Characterization of a novel integrin binding protein, vps33b, which is important for platelet activation and in vivo thrombosis and hemostasis

Circulation

Volumn 132, Issue 24, 2015, Pages 2334-2344

  Xiang, Binggang ^a   Zhang, Guoying ^b   Ye, Shaojing ^a   Zhang, Rui ^a   Huang, Cai ^b   Liu, Jun ^c   Tao, Min ^d   Ruan, Changgeng ^e   Smyth, Susan S ^e   Whiteheart, Sidney W ^d   Li, Zhenyu ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b MAYO CLINIC   (United States)

^c Department of Hematology ^*  (United States)

^d SOOCHOW UNIVERSITY   (China)

^e LEXINGTON VA MEDICAL CENTER   (United States)

Author keywords

blood platelets; hemostasis; integrins; platelet aggregation; signal transduction; thrombosis; VPS33B protein, mouse

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA INTEGRIN; BETA3 INTEGRIN; FIBRINOGEN; INTEGRIN; INTEGRIN ALPHA2B BETA3; MUNC18 PROTEIN; MYOSIN LIGHT CHAIN; PADGEM PROTEIN; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; VPS33B PROTEIN; CARRIER PROTEIN; VESICULAR TRANSPORT PROTEIN; VPS33B PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOGENESIS; BLEEDING TIME; BLOOD CLOT RETRACTION; CELL SPREADING; CHO CELL LINE; CONTROLLED STUDY; ENDOCYTOSIS; EXON; EXTRACELLULAR SPACE; FEMALE; HEMOSTASIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MEGAKARYOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; THROMBOCYTE RELEASE REACTION; THROMBOSIS; ANIMAL; BIOSYNTHESIS; CRICETULUS; HAMSTER; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT;

ANIMALS; CARRIER PROTEINS; CHO CELLS; CRICETINAE; CRICETULUS; HEMOSTASIS; INTEGRINS; MICE; MICE, KNOCKOUT; PLATELET ACTIVATION; PROTEIN TRANSPORT; THROMBOSIS; VESICULAR TRANSPORT PROTEINS;

EID: 84952628597     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.115.018361     Document Type: Article

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