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Volumn 127, Issue 23-24, 2015, Pages 907-919

Iron metabolism and iron supplementation in cancer patients

(17)  Ludwig, Heinz a   Evstatiev, Rayko b   Kornek, Gabriela b   Aapro, Matti c   Bauernhofer, Thomas d   Buxhofer Ausch, Veronika e   Fridrik, Michael f   Geissler, Dietmar g   Geissler, Klaus h   Gisslinger, Heinz b   Koller, Elisabeth i   Kopetzky, Gerhard j   Lang, Alois k   Rumpold, Holger l   Steurer, Michael d   Kamali, Houman m   Link, Hartmut n  


Author keywords

Functional and absolute iron deficiency; Iron deficiency; Iron supplementation; Recommendations for clinical practice; Tumor anemia

Indexed keywords

ANTIANEMIC AGENT; FERRITIN; FERROPORTIN; FERROUS ION; HEPCIDIN; IRON; TRANSFERRIN RECEPTOR;

EID: 84951908324     PISSN: 00435325     EISSN: 16137671     Source Type: Journal    
DOI: 10.1007/s00508-015-0842-3     Document Type: Review
Times cited : (103)

References (72)
  • 1
    • 0032964289 scopus 로고    scopus 로고
    • Cellular iron metabolism
    • Ponka P. Cellular iron metabolism. Kidney Int. 1999;55:2–11.
    • (1999) Kidney Int , vol.55 , pp. 2-11
    • Ponka, P.1
  • 2
    • 84883788244 scopus 로고    scopus 로고
    • Prevalence of iron deficiency across different tumors and its association with poor performance status, disease status and anemia
    • Ludwig H, Müldür E, Endler G, et al. Prevalence of iron deficiency across different tumors and its association with poor performance status, disease status and anemia. Ann Oncol. 2013;24:1886–92.
    • (2013) Ann Oncol , vol.24 , pp. 1886-1892
    • Ludwig, H.1    Müldür, E.2    Endler, G.3
  • 3
    • 72449156527 scopus 로고    scopus 로고
    • Ferric carboxymaltose in patients with heart failure and iron deficiency
    • Anker SD, Comin Colet J, Filippatos G, et al. Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med. 2009;361:2436–48.
    • (2009) N Engl J Med , vol.361 , pp. 2436-2448
    • Anker, S.D.1    Comin Colet, J.2    Filippatos, G.3
  • 4
    • 84872210114 scopus 로고    scopus 로고
    • High prevalence of iron deficiency across different tumors correlates with anemia, increases during cancer treatment and is associated with poor performance status
    • Ludwig H, Müldür E, Endler G, et al. High prevalence of iron deficiency across different tumors correlates with anemia, increases during cancer treatment and is associated with poor performance status. Haematologica. 2011;96(Suppl 2):409.
    • (2011) Haematologica , vol.96 , pp. 409
    • Ludwig, H.1    Müldür, E.2    Endler, G.3
  • 5
    • 0030976067 scopus 로고    scopus 로고
    • Prevalence of iron deficiency in the United States
    • Looker AC, Dallman PR, Carroll MD, et al. Prevalence of iron deficiency in the United States. JAMA. 1997;277:973–6.
    • (1997) JAMA , vol.277 , pp. 973-976
    • Looker, A.C.1    Dallman, P.R.2    Carroll, M.D.3
  • 6
    • 5344263788 scopus 로고    scopus 로고
    • The European Cancer Anaemia Survey (ECAS): a large, multinational, prospective survey defining the prevalence, incidence, and treatment of anaemia in cancer patients
    • Ludwig H, Van Belle S, Barrett-Lee P, et al. The European Cancer Anaemia Survey (ECAS): a large, multinational, prospective survey defining the prevalence, incidence, and treatment of anaemia in cancer patients. Eur J Cancer. 2004;40:2293–306.
    • (2004) Eur J Cancer , vol.40 , pp. 2293-2306
    • Ludwig, H.1    Van Belle, S.2    Barrett-Lee, P.3
  • 7
    • 3142751987 scopus 로고    scopus 로고
    • Prevalence and management of anaemia in haematologic cancer patients receiving cyclic nonplatinum chemotherapy: results of a prospective national chart survey
    • Steurer M, Wagner H, Gastl G. Prevalence and management of anaemia in haematologic cancer patients receiving cyclic nonplatinum chemotherapy: results of a prospective national chart survey. Wien Klin Wochenschr. 2004;116:367–72.
    • (2004) Wien Klin Wochenschr , vol.116 , pp. 367-372
    • Steurer, M.1    Wagner, H.2    Gastl, G.3
  • 8
    • 21244442321 scopus 로고    scopus 로고
    • The prevalence of iron deficiency among patients presenting with colorectal cancer
    • Beale AL, Penney MD, Allison MC. The prevalence of iron deficiency among patients presenting with colorectal cancer. Colorectal Dis. 2005;7:398–402.
    • (2005) Colorectal Dis , vol.7 , pp. 398-402
    • Beale, A.L.1    Penney, M.D.2    Allison, M.C.3
  • 9
    • 2342439434 scopus 로고    scopus 로고
    • Serum ferritin levels and transferrin saturation in men with prostate cancer
    • Kuvibidila SR, Gauthier T, Rayford W. Serum ferritin levels and transferrin saturation in men with prostate cancer. J Natl Med Assoc. 2004;96:641–9.
    • (2004) J Natl Med Assoc , vol.96 , pp. 641-649
    • Kuvibidila, S.R.1    Gauthier, T.2    Rayford, W.3
  • 10
    • 78651469284 scopus 로고    scopus 로고
    • A new concept for the differential diagnosis and therapy of anaemia in cancer patients
    • Steinmetz HT, Tsamaloukas A, Schmitz S, et al. A new concept for the differential diagnosis and therapy of anaemia in cancer patients. Support Care Cancer. 2010;19:261–9.
    • (2010) Support Care Cancer , vol.19 , pp. 261-269
    • Steinmetz, H.T.1    Tsamaloukas, A.2    Schmitz, S.3
  • 11
    • 84864912800 scopus 로고    scopus 로고
    • A prospective observational study exploring the impact of iron status on response to darbepoetin alfa in patients with chemotherapy induced anemia
    • Beguin Y, Lybaert W, Bosly A. A prospective observational study exploring the impact of iron status on response to darbepoetin alfa in patients with chemotherapy induced anemia. Blood. 2009;114:2007.
    • (2009) Blood , vol.114 , pp. 2007
    • Beguin, Y.1    Lybaert, W.2    Bosly, A.3
  • 12
    • 0035875880 scopus 로고    scopus 로고
    • Anemia as an independent prognostic factor for survival in patients with cancer: a systemic, quantitative review
    • Caro JJ, Salas M, Ward A, et al. Anemia as an independent prognostic factor for survival in patients with cancer: a systemic, quantitative review. Cancer. 2001;91:2214–21.
    • (2001) Cancer , vol.91 , pp. 2214-2221
    • Caro, J.J.1    Salas, M.2    Ward, A.3
  • 13
    • 0037102975 scopus 로고    scopus 로고
    • Relationship between changes in hemoglobin level and quality of life during chemotherapy in anemic cancer patients receiving epoetin alfa therapy
    • Crawford J, Cella D, Cleeland CS, et al. Relationship between changes in hemoglobin level and quality of life during chemotherapy in anemic cancer patients receiving epoetin alfa therapy. Cancer. 2002;95:888–95.
    • (2002) Cancer , vol.95 , pp. 888-895
    • Crawford, J.1    Cella, D.2    Cleeland, C.S.3
  • 14
    • 66149150585 scopus 로고    scopus 로고
    • Physiologische Bedeutung von Eisen. Essenziell und toxisch
    • Hahn A. Physiologische Bedeutung von Eisen. Essenziell und toxisch. Pharm Unserer Zeit. 2009;38:232–9.
    • (2009) Pharm Unserer Zeit , vol.38 , pp. 232-239
    • Hahn, A.1
  • 15
    • 84860574815 scopus 로고    scopus 로고
    • Iron sensing and signalling
    • Evstatiev R, Gasche C. Iron sensing and signalling. Gut. 2012;61:933–52.
    • (2012) Gut , vol.61 , pp. 933-952
    • Evstatiev, R.1    Gasche, C.2
  • 16
    • 77954249308 scopus 로고    scopus 로고
    • Two to tango: regulation of mammalian iron metabolism
    • Hentze MW, Muckenthaler MU, Galy B, et al. Two to tango: regulation of mammalian iron metabolism. Cell. 2010;142:24–38.
    • (2010) Cell , vol.142 , pp. 24-38
    • Hentze, M.W.1    Muckenthaler, M.U.2    Galy, B.3
  • 17
    • 78649753411 scopus 로고    scopus 로고
    • Detection, evaluation, and management of iron-restricted erythropoiesis
    • Goodnough LT, Nemeth E, Ganz T. Detection, evaluation, and management of iron-restricted erythropoiesis. Blood. 2010;116:4754–61.
    • (2010) Blood , vol.116 , pp. 4754-4761
    • Goodnough, L.T.1    Nemeth, E.2    Ganz, T.3
  • 18
    • 84903578007 scopus 로고    scopus 로고
    • Identification of erythroferrone as an erythroid regulator of iron metabolism
    • Kautz L, Jung G, Valore EV, et al. Identification of erythroferrone as an erythroid regulator of iron metabolism. Nat Genet. 2014;46:678–84.
    • (2014) Nat Genet , vol.46 , pp. 678-684
    • Kautz, L.1    Jung, G.2    Valore, E.V.3
  • 19
    • 14744278436 scopus 로고    scopus 로고
    • Anemia of chronic disease
    • Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med. 2005;352:1011–23.
    • (2005) N Engl J Med , vol.352 , pp. 1011-1023
    • Weiss, G.1    Goodnough, L.T.2
  • 20
    • 42949127743 scopus 로고    scopus 로고
    • Anaemia of cancer: an overview of mechanisms involved in its pathogenesis
    • Grotto HZ. Anaemia of cancer: an overview of mechanisms involved in its pathogenesis. Med Oncol. 2008;25:12–21.
    • (2008) Med Oncol , vol.25 , pp. 12-21
    • Grotto, H.Z.1
  • 21
    • 0037103231 scopus 로고    scopus 로고
    • Role of IL-10 for induction of anemia during inflammation
    • Tilg H, Ulmer H, Kaser A, et al. Role of IL-10 for induction of anemia during inflammation. J Immunol. 2002;169:2204–9.
    • (2002) J Immunol , vol.169 , pp. 2204-2209
    • Tilg, H.1    Ulmer, H.2    Kaser, A.3
  • 22
    • 33846702712 scopus 로고    scopus 로고
    • Assessing iron status: beyond serum ferritin and transferrin saturation
    • Wish JB. Assessing iron status: beyond serum ferritin and transferrin saturation. Clin J Am Soc Nephrol. 2006;1(Suppl 1):4–8.
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 4-8
    • Wish, J.B.1
  • 23
    • 0036854276 scopus 로고    scopus 로고
    • Prediction of response and other improvements on the limitations of recombinant human erythropoietin therapy in anemic cancer patients
    • Beguin Y. Prediction of response and other improvements on the limitations of recombinant human erythropoietin therapy in anemic cancer patients. Haematologica. 2002;87:1209–21.
    • (2002) Haematologica , vol.87 , pp. 1209-1221
    • Beguin, Y.1
  • 24
    • 84882790318 scopus 로고    scopus 로고
    • The significance of ferritin in cancer: anti-oxidation, inflammation and tumorigenesis
    • Alkhateeb AA, Connor JR. The significance of ferritin in cancer: anti-oxidation, inflammation and tumorigenesis. Biochim Biophys Acta. 2013;1836:245–54.
    • (2013) Biochim Biophys Acta , vol.1836 , pp. 245-254
    • Alkhateeb, A.A.1    Connor, J.R.2
  • 25
    • 84864955819 scopus 로고    scopus 로고
    • Prevalence and management of cancer-related anaemia, iron deficiency and the specific role of i.v. iron
    • Aapro M, Osterborg A, Gascon P, et al. Prevalence and management of cancer-related anaemia, iron deficiency and the specific role of i.v. iron. Ann Oncol. 2012;23:1954–62.
    • (2012) Ann Oncol , vol.23 , pp. 1954-1962
    • Aapro, M.1    Osterborg, A.2    Gascon, P.3
  • 26
    • 33947405774 scopus 로고    scopus 로고
    • Addition of intravenous iron to epoetin beta increases hemoglobin response and decreases epoetin dose requirement in anemic patients with lymphoproliferative malignancies: a randomized multicenter study
    • Hedenus M, Birgegard G, Nasman P, et al. Addition of intravenous iron to epoetin beta increases hemoglobin response and decreases epoetin dose requirement in anemic patients with lymphoproliferative malignancies: a randomized multicenter study. Leukemia. 2007;21:627–32.
    • (2007) Leukemia , vol.21 , pp. 627-632
    • Hedenus, M.1    Birgegard, G.2    Nasman, P.3
  • 27
    • 78649242240 scopus 로고    scopus 로고
    • High prevalence of iron deficiency in patients with various hematological and malignant diseases: a single center study in 1989 sequential patients
    • Ludwig H, Endler G, Hübl W, et al. High prevalence of iron deficiency in patients with various hematological and malignant diseases: a single center study in 1989 sequential patients. Haematologica. 2010;95(Suppl 2):702.
    • (2010) Haematologica , vol.95 , pp. 702
    • Ludwig, H.1    Endler, G.2    Hübl, W.3
  • 28
    • 78049527939 scopus 로고    scopus 로고
    • Diagnosis and management of iron deficiency anemia in patients with IBD
    • Stein J, Hartmann F, Dignass AU. Diagnosis and management of iron deficiency anemia in patients with IBD. Nat Rev Gastroenterol Hepatol. 2010;7:599–610.
    • (2010) Nat Rev Gastroenterol Hepatol , vol.7 , pp. 599-610
    • Stein, J.1    Hartmann, F.2    Dignass, A.U.3
  • 29
    • 0037901018 scopus 로고    scopus 로고
    • Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial
    • Verdon F, Burnand B, Stubi CL, et al. Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial. BMJ. 2003;326:1124.
    • (2003) BMJ , vol.326 , pp. 1124
    • Verdon, F.1    Burnand, B.2    Stubi, C.L.3
  • 30
    • 1642393242 scopus 로고    scopus 로고
    • Tissue iron deficiency without anemia impairs adaptation in endurance capacity after aerobic training in previously untrained women
    • Brownlie Tt, Utermohlen V, Hinton PS, et al. Tissue iron deficiency without anemia impairs adaptation in endurance capacity after aerobic training in previously untrained women. Am J Clin Nutr. 2004;79:437–43.
    • (2004) Am J Clin Nutr , vol.79 , pp. 437-443
  • 31
    • 0030581590 scopus 로고    scopus 로고
    • Randomised study of cognitive effects of iron supplementation in non-anaemic iron-deficient adolescent girls
    • Bruner AB, Joffe A, Duggan AK, et al. Randomised study of cognitive effects of iron supplementation in non-anaemic iron-deficient adolescent girls. Lancet. 1996;348:992–6.
    • (1996) Lancet , vol.348 , pp. 992-996
    • Bruner, A.B.1    Joffe, A.2    Duggan, A.K.3
  • 32
    • 65349166375 scopus 로고    scopus 로고
    • Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention
    • Vamvakas EC, Blajchman MA. Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention. Blood. 2009;113:3406–17.
    • (2009) Blood , vol.113 , pp. 3406-3417
    • Vamvakas, E.C.1    Blajchman, M.A.2
  • 33
    • 53049093520 scopus 로고    scopus 로고
    • Efficacy of red blood cell transfusion in the critically ill: a systematic review of the literature
    • Marik PE, Corwin HL. Efficacy of red blood cell transfusion in the critically ill: a systematic review of the literature. Crit Care Med. 2008;36:2667–74.
    • (2008) Crit Care Med , vol.36 , pp. 2667-2674
    • Marik, P.E.1    Corwin, H.L.2
  • 34
    • 78651349191 scopus 로고    scopus 로고
    • Patient blood management—a new paradigm for transfusion medicine?
    • Thomson A, Farmer S, Hofmann A, et al. Patient blood management—a new paradigm for transfusion medicine? ISBT Science Series. 2009;4:423–35.
    • (2009) ISBT Science Series , vol.4 , pp. 423-435
    • Thomson, A.1    Farmer, S.2    Hofmann, A.3
  • 35
    • 53549099375 scopus 로고    scopus 로고
    • The silent risks of blood transfusion
    • Rawn J. The silent risks of blood transfusion. Curr Opin Anaesthesiol. 2008;21:664–8.
    • (2008) Curr Opin Anaesthesiol , vol.21 , pp. 664-668
    • Rawn, J.1
  • 36
    • 0031976199 scopus 로고    scopus 로고
    • Effect of perioperative blood transfusions on recurrence of colorectal cancer: meta-analysis stratified on risk factors
    • Amato AC, Pescatori M. Effect of perioperative blood transfusions on recurrence of colorectal cancer: meta-analysis stratified on risk factors. Dis Colon Rectum. 1998;41:570–85.
    • (1998) Dis Colon Rectum , vol.41 , pp. 570-585
    • Amato, A.C.1    Pescatori, M.2
  • 37
    • 55049119973 scopus 로고    scopus 로고
    • Bohlius J, Schmidlin K, Brillant C, et al. Erythropoietin or darbepoetin for patients with cancer–meta-analysis based on individual patient data. Cochrane Database Syst Rev. 2009;(3):CD007303
    • Bohlius J, Schmidlin K, Brillant C, et al. Erythropoietin or darbepoetin for patients with cancer–meta-analysis based on individual patient data. Cochrane Database Syst Rev. 2009;(3):CD007303.
  • 38
    • 0035366382 scopus 로고    scopus 로고
    • Clinical evaluation of once-weekly dosing of epoetin alfa in chemotherapy patients: improvements in hemoglobin and quality of life are similar to three-times-weekly dosing
    • Gabrilove JL, Cleeland CS, Livingston RB, et al. Clinical evaluation of once-weekly dosing of epoetin alfa in chemotherapy patients: improvements in hemoglobin and quality of life are similar to three-times-weekly dosing. J Clin Oncol. 2001;19:2875–82.
    • (2001) J Clin Oncol , vol.19 , pp. 2875-2882
    • Gabrilove, J.L.1    Cleeland, C.S.2    Livingston, R.B.3
  • 39
    • 0035367087 scopus 로고    scopus 로고
    • Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: results of a randomized, double-blind, placebo-controlled trial
    • Littlewood TJ, Bajetta E, Nortier JW, et al. Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: results of a randomized, double-blind, placebo-controlled trial. J Clin Oncol. 2001;19:2865–74.
    • (2001) J Clin Oncol , vol.19 , pp. 2865-2874
    • Littlewood, T.J.1    Bajetta, E.2    Nortier, J.W.3
  • 40
    • 66149150959 scopus 로고    scopus 로고
    • Treatment patterns and outcomes in the management of anaemia in cancer patients in Europe: findings from the anaemia cancer treatment (ACT) study
    • Ludwig H, Aapro M, Bokemeyer C, et al. Treatment patterns and outcomes in the management of anaemia in cancer patients in Europe: findings from the anaemia cancer treatment (ACT) study. Eur J Cancer. 2009;45:1603–15.
    • (2009) Eur J Cancer , vol.45 , pp. 1603-1615
    • Ludwig, H.1    Aapro, M.2    Bokemeyer, C.3
  • 41
    • 78549286047 scopus 로고    scopus 로고
    • American society of hematology/American society of clinical oncology clinical practice guideline update on the use of epoetin and darbepoetin in adult patients with cancer
    • Rizzo JD, Brouwers M, Hurley P, et al. American society of hematology/American society of clinical oncology clinical practice guideline update on the use of epoetin and darbepoetin in adult patients with cancer. Blood. 2010;116:4045–59.
    • (2010) Blood , vol.116 , pp. 4045-4059
    • Rizzo, J.D.1    Brouwers, M.2    Hurley, P.3
  • 42
    • 84951906508 scopus 로고    scopus 로고
    • EMA. Summary of Scientific Discussion. Accessed 2015
    • EMA. Summary of Scientific Discussion. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Scientific_Discussion_-_Variation/human/000332/WC500026146.pdf. Accessed 2015.
  • 43
    • 84951906841 scopus 로고    scopus 로고
    • FDA. Procrit Label, Epogen Label. Accessed 2015
    • FDA. Procrit Label, Epogen Label. http://www.accessdata.fda.gov/drugsatfda_docs/label/2010/103234s5199lbl.pdf. Accessed 2015.
  • 44
    • 84951904877 scopus 로고    scopus 로고
    • FDA. Aranesp (darbepoetin alfa) for injection. Accessed 2015
    • FDA. Aranesp (darbepoetin alfa) for injection. http://www.accessdata.fda.gov/drugsatfda_docs/label/2010/103951s5197lbl.pdf. Accessed 2015.
  • 45
    • 84951909161 scopus 로고    scopus 로고
    • NCCN. Cancer- and chemotherapy-induced anemia, Version 2.2014. (2014). Accessed 2015
    • NCCN. Cancer- and chemotherapy-induced anemia, Version 2.2014. http://www.nccn.org/professionals/physician_gls/pdf/anemia.pdf (2014). Accessed 2015.
  • 46
    • 65949107825 scopus 로고    scopus 로고
    • Ferric carboxymaltose: a review of its use in iron-deficiency anaemia
    • Lyseng-Williamson KA, Keating GM. Ferric carboxymaltose: a review of its use in iron-deficiency anaemia. Drugs. 2009;69:739–56.
    • (2009) Drugs , vol.69 , pp. 739-756
    • Lyseng-Williamson, K.A.1    Keating, G.M.2
  • 47
    • 77954319713 scopus 로고    scopus 로고
    • Erythropoiesis-stimulating agents in the treatment of anaemia in cancer patients: ESMO Clinical Practice Guidelines for use
    • Schrijvers D, De Samblanx H, Roila F. Erythropoiesis-stimulating agents in the treatment of anaemia in cancer patients: ESMO Clinical Practice Guidelines for use. Ann Oncol. 2010;21(Suppl 5):v244–247.
    • (2010) Ann Oncol , vol.21 , pp. v244-v247
    • Schrijvers, D.1    De Samblanx, H.2    Roila, F.3
  • 48
    • 84951906093 scopus 로고    scopus 로고
    • A reappraisal of the ESMO and EORTC guidelines for the management of anaemia and iron deficiency in patients with cancer-related or chemotherapy-induced anaemia, Ann Oncol
    • Aapro M, Beguin Y, Bokemeyer C, et al. A reappraisal of the ESMO and EORTC guidelines for the management of anaemia and iron deficiency in patients with cancer-related or chemotherapy-induced anaemia. Ann Oncol. 2015.
    • (2015) et al
    • Aapro, M.1    Beguin, Y.2    Bokemeyer, C.3
  • 49
    • 2142825053 scopus 로고    scopus 로고
    • Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: a multicenter, open-label, randomized trial
    • Auerbach M, Ballard H, Trout JR, et al. Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: a multicenter, open-label, randomized trial. J Clin Oncol. 2004;22:1301–7.
    • (2004) J Clin Oncol , vol.22 , pp. 1301-1307
    • Auerbach, M.1    Ballard, H.2    Trout, J.R.3
  • 50
    • 33847046008 scopus 로고    scopus 로고
    • Intravenous ferric gluconate significantly improves response to epoetin alfa versus oral iron or no iron in anemic patients with cancer receiving chemotherapy
    • Henry DH, Dahl NV, Auerbach M, et al. Intravenous ferric gluconate significantly improves response to epoetin alfa versus oral iron or no iron in anemic patients with cancer receiving chemotherapy. Oncologist. 2007;12:231–42.
    • (2007) Oncologist , vol.12 , pp. 231-242
    • Henry, D.H.1    Dahl, N.V.2    Auerbach, M.3
  • 51
    • 43249129663 scopus 로고    scopus 로고
    • Randomized, multicenter, controlled trial comparing the efficacy and safety of darbepoetin alpha administered every 3 weeks with or without intravenous iron in patients with chemotherapy-induced anemia
    • Bastit L, Vandebroek A, Altintas S, et al. Randomized, multicenter, controlled trial comparing the efficacy and safety of darbepoetin alpha administered every 3 weeks with or without intravenous iron in patients with chemotherapy-induced anemia. J Clin Oncol. 2008;26:1611–8.
    • (2008) J Clin Oncol , vol.26 , pp. 1611-1618
    • Bastit, L.1    Vandebroek, A.2    Altintas, S.3
  • 52
    • 43249121140 scopus 로고    scopus 로고
    • Randomized trial of intravenous iron supplementation in patients with chemotherapy-related anemia without iron deficiency treated with darbepoetin alpha
    • Pedrazzoli P, Farris A, Del Prete S, et al. Randomized trial of intravenous iron supplementation in patients with chemotherapy-related anemia without iron deficiency treated with darbepoetin alpha. J Clin Oncol. 2008;26:1619–25.
    • (2008) J Clin Oncol , vol.26 , pp. 1619-1625
    • Pedrazzoli, P.1    Farris, A.2    Del Prete, S.3
  • 53
    • 77956453903 scopus 로고    scopus 로고
    • Darbepoetin alfa 300 or 500 μg once every 3 weeks with or without intravenous iron in patients with chemotherapy-induced anemia
    • Auerbach M, Silberstein PT, Webb RT, et al. Darbepoetin alfa 300 or 500 μg once every 3 weeks with or without intravenous iron in patients with chemotherapy-induced anemia. Am J Hematol. 2010;85:655–63.
    • (2010) Am J Hematol , vol.85 , pp. 655-663
    • Auerbach, M.1    Silberstein, P.T.2    Webb, R.T.3
  • 54
    • 79951986687 scopus 로고    scopus 로고
    • Phase III, randomized study of the effects of parenteral iron, oral iron, or no iron supplementation on the erythropoietic response to darbepoetin alfa for patients with chemotherapy-associated anemia
    • Steensma DP, Sloan JA, Dakhil SR, et al. Phase III, randomized study of the effects of parenteral iron, oral iron, or no iron supplementation on the erythropoietic response to darbepoetin alfa for patients with chemotherapy-associated anemia. J Clin Oncol. 2011;29:97–105.
    • (2011) J Clin Oncol , vol.29 , pp. 97-105
    • Steensma, D.P.1    Sloan, J.A.2    Dakhil, S.R.3
  • 55
    • 84857055492 scopus 로고    scopus 로고
    • The relationship between serum hepcidin levels and clinical outcomes in patients with chemotherapy-associated anemia treated in a controlled trial
    • Steensma DP, Sasu BJ, Sloan JA, et al. The relationship between serum hepcidin levels and clinical outcomes in patients with chemotherapy-associated anemia treated in a controlled trial. ASCO Meeting Abstracts. 2011;29:9031.
    • (2011) ASCO Meeting Abstracts , vol.29 , pp. 9031
    • Steensma, D.P.1    Sasu, B.J.2    Sloan, J.A.3
  • 56
    • 84858129582 scopus 로고    scopus 로고
    • Evaluation of cost savings with ferric carboxymaltose in anemia treatment through its impact on erythropoiesis-stimulating agents and blood transfusion: French healthcare payer perspective
    • Luporsi E, Mahi L, Morre C, et al. Evaluation of cost savings with ferric carboxymaltose in anemia treatment through its impact on erythropoiesis-stimulating agents and blood transfusion: French healthcare payer perspective. J Med Econ. 2012;15:225–32.
    • (2012) J Med Econ , vol.15 , pp. 225-232
    • Luporsi, E.1    Mahi, L.2    Morre, C.3
  • 57
    • 84871400455 scopus 로고    scopus 로고
    • Intravenous iron supplementation for the treatment of chemotherapy-induced anaemia—systematic review and meta-analysis of randomised controlled trials
    • Gafter-Gvili A, Rozen-Zvi B, Vidal L, et al. Intravenous iron supplementation for the treatment of chemotherapy-induced anaemia—systematic review and meta-analysis of randomised controlled trials. Acta Oncol. 2013;52:18–29.
    • (2013) Acta Oncol , vol.52 , pp. 18-29
    • Gafter-Gvili, A.1    Rozen-Zvi, B.2    Vidal, L.3
  • 58
    • 84857059147 scopus 로고    scopus 로고
    • Addition of iron to erythropoiesis-stimulating agents in cancer patients: a meta-analysis of randomized trials
    • Petrelli F, Borgonovo K, Cabiddu M, et al. Addition of iron to erythropoiesis-stimulating agents in cancer patients: a meta-analysis of randomized trials. J Cancer Res Clin Oncol. 2012;138:179–87.
    • (2012) J Cancer Res Clin Oncol , vol.138 , pp. 179-187
    • Petrelli, F.1    Borgonovo, K.2    Cabiddu, M.3
  • 59
    • 33947312849 scopus 로고    scopus 로고
    • Effect of intravenously administered iron sucrose on the prevention of anemia in the cervical cancer patients treated with concurrent chemoradiotherapy
    • Kim YT, Kim SW, Yoon BS, et al. Effect of intravenously administered iron sucrose on the prevention of anemia in the cervical cancer patients treated with concurrent chemoradiotherapy. Gynecol Oncol. 2007;105:199–204.
    • (2007) Gynecol Oncol , vol.105 , pp. 199-204
    • Kim, Y.T.1    Kim, S.W.2    Yoon, B.S.3
  • 60
    • 75749138424 scopus 로고    scopus 로고
    • Blood transfusion reduction with intravenous iron in gynecologic cancer patients receiving chemotherapy
    • Dangsuwan P, Manchana T. Blood transfusion reduction with intravenous iron in gynecologic cancer patients receiving chemotherapy. Gynecol Oncol. 2010;116:522–5.
    • (2010) Gynecol Oncol , vol.116 , pp. 522-525
    • Dangsuwan, P.1    Manchana, T.2
  • 61
    • 84888301208 scopus 로고    scopus 로고
    • Prevention of blood transfusion with intravenous iron in gynecologic cancer patients receiving platinum-based chemotherapy
    • Athibovonsuk P, Manchana T, Sirisabya N. Prevention of blood transfusion with intravenous iron in gynecologic cancer patients receiving platinum-based chemotherapy. Gynecol Oncol. 2013;131:679–82.
    • (2013) Gynecol Oncol , vol.131 , pp. 679-682
    • Athibovonsuk, P.1    Manchana, T.2    Sirisabya, N.3
  • 62
    • 84883325476 scopus 로고    scopus 로고
    • Intravenous iron monotherapy for the treatment of non-iron-deficiency anemia in cancer patients undergoing chemotherapy: a pilot study
    • Abdel-Razeq H, Abbasi S, Saadi I, et al. Intravenous iron monotherapy for the treatment of non-iron-deficiency anemia in cancer patients undergoing chemotherapy: a pilot study. Drug Des Devel Ther. 2013;7:939–44.
    • (2013) Drug Des Devel Ther , vol.7 , pp. 939-944
    • Abdel-Razeq, H.1    Abbasi, S.2    Saadi, I.3
  • 63
    • 84873831349 scopus 로고    scopus 로고
    • Clinical experience with ferric carboxymaltose in the treatment of cancer- and chemotherapy-associated anaemia
    • Steinmetz T, Tschechne B, Harlin O, et al. Clinical experience with ferric carboxymaltose in the treatment of cancer- and chemotherapy-associated anaemia. Ann Oncol. 2013;24:475–82.
    • (2013) Ann Oncol , vol.24 , pp. 475-482
    • Steinmetz, T.1    Tschechne, B.2    Harlin, O.3
  • 65
    • 84860735219 scopus 로고    scopus 로고
    • Total dose iron dextran infusion in cancer patients: is it SaFe2 +. ?
    • Gilreath JA, Stenehjem DD, Rodgers GM. Total dose iron dextran infusion in cancer patients: is it SaFe2 +. ? J Natl Compr Canc Netw. 2012;10:669–76.
    • (2012) J Natl Compr Canc Netw , vol.10 , pp. 669-676
    • Gilreath, J.A.1    Stenehjem, D.D.2    Rodgers, G.M.3
  • 66
    • 77955701147 scopus 로고    scopus 로고
    • Effects of cellular iron deficiency on the formation of vascular endothelial growth factor and angiogenesis. Iron deficiency and angiogenesis
    • Eckard J, Dai J, Wu J, et al. Effects of cellular iron deficiency on the formation of vascular endothelial growth factor and angiogenesis. Iron deficiency and angiogenesis. Cancer Cell Int. 2010;10:28.
    • (2010) Cancer Cell Int , vol.10 , pp. 28
    • Eckard, J.1    Dai, J.2    Wu, J.3
  • 67
    • 84888060950 scopus 로고    scopus 로고
    • Darbepoetin-alfa and I.V. iron administration after autologous hematopoietic stem cell transplantation: a prospective randomized multicenter trial
    • Beguin Y, Maertens J, De Prijck B, et al. Darbepoetin-alfa and I.V. iron administration after autologous hematopoietic stem cell transplantation: a prospective randomized multicenter trial. Am J Hematol. 2013;88(12):990-6.
    • (2013) Am J Hematol , vol.88 , Issue.12 , pp. 990-996
    • Beguin, Y.1    Maertens, J.2    De Prijck, B.3
  • 68
    • 4344560350 scopus 로고    scopus 로고
    • Iron sucrose in hemodialysis patients: safety of replacement and maintenance regimens
    • Aronoff GR, Bennett WM, Blumenthal S, et al. Iron sucrose in hemodialysis patients: safety of replacement and maintenance regimens. Kidney Int. 2004;66:1193–8.
    • (2004) Kidney Int , vol.66 , pp. 1193-1198
    • Aronoff, G.R.1    Bennett, W.M.2    Blumenthal, S.3
  • 69
    • 84951905056 scopus 로고    scopus 로고
    • Centre for Evidence Based Medicine (CEBM). Levels of Evidence. (2009). Accessed 2015
    • Centre for Evidence Based Medicine (CEBM). Levels of Evidence. http://www.cebm.net/index.aspx?o=1025 (2009). Accessed 2015.
  • 70
    • 33646169029 scopus 로고    scopus 로고
    • Using iron agents
    • KDOQI. Clinical practice guidelines and clinical practice recommendations for anemia in chronic kidney disease—CPG and CPR 3.2. Using iron agents. Am J Kidney Dis. 2006;47:58–70.
    • (2006) Am J Kidney Dis , vol.47 , pp. 58-70
    • Clinical practice guidelines, K.D.O.Q.I.1
  • 71
    • 84951906966 scopus 로고    scopus 로고
    • Aapro MS, Beguin Y, Bokemeyer C, et al. Diagnosis, treatment, and use of intravenous iron for chemotherapy-induced anemia in Europe. J Clin Oncol 2011;29:ASCO-Abstract e19557
    • Aapro MS, Beguin Y, Bokemeyer C, et al. Diagnosis, treatment, and use of intravenous iron for chemotherapy-induced anemia in Europe. J Clin Oncol 2011;29:ASCO-Abstract e19557.
  • 72
    • 33644824809 scopus 로고    scopus 로고
    • Time-dependent associations between iron and mortality in hemodialysis patients
    • Kalantar-Zadeh K, McAllister CJ, Regidor DL, et al. Time-dependent associations between iron and mortality in hemodialysis patients. J Am Soc Nephrol. 2005;16:3070–80.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3070-3080
    • Kalantar-Zadeh, K.1    McAllister, C.J.2    Regidor, D.L.3


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