Olfaction in allergic rhinitis: A systematic review

Journal of Allergy and Clinical Immunology

Volumn 136, Issue 6, 2015, Pages 1460-1470

  Stuck, Boris A ^a   Hummel, Thomas ^b  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Allergy; anosmia; hyposmia; olfaction; rhinitis; smell

Indexed keywords

ALLERGEN; ANTIHISTAMINIC AGENT; AZELASTINE; BECLOMETASONE; DICLOFENAC; LEVOCETIRIZINE; LORATADINE; MOMETASONE FUROATE; NOSE SPRAY; STEROID; TRIAMCINOLONE;

ALLERGEN IMMUNOTHERAPY; ALLERGIC RHINITIS; ANOSMIA; CHRONIC BRONCHITIS; CHRONIC RHINOSINUSITIS; DISEASE ASSOCIATION; DISEASE DURATION; DISEASE SEVERITY; DRUG EFFICACY; HUMAN; HYPOSMIA; IMMUNOTHERAPY; INFLAMMATION; NOSE OBSTRUCTION; POLLEN ALLERGY; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SMELLING; SMELLING DISORDER; SUBLINGUAL IMMUNOTHERAPY; SYMPTOM; SYSTEMATIC REVIEW; THERAPY EFFECT; TREATMENT OUTCOME; ANIMAL; DRUG EFFECTS; ODOR; PATHOPHYSIOLOGY; RHINITIS, ALLERGIC;

ANIMALS; HUMANS; RHINITIS, ALLERGIC; SMELL;

EID: 84952637805     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.08.003     Document Type: Review

References (86)

1. L. Klimek, and G. Eggers Olfactory dysfunction in allergic rhinitis is related to nasal eosinophilic inflammation J Allergy Clin Immunol 100 1997 158 164
2. A.M. Seiden, A. Litwin, and D.V. Smith Olfactory deficits in allergic rhinitis Chem Senses 14 1989 746 747
3. R.L. Doty, and A. Mishra Olfaction and its alteration by nasal obstruction, rhinitis, and rhinosinusitis Laryngoscope 111 2001 409 423
4. I. Croy, S. Nordin, and T. Hummel Olfactory disorders and quality of life - an updated review Chem Senses 39 2014 185 194
5. R.J. Stevenson An initial evaluation of the functions of human olfaction Chem Senses 35 2010 3 20
6. R.L. Doty, P. Shaman, and M. Dann Development of the University of Pennsylvania Smell Identification Test: a standardized microencapsulated test of olfactory function Physiol Behav 32 1984 489 502
7. T. Hummel, B. Sekinger, S.R. Wolf, E. Pauli, and G. Kobal Sniffin' sticks': olfactory performance assessed by the combined testing of odor identification, odor discrimination and olfactory threshold Chem Senses 22 1997 39 52
8. B.N. Landis, T. Hummel, M. Hugentobler, R. Giger, and J.S. Lacroix Ratings of overall olfactory function Chem Senses 28 2003 691 694
9. M. Bende, I. Hinriksdottir, and C. Murphy Olfactory threshold in allergic rhinitis Chem Senses 20 1995 99
10. G. Eggers, and L. Klimek Der Einfluß der Hyposensibilisierungstherapie auf das Riechvermögen bei saisonaler Rhinitis allergica Allergologie 20 1997 526 527
11. J. Guilemany, A. Garcia-Pinero, I. Alobid, S. Cardelus, S. Centellas, J. Bartra, and et al. Persistent allergic rhinitis induces a moderate loss of the sense of smell Allergy 63 suppl 88 2008 72 73
12. L. Klimek, A. Glowania, B. Stuck, K. Hörmann, and O. Pfaar Olfactory function in seasonal allergic rhinitis can be improved by allergen-specific immunotherapy Allergy 66 suppl 94 2011 632
13. J.M. Pinto, S. Jeswani, L. Reder, J. Wang, R. Perez, M. DeTineo, and et al. Olfactory cleft inflammation is present in seasonal allergic rhinitis and improves with intranasal steroids J Allergy Clin Immunol 121 suppl 2008 S277
14. M. Shariat, M. Moin, Z. Pourpak, L. Sharifi, M. Khalesi, M. Movahedi, and et al. The smell dysfunction in allergic rhinitis and its impacts on quality of life Allergy 67 suppl 96 2012 492 493
15. E. Tsakiropoulou, I. Konstantinidis, and J. Constantinidis Allergic rhinitis as a risk factor of olfactory dysfunction: outcome from a smell and taste clinic Allergy 66 suppl 94 2011 353
16. J.P. Haguenauer Controlled study of sodium cromoglycate and beclomethasone dipropionate in the local treatment of chronic aperiodic rhinitis Revue Francaise d'Allergologie et d'Immunologie Clinique 21 1981 167 169
17. A. Baccioglu Kavut, and F. Kalpaklioglu Efficacy and safety of once daily triamcinolone acetonide aqueous nasal spray in adults with non-allergic and allergic rhinitis Allergol Immunopathol (Madr) 41 2013 374 380
18. H.C. Lin, P.W. Lin, M. Friedman, H.W. Chang, Y.Y. Su, Y.J. Chen, and et al. Long-term results of radiofrequency turbinoplasty for allergic rhinitis refractory to medical therapy Arch Otolaryngol Head Neck Surg 136 2010 892 895
19. S.A. Said, M.D. McHembe, P.L. Chalya, P. Rambau, and J.M. Gilyoma Allergic rhinitis and its associated co-morbidities at Bugando Medical Centre in Northwestern Tanzania; a prospective review of 190 cases BMC Ear Nose Throat Disord 12 2012 13
20. S. Yonekura, Y. Okamoto, D. Sakurai, S. Horiguchi, T. Hanazawa, A. Nakano, and et al. Sublingual immunotherapy with house dust extract for house dust-mite allergic rhinitis in children Allergol Int 59 2010 381 388
21. M.S. Benninger Rhinitis, sinusitis, and their relationships to allergies Am J Rhinol 6 1992 37 43
22. R.I. Henkin, M. Schultz, and L. Minnick-Poppe Intranasal theophylline treatment of hyposmia and hypogeusia: a pilot study Arch Otolaryngol Head Neck Surg 138 2012 1064 1070
23. C. Incandela, G. Calamusa, M.F. Massenti, S. Incandela, R. Speciale, and E. Amodio Long-term efficacy of radiofrequency treatment of turbinate hypertrophy: a patient based point of view Indian J Otolaryngol Head Neck Surg 65 suppl 2 2013 226 230
24. M. Katotomichelakis, E. Simopoulos, N. Zhang, G. Tripsianis, G. Danielides, and M. Livaditis Olfactory dysfunction and asthma as risk factors for poor quality of life in upper airway diseases Am J Rhinol Allergy 27 2013 293 298
25. B.S. Paparo, O. Leri, P. Andreoli, A. Arcai Chirra, M. Casagrande, M.A. Addessi, and et al. Allergic rhinitis, olfactory disorders and secretory IgA Riv Eur Sci Med Farmacol 18 1996 157 161
26. M. Simola, and H. Malmberg Sense of smell in allergic and nonallergic rhinitis Allergy 53 1998 190 194
27. O. Hilberg Effect of terfenadine and budesonide on nasal symptoms, olfaction, and nasal airway patency following allergen challenge Allergy 50 1995 683 688
28. I. Hinriksdottir, C. Murphy, and M. Bende "Olfactory threshold after nasal allergen challenge" ORL J Otorhinolaryngol Relat Spec 59 1 1997 36 38
29. I. Catana, M. Chirila, R. Bologa, I. Crisan, S. Negoias, and M. Cosgarea Hyposmia in persistent allergic rhinitis: effects of topical therapy with mometasone furoate and fluticasone furoate Allergy 65 suppl 92 2010 719 720
30. C. Bachert, W. Darlath, and B. Janzen Triamcinolonacetonid-Nasenspray (Nasacort®) bei der Behandlung der saisonalen und perennialen allergischen Rhinitis Allergologie 21 suppl 1998 S17 S26
31. M. Blaiss Current concepts and therapeutic strategies for allergic rhinitis in school-age children Clin Ther 26 2004 1876 1889
32. L. Borish The role of leukotrienes in upper and lower airway inflammation and the implications for treatment Ann Allergy Asthma Immunol 88 suppl 1 2002 16 22
33. G.C. Passali, M. Ralli, J. Galli, L. Calò, and G. Paludetti How relevant is the impairment of smell for the quality of life in allergic rhinitis? Curr Opin Allergy Clin Immunol 8 2008 238 242
34. L. Klimek, and G. Eggers Untersuchungen zum Riechvermögen bei Graspollenallergikern Allergologie 19 1996 382 386
35. A.J. Apter, A.E. Mott, W.S. Cain, J.D. Spiro, and M.C. Barwick Olfactory loss and allergic rhinitis J Allergy Clin Immunol 90 1992 670 680
36. R.M. Ashequr, and C. Kamei Electroencephalogram and behavioral changes induced by histamine application into the nasal cavity and the effects of some H-1-receptor antagonists Int Immunopharmacol 5 2005 1741 1748
37. B.T. Fein, P.B. Kamin, and N.N. Fein The loss of sense of smell in nasal allergy Ann Allergy 24 1966 278 283
38. R.I. Henkin, L.M. Levy, and A. Fordyce Taste and smell function in chronic disease: a review of clinical and biochemical evaluations of taste and smell dysfunction in over 5000 patients at The Taste and Smell Clinic in Washington, DC Am J Otolaryngol 34 2013 477 489
39. P.K. Keith, M. Desrosiers, T. Laister, R.R. Schellenberg, and S. Waserman The burden of allergic rhinitis (AR) in Canada: perspectives of physicians and patients Allergy Asthma Clin Immunol 8 2012 7
40. A.P. Lane, B. Zweiman, D.C. Lanza, D. Swift, R. Doty, H.J. Dhong, and et al. Acoustic rhinometry in the study of the acute nasal allergic response Ann Otol Rhinol Laryngol 105 1996 811 818
41. E.O. Meltzer, M.S. Blaiss, R.M. Naclerio, S.W. Stoloff, M.J. Derebery, H.S. Nelson, and et al. Burden of allergic rhinitis: allergies in America, Latin America, and Asia-Pacific adult surveys Allergy Asthma Proc 33 suppl 1 2012 S113 S141
42. B. Zweiman, J. Getsy, M. Kalenian, A. Lane, L.B. Schwartz, R. Doty, and et al. Nasal airway changes assessed by acoustic rhinometry and mediator release during immediate and late reactions to allergen challenge J Allergy Clin Immunol 100 1997 624 631
43. P.W. Hellings, and P. Rombaux Medical therapy and smell dysfunction B-ENT 5 suppl 13 2009 71 75
44. H.M. Druce Olfaction and rhinitis Ann Allergy Asthma Immunol 75 1995 291 293
45. A. Cardesín, I. Alobid, P. Benítez, E. Sierra, J. de Haro, M. Bernal-Sprekelsen, and et al. Barcelona Smell Test-24 (BAST-24): validation and smell characteristics in the healthy Spanish population Rhinology 44 2006 83 89
46. W.S. Cain, J. Gent, F.A. Catalanotto, and R.B. Goodspeed Clinical evaluation of olfaction Am J Otolaryngol 4 1983 252 256
47. G. Kobal, L. Klimek, M. Wolfensberger, H. Gudziol, A. Temmel, C.M. Owen, and et al. Multicenter investigation of 1,036 subjects using a standardized method for the assessment of olfactory function combining tests of odor identification, odor discrimination, and olfactory thresholds Eur Arch Otorhinolaryngol 257 2000 205 211
48. B.J. Cowart, K. Flynn-Rodden, S.J. McGeady, and L.D. Lowry Hyposmia in allergic rhinitis J Allergy Clin Immunol 91 1993 747 751
49. E. Binder, E. Holopainen, H. Malmberg, and O. Salo Anamnestic data in allergic rhinitis Allergy 37 1982 389 396
50. E.O. Meltzer, A.A. Jalowayski, H.A. Orgel, and A.G. Harris Subjective and objective assessments in patients with seasonal allergic rhinitis: effects of therapy with mometasone furoate nasal spray J Allergy Clin Immunol 102 1998 39 49
51. S. Chaiyasate, K. Roongrotwattanasiri, S. Fooanant, and Y. Sumitsawan Key nasal symptoms predicting a positive skin test in allergic rhinitis and patient characteristics according to ARIA classification J Med Assoc Thai 92 2009 377 381
52. G. Di Lorenzo, M.L. Pacor, E. Amodio, M.S. Leto-Barone, S. La Piana, A. D'Alcamo, and et al. Differences and similarities between allergic and nonallergic rhinitis in a large sample of adult patients with rhinitis symptoms Int Arch Allergy Immunol 155 2011 263 270
53. P. Jareoncharsri, V. Thitadilok, C. Bunnag, K. Ungkanont, S. Voraprayoon, and P. Tansuriyawong Nasal endoscopic findings in patients with perennial allergic rhinitis Asian Pac J Allergy Immunol 17 1999 261 267
54. J. Guss, L. Doghramji, C. Reger, and A.G. Chiu Olfactory dysfunction in allergic rhinitis ORL J Otorhinolaryngol Relat Spec 71 2009 268 272
55. A. Sivam, S. Jeswani, L. Reder, J. Wang, M. DeTineo, J. Taxy, and et al. Olfactory cleft inflammation is present in seasonal allergic rhinitis and is reduced with intranasal steroids Am J Rhinol Allergy 24 2010 286 290
56. J.M. Guilemany, A. García-Piñero, I. Alobid, S. Cardelús, S. Centellas, J. Bartra, and et al. Persistent allergic rhinitis has a moderate impact on the sense of smell, depending on both nasal congestion and inflammation Laryngoscope 119 2009 233 238
57. S. Becker, C. Pflugbeil, M. Gröger, M. Canis, G.J. Ledderose, and M.F. Kramer Olfactory dysfunction in seasonal and perennial allergic rhinitis Acta Otolaryngol 132 2012 763 768
58. P. Olsson, N. Berglind, T. Bellander, and P. Stjärne Prevalence of self-reported allergic and non-allergic rhinitis symptoms in Stockholm: relation to age, gender, olfactory sense and smoking Acta Otolaryngol 123 2003 75 80
59. S.S. Mann, S. Maini, K.S. Nageswari, H. Mohan, and A. Handa Assessment of olfactory status in allergic and non-allergic rhinitis patients Indian J Physiol Pharmacol 46 2002 186 194
60. A.J. Apter, A.E. Mott, M.E. Frank, and J.M. Clive Allergic rhinitis and olfactory loss Ann Allergy Asthma Immunol 75 1995 311 316
61. A.J. Apter, J.F. Gent, and M.E. Frank Fluctuating olfactory sensitivity and distorted odor perception in allergic rhinitis Arch Otolaryngol Head Neck Surg 125 1999 1005 1010
62. C.S. Rhee, J.H. Wee, J.C. Ahn, W.H. Lee, K.L. Tan, S. Ahn, and et al. Prevalence, risk factors and comorbidities of allergic rhinitis in South Korea: the Fifth Korea National Health and Nutrition Examination Survey Am J Rhinol Allergy 28 2014 e107 e114
63. C. Bachert, P. van Cauwenberge, N. Khaltaev World Health Organization Allergic rhinitis and its impact on asthma. In collaboration with the World Health Organization. Executive summary of the workshop report. 7-10 December 1999, Geneva, Switzerland Allergy 57 2002 841 855
64. B. Moll, L. Klimek, G. Eggers, and W. Mann Comparison of olfactory function in patients with seasonal and perennial allergic rhinitis Allergy 53 1998 297 301
65. L. Klimek Das Riechvermögen bei allergischer Rhinitis Pneumologie 52 1998 196 202
66. B. Rydzewski, A. Pruszewicz, and W.J. Sulkowski Assessment of smell and taste in patients with allergic rhinitis Acta Otolaryngol 120 2000 323 326
67. P. Khanna, and A. Shah Categorization of patients with allergic rhinitis: a comparative profile of "sneezers and runners" and "blockers" Ann Allergy Asthma Immunol 94 2005 60 64
68. C.A. Elsberg, and J. Levy A new and simple method of quantitative olfactometry Bull Neurol Inst N Y 4 1953 5 19
69. W.H. Lee, J.H. Wee, D.K. Kim, C.S. Rhee, C.H. Lee, S. Ahn, and et al. Prevalence of subjective olfactory dysfunction and its risk factors: Korean National Health and Nutrition Examination Survey PLoS One 8 2013 e62725
70. W. Wober, C.D. Diez Crespo, and M. Bähre Evaluation of the drug monitoring programme of azelastine hydrochloride nasal spray in the treatment of allergic rhinitis in children under 13 years of age Arzneimittelforschung 47 1997 841 844
71. J.M. Guilemany, A. García-Piñero, I. Alobid, S. Centellas, F.S. Mariño, A. Valero, and et al. The loss of smell in persistent allergic rhinitis is improved by levocetirizine due to reduction of nasal inflammation but not nasal congestion (the CIRANO study) Int Arch Allergy Immunol 158 2012 184 190
72. R. Gambardella A comparison of the efficacy of azelastine nasal spray and loratidine tablets in the treatment of seasonal allergic rhinitis J Int Med Res 21 1993 268 275
73. A.F. Kalpaklioglu, and A.B. Kavut Comparison of azelastine versus triamcinolone nasal spray in allergic and nonallergic rhinitis Am J Rhinol Allergy 24 2010 29 33
74. D.G. Golding-Wood, M. Holmstrom, Y. Darby, G.K. Scadding, and V.J. Lund The treatment of hyposmia with intranasal steroids J Laryngol Otol 110 1996 132 135
75. B.A. Stuck, A. Blum, A.E. Hagner, T. Hummel, L. Klimek, and K. Hörmann Mometasone furoate nasal spray improves olfactory performance in seasonal allergic rhinitis Allergy 58 2003 1195
76. T. Higaki, M. Okano, S. Makihara, T. Fujiwara, T. Haruna, Y. Noda, and et al. Early interventional treatment with intranasal corticosteroids compared with postonset treatment in pollinosis Ann Allergy Asthma Immunol 109 2012 458 464
77. M.J. Radcliffe, F.C. Lampe, and J. Brostoff Allergen-specific low-dose immunotherapy in perennial allergic rhinitis: a double-blind placebo-controlled crossover study J Investig Allergol Clin Immunol 6 1996 242 247
78. H. Chang, D.H. Han, J.H. Mo, J.W. Kim, D.Y. Kim, C.H. Lee, and et al. Early compliance and efficacy of sublingual immunotherapy in patients with allergic rhinitis for house dust mites Clin Exp Otorhinolaryngol 2 2009 136 140
79. S.J. Mun, J.M. Shin, D.H. Han, J.W. Kim, D.Y. Kim, C.H. Lee, and et al. Efficacy and safety of a once-daily sublingual immunotherapy without escalation regimen in house dust mite induced allergic rhinitis Int Forum Allergy Rhinol 3 2013 177 183
80. M. Katotomichelakis, E. Simopoulos, G. Tripsianis, E. Prokopakis, G. Danielides, S.G. Velegrakis, and et al. Improvement of olfactory function for quality of life recovery Laryngoscope 123 2013 E10 E16
81. D. Tansuker, B.U. Coşkun, Y.O. Uçal, E. Sözen, C. Erdurak, E. Sakalli, and et al. Effects of systemic immunotherapy on olfactory function in allergic rhinitis patients J Craniofac Surg 25 2014 e339 e343
82. K. Ikeda, T. Oshima, M. Suzuki, H. Suzuki, and A. Shimomura Functional inferior turbinosurgery (FITS) for the treatment of resistant chronic rhinitis Acta Otolaryngol 126 2006 739 745
83. P.K. Parida, K. Santhosh, S. Ganesan, G. Surianarayanan, and S.K. Saxena The efficacy of radiofrequency volumetric tissue reduction of hypertrophied inferior turbinate in allergic rhinitis Indian J Med Sci 65 2011 269 277
84. W.C. Lee, D.W. Morgan, and J.F. Marriott Are prostaglandins major mediators in perennial allergic rhinitis? Rhinology 34 1996 130 135
85. K.H. Hu, and W.T. Li Clinical effects of far-infrared therapy in patients with allergic rhinitis Conf Proc IEEE Eng Med Biol Soc 2007 2007 1479 1482
86. O. Hilberg Objective measurement of nasal airway dimensions using acoustic rhinometry: methodological and clinical aspects Allergy 57 suppl 70 2002 5 39