Dominant negative mutants of the murine cytomegalovirus M53 gene block nuclear egress and inhibit capsid maturation

Journal of Virology

Volumn 84, Issue 18, 2010, Pages 9035-9046

  Popa, Mirela ^a   Ruzsics, Zsolt ^a   Lötzerich, Mark ^a,c   Dölken, Lars ^a   Buser, Christopher ^b,d   Walther, Paul ^b   Koszinowski, Ulrich H ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF ULM   (Germany)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; NUCLEAR EGRESS COMPLEX PROTEIN; PROTEIN M50; PROTEIN M53; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS VECTOR; CAPSID PROTEIN;

ALLELE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN 3T3; COMPETITIVE INHIBITION; CONTROLLED STUDY; CYTOMEGALOVIRUS; DNA PACKAGING; DOMINANT NEGATIVE MUTATION; EMBRYO; EXPRESSION VECTOR; GENE IDENTIFICATION; HERPES SIMPLEX VIRUS 1; MOUSE; NONHUMAN; NUCLEAR EGRESS COMPLEX; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHENOTYPE; PRIORITY JOURNAL; STEADY STATE; VIRAL GENE DELIVERY SYSTEM; VIRAL PHENOMENA AND FUNCTIONS; VIRUS CAPSID; VIRUS GENE; VIRUS GENOME; VIRUS ISOLATION; VIRUS MUTANT; VIRUS MUTATION; VIRUS REPLICATION; ACTIVE TRANSPORT; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; CONFOCAL MICROSCOPY; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; MISSENSE MUTATION; MOLECULAR GENETICS; MUROMEGALOVIRUS; PHYSIOLOGY; TRANSMISSION ELECTRON MICROSCOPY; VIRUS ASSEMBLY;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SEQUENCE; ANIMALS; CAPSID PROTEINS; CELLS, CULTURED; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUROMEGALOVIRUS; MUTATION, MISSENSE; VIRAL PROTEINS; VIRUS ASSEMBLY; VIRUS REPLICATION;

EID: 77956019599     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00681-10     Document Type: Article

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