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Volumn 11, Issue 2, 2016, Pages 371-380

Efficacy and safety of bevacizumab for the treatment of glioblastoma (Review)

Author keywords

Anti angiogenic; Bevacizumab; Glioblastoma; Vascular endothelial growth factor

Indexed keywords

ANTICONVULSIVE AGENT; BEVACIZUMAB; IRINOTECAN; TEMOZOLOMIDE; VASCULOTROPIN;

EID: 84951098706     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2015.2947     Document Type: Review
Times cited : (13)

References (68)
  • 2
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Wen PY and Kesari S: Malignant gliomas in adults. N Engl J Med 359: 492-507, 2008.
    • (2008) N Engl J Med , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 4
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
    • Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, Janzer RC, Ludwin SK, Allgeier A, Fisher B, Belanger K, et al: Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10: 459-466, 2009.
    • (2009) Lancet Oncol , vol.10 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3    van den Bent, M.J.4    Taphoorn, M.J.5    Janzer, R.C.6    Ludwin, S.K.7    Allgeier, A.8    Fisher, B.9    Belanger, K.10
  • 5
    • 34249100230 scopus 로고    scopus 로고
    • Chemotherapy for low-grade gliomas: Emerging consensus on its benefits
    • Wen PY and DeAngelis LM: Chemotherapy for low-grade gliomas: Emerging consensus on its benefits. Neurology 68: 1762-1763, 2007.
    • (2007) Neurology , vol.68 , pp. 1762-1763
    • Wen, P.Y.1    DeAngelis, L.M.2
  • 7
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent
    • Folkman J: What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82: 4-6, 1990.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 8
    • 14644440555 scopus 로고    scopus 로고
    • Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
    • Hicklin DJ and Ellis LM: Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 23: 1011-1027, 2005.
    • (2005) J Clin Oncol , vol.23 , pp. 1011-1027
    • Hicklin, D.J.1    Ellis, L.M.2
  • 9
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J: Tumor angiogenesis: Therapeutic implications. N Engl J Med 285: 1182-1186, 1971.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 10
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D and Folkman J: Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353-364, 1996.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 11
    • 0037267544 scopus 로고    scopus 로고
    • Targeting the tumor blood vessel network to enhance the efficacy of radiation therapy
    • Siemann DW and Shi W: Targeting the tumor blood vessel network to enhance the efficacy of radiation therapy. Semin Radiat Oncol 13: 53-61, 2003.
    • (2003) Semin Radiat Oncol , vol.13 , pp. 53-61
    • Siemann, D.W.1    Shi, W.2
  • 12
    • 67649200247 scopus 로고    scopus 로고
    • Anti-VEGF therapies for malignant glioma: Treatment effects and escape mechanisms
    • Miletic H, Niclou SP, Johansson M and Bjerkvig R: Anti-VEGF therapies for malignant glioma: Treatment effects and escape mechanisms. Expert Opin Ther Targets 13: 455-468, 2009.
    • (2009) Expert Opin Ther Targets , vol.13 , pp. 455-468
    • Miletic, H.1    Niclou, S.P.2    Johansson, M.3    Bjerkvig, R.4
  • 13
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP and LeCouter J: The biology of VEGF and its receptors. Nat Med 9: 669-676, 2003.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 14
    • 78650940726 scopus 로고    scopus 로고
    • Antiangiogenic agents in the treatment of recurrent or newly diagnosed glioblastoma: Analysis of single-agent and combined modality approaches
    • Beal K, Abrey LE and Gutin PH: Antiangiogenic agents in the treatment of recurrent or newly diagnosed glioblastoma: Analysis of single-agent and combined modality approaches. Radiat Oncol 6: 2, 2011.
    • (2011) Radiat Oncol , vol.6 , pp. 2
    • Beal, K.1    Abrey, L.E.2    Gutin, P.H.3
  • 19
    • 83455217896 scopus 로고    scopus 로고
    • Bevacizumab in glioblastoma multiforme
    • Specenier P: Bevacizumab in glioblastoma multiforme. Expert Rev Anticancer Ther 12: 9-18, 2012.
    • (2012) Expert Rev Anticancer Ther , vol.12 , pp. 9-18
    • Specenier, P.1
  • 21
    • 32944482137 scopus 로고    scopus 로고
    • Bevacizumab and CPT-11 in the treatment of relapsed malignant glioma
    • Stark-Vance V: Bevacizumab and CPT-11 in the treatment of relapsed malignant glioma. Neuro Oncol 7: 369, 2005.
    • (2005) Neuro Oncol , vol.7 , pp. 369
    • Stark-Vance, V.1
  • 26
    • 77956666382 scopus 로고    scopus 로고
    • The BRAIN Investigators:Updated safety and survival of patients with relapsed glioblastoma treated with bevacizumab in the BRAIN study
    • Cloughesy T, VJ, Day B, Das A and Friedman HS: The BRAIN Investigators:Updated safety and survival of patients with relapsed glioblastoma treated with bevacizumab in the BRAIN study. J Clin Oncol 28 (15 Suppl): 181s, 2010.
    • (2010) J Clin Oncol , vol.28 , pp. 181
    • Cloughesy, T.V.J.1    Day, B.2    Das, A.3    Friedman, H.S.4
  • 27
  • 28
    • 75449088610 scopus 로고    scopus 로고
    • FDA drug approval summary: Bevacizumab (Avastin) as treatment of recurrent glioblastoma multiforme
    • Cohen MH, Shen YL, Keegan P and Pazdur R: FDA drug approval summary: Bevacizumab (Avastin) as treatment of recurrent glioblastoma multiforme. Oncologist 14: 1131-1138, 2009.
    • (2009) Oncologist , vol.14 , pp. 1131-1138
    • Cohen, M.H.1    Shen, Y.L.2    Keegan, P.3    Pazdur, R.4
  • 29
    • 75049085069 scopus 로고    scopus 로고
    • Salvage therapy with single agent bevacizumab for recurrent glioblastoma
    • Chamberlain MC and Johnston SK: Salvage therapy with single agent bevacizumab for recurrent glioblastoma. J Neurooncol 96: 259-269, 2010.
    • (2010) J Neurooncol , vol.96 , pp. 259-269
    • Chamberlain, M.C.1    Johnston, S.K.2
  • 34
    • 84868304292 scopus 로고    scopus 로고
    • A meta-analysis of bevacizumab alone and in combination with irinotecan in the treatment of patients with recurrent glioblastoma multiforme
    • Zhang G, Huang S and Wang Z: A meta-analysis of bevacizumab alone and in combination with irinotecan in the treatment of patients with recurrent glioblastoma multiforme. J Clin Neurosci 19: 1636-1640, 2012.
    • (2012) J Clin Neurosci , vol.19 , pp. 1636-1640
    • Zhang, G.1    Huang, S.2    Wang, Z.3
  • 35
    • 79958206587 scopus 로고    scopus 로고
    • Approval denied by the european medicines agency (EMA) for bevacizumab in the treatment of high-grade glioma recurrence: A good idea or a grave error
    • Balañá C, Etxaniz O, Bugés C and Martínez A: Approval denied by the european medicines agency (EMA) for bevacizumab in the treatment of high-grade glioma recurrence: A good idea or a grave error? Clin Transl Oncol 13: 209-210, 2011.
    • (2011) Clin Transl Oncol , vol.13 , pp. 209-210
    • Balañá, C.1    Etxaniz, O.2    Bugés, C.3    Martínez, A.4
  • 36
    • 79951984402 scopus 로고    scopus 로고
    • Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme
    • Lai A, Tran A, Nghiemphu PL, Pope WB, Solis OE, Selch M, Filka E, Yong WH, Mischel PS, Liau LM, et al: Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme. J Clin Oncol 29: 142-148, 2011.
    • (2011) J Clin Oncol , vol.29 , pp. 142-148
    • Lai, A.1    Tran, A.2    Nghiemphu, P.L.3    Pope, W.B.4    Solis, O.E.5    Selch, M.6    Filka, E.7    Yong, W.H.8    Mischel, P.S.9    Liau, L.M.10
  • 40
    • 84863794415 scopus 로고    scopus 로고
    • Management of treatment-associated toxicites of anti-angiogenic therapy in patients with brain tumors
    • Armstrong TS, Wen PY, Gilbert MR and Schiff D: Management of treatment-associated toxicites of anti-angiogenic therapy in patients with brain tumors. Neuro Oncol 14: 1203-1214, 2012.
    • (2012) Neuro Oncol , vol.14 , pp. 1203-1214
    • Armstrong, T.S.1    Wen, P.Y.2    Gilbert, M.R.3    Schiff, D.4
  • 44
    • 58149456505 scopus 로고    scopus 로고
    • Efficacy, safety and patterns of response and recurrence in patients with recurrent high-grade gliomas treated with bevacizumab plus irinotecan
    • Zuniga RM, Torcuator R, Jain R, Anderson J, Doyle T, Ellika S, Schultz L and Mikkelsen T: Efficacy, safety and patterns of response and recurrence in patients with recurrent high-grade gliomas treated with bevacizumab plus irinotecan. J Neurooncol 91: 329-336, 2009.
    • (2009) J Neurooncol , vol.91 , pp. 329-336
    • Zuniga, R.M.1    Torcuator, R.2    Jain, R.3    Anderson, J.4    Doyle, T.5    Ellika, S.6    Schultz, L.7    Mikkelsen, T.8
  • 46
    • 63049088767 scopus 로고    scopus 로고
    • Renal effects of anti-angiogenesis therapy: Update for the internist
    • Gurevich F and Perazella MA: Renal effects of anti-angiogenesis therapy: Update for the internist. Am J Med 122: 322-328, 2009.
    • (2009) Am J Med , vol.122 , pp. 322-328
    • Gurevich, F.1    Perazella, M.A.2
  • 47
    • 33846638744 scopus 로고    scopus 로고
    • Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: Systematic review and meta-analysis
    • Zhu X, Wu S, Dahut WL and Parikh CR: Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: Systematic review and meta-analysis. Am J Kidney Dis 49: 186-193, 2007.
    • (2007) Am J Kidney Dis , vol.49 , pp. 186-193
    • Zhu, X.1    Wu, S.2    Dahut, W.L.3    Parikh, C.R.4
  • 48
    • 77955638572 scopus 로고    scopus 로고
    • Bevacizumab increases risk for severe proteinuria in cancer patients
    • Wu S, Kim C, Baer L and Zhu X: Bevacizumab increases risk for severe proteinuria in cancer patients. J Am Soc Nephrol 21: 1381-1389, 2010.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1381-1389
    • Wu, S.1    Kim, C.2    Baer, L.3    Zhu, X.4
  • 49
    • 84876325620 scopus 로고    scopus 로고
    • Bevacizumab in high-grade gliomas: A review of its uses, toxicity assessment, and future treatment challenges
    • Rahmathulla G, Hovey EJ, Hashemi-Sadraei N and Ahluwalia MS: Bevacizumab in high-grade gliomas: A review of its uses, toxicity assessment, and future treatment challenges. Onco Targets Ther 6: 371-389, 2013.
    • (2013) Onco Targets Ther , vol.6 , pp. 371-389
    • Rahmathulla, G.1    Hovey, E.J.2    Hashemi-Sadraei, N.3    Ahluwalia, M.S.4
  • 51
    • 36849019200 scopus 로고    scopus 로고
    • Bevacizumab and irinotecan in patients (pts) with recurrent glioblastoma multiforme (GBM)
    • Raval S, HS and Dorsett L: Bevacizumab and irinotecan in patients (pts) with recurrent glioblastoma multiforme (GBM). J Clin Oncol 25 (Suppl 18): 2078, 2007.
    • (2007) J Clin Oncol , vol.25 , pp. 2078
    • Raval, S.H.S.1    Dorsett, L.2
  • 52
    • 43049124382 scopus 로고    scopus 로고
    • Treatment with bevacizumab and irinotecan for recurrent high-grade glial tumors
    • Bokstein F, Shpigel S and Blumenthal DT: Treatment with bevacizumab and irinotecan for recurrent high-grade glial tumors. Cancer 112: 2267-2273, 2008.
    • (2008) Cancer , vol.112 , pp. 2267-2273
    • Bokstein, F.1    Shpigel, S.2    Blumenthal, D.T.3
  • 53
    • 84873084779 scopus 로고    scopus 로고
    • Bevacizumab (B) with irinotecan (I) in recurrent glioblastoma (GBM): A national retrospective cohort of the ANOCEF (Association Des Neuro-Oncologues D'Expression Française) group
    • Taillibert S, Hoang-Xuan K, Barrie M, Guiu S, Chauffert B, Cartalat-Carel S, Taillandier L, Fabbro M, Laigre M, Guillamo JS et al; ANOCEF group: Bevacizumab (B) with irinotecan (I) in recurrent glioblastoma (GBM): A national retrospective cohort of the ANOCEF (Association Des Neuro-Oncologues D'Expression Française) group. Neuro Oncol 12 (Suppl 4): iv52-iv53, 2010.
    • (2010) Neuro Oncol , vol.12 , pp. iv52-iv53
    • Taillibert, S.1    Hoang-Xuan, K.2    Barrie, M.3    Guiu, S.4    Chauffert, B.5    Cartalat-Carel, S.6    Taillandier, L.7    Fabbro, M.8    Laigre, M.9    Guillamo, J.S.10
  • 54
    • 84951013721 scopus 로고    scopus 로고
    • Updated results of a phase II trial of bevacizumab and irinotecan in relapsed high-grade glioma
    • Keyrouz VF, Elias E, Chahine GY, Comair YG, Dimassi H and Kamar FG: Updated results of a phase II trial of bevacizumab and irinotecan in relapsed high-grade glioma. Neuro Oncol 12 (Suppl 3): iii47, 2010.
    • (2010) Neuro Oncol , vol.12 , pp. iii47
    • Keyrouz, V.F.1    Elias, E.2    Chahine, G.Y.3    Comair, Y.G.4    Dimassi, H.5    Kamar, F.G.6
  • 55
    • 33646675851 scopus 로고    scopus 로고
    • MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy
    • Pope WB, Lai A, Nghiemphu P, Mischel P and Cloughesy TF: MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy. Neurology 66: 1258-1260, 2006.
    • (2006) Neurology , vol.66 , pp. 1258-1260
    • Pope, W.B.1    Lai, A.2    Nghiemphu, P.3    Mischel, P.4    Cloughesy, T.F.5
  • 59
    • 80053142607 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab with fotemustine in recurrent glioblastoma: Final results of a multicenter study of AINO (Italian Association of Neuro-oncology)
    • Soffietti R, Trevisan E, Ruda R, Bertero L, Bosa C, Fabrini MG and Lolli I: Phase II trial of bevacizumab with fotemustine in recurrent glioblastoma: Final results of a multicenter study of AINO (Italian Association of Neuro-oncology). J Clin Oncol 29: 2011.
    • (2011) J Clin Oncol , vol.29
    • Soffietti, R.1    Trevisan, E.2    Ruda, R.3    Bertero, L.4    Bosa, C.5    Fabrini, M.G.6    Lolli, I.7
  • 61
  • 65
    • 84874655851 scopus 로고    scopus 로고
    • Re-irradiation with and without bevacizumab as salvage therapy for recurrent or progressive high-grade gliomas
    • Hundsberger T, Brügge D, Putora PM, Weder P, Weber J and Plasswilm L: Re-irradiation with and without bevacizumab as salvage therapy for recurrent or progressive high-grade gliomas. J Neurooncology 112: 133-139, 2013.
    • (2013) J Neurooncology , vol.112 , pp. 133-139
    • Hundsberger, T.1    Brügge, D.2    Putora, P.M.3    Weder, P.4    Weber, J.5    Plasswilm, L.6
  • 67
    • 84859628071 scopus 로고    scopus 로고
    • Phase II study of concurrent radiation therapy, temozolomide and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma
    • Hainsworth JD, Shih KC, Shepard GC, Tillinghast GW, Brinker BT and Spigel DR: Phase II study of concurrent radiation therapy, temozolomide and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma. Clin Adv Hematol Oncol 10: 240-246, 2012.
    • (2012) Clin Adv Hematol Oncol , vol.10 , pp. 240-246
    • Hainsworth, J.D.1    Shih, K.C.2    Shepard, G.C.3    Tillinghast, G.W.4    Brinker, B.T.5    Spigel, D.R.6
  • 68
    • 84893126414 scopus 로고    scopus 로고
    • Bevacizumab, irinotecan and radiotherapy versus standard temozolomide and radiotherapy in newly diagnosed, MGMT non-methylated glioblastoma patients: Updated results from the randomized multicenter GLARIUS trial
    • Herrlinger U, Schafer N, Steinbach JP, Weyerbrock A, Hau P, Goldbrunner R, Friedrich F, Stockhammer F, Ringel F, Braun C, et al: Bevacizumab, irinotecan and radiotherapy versus standard temozolomide and radiotherapy in newly diagnosed, MGMT non-methylated glioblastoma patients: Updated results from the randomized multicenter GLARIUS trial. European J Cancer 49: S774, 2013.
    • (2013) European J Cancer , vol.49
    • Herrlinger, U.1    Schafer, N.2    Steinbach, J.P.3    Weyerbrock, A.4    Hau, P.5    Goldbrunner, R.6    Friedrich, F.7    Stockhammer, F.8    Ringel, F.9    Braun, C.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.