Spironolactone inhibits the activity of the Na+/H+ exchanger in the aorta of mineralocorticoid-induced hypertensive rats

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 16, Issue 4, 2015, Pages 1225-1231

  Carreño, Juan E ^a   Verdugo, Fernando J ^a   Contreras, Felipe ^a   Montellano, Felipe A ^a   Veloso, Sebastian ^a   Schalper, Kurt A ^b   Sandoval, Mauricio ^a   Villanueva, Sandra ^a   Marusic, Elisa ^a   Irarrazabal, Carlos E ^a  

^a UNIVERSIDAD DE LOS ANDES   (Chile)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Desoxycorticosterone; Mineralocorticoid receptor; Mineralocorticoid receptor antagonists; Sodium hydrogen antiporter; Vasoconstriction

Indexed keywords

5 (N ETHYL N ISOPROPYL)AMILORIDE; DEOXYCORTICOSTERONE; MESSENGER RNA; MINERALOCORTICOID RECEPTOR; PHENYLEPHRINE; SODIUM PROTON EXCHANGE PROTEIN; SPIRONOLACTONE; MINERALOCORTICOID; SLC9A1 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTIC TISSUE; ARTERIAL STIFFNESS; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DRUG MECHANISM; GENE EXPRESSION; HISTOLOGY; HYPERTENSION; MALE; MORPHOMETRICS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE CONTRACTILITY; SPRAGUE DAWLEY RAT; SYSTOLIC BLOOD PRESSURE; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; AORTA; BLOOD PRESSURE; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; PATHOPHYSIOLOGY; STAINING; VASOCONSTRICTION;

ANIMALS; AORTA; BLOOD PRESSURE; DESOXYCORTICOSTERONE; HYPERTENSION; MALE; MINERALOCORTICOIDS; PHENYLEPHRINE; RATS, SPRAGUE-DAWLEY; SODIUM-HYDROGEN ANTIPORTER; SPIRONOLACTONE; STAINING AND LABELING; VASOCONSTRICTION;

EID: 84952879116     PISSN: 14703203     EISSN: 17528976     Source Type: Journal    
DOI: 10.1177/1470320315587193     Document Type: Article

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