Local Anesthetic Systemic Toxicity (LAST): Not Gone, Hopefully Not Forgotten

Regional Anesthesia and Pain Medicine

Volumn 41, Issue 1, 2016, Pages 1-2

  Weinberg, Guy ^a   Barron, Greg ^b  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b Lax Sebenius LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; ETIDOCAINE; LOCAL ANESTHETIC AGENT;

CAUDAL ANESTHESIA; CLINICAL PRACTICE; DRUG TOXICITY; EDITORIAL; EPIDURAL ANESTHESIA; HEART ARREST; HUMAN; LOCAL ANESTHETIC SYSTEMIC TOXICITY; NERVE BLOCK; PATIENT SAFETY; PRIORITY JOURNAL; REGIONAL ANESTHESIA; LOCAL ANESTHESIA;

ANESTHESIA, LOCAL; ANESTHETICS, LOCAL; HUMANS;

EID: 84952324518     PISSN: 10987339     EISSN: 15328651     Source Type: Journal    
DOI: 10.1097/AAP.0000000000000334     Document Type: Editorial

References (14)

1. Liu SS, Ortolan S, Sandoval MV, et al. Cardiac arrest and seizures due to local anesthetic systemic toxicity after peripheral nerve blocks: should we still fear the reaper? Reg Anesth Pain Med. 2016;41:5-21.
2. Mulroy MF. Systemic toxicity and cardiotoxicity from local anesthetics: incidence and preventive measures. Reg Anesth Pain Med. 2002;27: 556-561.
3. Auroy Y, Benhamou D, Bargues L, et al. Major complications of regional anesthesia in France: the SOS Regional Anesthesia Hotline Service. Anesthesiology. 2002;97:1274-1280.
4. Heinonen JA, Litonius E, Pitkänen M, Rosenberg PH. Incidence of severe local anaesthetic toxicity and adoption of lipid rescue in Finnish anaesthesia departments in 2011-2013. Acta Anaesthesiol Scand. 2015;59:1032-1037.
5. Orebaugh SL, Kentor ML, Williams BA. Adverse outcomes associated with nerve stimulator-guided and ultrasound-guided peripheral nerve blocks by supervised trainees: update of a single-site database. Reg Anesth Pain Med. 2012;37:577-582.
6. Sites BD, Taenzer AH, Herrick MD, et al. Incidence of local anesthetic systemic toxicity and postoperative neurologic symptoms associated with 12,668 ultrasound-guided nerve blocks: an analysis from a prospective clinical registry. Reg Anesth Pain Med. 2012;37:478-482.
7. Barrington MJ,Kluger R. Ultrasound guidance reduces the risk of local anesthetic systemic toxicity following peripheral nerve blockade Reg Anesth Pain Med. 2013 38 289-297
8. Barron G, Leider S, Stack J. The effect of safe experience on a warnings' impact: sex, drugs, and rock-n-roll. Organ Behav Hum Dec. 2008;106: 125-142.
9. Hertwig R, Barron G, Weber EU, Erev I. Decisions from experience and the effect of rare events in risky choice. Psychol Sci. 2004;15:534-539.
10. Royce RA, Seña A, Cates W Jr., Cohen MS. Sexual transmission of HIV. N Engl JMed. 1997;336:1072-1078.
11. Tobin R. Recalls and the remediation of hazardous or defective consumer products: the experienc es of the consumer product safety commission and the national highway traffic safety administration. J Consumer Affairs. 1982;16:278-306.
12. Frost JJ, Forrest JD. Understanding the impact of effective teenage pregnancy prevention programs. Fam Plann Perspect. 1995;27:188-195.
13. Moore DC, Bridenbaugh LD. Oxygen: The antidote for systemic toxic reactions from local anesthetic drugs. JAMA. 1960;174:102-107.
14. Albright GA. Cardiac arrest following regional anesthesia with etidocaine or bupivacaine. Anesthesiology. 1979;51:285-287.