Delirium superimposed on dementia: A survey of delirium specialists shows a lack of consensus in clinical practice and research studies

International Psychogeriatrics

Volumn 28, Issue 5, 2016, Pages 853-861

  Richardson, Sarah ^a   Teodorczuk, Andrew ^b   Bellelli, Giuseppe ^c,d   Davis, Daniel H J ^e   Neufeld, Karin J ^f   Kamholz, Barbara A ^g   Trabucchi, Marco ^d,h   Maclullich, Alasdair M J ⁱ   Morandi, Alessandro ^d,j  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c SAN GERARDO HOSPITAL   (Italy)

^d GERIATRIC RESEARCH GROUP   (Italy)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h UNIVERSITY OF ROME TOR VERGATA   (Italy)

ⁱ UNIVERSITY OF EDINBURGH   (United Kingdom)

^j Aged Care Fondazione Camplani Hospital   (Italy)

more..

Author keywords

clinical practice; delirium; delirium superimposed on dementia; dementia; European delirium association; knowledge; survey

Indexed keywords

ALERTNESS; AROUSABILITY; ARTICLE; ATTENTION; CLINICAL PRACTICE; COGNITION; COGNITIVE FLUCTUATION; CONFUSION ASSESSMENT METHOD; DELIRIUM; DEMENTIA; DEMENTIA ASSESSMENT; DIFFUSE LEWY BODY DISEASE; DISEASE ASSESSMENT; DSM-5; HEALTH SURVEY; HUMAN; LIKERT SCALE; MEDICAL SPECIALIST; MINI MENTAL STATE EXAMINATION; MOTOR FLUCTUATION; PHYSICIAN ATTITUDE; ATTITUDE TO HEALTH; CONSENSUS; MOTOR ACTIVITY; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY; QUESTIONNAIRE; SEVERITY OF ILLNESS INDEX; STANDARDS;

ATTENTION; COGNITION; CONSENSUS; DELIRIUM; DEMENTIA; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; MOTOR ACTIVITY; PSYCHIATRIC STATUS RATING SCALES; SEVERITY OF ILLNESS INDEX; SURVEYS AND QUESTIONNAIRES;

EID: 84951274315     PISSN: 10416102     EISSN: 1741203X     Source Type: Journal    
DOI: 10.1017/S1041610215002288     Document Type: Article

References (48)

1. Albert, S. M., Costa, R., Merchant, C., Small, S., Jenders, R. A., and Stern, Y. (1999). Hospitalization and Alzheimer's disease: results from a community-based study. Journals of Gerontology: Series A Biological Sciences and Medical Sciences, 54, M267-M271. doi:10.1093/gerona/54.5.M267
2. American Psychiatric Association (2000). Diagnostic and Statistical Manual of Mental Disorders, 4th Text Revision (DSM-IV-TR). Washington, DC: American Psychiatric Association
3. American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders, 5th edn, (DSM-5). Washington, DC: American Psychiatric Association
4. Ballard, C., Corbett, A., and Howard, R. (2014). Prescription of antipsychotics in people with dementia. British Journal Psychiatry, 205, 4-5. doi:10.1192/bjp.bp.113.128710
5. Ballard, C., et al. (2009). Management of agitation and aggression associated with Alzheimer disease. Nature Reviews. Neurology, 5, 245-255. doi:10.1038/nrneurol.2009.39
6. Bellelli, G., Frisoni, G. B., Turco, R., Lucchi, E., Magnifico, F., and Trabucchi, M. (2007). Delirium superimposed on dementia predicts 12-month survival in elderly patients discharged from a postacute rehabilitation facility. Journals of Gerontology Series A-Biological Sciences & Medical Sciences, 62, 1306-1309. doi:10.1093/gerona/62.11.1306
7. Bellelli, G., Speciale, S., Morghen, S., Torpilliesi, T., Turco, R., and Trabucchi, M. (2011). Are fluctuations in motor performance a diagnostic sign of delirium' Journal of the American Medical Directors Association, 12, 578-583. doi:10.1016/j.jamda.2010.04.010
8. Bergeron, N., Dubois, M. J., Dumont, M., Dial, S., and Skrobik, Y. (2001). Intensive care delirium screening checklist: evaluation of a new screening tool. Intensive Care Medicine, 27, 859-864
9. Brown, L. J., Fordyce, C., Zaghdani, H., Starr, J. M., and MacLullich, A. M. (2011). Detecting deficits of sustained visual attention in delirium. Journal of Neurology, Neurosurgery and Psychiatry, 82, 1334-1340. doi:10.1136/jnnp.2010.208827
10. Collins, N., Blanchard, M. R., Tookman, A., and Sampson, E. L. (2010). Detection of delirium in the acute hospital. Age and Ageing, 39, 131-135
11. Davis, D. H., et al. (2012). Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study. Brain, 135, 2809-2816
12. Ely, E. W., et al. (2001). Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). Journal of the American Medical Association, 286, 2703-2710
13. Fick, D. M., Agostini, J. V., and Inouye, S. K. (2002). Delirium superimposed on dementia: a systematic review. Journal of the American Geriatric Society, 50, 1723-1732. doi:10.1046/j.1532-5415.2002.50468.x
14. Fick, D. M., Hodo, D. M., Lawrence, F., and Inouye, S. K. (2007). Recognizing delirium superimposed on dementia: assessing nurses' knowledge using case vignettes. Journal of Gerontological Nursing, 33, 40-49
15. Fick, D. M., Steis, M. R., Waller, J. L., and Inouye, S. K. (2013). Delirium superimposed on dementia is associated with prolonged length of stay and poor outcomes in hospitalized older adults. Journal of Hospital Medicine, 8, 500-505. doi:10.1002/jhm.2077
16. Fong, T. G., Davis, D., Growdon, M. E., Albuquerque, A., and Inouye, S. K. (2015). The interface between delirium and dementia in elderly adults. The Lancet, 14, 823-832. doi:10.1016/S1474-4422(15)00101-5
17. Fong, T. G., et al. (2009). Delirium accelerates cognitive decline in Alzheimer disease. Neurology, 72, 1570-1575
18. Givens, J. L., Sanft, T. B., and Marcantonio, E. R. (2008). Functional recovery after hip fracture: the combined effects of depressive symptoms, cognitive impairment, and delirium. Journal of the American Geriatrics Society, 56, 1075-1079. doi:10.1111/j.1532-5415.2008.01711.x
19. Han, J. H., et al. (2014). Impaired arousal at initial presentation predicts 6-month mortality: an analysis of 1084 acutely ill older patients. Journal of Hospital Medicine, 9, 772-778
20. Hasegawa, N., et al. (2013). Prevalence of delirium among outpatients with dementia. International Psychogeriatrics, 25, 1877-1833. doi:10.1017/S1041610213001191
21. Holmes, J. andHouse, A. (2000). Psychiatric illness predicts poor outcome after surgery for hip fracture: a prospective cohort study. Psychological Medicine, 30, 921-929
22. Inouye, S. K., et al. (1999). A multicomponent intervention to prevent delirium in hospitalized older patients. New England Journal of Medicine, 340, 669-676
23. Inouye, S. K., van Dyck, C. H., Alessi, C. A., Balkin, S., Siegal, A. P., and Horwitz, R. I. (1990). Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Annals of Internal Medicine, 113, 941-948
24. Jackson, T. A., Wilson, D., Richardson, S., and Lord, J. M. (2015). Predicting outcome in older hospital patients with delirium: a systematic literature review. International Journal of Geriatric Psychiatry, doi:10.1002/gps.4344
25. Landreville, P., Voyer, P., and Carmichael, P.-H. (2013). Relationship between delirium and behavioural symptoms of dementia. International Psychogeriatrics, 25, 635-643. doi:10.1017/S1041610212002232
26. MacKnight, C., and Rockwood, K. (1995). A hierarchical assessment of balance and mobility. Age and Ageing, 24, 126-130
27. MacLullich, A. M., Meagher, D. J., Laurila, J. V., and Kalisvaart, K. J. (2007). The European delirium association. Journal of Psychosomatic Research, 62, 397-398
28. Meagher, D. J., Leonard, M., Donnelly, S., Conroy, M., Saunders, J., and Trzepacz, P. T. (2010). A comparison of neuropsychiatric and cognitive profiles in delirium, dementia, comorbid delirium-dementia and cognitively intact controls. Journal of Neurology, Neurosurgery and Psychiatry, 81, 876-881. doi:10.1136/jnnp.2009.200956
29. Morandi, A., et al. (2012). Tools to detect delirium superimposed on dementia: a systematic review. Journal of the American Geriatrics Society, 60, 2005-2013. doi:10.1111/j.1532-5415.2012.04199.x
30. Morandi, A., et al. (2013). Consensus and variations in opinions on delirium care: a survey of European delirium specialists. International Psychogeriatriatrics, 25, 2067-2075. doi:10.1017/S1041610213001415
31. Morandi, A., et al. (2014). Delirium superimposed on dementia strongly predicts worse outcomes in older rehabilitation inpatients. Journal of the American Medical Directors Association, 15, 349-354. doi:10.1016/j.jamda.2013.12.084
32. National Institute for Health and Clinical Excellence (2010). Delirium: diagnosis, prevention and managment. Available at: http://www.nice.org.uk/CG103; last accessed 14 August 2015
33. Neef, D., and Walling, A. D. (2006). Dementia with Lewy bodies: an emerging disease. American Family Physician, 73, 1223-1229
34. Partridge, J. S. L., Martin, F. C., Harari, D., and Dhesi, J. K. (2013). The delirium experience: what is the effect on patients, relatives and staff and what can be done to modify this' International Journal of Geriatric Psychiatry, 28, 804-812. doi:10.1002/gps.3900
35. Robinson, L., Tang, E., and Taylor, J.-P. (2015). Dementia: timely diagnosis and early intervention. British Medical Journal, 350, h3029. doi:http://dx.doi.org/10.1136/bmj.h3029
36. Ryan, D. J., et al. (2013). Delirium in an adult acute hospital population: predictors, prevalence and detection. British Medical Journal Open, 3, e001772. doi:10.1136/bmjopen-2012-001772
37. Sampson, E. L., Blanchard, M. R., Jones, L., Tookman, A., and King, M. (2009). Dementia in the acute hospital: prospective cohort study of prevalence and mortality. British Journal of Psychiatry, 195, 61-66. doi:10.1192/bjp.bp.108.055335
38. Savva, G. M., and Arthur, A. (2015). Who has undiagnosed dementia' A cross-sectional analysis of participants of the aging, demographics and memory study. Age and Ageing, 44, 642-647. doi:10.1093/ageing/afv020
39. Sessler, C. N., et al. (2002). The richmond agitation-sedation scale. American Journal of Respiratory and Critical Care Medicine, 166, 1338-1344
40. Teasdale, G., and Jennett, B. (1974). Assessment of coma and impaired consciousness. A practical scale. Lancet, 2, 81-84
41. Tieges, Z., Brown, L. J. E. andMacLullich, A. M. J. (2014). Objective assessment of attention in delirium: a narrative review. International Journal of Geriatric Psychiatry, 29, 1185-1197. doi:10.1002/gps.4131
42. Tieges, Z., McGrath, A., Hall, R. J., and Maclullich, A. M. (2013). Abnormal level of arousal as a predictor of delirium and inattention: an exploratory study. American Journal of Geriatric Psychiatry, 21, 1244-1253
43. Trzepacz, P. T., Mittal, D., Torres, R., Kanary, K., Norton, J., and Jimerson, N. (2001). Validation of the delirium rating scale-revised-98: comparison with the delirium rating scale and the cognitive test for delirium. The Journal of Neuropsychiatry & Clinical Neurosciences, 13, 229-242
44. Vardy, E., Holt, R., Gerhard, A., Richardson, A., Snowden, J., and Neary, D. (2014). History of a suspected delirium is more common in dementia with Lewy bodies than Alzheimer's disease: a retrospective study. International Journal of Geriatric Psychiatry, 29, 178-181. doi:10.1002/gps.3986
45. Voyer, P., Cole, M. G., McCusker, J., and Belzile, E. (2006). Prevalence and symptoms of delirium superimposed on dementia. Clinical Nursing Research, 15, 46-66
46. Voyer, P., Richard, S., Doucet, L., Danjou, C., and Carmichael, P.-H. (2008). Detection of delirium by nurses among long-Term care residents with dementia. BioMedCentral Nursing, 7, 4-4
47. Witlox, J., Eurelings, L. S., de Jonghe, J. F., Kalisvaart, K. J., Eikelenboom, P., and van Gool, W. A. (2010). Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-Analysis. Journal of the American Medical Association, 304, 443-451. doi:10.1001/jama.2010.1013
48. Yevchak, A. M., et al. (2015). Impaired arousal in older adults is associated with prolonged hospital stay and discharge to skilled nursing facility. Journal of the American Medical Directors Association, 16, 586-589