메뉴 건너뛰기




Volumn 23, Issue 1, 2016, Pages 111-119

Cyclin D1 gene amplification is highly homogeneous in breast cancer

Author keywords

Breast cancer; Cyclin D1; FISH; Heterogeneity; Heterogeneity TMA

Indexed keywords

CYCLIN D1; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; CCND1 PROTEIN, HUMAN;

EID: 84952876907     PISSN: 13406868     EISSN: 18804233     Source Type: Journal    
DOI: 10.1007/s12282-014-0538-y     Document Type: Article
Times cited : (36)

References (52)
  • 1
    • 11244296162 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen resistance
    • PID: 15613444, COI: 1:CAS:528:DC%2BD2MXhtVarsLk%3D
    • Ring A, Dowsett M. Mechanisms of tamoxifen resistance. Endocr Relat Cancer. 2004;11(4):643–58. doi:10.1677/erc.1.00776.
    • (2004) Endocr Relat Cancer , vol.11 , Issue.4 , pp. 643-658
    • Ring, A.1    Dowsett, M.2
  • 2
    • 57349113761 scopus 로고    scopus 로고
    • Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen
    • PID: 19005469, COI: 1:CAS:528:DC%2BD1cXhsVGlur7E
    • Hurtado A, Holmes KA, Geistlinger TR, Hutcheson IR, Nicholson RI, Brown M, et al. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen. Nature. 2008;456(7222):663–6. doi:10.1038/nature07483.
    • (2008) Nature , vol.456 , Issue.7222 , pp. 663-666
    • Hurtado, A.1    Holmes, K.A.2    Geistlinger, T.R.3    Hutcheson, I.R.4    Nicholson, R.I.5    Brown, M.6
  • 3
    • 33646940460 scopus 로고    scopus 로고
    • Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients
    • PID: 16705121, COI: 1:CAS:528:DC%2BD28XkvVSrs78%3D
    • Holm C, Rayala S, Jirstrom K, Stal O, Kumar R, Landberg G. Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients. J Natl Cancer Inst. 2006;98(10):671–80. doi:10.1093/jnci/djj185.
    • (2006) J Natl Cancer Inst , vol.98 , Issue.10 , pp. 671-680
    • Holm, C.1    Rayala, S.2    Jirstrom, K.3    Stal, O.4    Kumar, R.5    Landberg, G.6
  • 4
    • 55349138386 scopus 로고    scopus 로고
    • ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer
    • PID: 18974135, COI: 1:CAS:528:DC%2BD1cXhtlSkur%2FL
    • Riggins RB, Lan JP, Zhu Y, Klimach U, Zwart A, Cavalli LR, et al. ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer. Cancer Res. 2008;68(21):8908–17. doi:10.1158/0008-5472.CAN-08-2669.
    • (2008) Cancer Res , vol.68 , Issue.21 , pp. 8908-8917
    • Riggins, R.B.1    Lan, J.P.2    Zhu, Y.3    Klimach, U.4    Zwart, A.5    Cavalli, L.R.6
  • 5
    • 70350072097 scopus 로고    scopus 로고
    • The role of X-box binding protein-1 in tumorigenicity
    • PID: 19609461, COI: 1:CAS:528:DC%2BD1MXhtF2kt7vO
    • Shajahan AN, Riggins RB, Clarke R. The role of X-box binding protein-1 in tumorigenicity. Drug News Perspect. 2009;22(5):241–6. doi:10.1358/dnp.2009.22.5.1378631.
    • (2009) Drug News Perspect , vol.22 , Issue.5 , pp. 241-246
    • Shajahan, A.N.1    Riggins, R.B.2    Clarke, R.3
  • 6
    • 2942544830 scopus 로고    scopus 로고
    • Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer
    • PID: 15193262, COI: 1:CAS:528:DC%2BD2cXltlGgsLo%3D
    • Michalides R, Griekspoor A, Balkenende A, Verwoerd D, Janssen L, Jalink K, et al. Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer. Cancer Cell. 2004;5(6):597–605. doi:10.1016/j.ccr.2004.05.016.
    • (2004) Cancer Cell , vol.5 , Issue.6 , pp. 597-605
    • Michalides, R.1    Griekspoor, A.2    Balkenende, A.3    Verwoerd, D.4    Janssen, L.5    Jalink, K.6
  • 7
    • 0035971181 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance
    • PID: 11139588, COI: 1:CAS:528:DC%2BD3MXis1Olu7k%3D
    • Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S, Nakshatri H. Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J Biol Chem. 2001;276(13):9817–24. doi:10.1074/jbc.M010840200.
    • (2001) J Biol Chem , vol.276 , Issue.13 , pp. 9817-9824
    • Campbell, R.A.1    Bhat-Nakshatri, P.2    Patel, N.M.3    Constantinidou, D.4    Ali, S.5    Nakshatri, H.6
  • 8
    • 41549097895 scopus 로고    scopus 로고
    • Cyclin D1 expression in breast cancer patients receiving adjuvant tamoxifen-based therapy
    • PID: 18347178, COI: 1:CAS:528:DC%2BD1cXjtlejur0%3D
    • Rudas M, Lehnert M, Huynh A, Jakesz R, Singer C, Lax S, et al. Cyclin D1 expression in breast cancer patients receiving adjuvant tamoxifen-based therapy. Clin Cancer Res. 2008;14(6):1767–74. doi:10.1158/1078-0432.CCR-07-4122.
    • (2008) Clin Cancer Res , vol.14 , Issue.6 , pp. 1767-1774
    • Rudas, M.1    Lehnert, M.2    Huynh, A.3    Jakesz, R.4    Singer, C.5    Lax, S.6
  • 9
    • 24744449148 scopus 로고    scopus 로고
    • Adverse effect of adjuvant tamoxifen in premenopausal breast cancer with cyclin D1 gene amplification
    • PID: 16140974
    • Jirstrom K, Stendahl M, Ryden L, Kronblad A, Bendahl PO, Stal O, et al. Adverse effect of adjuvant tamoxifen in premenopausal breast cancer with cyclin D1 gene amplification. Cancer Res. 2005;65(17):8009–16. doi:10.1158/0008-5472.CAN-05-0746.
    • (2005) Cancer Res , vol.65 , Issue.17 , pp. 8009-8016
    • Jirstrom, K.1    Stendahl, M.2    Ryden, L.3    Kronblad, A.4    Bendahl, P.O.5    Stal, O.6
  • 10
    • 35549002845 scopus 로고    scopus 로고
    • Amplification of CCND1 and PAK1 as predictors of recurrence and tamoxifen resistance in postmenopausal breast cancer
    • PID: 17486065, COI: 1:CAS:528:DC%2BD2sXht1Wgt7rJ
    • Bostner J, Ahnstrom Waltersson M, Fornander T, Skoog L, Nordenskjold B, Stal O. Amplification of CCND1 and PAK1 as predictors of recurrence and tamoxifen resistance in postmenopausal breast cancer. Oncogene. 2007;26(49):6997–7005. doi:10.1038/sj.onc.1210506.
    • (2007) Oncogene , vol.26 , Issue.49 , pp. 6997-7005
    • Bostner, J.1    Ahnstrom Waltersson, M.2    Fornander, T.3    Skoog, L.4    Nordenskjold, B.5    Stal, O.6
  • 11
    • 59449085778 scopus 로고    scopus 로고
    • Gene products of chromosome 11q and their association with CCND1 gene amplification and tamoxifen resistance in premenopausal breast cancer
    • PID: 18823530
    • Lundgren K, Holm K, Nordenskjold B, Borg A, Landberg G. Gene products of chromosome 11q and their association with CCND1 gene amplification and tamoxifen resistance in premenopausal breast cancer. Breast Cancer Res. 2008;10(5):R81. doi:10.1186/bcr2150.
    • (2008) Breast Cancer Res , vol.10 , Issue.5 , pp. 81
    • Lundgren, K.1    Holm, K.2    Nordenskjold, B.3    Borg, A.4    Landberg, G.5
  • 12
    • 9244222241 scopus 로고    scopus 로고
    • Prognostic relevance of gene amplifications and coamplifications in breast cancer
    • PID: 15574759, COI: 1:CAS:528:DC%2BD2cXhtVCjs7zJ
    • Al-Kuraya K, Schraml P, Torhorst J, Tapia C, Zaharieva B, Novotny H, et al. Prognostic relevance of gene amplifications and coamplifications in breast cancer. Cancer Res. 2004;64(23):8534–40. doi:10.1158/0008-5472.CAN-04-1945.
    • (2004) Cancer Res , vol.64 , Issue.23 , pp. 8534-8540
    • Al-Kuraya, K.1    Schraml, P.2    Torhorst, J.3    Tapia, C.4    Zaharieva, B.5    Novotny, H.6
  • 13
    • 33745190482 scopus 로고    scopus 로고
    • Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis
    • PID: 16648863, COI: 1:CAS:528:DC%2BD28Xls1KitLY%3D
    • Reis-Filho JS, Savage K, Lambros MB, James M, Steele D, Jones RL, et al. Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis. Mod Pathol. 2006;19(7):999–1009. doi:10.1038/modpathol.3800621.
    • (2006) Mod Pathol , vol.19 , Issue.7 , pp. 999-1009
    • Reis-Filho, J.S.1    Savage, K.2    Lambros, M.B.3    James, M.4    Steele, D.5    Jones, R.L.6
  • 14
    • 43149126354 scopus 로고    scopus 로고
    • CCND1 amplification and cyclin D1 expression in breast cancer and their relation with proteomic subgroups and patient outcome
    • Elsheikh S, Green AR, Aleskandarany MA, Grainge M, Paish CE, Lambros MB, et al. CCND1 amplification and cyclin D1 expression in breast cancer and their relation with proteomic subgroups and patient outcome. Breast Cancer Res Treat. 2006;109(2):325–35. doi:10.1007/s10549-007-9659-8.
    • (2006) Breast Cancer Res Treat , vol.109 , Issue.2 , pp. 325-335
    • Elsheikh, S.1    Green, A.R.2    Aleskandarany, M.A.3    Grainge, M.4    Paish, C.E.5    Lambros, M.B.6
  • 15
    • 0032771839 scopus 로고    scopus 로고
    • Overexpression of cyclin D1 messenger RNA predicts for poor prognosis in estrogen receptor-positive breast cancer
    • PID: 10473088, COI: 1:STN:280:DyaK1MvgtVSltQ%3D%3D
    • Kenny FS, Hui R, Musgrove EA, Gee JM, Blamey RW, Nicholson RI, et al. Overexpression of cyclin D1 messenger RNA predicts for poor prognosis in estrogen receptor-positive breast cancer. Clin Cancer Res. 1999;5(8):2069–76.
    • (1999) Clin Cancer Res , vol.5 , Issue.8 , pp. 2069-2076
    • Kenny, F.S.1    Hui, R.2    Musgrove, E.A.3    Gee, J.M.4    Blamey, R.W.5    Nicholson, R.I.6
  • 17
    • 0030745396 scopus 로고    scopus 로고
    • Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4
    • PID: 9271411, COI: 1:CAS:528:DyaK2sXlslartL0%3D
    • Neuman E, Ladha MH, Lin N, Upton TM, Miller SJ, DiRenzo J, et al. Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4. Mol Cell Biol. 1997;17(9):5338–47.
    • (1997) Mol Cell Biol , vol.17 , Issue.9 , pp. 5338-5347
    • Neuman, E.1    Ladha, M.H.2    Lin, N.3    Upton, T.M.4    Miller, S.J.5    DiRenzo, J.6
  • 18
    • 0029111934 scopus 로고
    • Cyclin D1 provides a link between development and oncogenesis in the retina and breast
    • PID: 7664341, COI: 1:CAS:528:DyaK2MXnvVWmtLc%3D
    • Sicinski P, Donaher JL, Parker SB, Li T, Fazeli A, Gardner H, et al. Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell. 1995;82(4):621–30.
    • (1995) Cell , vol.82 , Issue.4 , pp. 621-630
    • Sicinski, P.1    Donaher, J.L.2    Parker, S.B.3    Li, T.4    Fazeli, A.5    Gardner, H.6
  • 19
    • 0030964233 scopus 로고    scopus 로고
    • Inducible overexpression of cyclin D1 in breast cancer cells reverses the growth-inhibitory effects of antiestrogens
    • PID: 9815758, COI: 1:CAS:528:DyaK2sXkt1Ohs78%3D
    • Wilcken NR, Prall OW, Musgrove EA, Sutherland RL. Inducible overexpression of cyclin D1 in breast cancer cells reverses the growth-inhibitory effects of antiestrogens. Clin Cancer Res. 1997;3(6):849–54.
    • (1997) Clin Cancer Res , vol.3 , Issue.6 , pp. 849-854
    • Wilcken, N.R.1    Prall, O.W.2    Musgrove, E.A.3    Sutherland, R.L.4
  • 20
    • 2942533005 scopus 로고    scopus 로고
    • Cyclin D1 overexpression is a negative predictive factor for tamoxifen response in postmenopausal breast cancer patients
    • PID: 15138475, COI: 1:CAS:528:DC%2BD2cXjvVals7w%3D
    • Stendahl M, Kronblad A, Ryden L, Emdin S, Bengtsson NO, Landberg G. Cyclin D1 overexpression is a negative predictive factor for tamoxifen response in postmenopausal breast cancer patients. Br J Cancer. 2004;90(10):1942–8. doi:10.1038/sj.bjc.6601831.
    • (2004) Br J Cancer , vol.90 , Issue.10 , pp. 1942-1948
    • Stendahl, M.1    Kronblad, A.2    Ryden, L.3    Emdin, S.4    Bengtsson, N.O.5    Landberg, G.6
  • 21
    • 0036897326 scopus 로고    scopus 로고
    • Constitutive overexpression of cyclin D1 but not cyclin E confers acute resistance to antiestrogens in T-47D breast cancer cells
    • PID: 12460907, COI: 1:CAS:528:DC%2BD38XpsVahsL0%3D
    • Hui R, Finney GL, Carroll JS, Lee CS, Musgrove EA, Sutherland RL. Constitutive overexpression of cyclin D1 but not cyclin E confers acute resistance to antiestrogens in T-47D breast cancer cells. Cancer Res. 2002;62(23):6916–23.
    • (2002) Cancer Res , vol.62 , Issue.23 , pp. 6916-6923
    • Hui, R.1    Finney, G.L.2    Carroll, J.S.3    Lee, C.S.4    Musgrove, E.A.5    Sutherland, R.L.6
  • 22
    • 58149278847 scopus 로고    scopus 로고
    • Factors predicting failure of adjuvant hormonotherapy of breast carcinoma. A study in tamoxifen treated patients
    • PID: 19202962, COI: 1:STN:280:DC%2BD1M7ivFaltg%3D%3D
    • Petrakova K, Nenutil R, Grell P, Fabian P, Zichova I, Svoboda M, et al. Factors predicting failure of adjuvant hormonotherapy of breast carcinoma. A study in tamoxifen treated patients. Klin Onkol. 2008;21(5):303–8.
    • (2008) Klin Onkol , vol.21 , Issue.5 , pp. 303-308
    • Petrakova, K.1    Nenutil, R.2    Grell, P.3    Fabian, P.4    Zichova, I.5    Svoboda, M.6
  • 23
    • 34250882656 scopus 로고    scopus 로고
    • Cyclin D-1, interleukin-6, HER-2/neu, transforming growth factor receptor-II and prediction of relapse in women with early stage, hormone receptor-positive breast cancer treated with tamoxifen
    • PID: 17593037, COI: 1:CAS:528:DC%2BD2sXos1yktLc%3D
    • Muss HB, Bunn JY, Crocker A, Plaut K, Koh J, Heintz N, et al. Cyclin D-1, interleukin-6, HER-2/neu, transforming growth factor receptor-II and prediction of relapse in women with early stage, hormone receptor-positive breast cancer treated with tamoxifen. Breast J. 2007;13(4):337–45. doi:10.1111/j.1524-4741.2007.00440.x.
    • (2007) Breast J , vol.13 , Issue.4 , pp. 337-345
    • Muss, H.B.1    Bunn, J.Y.2    Crocker, A.3    Plaut, K.4    Koh, J.5    Heintz, N.6
  • 24
    • 18844443477 scopus 로고    scopus 로고
    • Role of cyclin D1 in ErbB2-positive breast cancer and tamoxifen resistance
    • PID: 15868442
    • Ahnstrom M, Nordenskjold B, Rutqvist LE, Skoog L, Stal O. Role of cyclin D1 in ErbB2-positive breast cancer and tamoxifen resistance. Breast Cancer Res Treat. 2005;91(2):145–51. doi:10.1007/s10549-004-6457-4.
    • (2005) Breast Cancer Res Treat , vol.91 , Issue.2 , pp. 145-151
    • Ahnstrom, M.1    Nordenskjold, B.2    Rutqvist, L.E.3    Skoog, L.4    Stal, O.5
  • 25
    • 1842834769 scopus 로고    scopus 로고
    • Cyclin D1 expression and patient outcome after tamoxifen therapy in estrogen receptor positive metastatic breast cancer
    • PID: 12469160, COI: 1:CAS:528:DC%2BD3sXpslKj
    • Han S, Park K, Bae BN, Kim KH, Kim HJ, Kim YD, et al. Cyclin D1 expression and patient outcome after tamoxifen therapy in estrogen receptor positive metastatic breast cancer. Oncol Rep. 2003;10(1):141–4.
    • (2003) Oncol Rep , vol.10 , Issue.1 , pp. 141-144
    • Han, S.1    Park, K.2    Bae, B.N.3    Kim, K.H.4    Kim, H.J.5    Kim, Y.D.6
  • 26
    • 33644787057 scopus 로고    scopus 로고
    • A multimarker model to predict outcome in tamoxifen-treated breast cancer patients
    • PID: 16489071, COI: 1:CAS:528:DC%2BD28XhsFaltL4%3D
    • Linke SP, Bremer TM, Herold CD, Sauter G, Diamond C. A multimarker model to predict outcome in tamoxifen-treated breast cancer patients. Clin Cancer Res. 2006;12(4):1175–83. doi:10.1158/1078-0432.CCR-05-1562.
    • (2006) Clin Cancer Res , vol.12 , Issue.4 , pp. 1175-1183
    • Linke, S.P.1    Bremer, T.M.2    Herold, C.D.3    Sauter, G.4    Diamond, C.5
  • 27
    • 0029893319 scopus 로고    scopus 로고
    • Cyclin D1 and prognosis in human breast cancer
    • PID: 8608989, COI: 1:STN:280:DyaK283gtFOitA%3D%3D
    • Gillett C, Smith P, Gregory W, Richards M, Millis R, Peters G, et al. Cyclin D1 and prognosis in human breast cancer. Int J Cancer. 1996;69(2):92–9. doi:10.1002/(SICI)1097-0215(19960422)69:2<92:AID-IJC4>3.0.CO;2-Q.
    • (1996) Int J Cancer , vol.69 , Issue.2 , pp. 92-99
    • Gillett, C.1    Smith, P.2    Gregory, W.3    Richards, M.4    Millis, R.5    Peters, G.6
  • 28
    • 0034652452 scopus 로고    scopus 로고
    • Relating genotype and phenotype in breast cancer: an analysis of the prognostic significance of amplification at eight different genes or loci and of p53 mutations
    • PID: 10706127, COI: 1:CAS:528:DC%2BD3cXhs1ShsLc%3D
    • Cuny M, Kramar A, Courjal F, Johannsdottir V, Iacopetta B, Fontaine H, et al. Relating genotype and phenotype in breast cancer: an analysis of the prognostic significance of amplification at eight different genes or loci and of p53 mutations. Cancer Res. 2000;60(4):1077–83.
    • (2000) Cancer Res , vol.60 , Issue.4 , pp. 1077-1083
    • Cuny, M.1    Kramar, A.2    Courjal, F.3    Johannsdottir, V.4    Iacopetta, B.5    Fontaine, H.6
  • 29
    • 0036514435 scopus 로고    scopus 로고
    • Expression and amplification of cyclin D1 in primary breast carcinomas: relationship with histopathological types and clinico-pathological parameters
    • PID: 11836618, COI: 1:CAS:528:DC%2BD38XitVCgsbk%3D
    • Naidu R, Wahab NA, Yadav MM, Kutty MK. Expression and amplification of cyclin D1 in primary breast carcinomas: relationship with histopathological types and clinico-pathological parameters. Oncol Rep. 2002;9(2):409–16.
    • (2002) Oncol Rep , vol.9 , Issue.2 , pp. 409-416
    • Naidu, R.1    Wahab, N.A.2    Yadav, M.M.3    Kutty, M.K.4
  • 30
    • 0029657594 scopus 로고    scopus 로고
    • Cyclin DI amplification is not associated with reduced overall survival in primary breast cancer but may predict early relapse in patients with features of good prognosis
    • PID: 9816285, COI: 1:STN:280:DyaK1M%2FjsFWgsQ%3D%3D
    • Seshadri R, Lee CS, Hui R, McCaul K, Horsfall DJ, Sutherland RL. Cyclin DI amplification is not associated with reduced overall survival in primary breast cancer but may predict early relapse in patients with features of good prognosis. Clin Cancer Res. 1996;2(7):1177–84.
    • (1996) Clin Cancer Res , vol.2 , Issue.7 , pp. 1177-1184
    • Seshadri, R.1    Lee, C.S.2    Hui, R.3    McCaul, K.4    Horsfall, D.J.5    Sutherland, R.L.6
  • 31
    • 53249123419 scopus 로고    scopus 로고
    • Clinical usefulness of EGFR gene copy number as a predictive marker in colorectal cancer patients treated with cetuximab: a fluorescent in situ hybridization study
    • PID: 18794099, COI: 1:CAS:528:DC%2BD1cXhtFaitrjP
    • Personeni N, Fieuws S, Piessevaux H, De Hertogh G, De Schutter J, Biesmans B, et al. Clinical usefulness of EGFR gene copy number as a predictive marker in colorectal cancer patients treated with cetuximab: a fluorescent in situ hybridization study. Clin Cancer Res. 2008;14(18):5869–76. doi:10.1158/1078-0432.CCR-08-0449.
    • (2008) Clin Cancer Res , vol.14 , Issue.18 , pp. 5869-5876
    • Personeni, N.1    Fieuws, S.2    Piessevaux, H.3    De Hertogh, G.4    De Schutter, J.5    Biesmans, B.6
  • 32
    • 34247634643 scopus 로고    scopus 로고
    • Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer
    • PID: 17417639, COI: 1:CAS:528:DC%2BD2sXksFersLs%3D
    • Holst F, Stahl PR, Ruiz C, Hellwinkel O, Jehan Z, Wendland M, et al. Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. Nat Genet. 2007;39(5):655–60. doi:10.1038/ng2006.
    • (2007) Nat Genet , vol.39 , Issue.5 , pp. 655-660
    • Holst, F.1    Stahl, P.R.2    Ruiz, C.3    Hellwinkel, O.4    Jehan, Z.5    Wendland, M.6
  • 33
    • 10744232226 scopus 로고    scopus 로고
    • High-throughput tissue microarray analysis of 11q13 gene amplification (CCND1, FGF3, FGF4, EMS1) in urinary bladder cancer
    • PID: 14648664, COI: 1:CAS:528:DC%2BD2cXlsVGmtQ%3D%3D
    • Zaharieva BM, Simon R, Diener PA, Ackermann D, Maurer R, Alund G, et al. High-throughput tissue microarray analysis of 11q13 gene amplification (CCND1, FGF3, FGF4, EMS1) in urinary bladder cancer. J Pathol. 2003;201(4):603–8. doi:10.1002/path.1481.
    • (2003) J Pathol , vol.201 , Issue.4 , pp. 603-608
    • Zaharieva, B.M.1    Simon, R.2    Diener, P.A.3    Ackermann, D.4    Maurer, R.5    Alund, G.6
  • 34
    • 61449122221 scopus 로고    scopus 로고
    • Frequent amplifications and deletions of G1/S-phase transition genes, CCND1 and MYC in early breast cancers: a potential role in G1/S escape
    • PID: 19242061, COI: 1:CAS:528:DC%2BD1MXkvVWru7k%3D
    • Jensen LB, Bartlett JM, Witton CJ, Kirkegaard T, Brown S, Muller S, et al. Frequent amplifications and deletions of G1/S-phase transition genes, CCND1 and MYC in early breast cancers: a potential role in G1/S escape. Cancer Biomark. 2009;5(1):41–9. doi:10.3233/CBM-2009-0570.
    • (2009) Cancer Biomark , vol.5 , Issue.1 , pp. 41-49
    • Jensen, L.B.1    Bartlett, J.M.2    Witton, C.J.3    Kirkegaard, T.4    Brown, S.5    Muller, S.6
  • 35
    • 0028710411 scopus 로고
    • Int-2/FGF3 amplification is a better independent predictor of relapse than c-myc and c-erbB-2/neu amplifications in primary human breast cancer
    • PID: 7892157, COI: 1:STN:280:DyaK2M7pvFaitg%3D%3D
    • Champeme MH, Bieche I, Hacene K, Lidereau R. Int-2/FGF3 amplification is a better independent predictor of relapse than c-myc and c-erbB-2/neu amplifications in primary human breast cancer. Mod Pathol. 1994;7(9):900–5.
    • (1994) Mod Pathol , vol.7 , Issue.9 , pp. 900-905
    • Champeme, M.H.1    Bieche, I.2    Hacene, K.3    Lidereau, R.4
  • 37
    • 0035421454 scopus 로고    scopus 로고
    • Patterns of her-2/neu amplification and overexpression in primary and metastatic breast cancer
    • PID: 11481385, COI: 1:CAS:528:DC%2BD3MXmtVGqsLc%3D
    • Simon R, Nocito A, Hubscher T, Bucher C, Torhorst J, Schraml P, et al. Patterns of her-2/neu amplification and overexpression in primary and metastatic breast cancer. J Natl Cancer Inst. 2001;93(15):1141–6.
    • (2001) J Natl Cancer Inst , vol.93 , Issue.15 , pp. 1141-1146
    • Simon, R.1    Nocito, A.2    Hubscher, T.3    Bucher, C.4    Torhorst, J.5    Schraml, P.6
  • 38
    • 0033973884 scopus 로고    scopus 로고
    • Determination of Her-2/Neu status in breast carcinoma: comparative analysis of immunohistochemistry and fluorescent in situ hybridization
    • PID: 10658908, COI: 1:STN:280:DC%2BD3c7it1Siug%3D%3D
    • Jimenez RE, Wallis T, Tabasczka P, Visscher DW. Determination of Her-2/Neu status in breast carcinoma: comparative analysis of immunohistochemistry and fluorescent in situ hybridization. Mod Pathol. 2000;13(1):37–45. doi:10.1038/modpathol.3880007.
    • (2000) Mod Pathol , vol.13 , Issue.1 , pp. 37-45
    • Jimenez, R.E.1    Wallis, T.2    Tabasczka, P.3    Visscher, D.W.4
  • 39
    • 0033868761 scopus 로고    scopus 로고
    • Assessment of Her-2/neu overexpression in primary breast cancers and their metastatic lesions: an immunohistochemical study
    • PID: 10945565, COI: 1:CAS:528:DC%2BD3cXmtVeqtLg%3D
    • Masood S, Bui MM. Assessment of Her-2/neu overexpression in primary breast cancers and their metastatic lesions: an immunohistochemical study. Ann Clin Lab Sci. 2000;30(3):259–65.
    • (2000) Ann Clin Lab Sci , vol.30 , Issue.3 , pp. 259-265
    • Masood, S.1    Bui, M.M.2
  • 40
    • 0027207207 scopus 로고
    • Relationship of c-myc amplification to progression of breast cancer from in situ to invasive tumor and lymph node metastasis
    • PID: 8492318, COI: 1:STN:280:DyaK3s3mtVOhtA%3D%3D
    • Watson PH, Safneck JR, Le K, Dubik D, Shiu RP. Relationship of c-myc amplification to progression of breast cancer from in situ to invasive tumor and lymph node metastasis. J Natl Cancer Inst. 1993;85(11):902–7.
    • (1993) J Natl Cancer Inst , vol.85 , Issue.11 , pp. 902-907
    • Watson, P.H.1    Safneck, J.R.2    Le, K.3    Dubik, D.4    Shiu, R.P.5
  • 41
    • 0035053050 scopus 로고    scopus 로고
    • Amplification of growth regulatory genes in intraductal breast cancer is associated with higher nuclear grade but not with the progression to invasiveness
    • PID: 11304576, COI: 1:CAS:528:DC%2BD3MXjsFSisbg%3D
    • Glockner S, Lehmann U, Wilke N, Kleeberger W, Langer F, Kreipe H. Amplification of growth regulatory genes in intraductal breast cancer is associated with higher nuclear grade but not with the progression to invasiveness. Lab Invest. 2001;81(4):565–71.
    • (2001) Lab Invest , vol.81 , Issue.4 , pp. 565-571
    • Glockner, S.1    Lehmann, U.2    Wilke, N.3    Kleeberger, W.4    Langer, F.5    Kreipe, H.6
  • 42
    • 79952568983 scopus 로고    scopus 로고
    • Molecular differences between ductal carcinoma in situ and adjacent invasive breast carcinoma: a multiplex ligation-dependent probe amplification study
    • COI: 1:CAS:528:DC%2BC3cXhsVGrs7nM
    • Moelans CB, de Weger RA, Monsuur HN, Maes AH, van Diest PJ. Molecular differences between ductal carcinoma in situ and adjacent invasive breast carcinoma: a multiplex ligation-dependent probe amplification study. Anal Cell Pathol (Amst). 2010;33(3):165–73. doi:10.3233/ACP-CLO-2010-0546.
    • (2010) Anal Cell Pathol (Amst) , vol.33 , Issue.3 , pp. 165-173
    • Moelans, C.B.1    de Weger, R.A.2    Monsuur, H.N.3    Maes, A.H.4    van Diest, P.J.5
  • 43
    • 0036798620 scopus 로고    scopus 로고
    • Marked intratumoral heterogeneity of c-myc and cyclinD1 but not of c-erbB2 amplification in breast cancer
    • PID: 12379776
    • Glockner S, Buurman H, Kleeberger W, Lehmann U, Kreipe H. Marked intratumoral heterogeneity of c-myc and cyclinD1 but not of c-erbB2 amplification in breast cancer. Lab Invest. 2002;82(10):1419–26.
    • (2002) Lab Invest , vol.82 , Issue.10 , pp. 1419-1426
    • Glockner, S.1    Buurman, H.2    Kleeberger, W.3    Lehmann, U.4    Kreipe, H.5
  • 44
    • 0035421454 scopus 로고    scopus 로고
    • Patterns of her-2/neu amplification and overexpression in primary and metastatic breast cancer
    • PID: 11481385, COI: 1:CAS:528:DC%2BD3MXmtVGqsLc%3D
    • Simon R, Nocito A, Hubscher T, Bucher C, Torhorst J, Schraml P, et al. Patterns of her-2/neu amplification and overexpression in primary and metastatic breast cancer. J Natl Cancer Inst. 2001;93(15):1141–6.
    • (2001) J Natl Cancer Inst , vol.93 , Issue.15 , pp. 1141-1146
    • Simon, R.1    Nocito, A.2    Hubscher, T.3    Bucher, C.4    Torhorst, J.5    Schraml, P.6
  • 45
    • 84871922832 scopus 로고    scopus 로고
    • Marked heterogeneity of ERG expression in large primary prostate cancers
    • Minner S, Gartner M, Freudenthaler F, Bauer M, Kluth M, Salomon G, et al. Marked heterogeneity of ERG expression in large primary prostate cancers. Modern Path. 2012;1:106–16. doi:10.1038/modpathol.2012.130.
    • (2012) Modern Path , vol.1 , pp. 106-116
    • Minner, S.1    Gartner, M.2    Freudenthaler, F.3    Bauer, M.4    Kluth, M.5    Salomon, G.6
  • 46
    • 38049008135 scopus 로고    scopus 로고
    • Comprehensive epidermal growth factor receptor gene analysis from cytological specimens of non-small-cell lung cancers
    • PID: 18087280, COI: 1:CAS:528:DC%2BD1cXisF2rsA%3D%3D
    • Savic S, Tapia C, Grilli B, Rufle A, Bihl MP, De Vito Barascud A, et al. Comprehensive epidermal growth factor receptor gene analysis from cytological specimens of non-small-cell lung cancers. Br J Cancer. 2008;98(1):154–60. doi:10.1038/sj.bjc.6604142.
    • (2008) Br J Cancer , vol.98 , Issue.1 , pp. 154-160
    • Savic, S.1    Tapia, C.2    Grilli, B.3    Rufle, A.4    Bihl, M.P.5    De Vito Barascud, A.6
  • 47
    • 0035367084 scopus 로고    scopus 로고
    • Discordance between K-ras mutations in bone marrow micrometastases and the primary tumor in colorectal cancer
    • PID: 11387355, COI: 1:CAS:528:DC%2BD3MXltVGgs7g%3D
    • Tortola S, Steinert R, Hantschick M, Peinado MA, Gastinger I, Stosiek P, et al. Discordance between K-ras mutations in bone marrow micrometastases and the primary tumor in colorectal cancer. J Clin Oncol. 2001;19(11):2837–43.
    • (2001) J Clin Oncol , vol.19 , Issue.11 , pp. 2837-2843
    • Tortola, S.1    Steinert, R.2    Hantschick, M.3    Peinado, M.A.4    Gastinger, I.5    Stosiek, P.6
  • 48
    • 67849090836 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene in primary tumor and metastatic sites from non-small cell lung cancer
    • PID: 19404216
    • Daniele L, Cassoni P, Bacillo E, Cappia S, Righi L, Volante M, et al. Epidermal growth factor receptor gene in primary tumor and metastatic sites from non-small cell lung cancer. J Thorac Oncol. 2009;4(6):684–8. doi:10.1097/JTO.0b013e3181a52359.
    • (2009) J Thorac Oncol , vol.4 , Issue.6 , pp. 684-688
    • Daniele, L.1    Cassoni, P.2    Bacillo, E.3    Cappia, S.4    Righi, L.5    Volante, M.6
  • 49
    • 71049185583 scopus 로고    scopus 로고
    • A comparison of EGFR and KRAS status in primary lung carcinoma and matched metastases
    • PID: 19740513, COI: 1:CAS:528:DC%2BD1MXhsFais7%2FO
    • Monaco SE, Nikiforova MN, Cieply K, Teot LA, Khalbuss WE, Dacic S. A comparison of EGFR and KRAS status in primary lung carcinoma and matched metastases. Hum Pathol. 2010;41(1):94–102. doi:10.1016/j.humpath.2009.06.019.
    • (2010) Hum Pathol , vol.41 , Issue.1 , pp. 94-102
    • Monaco, S.E.1    Nikiforova, M.N.2    Cieply, K.3    Teot, L.A.4    Khalbuss, W.E.5    Dacic, S.6
  • 50
    • 0027215064 scopus 로고
    • Heterogeneity of erbB-2 gene amplification in bladder cancer
    • PID: 8097962, COI: 1:STN:280:DyaK3s3ltFCgtA%3D%3D
    • Sauter G, Moch H, Moore D, Carroll P, Kerschmann R, Chew K, et al. Heterogeneity of erbB-2 gene amplification in bladder cancer. Cancer Res. 1993;53(10 Suppl):2199–203.
    • (1993) Cancer Res , vol.53 , pp. 2199-2203
    • Sauter, G.1    Moch, H.2    Moore, D.3    Carroll, P.4    Kerschmann, R.5    Chew, K.6
  • 51
    • 77957953603 scopus 로고    scopus 로고
    • Heterogenous high-level HER-2 amplification in a small subset of colorectal cancers
    • PID: 20656317, COI: 1:CAS:528:DC%2BC3cXhtlSqurjJ
    • Marx AH, Burandt EC, Choschzick M, Simon R, Yekebas E, Kaifi JT, et al. Heterogenous high-level HER-2 amplification in a small subset of colorectal cancers. Hum Pathol. 2010;41(11):1577–85. doi:10.1016/j.humpath.2010.02.018.
    • (2010) Hum Pathol , vol.41 , Issue.11 , pp. 1577-1585
    • Marx, A.H.1    Burandt, E.C.2    Choschzick, M.3    Simon, R.4    Yekebas, E.5    Kaifi, J.T.6
  • 52
    • 67349222954 scopus 로고    scopus 로고
    • HER-2 amplification is highly homogenous in gastric cancer
    • Marx AH, Tharun L, Muth J, Dancau AM, Simon R, Yekebas E, et al. HER-2 amplification is highly homogenous in gastric cancer. Hum Pathol. 2010;40(6):769–77. doi:10.1016/j.humpath.2008.11.014.
    • (2010) Hum Pathol , vol.40 , Issue.6 , pp. 769-777
    • Marx, A.H.1    Tharun, L.2    Muth, J.3    Dancau, A.M.4    Simon, R.5    Yekebas, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.