Composite Aging Markers Can Be Used for Quantitative Profiling of Aging

Gerontology

Volumn 62, Issue 1, 2015, Pages 66-68

  Shamir, Lior ^a  

^a Lawrence Technological University   (United States)

Author keywords

Aging paradigms; Biomarker; Physiological aging

Indexed keywords

AGING; ENTROPY; ENVIRONMENTAL FACTOR; FOOD CHAIN; GENETIC MARKER; HUMAN; LONGEVITY; NATURAL SELECTION; NONHUMAN; OXIDATION; PLEIOTROPY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCTIVE FITNESS; REVIEW; SENESCENCE; METABOLISM;

BIOLOGICAL MARKER;

AGING; BIOMARKERS;

EID: 84952872444     PISSN: 0304324X     EISSN: 14230003     Source Type: Journal    
DOI: 10.1159/000433466     Document Type: Review

References (12)

1. Lixie E, Edgeworth J, Shamir L: Comprehensive analysis of large sets of age-related physiological indicators reveals rapid aging around the age of 55 years. Gerontology 2015;61:526-533.
2. Carnes BA: Can any biomarker predict the temporal behavior of aging Gerontology 2015, Epub ahead of print. DOI: 10.1159/000430912.
3. Shamir L: Quantitative measurement of human aging using computer-aided radiographic texture analysis. Comput Methods Biomech Biomed Eng Imaging Vis 2013; 1: 175-183.
4. Horvath S: DNA methylation age of human tissues and cell types. Genome Biol 2013; 14:R115.
5. Budovskaya YV, Wu K, Southworth LK, Jiang M, Tedesco P, Johnson TE, Kim SK: An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C. elegans . Cell 2008; 134: 291-303.
6. Shamir L, Wolkow C, Goldberg IG: Quantitative measurement of aging using image texture entropy. Bioinformatics 2009; 25: 3060-3063.
7. Marioni R, Shah S, McRae A, Chen B, Colicino E, Harris S, Gibson J, Henders A, Redmond P, Cox S, Pattie A, Corley J, Murphy L, Martin N, Montgomery G, Feinberg A, Fallin M, Multhaup M, Jaffe A, Joehanes R, Schwartz J, Just A, Lunetta K, Murabito JM, Starr J, Horvath S, Baccarelli A, Levy D, Visscher P, Wray N, Deary I: DNA methylation age of blood predicts all-cause mortality in later life. Genome Biol 2005; 16: 25.
8. Williams GC: Pleiotropy, natural selection, and the evolution of senescence. Evolution 1957; 11: 398-411.
9. Calder WA: Size, Function, and Life History. Mineola, Courier, 1996.
10. Guerin JC: Emerging area of aging research: long-lived animals with 'negligible senescence'. Ann NY Acad Sci 2004; 1019: 518-520.
11. Kirkwood TB: Evolution of ageing. Nature 1977; 270: 301-304.
12. Carnes BA, Witten TM: How long must humans live J Gerontol A Biol Sci Med Sci 2014; 69: 965-970.