Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex

EMBO Journal

Volumn 34, Issue 23, 2015, Pages 2937-2952

  Lye, Ming F ^a   Sharma, Mayuri ^a   El Omari, Kamel ^b   Filman, David J ^a   Schuermann, Jonathan P ^c   Hogle, James M ^a   Coen, Donald M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Cornell University ^*  (United States)

Author keywords

Bergerat fold; crystal structure; interaction interface; nuclear egress complex; zinc finger

Indexed keywords

ANTIVIRUS AGENT; HETERODIMER; METALLOPROTEIN; MUTANT PROTEIN; NUCLEAR EGRESS COMPLEX; NUCLEOTIDE BINDING PROTEIN; UL50 PROTEIN; UL53 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; ZINC; UL53 PROTEIN, HUMAN HERPESVIRUS 1; VIRAL PROTEIN;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DIMERIZATION; GENETIC TRANSFECTION; HUMAN CYTOMEGALOVIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; VIRUS GENE; VIRUS MUTANT; VIRUS REPLICATION; CHEMISTRY; GENETICS; HERPESVIRIDAE; METABOLISM; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; VIRUS GENOME; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; GENOME, VIRAL; HERPESVIRIDAE; PROTEIN STRUCTURE, SECONDARY; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84950277486     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201592651     Document Type: Article

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