Preserving neuroplasticity: Role of glucocorticoids and neurotrophins via phosphorylation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 51, 2015, Pages 15544-15545

  McEwen, Bruce S ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; ESTROGEN RECEPTOR; GLUCOCORTICOID; MITOGEN ACTIVATED PROTEIN KINASE; NEUROTROPHIC FACTOR; NEUROTROPHIN; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 5; PROGESTERONE RECEPTOR; STEROID RECEPTOR; UNCLASSIFIED DRUG; ANTIDEPRESSANT AGENT; GLUCOCORTICOID RECEPTOR;

ACUTE STRESS; BRAIN CELL; CELL SURFACE; COGNITIVE DEFECT; GENE EXPRESSION; GENETIC TRANSCRIPTION; HIPPOCAMPUS; MENTAL DISEASE; NERVE CELL; NERVE CELL PLASTICITY; NOTE; POSITIVE FEEDBACK; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; FEMALE; MENTAL STRESS; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; ANTIDEPRESSIVE AGENTS; FEMALE; NEURONAL PLASTICITY; RECEPTORS, GLUCOCORTICOID; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL;

EID: 84952705859     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1521416112     Document Type: Note

References (25)

1. Smith MA, Makino S, Kvetnansky R, Post RM (1995) Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. J Neurosci 15(3 Pt 1):1768-1777.
2. Arango-Lievano M, et al. (2015) Neurotrophic-priming of glucocorticoid receptor signaling is essential for neuronal plasticity to stress and antidepressant treatment. Proc Natl Acad Sci USA 112:15737-15742.
3. Jeanneteau F, Garabedian MJ, Chao MV (2008) Activation of Trk neurotrophin receptors by glucocorticoids provides a neuroprotective effect. Proc Natl Acad Sci USA 105(12):4862-4867.
4. Jensen E, Jacobson H (1962) Basic guides to the mechanism of estrogen action. Recent Prog Horm Res 18:387-414.
5. Greengard P (2001) The neurobiology of slow synaptic transmission. Science 294(5544):1024-1030.
6. Mani SK, Allen JMC, Clark JH, Blaustein JD, O'Malley BW (1994) Convergent pathways for steroid hormone- and neurotransmitter-induced rat sexual behavior. Science 265(5176):1246-1249.
7. Yuen GS, McEwen BS, Akama KT (2011) LIM kinase mediates estrogen action on the actin depolymerization factor Cofilin. Brain Res 1379:44-52.
8. Akama KT, McEwen BS (2003) Estrogen stimulates postsynaptic density-95 rapid protein synthesis via the Akt/protein kinase B pathway. J Neurosci 23(6):2333-2339.
9. McEwen BS, et al. (2015) Mechanisms of stress in the brain. Nat Neurosci 18(10):1353-1363.
10. Popoli M, Yan Z, McEwen BS, Sanacora G (2012) The stressed synapse: The impact of stress and glucocorticoids on glutamate transmission. Nat Rev Neurosci 13(1):22-37.
11. Liston C, Gan WB (2011) Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo. Proc Natl Acad Sci USA 108(38):16074-16079.
12. Liston C, et al. (2013) Circadian glucocorticoid oscillations promote learning-dependent synapse formation and maintenance. Nat Neurosci 16(6):698-705.
13. Szappanos A, et al. (2015) Tissue-specific glucocorticoid signaling may determine the resistance against glucocorticoids in autoimmune diseases. Curr Med Chem 22(9):1126-1135.
14. Quan N, et al. (2003) Molecular mechanisms of glucocorticoid resistance in splenocytes of socially stressed male mice. J Neuroimmunol 137(1-2):51-58.
15. McEwen BS (2007) Physiology and neurobiology of stress and adaptation: Central role of the brain. Physiol Rev 87(3):873-904.
16. Rao RP, Anilkumar S, McEwen BS, Chattarji S (2012) Glucocorticoids protect against the delayed behavioral and cellular effects of acute stress on the amygdala. Biol Psychiatry 72(6):466-475.
17. Zohar J, et al. (2011) High dose hydrocortisone immediately after trauma may alter the trajectory of PTSD: Interplay between clinical and animal studies. Eur Neuropsychopharmacol 21(11):796-809.
18. Schelling G, Roozendaal B, De Quervain DJ-F (2004) Can posttraumatic stress disorder be prevented with glucocorticoids? Ann N Y Acad Sci 1032:158-166.
19. Dhabhar FS, Malarkey WB, Neri E, McEwen BS (2012) Stressinduced redistribution of immune cells-From barracks to boulevards to battlefields: A tale of three hormones-Curt Richter Award winner. Psychoneuroendocrinology 37(9):1345-1368.
20. McEwen BS (1998) Protective and damaging effects of stress mediators. N Engl J Med 338(3):171-179.
21. Akana SF, Jacobson L, Cascio CS, Shinsako J, Dallman MF (1988) Constant corticosterone replacement normalizes basal adrenocorticotropin (ACTH) but permits sustained ACTH hypersecretion after stress in adrenalectomized rats. Endocrinology 122(4):1337-1342.
22. Jacobson L, Akana SF, Cascio CS, Shinsako J, Dallman MF (1988) Circadian variations in plasma corticosterone permit normal termination of adrenocorticotropin responses to stress. Endocrinology 122(4):1343-1348.
23. Numakawa T, et al. (2009) Glucocorticoid receptor interaction with TrkB promotes BDNF-triggered PLC-gamma signaling for glutamate release via a glutamate transporter. Proc Natl Acad Sci USA 106(2):647-652.
24. Chen Z-Y, et al. (2006) Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior. Science 314(5796):140-143.
25. Magariños AM, et al. (2011) Effect of brain-derived neurotrophic factor haploinsufficiency on stress-induced remodeling of hippocampal neurons. Hippocampus 21(3):253-264.