Transcranial direct current stimulation and neuroplasticity genes: Implications for psychiatric disorders

Acta Neuropsychiatrica

Volumn 28, Issue 1, 2015, Pages 1-10

  Chhabra, Harleen ^a   Shivakumar, Venkataram ^a   Agarwal, Sri Mahavir ^a   Bose, Anushree ^a   Venugopal, Deepthi ^a   Rajasekaran, Ashwini ^a   Subbanna, Manjula ^a   Kalmady, Sunil V ^a   Narayanaswamy, Janardhanan C ^a   Debnath, Monojit ^a   Venkatasubramanian, Ganesan ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

Author keywords

genes; neuroplasticity; schizophrenia; tDCS

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CATECHOL METHYLTRANSFERASE; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; GLUTAMATE RECEPTOR; NEUROGENIN 1;

BDNF GENE; BRAIN BLOOD FLOW; COMT GENE; CORTICAL EXCITABILITY; DORSOLATERAL PREFRONTAL CORTEX; EVOKED MUSCLE RESPONSE; EXCITABILITY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; LONG TERM POTENTIATION; MAJOR DEPRESSION; MENTAL DISEASE; NERVE CELL PLASTICITY; NEUROMODULATION; NONHUMAN; REVIEW; SCHIZOPHRENIA; SYSTEMATIC REVIEW; TRANSCRANIAL DIRECT CURRENT STIMULATION; ANIMAL; DISEASE MODEL; GENETIC VARIATION; GENETICS; MENTAL DISORDERS; PHYSIOLOGY; PROCEDURES; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; DISEASE MODELS, ANIMAL; GENETIC VARIATION; HUMANS; MENTAL DISORDERS; NEURONAL PLASTICITY; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; TRANSCRANIAL DIRECT CURRENT STIMULATION;

EID: 84952875699     PISSN: 09242708     EISSN: 16015215     Source Type: Journal    
DOI: 10.1017/neu.2015.20     Document Type: Review

References (96)

1. HAHN C, RICE J, MACUFF S, MINHAS P, RAHMAN A, BIKSON M. Methods for extra-low voltage transcranial direct current stimulation: current and time dependent impedance decreases. Clin Neurophysiol 2013;124:551-556.
2. NITSCHE MA, PAULUS W. Transcranial direct current stimulation - update 2011. Restor Neurol Neurosci 2011; 29:463-492.
3. KRAUSE B, MARQUEZ-RUIZ J, KADOSH RC. The effect of transcranial direct current stimulation: a role for cortical excitation/inhibition balance? Front Hum Neurosci 2013;7:602.
4. AGARWAL SM, SHIVAKUMAR V, BOSE A et al. Transcranial direct current stimulation in schizophrenia - a review. Clinical Psychopharmacol Neurosci 2013;11:118-125.
5. BRUNONI AR, SHIOZAWA P, TRUONG D et al. Understanding tDCS effects in schizophrenia: a systematic review of clinical data and an integrated computation modeling analysis. Expert Rev Med Devices 2014;11:383-394.
6. NARAYANASWAMY JC, SHIVAKUMAR V, BOSE A, AGARWAL SM, VENKATASUBRAMANIAN G, GANGADHAR BN. Sustained improvement of negative symptoms in schizophrenia with add-on tDCS. Clin Schizophr Relat Psychoses 2014;20:1-7.
7. BRUNELIN J, MONDINO M, GASSAB L et al. Examining transcranial direct-current stimulation (tDCS) as a treatment for hallucinations in schizophrenia. Am J Psychiatry 2012;169:719-724.
8. RAKESH G, SHIVAKUMAR V, SUBRAMANIAM A et al. Monotherapy with tDCS for schizophrenia: a case report. Brain Stimul 2013;6:708-709.
9. SHIVAKUMAR V, BOSE A, RAKESH G et al. Rapid improvement of auditory verbal hallucinations in schizophrenia after add-on treatment with transcranial direct-current stimulation. J ECT 2013;29:e43-e44.
10. BOSE A, SHIVAKUMAR V, NARAYANASWAMY JC et al. Insight facilitation with add-on tDCS in schizophrenia. Schizophr Res 2014;156:63-65.
11. NAWANI H, BOSE A, AGARWAL SM et al. Modulation of corollary discharge dysfunction in schizophrenia by tDCS: preliminary evidence. Brain Stimul 2014;7:486-488.
12. NAWANI H, KALMADY SV, BOSE A et al. Neural basis of tDCS effects on auditory verbal hallucinations in schizophrenia: a case report evidence for cortical neuroplasticity modulation. J ECT 2014;30:e2-e4.
13. KANDEL ER, PITTENGER C. The past, the future and the biology of memory storage. Philos Trans R Soc Lond B Biol Sci 1999;354:2027-2052.
14. KANDEL ER. The molecular biology of memory storage: a dialog between genes and synapses. Biosci Rep 2004;24:475-522.
15. SIBILLE E. Molecular aging of the brain, neuroplasticity, and vulnerability to depression and other brain-related disorders. Dialogues Clin Neurosci 2013;15:53-65.
16. VOINESKOS D, ROGASCH NC, RAJJI TK, FITZGERALD PB, DASKALAKIS ZJ. A review of evidence linking disrupted neural plasticity to schizophrenia. Can J Psychiatry 2013;58:86-92.
17. BALU DT, COYLE JT. Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia. Neurosci Biobehav Rev 2011;35:848-870.
18. NAKATA K, LIPSKA BK, HYDE TM et al. DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms. Proc Natl Acad Sci U S A 2009;106: 15873-15878.
19. BAILEY CH, BARTSCH D, KANDEL ER. Toward a molecular definition of long-term memory storage. Proc Natl Acad Sci U S A 1996;93:13445-13452.
20. GUO AY, SUN J, RILEY BP, THISELTON DL, KENDLER KS, ZHAO Z. The dystrobrevin-binding protein 1 gene: features and networks. Mol Psychiatry 2009;14:18-29.
21. ALIZADEH F, TABATABAIEFAR MA, GHADIRI M, YEKANINEJAD MS, JALILIAN N, NOORI-DALOII MR. Association of P1635 and P1655 polymorphisms in dysbindin (DTNBP1) gene with schizophrenia. Acta Neuropsychiatrica 2012;24:155-159.
22. DESBONNET L, WADDINGTON JL, O'TUATHAIGH CM. Mutant models for genes associated with schizophrenia. Biochem Soc Trans 2009;37(Pt 1):308-312.
23. JONSSON EG, EDMAN-AHLBOM B, SILLEN A et al. Brainderived neurotrophic factor gene (BDNF) variants and schizophrenia: an association study. Prog Neuropsychopharmacol Biol Psychiatry 2006;30:924-933.
24. ALLEN NC, BAGADE S, MCQUEEN MB et al. Systematic metaanalyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet 2008;40:827-834.
25. HASAN A, MISEWITSCH K, NITSCHE MA et al. Impaired motor cortex responses in non-psychotic first-degree relatives of schizophrenia patients: a cathodal tDCS pilot study. Brain Stimul 2013;6:821-829.
26. HASAN A, NITSCHE MA, HERRMANN M et al. Impaired longterm depression in schizophrenia: a cathodal tDCS pilot study. Brain Stimul 2012;5:475-483.
27. HASAN A, WOBROCK T, RAJJI T, MALCHOW B, DASKALAKIS ZJ. Modulating neural plasticity with non-invasive brain stimulation in schizophrenia. Eur Arch Psychiatry Clin Neurosci 2013;263:621-631. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/24061608.
28. LOO CK, ALONZO A, MARTIN D, MITCHELL PB, GALVEZ V, SACHDEV P. Transcranial direct current stimulation for depression: 3-week, randomised, sham-controlled trial. Br J Psychiatry 2012;200:52-59.
29. BRUNONI AR, FERRUCCI R, BORTOLOMASI M et al. Transcranial direct current stimulation (tDCS) in unipolar vs. bipolar depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry 2011;35:96-101.
30. FERRUCCI R, BORTOLOMASI M, VERGARI M et al. Transcranial direct current stimulation in severe, drug-resistant major depression. J Affect Disord 2009;118:215-219.
31. KLAUSS J, PENIDO PINHEIRO LC, SILVA MERLO BL et al. A randomized controlled trial of targeted prefrontal cortex modulation with tDCS in patients with alcohol dependence. Int J Neuropsychopharmacol 2014;17:1793-1803.
32. BOGGIO PS, ZAGHI S, VILLANI AB, FECTEAU S, PASCUAL-LEONE A, FREGNI F. Modulation of risk-taking in marijuana users by transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (DLPFC). Drug Alcohol Depend 2010;112:220-225.
33. DA SILVA MC, CONTI CL, KLAUSS J et al. Behavioral effects of transcranial direct current stimulation (tDCS) induced dorsolateral prefrontal cortex plasticity in alcohol dependence. J Physiol Paris 2013;107:493-502.
34. SHIOZAWA P, LEIVA AP, CASTRO CD et al. Transcranial direct current stimulation for generalized anxiety disorder: a case study. Biol Psychiatry 2014;75:e17-e18.
35. NARAYANASWAMY JC, JOSE D, CHHABRA H et al. Successful application of add-on transcranial direct current stimulation (tDCS) for treatment of SSRI resistant OCD. Brain Stimul 2014.
36. FERRUCCI R, MAMELI F, GUIDI I et al. Transcranial direct current stimulation improves recognition memory in Alzheimer disease. Neurology 2008;71:493-498.
37. KNABLE MB, BARCI BM, BARTKO JJ, WEBSTER MJ, TORREY EF. Molecular abnormalities in the major psychiatric illnesses: classification and regression tree (CRT) analysis of post-mortem prefrontal markers. Mol Psychiatry 2002;7:392-404.
38. SPEDDING M, NEAU I, HARSING L. Brain plasticity and pathology in psychiatric disease: sites of action for potential therapy. Current Opin Pharmacology 2003;3:33-40.
39. PLAYER MJ, TAYLOR JL, WEICKERT CS et al. Increase in PAS-induced neuroplasticity after a treatment course of transcranial direct current stimulation for depression. J Affect Disord 2014;167:140-147.
40. KRAUSE B, MARQUEZ-RUIZ J, COHEN KADOSH R. The effect of transcranial direct current stimulation: a role for cortical excitation/inhibition balance? Front Hum Neurosci 2013;7:602.
41. FRITSCH B, REIS J, MARTINOWICH K et al. Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning. Neuron 2010;66:198-204.
42. BIKSON M, INOUE M, AKIYAMA H et al. Effects of uniform extracellular DC electric fields on excitability in rat hippocampal slices in vitro. J Physiol 2004;557(Pt 1):175-190.
43. HASAN A, NITSCHE MA, REIN B et al. Dysfunctional longterm potentiation-like plasticity in schizophrenia revealed by transcranial direct current stimulation. Behav Brain Res 2011;224:15-22.
44. NITSCHE MAA, LIEBETANZ D, LANG N, TERGAU F, PAULUS W. Induction and modulation of neuroplasticity by transcranial direct current stimulation. In: Marcolin MA, Padberg F, editors. Transcranial brain stimulation for treatment of psychiatric disorders. Basel: Karger, 2007;23:172-186.
45. NITSCHE MA, PAULUS W. Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans. Neurology 2001;57:1899-1901.
46. JIANG T, XU RX, ZHANG AW et al. Effects of transcranial direct current stimulation on hemichannel pannexin-1 and neural plasticity in rat model of cerebral infarction. Neuroscience 2012;226:421-426.
47. YOON KJ, OH BM, KIM DY. Functional improvement and neuroplastic effects of anodal transcranial direct current stimulation (tDCS) delivered 1 day vs. 1 week after cerebral ischemia in rats. Brain Res 2012;1452:61-72.
48. KIMOTO S, BAZMI HH, LEWIS DA. Lower expression of glutamic acid decarboxylase 67 in the prefrontal cortex in schizophrenia: contribution of altered regulation by Zif268. Am J Psychiatry 2014;171:969-978.
49. VAISANEN J, IHALAINEN J, TANILA H, CASTREN E. Effects of NMDA-receptor antagonist treatment on c-fos expression in rat brain areas implicated in schizophrenia. Cell Mol Neurobiol 2004;24:769-780.
50. RANIERI F, PODDA MV, RICCARDI E et al. Modulation of LTP at rat hippocampal CA3-CA1 synapses by direct current stimulation. J Neurophysiol 2012;107:1868-1880.
51. LIEBETANZ D, NITSCHE MA, TERGAU F, PAULUS W. Pharmacological approach to the mechanisms of transcranial DC-stimulation-induced after-effects of human motor cortex excitability. Brain 2002;125(Pt 10):2238-2247.
52. NITSCHE MA, FRICKE K, HENSCHKE U et al. Pharmacological modulation of cortical excitability shifts induced by transcranial direct current stimulation in humans. J Physiol 2003;553(Pt 1):293-301.
53. GOODWILL AM, REYNOLDS J, DALY RM, KIDGELL DJ. Formation of cortical plasticity in older adults following tDCS and motor training. Front Aging Neurosci 2013;5:87.
54. MONTE-SILVA K, KUO MF, HESSENTHALER S et al. Induction of late LTP-like plasticity in the human motor cortex by repeated non-invasive brain stimulation. Brain Stimul 2013;6:424-432.
55. FREGNI F, BOGGIO PS, NITSCHE M et al. Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory. Exp Brain Res 2005;166:23-30.
56. ANTAL A, PAULUS W, NITSCHE MA. Electrical stimulation and visual network plasticity. Restor Neurol Neurosci 2011;29:365-374. (Review).
57. MONTE-SILVA K, KUO MF, HESSENTHALER S et al. Induction of late LTP-like plasticity in the human motor cortex by repeated non-invasive brain stimulation. Brain Stimul 2013;6:424-432.
58. KIRIMOTO H, OGATA K, ONISHI H, OYAMA M, GOTO Y, TOBIMATSU S. Transcranial direct current stimulation over the motor association cortex induces plastic changes in ipsilateral primary motor and somatosensory cortices. Clin Neurophysiol 2011;122:777-783.
59. KIDGELL DJ, GOODWILL AM, FRAZER AK, DALY RM. Induction of cortical plasticity and improved motor performance following unilateral and bilateral transcranial direct current stimulation of the primary motor cortex. BMC Neurosci 2013;14:64.
60. VENKATAKRISHNAN A, SANDRINI M. Combining transcranial direct current stimulation and neuroimaging: novel insights in understanding neuroplasticity. J Neurophysiol 2012;107:1-4.
61. LANG N, SIEBNER HR, WARD NS et al. How does transcranial DC stimulation of the primary motor cortex alter regional neuronal activity in the human brain? Eur J Neurosci 2005;22:495-504.
62. POLANIA R, PAULUS W, ANTAL A, NITSCHE MA. Introducing graph theory to track for neuroplastic alterations in the resting human brain: a transcranial direct current stimulation study. Neuroimage 2011;54:2287-2296.
63. KHAN B, HODICS T, HERVEY N, KONDRASKE G, STOWE AM, ALEXANDRAKIS G. Functional near-infrared spectroscopy maps cortical plasticity underlying altered motor performance induced by transcranial direct current stimulation. J Biomed Opt 2013;18:116003.
64. HUNTER MA, COFFMAN BA, TRUMBO MC, CLARK VP. Tracking the neuroplastic changes associated with transcranial direct current stimulation: a push for multimodal imaging. Front Hum Neurosci 2013;7:495.
65. PENA-GOMEZ C, SALA-LONCH R, JUNQUE C et al. Modulation of large-scale brain networks by transcranial direct current stimulation evidenced by resting-state functional MRI. Brain Stimul 2012;5:252-263.
66. PRATHIKANTI S, WEINBERGER DR. Psychiatric genetics - the new era: genetic research and some clinical implications. Br Med Bull 2005;73-74:107-122.
67. WEAVER SM, PORTELLI JN, CHAU A, CRISTOFORI I, MORETTI L, GRAFMAN J. Genetic polymorphisms and traumatic brain injury: the contribution of individual differences to recovery. Brain Imaging Behav 2012;8:420-434.
68. NIETO R, KUKULJAN M, SILVA H. BDNF and schizophrenia: from neurodevelopment to neuronal plasticity, learning, and memory. Front Psychiatry 2013;4:45.
69. SINGH JP, VOLAVKA J, CZOBOR P, VAN DORN RA. A metaanalysis of the Val158Met COMT polymorphism and violent behavior in schizophrenia. PLoS One 2012;7:e43423.
70. IRA E, ZANONI M, RUGGERI M, DAZZAN P, TOSATO S. COMT, neuropsychological function and brain structure in schizophrenia: a systematic review and neurobiological interpretation. J Psychiatry Neurosci 2013;38:366-380.
71. YANG XX, ZHU AN, LI FX, ZHANG ZX, LI M. Neurogenic locus notch homolog protein 4 and brain-derived neurotrophic factor variants combined effect on schizophrenia susceptibility. Acta Neuropsychiatr 2013; 25:356-360.
72. ANTAL A, CHAIEB L, MOLIADZE V et al. Brain-derived neurotrophic factor (BDNF) gene polymorphisms shape cortical plasticity in humans. Brain Stimul 2010;3:230-237.
73. DI LAZZARO V, MANGANELLI F, DILEONE M et al. The effects of prolonged cathodal direct current stimulation on the excitatory and inhibitory circuits of the ipsilateral and contralateral motor cortex. J Neural Transm 2012; 119:1499-1506.
74. BRUNONI AR, KEMP AH, SHIOZAWA P et al. Impact of 5-HTTLPR and BDNF polymorphisms on response to sertraline versus transcranial direct current stimulation: implications for the serotonergic system. Eur Neuropsychopharmacol 2013;23:1530-1540.
75. FUJIYAMA H, HYDE J, HINDER MR et al. Delayed plastic responses to anodal tDCS in older adults. Front Aging Neurosci 2014;6:115.
76. TEO JT, BENTLEY G, LAWRENCE P et al. Late cortical plasticity in motor and auditory cortex: role of met-allele in BDNF Val66Met polymorphism. Int J Neuropsychopharmacol 2014;17:705-713.
77. PLEWNIA C, ZWISSLER B, LANGST I, MAURER B, GIEL K, KRUGER R. Effects of transcranial direct current stimulation (tDCS) on executive functions: influence of COMT Val/Met polymorphism. Cortex 2013;49:1801-1807.
78. ARNSTEN AF, PASPALAS CD, GAMO NJ, YANG Y, WANG M. Dynamic network connectivity: a new form of neuroplasticity. Trends Cogn Sci 2010;14:365-375.
79. CHAKRAVARTY MM, FELSKY D, TAMPAKERAS M et al. DISC1 and striatal volume: a potential risk phenotype for mental illness. Front Psychiatry 2012;3:57.
80. GREENWOOD TA, LIGHT GA, SWERDLOW NR, RADANT AD, BRAFF DL. Association analysis of 94 candidate genes and schizophrenia-related endophenotypes. PLoS One 2012;7: e29630.
81. JUHASZ G, DUNHAM JS, MCKIE S et al. The CREB1-BDNFNTRK2 pathway in depression: multiple gene-cognitionenvironment interactions. Biol Psychiatry 2011;69:762-771.
82. SHYN SI, HAMILTON SP. The genetics of major depression: moving beyond the monoamine hypothesis. Psychiatr Clin North Am 2010;33:125-140.
83. DICK DM, JONES K, SACCONE N et al. Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism. Behav Genet 2006;36:112-126.
84. FERREIRA MA, O'DONOVAN MC, MENG YA et al. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet 2008;40:1056-1058.
85. SCHULZE TG, DETERA-WADLEIGH SD, AKULA N et al. Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder. Mol Psychiatry 2009;14: 487-491.
86. SMITH KR, KOPEIKINA KJ, FAWCETT-PATEL JM et al. Psychiatric risk factor ANK3/ankyrin-G nanodomains regulate the structure and function of glutamatergic synapses. Neuron 2014;84:399-415.
87. MUNAFO MR, ATTWOOD AS, FLINT J. Neuregulin 1 genotype and schizophrenia. Schizophr Bull 2008;34:9-12.
88. GONG YG, WU CN, XING QH, ZHAO XZ, ZHU J, HE L. A twomethod meta-analysis of neuregulin 1 (NRG1) association and heterogeneity in schizophrenia. Schizophr Res 2009;111:109-114.
89. MITCHELMORE C, GEDE L. Brain derived neurotrophic factor: epigenetic regulation in psychiatric disorders. Brain Res 2014;1586:162-172.
90. CHEN ZY, JING D, BATH KG et al. Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior. Science 2006;314:140-143.
91. EGAN MF, KOJIMA M, CALLICOTT JH et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003;112:257-269.
92. VAN WINKEL R, HENQUET C, ROSA A et al. Evidence that the COMT(Val158Met) polymorphism moderates sensitivity to stress in psychosis: an experience-sampling study. Am J Med Genet B Neuropsychiatr Genet 2008;147B:10-17.
93. LOPEZ-LEON S, JANSSENS AC, GONZALEZ-ZULOETA LADD AM et al. Meta-analyses of genetic studies on major depressive disorder. Mol Psychiatry 2008;13:772-785.
94. CHEN AC, MANZ N, TANG Y et al. Single-nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative trait of eventrelated potential and alcohol dependence. Alcohol Clin Exp Res 2010;34:988-996.
95. AIT-DAOUD N, SENEVIRATNE C, SMITH JB et al. Preliminary evidence for cue-induced alcohol craving modulated by serotonin transporter gene polymorphism rs1042173. Front Psychiatry 2012;3:6.
96. ZHANG X, GAINETDINOV RR, BEAULIEU JM et al. Loss-offunction mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 2005;45:11-16.