamine transporter availability in unmedicated bipolar disorder. Bipolar Disord 13:406-413
2. Ballard ME, Gallo DA, de Wit H (2014) Amphetamine increases errors during episodic memory retrieval. J Clin Psychopharmacol 34:85-92
3. Cheniaux E, Filgueiras A, Silva Rde A, Silveira LA, Nunes AL, Landeira-Fernandez J (2014) Increased energy/activity, not mood changes, is the core feature of mania. J Affect Disord 152-154:256-261
4. Cousins DA, Butts K, Young AH (2009) The role of dopamine in bipolar disorder. Bipolar Disord 11:787-806
5. de Wit H, Enggasser JL, Richards JB (2002) Acute administration of d-amphetamine decreases impulsivity in healthy volunteers. Neuropsychopharmacology 27:813-825
6. DSM-5 (2013) Diagnostic and statistical manual of mental health disorders: DSM-5, 5th edn. American Psychiatric Publishing, Washington, DC
7. Einat H (2006) Modelling facets of mania - new directions related to the notion of endophenotypes. J Psychopharmacol (Oxford, England) 20:714-722
8. Farrow TF, Hunter MD, Haque R, Spence SA (2006) Modafinil and unconstrained motor activity in schizophrenia: double-blind crossover placebo-controlled trial. Br J Psychiatry J Ment Sci 189:461-462
9. Frey BN, Valvassori SS, Reus GZ, Martins MR, Petronilho FC, Bardini K, Dal-Pizzol F, Kapczinski F, Quevedo J (2006) Changes in antioxidant defense enzymes after d-amphetamine exposure: implications as an animal model of mania. Neurochem Res 31:699-703
10. Geyer MA, Russo PV, Masten VL (1986) Multivariate assessment of locomotor behavior: pharmacological and behavioral analyses. Pharmacol Biochem Behav 25:277-288
11. Godfrey A, Conway R, Meagher D, Olaighin G (2008) Direct measurement of human movement by accelerometry. Med Eng Phys 30:1364-1386
12. Greenwald MK, Schuster CR, Johanson CE, Jewell J (1998) Automated measurement of motor activity in human subjects: effects of repeated testing and d-amphetamine. Pharmacol Biochem Behav 59:59-65
13. Greenwood TA, Alexander M, Keck PE, McElroy S, Sadovnick AD, Remick RA, Kelsoe JR (2001) Evidence for linkage disequilibrium between the dopamine transporter and bipolar disorder. Am J Med Genet 105:145-151
14. Greenwood TA, Schork NJ, Eskin E, Kelsoe JR (2006) Identification of additional variants within the human dopamine transporter gene provides further evidence for an association with bipolar disorder in two independent samples. Mol Psychiatry 11(125-33):115
15. Grossman F, Potter WZ (1999) Catecholamines in depression: a cumulative study of urinary norepinephrine and its major metabolites in unipolar and bipolar depressed patients versus healthy volunteers at the NIMH. Psychiatry Res 87:21-27
16. Han DD, Gu HH (2006) Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs. BMC Pharmacol 6:6
17. Hart AB, Engelhardt BE, Wardle MC, Sokoloff G, Stephens M, de Wit H, Palmer AA (2012) Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13). PLoS One 7:e42646
18. Henry BL, Minassian A, van Rhenen M, Young JW, Geyer MA, Perry W (2011) Effect of methamphetamine dependence on inhibitory deficits in a novel human open-field paradigm. Psychopharmacology 215:697-707
19. Henry BL, Minassian A, Patt VM, Hua J, Young JW, Geyer MA, Perry W (2013) Inhibitory deficits in euthymic bipolar disorder patients assessed in the human behavioral pattern monitor. J Affect Disord 150:948-954
20. Hidalgo (2010) Equivital life monitor. Cambridgeshire
21. Hijzen TH, Broersen LM, Slangen JL (1991) Effects of subchronic d-amphetamine on prepulse and gap inhibition of the acoustic startle reflex in rats. Biol Psychiatry 29:1119-1128
22. IBM Corporation (2013) IBM SPSS Statistics for Windows. IBM Corp, Armonk
23. Koslow SH, Maas JW, Bowden CL, Davis JM, Hanin I, Javaid J (1983) CSF and urinary biogenic amines and metabolites in depression and mania. A controlled, univariate analysis. Arch Gen Psychiatry 40:999-1010
24. Machado-Vieira R, Kapczinski F, Soares JC (2004) Perspectives for the development of animal models of bipolar disorder. Prog Neuro-Psychopharmacol Biol Psychiatry 28:209-224
25. Minassian A, Henry BL, Geyer MA, Paulus MP, Young JW, Perry W (2010) The quantitative assessment of motor activity in mania and schizophrenia. J Affect Disord 120:200-206
26. Minassian A, Henry BL, Young JW, Masten V, Geyer MA, Perry W (2011) Repeated assessment of exploration and novelty seeking in the human behavioral pattern monitor in bipolar disorder patients and healthy individuals. PLoS One 6:e24185
27. Najt P, Perez J, Sanches M, Peluso MA, Glahn D, Soares JC (2007) Impulsivity and bipolar disorder. Eur Neuropsychopharmacol 17:313-320
28. Paulus MP, Geyer MA (1991) A scaling approach to find order parameters quantifying the effects of dopaminergic agents on unconditioned motor activity in rats. Prog Neuro-Psychopharmacol Biol Psychiatry 15:903-919
29. Paulus MP, Minassian A, Masten V, Feifel D, Geyer MA, Perry W (2007) Human behavioral pattern monitor differentiates activity patterns of bipolar manic and attention deficit hyperactivity subjects. Biol Psychiatry 61:227S
30. Perry W, Minassian A, Paulus MP, Young JW, Kincaid MJ, Ferguson EJ, Henry BL, Zhuang X, Masten VL, Sharp RF, Geyer MA (2009) A reverse-translational study of dysfunctional exploration in psychiatric disorders: from mice to men. Arch Gen Psychiatry 66:1072-1080
31. Perry W, Minassian A, Henry B, Kincaid M, Young JW, Geyer MA (2010) Quantifying over-activity in bipolar and schizophrenia patients in a human open field paradigm. Psychiatry Res 178:84-91
32. Pierce K, Courchesne E (2001) Evidence for a cerebellar role in reduced exploration and stereotyped behavior in autism. Biol Psychiatry 49:655-664
33. Post RM, Weiss SR (1989) Sensitization, kindling, and anticonvulsants in mania. J Clin Psychiatry 50(Suppl):23-30, discussion 45-7
34. Ralph RJ, Paulus MP, Fumagalli F, Caron MG, Geyer MA (2001a) Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists. J Neurosci Off J Soc Neurosci 21:305-313
35. Ralph RJ, Paulus MP, Geyer MA (2001b) Strain-specific effects of amphetamine on prepulse inhibition and patterns of locomotor behavior in mice. J Pharmacol Exp Ther 298:148-155
36. Reagan-Shaw S, Nihal M, Ahmad N (2008) Dose translation from animal to human studies revisited. FASEB J 22:659-661
37. Risbrough VB, Masten VL, Caldwell S, Paulus MP, Low MJ, Geyer MA (2006) Differential contributions of dopamine D1, D2, and D3 receptors to MDMA-induced effects on locomotor behavior patterns in mice. Neuropsychopharmacology 31:2349-2358
38. Salvi V, Fagiolini A, Swartz HA, Maina G, Frank E (2008) The use of antidepressants in bipolar disorder. J Clin Psychiatry 69:1307-1318
39. Shaldivin A, Kaptsan A, Belmaker RH, Einat H, Grisaru N (2001) Transcranial magnetic stimulation in an amphetamine hyperactivity model of mania. Bipolar Disord 3:30-34
40. Silverstone PH, Pukhovsky A, Rotzinger S (1998) Lithium does not attenuate the effects of D-amphetamine in healthy volunteers. Psychiatry Res 79:219-226
41. Stevens J (1992) Applied multivariate statistics for the social sciences. Lawrence Erlbaum Associates, Inc., New Jersey
42. Tanaka S, Young JW, Halberstadt AL, Masten VL, Geyer MA (2012) Four factors underlying mouse behavior in an open field. Behav Brain Res 233:55-61
43. van Enkhuizen J, Janowsky DS, Olivier B, Minassian A, Perry W, Young JW, Geyer MA (2015) The catecholaminergic-cholinergic balance hypothesis of bipolar disorder revisited. Eur J Pharmacol 753:114-126
44. Viggiano D, Ruocco LA, Arcieri S, Sadile AG (2004) Involvement of norepinephrine in the control of activity and attentive processes in animal models of attention deficit hyperactivity disorder. Neural Plast 11:133-149
45. Vivometrics (2002) The LifeShirt System™, Ventura
46. Weafer J, de Wit H (2013) Inattention, impulsive action, and subjective response to D-amphetamine. Drug Alcohol Depend 133:127-133
47. Wong YN, Wang L, Hartman L, Simcoe D, Chen Y, Laughton W, Eldon R, Markland C, Grebow P (1998) Comparison of the single-dose pharmacokinetics and tolerability of modafinil and dextroamphetamine administered alone or in combination in healthy male volunteers. J Clin Pharmacol 38:971-978
48. Young JW, Goey AK, Minassian A, Perry W, Paulus MP, Geyer MA (2010a) GBR 12909 administration as a mouse model of bipolar disorder mania: mimicking quantitative assessment of manic behavior. Psychopharmacology 208:443-454
49. Young JW, Goey AK, Minassian A, Perry W, Paulus MP, Geyer MA (2010b) The mania-like exploratory profile in genetic dopamine transporter mouse models is diminished in a familiar environment and reinstated by subthreshold psychostimulant administration. Pharmacol Biochem Behav 96:7-15
50. Young JW, Henry BL, Geyer MA (2011a) Predictive animal models of mania: hits, misses and future directions. Br J Pharmacol 164:1263-1284
51. Young JW, Kooistra K, Geyer MA (2011b) Dopamine receptor mediation of the exploratory/hyperactivity effects of modafinil. Neuropsychopharmacology 36:1385-1396