Soft Discoidal Polymeric Nanoconstructs Resist Macrophage Uptake and Enhance Vascular Targeting in Tumors

ACS Nano

Volumn 9, Issue 12, 2015, Pages 11628-11641

  Key, Jaehong ^a,b   Palange, Anna Lisa ^a,d   Gentile, Francesco ^d   Aryal, Santosh ^a,e   Stigliano, Cinzia ^a   Di Mascolo, Daniele ^d   De Rosa, Enrica ^a   Cho, Minjung ^a   Lee, Yeonju ^a   Singh, Jaykrishna ^a   Decuzzi, Paolo ^a,c,d  

^a HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^b Yonsei University Wonju   (South Korea)

^c UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^d ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^e KANSAS STATE UNIVERSITY   (United States)

Author keywords

iron oxide nanocubes; macrophage uptake; nanoparticle shape; nanoparticle stiffness; tumor imaging

Indexed keywords

DISEASES; ELECTROSTATICS; GEOMETRY; MACROPHAGES; MEDICAL APPLICATIONS; NANOPARTICLES; STIFFNESS; TUMORS;

BIOMEDICAL APPLICATIONS; CIRCULATION HALF-LIFES; HYDROPHOBIC AND HYDROPHILIC; MONONUCLEAR PHAGOCYTE SYSTEMS; NANOCUBES; NANOPARTICLE SHAPE; SURFACE ELECTROSTATICS; TUMOR IMAGING;

POLYMERS;

ANTINEOPLASTIC AGENT; FERRIC ION; FERRIC OXIDE; NANOPARTICLE; POLYMER;

ANIMAL; CHEMISTRY; EXPERIMENTAL NEOPLASM; FEMALE; HUMAN; MACROPHAGE; METABOLISM; MOLECULAR IMAGING; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NUDE MOUSE; PATHOLOGY; PROCEDURES; TRANSGENIC MOUSE; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; FEMALE; FERRIC COMPOUNDS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MACROPHAGES; MICE; MICE, NUDE; MICE, TRANSGENIC; MOLECULAR IMAGING; NANOPARTICLES; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; POLYMERS;

EID: 84952362031     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b04866     Document Type: Article

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