Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates

American Journal of Human Genetics

Volumn 97, Issue 6, 2015, Pages 775-789

  Palamara, Pier Francesco ^a,b   Francioli, Laurent C ^c   Wilton, Peter R ^d   Genovese, Giulio ^b,e   Gusev, Alexander ^a,b   Finucane, Hilary K ^a,b,f   Sankararaman, Sriram ^b,e   Sunyaev, Shamil R ^b,g   De Bakker, Paul I W ^c   Wakeley, John ^d   Pe'Er, Itsik ^h   Price, Alkes L ^a,b  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d HARVARD UNIVERSITY   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^g BRIGHAM AND WOMEN S HOSPITAL   (United States)

^h Fu Foundation School of Engineering and Applied Science   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACKGROUND SELECTION; DEMOGRAPHY; GENE CONVERSION; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENOTYPE; HUMAN; MUTAGENIC ACTIVITY; MUTATION RATE; PEDIGREE; POINT MUTATION; POPULATION SIZE; PRIORITY JOURNAL; VALIDATION STUDY; ALLELE; BIOLOGICAL MODEL; GENETIC RECOMBINATION; GERMLINE MUTATION; HAPLOTYPE; HUMAN GENOME; INDEL MUTATION; STATISTICAL MODEL;

ALLELES; GENE FREQUENCY; GENOME, HUMAN; GERM-LINE MUTATION; HAPLOTYPES; HUMANS; INDEL MUTATION; LINEAR MODELS; MODELS, GENETIC; MUTATION RATE; RECOMBINATION, GENETIC;

EID: 84952638812     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2015.10.006     Document Type: Article

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