Increased toxin expression in a Clostridium difficile mfd mutant Microbe-host interactions and microbial pathogenicity

BMC Microbiology

Volumn 15, Issue 1, 2015, Pages

  Willing, Stephanie E ^a,b   Richards, Emma J ^a   Sempere, Lluis ^b   Dale, Aaron G ^a   Cutting, Simon M ^b   Fairweather, Neil F ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

CcpA; Clostridium difficile; mfd; Toxin A; Toxin B; Transcription repair coupling factor; Transcriptional roadblock

Indexed keywords

BACTERIAL RNA; CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; POLYSACCHARIDE; RNA POLYMERASE; BACTERIAL PROTEIN; BACTERIAL TOXIN; ENTEROTOXIN; TCDA PROTEIN, CLOSTRIDIUM DIFFICILE; TOXB PROTEIN, CLOSTRIDIUM DIFFICILE; TRANSCRIPTION FACTOR; TRANSCRIPTION REPAIR COUPLING FACTOR PROTEIN, BACTERIA;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM CULTURE; BACTERIUM MUTANT; CONTROLLED STUDY; CYTOTOXICITY; GENETIC PROCEDURES; HT 29 CELL LINE; INTRON; MASS SPECTROMETRY; MDF GENE; MORPHOLOGY; NONHUMAN; PEPTOCLOSTRIDIUM DIFFICILE; PLASMID; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; UPREGULATION; VERO CELL LINE; WESTERN BLOTTING; ANIMAL; CELL SURVIVAL; CELL WALL; CHLOROCEBUS AETHIOPS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HT-29 CELL LINE; HUMAN; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CELL SURVIVAL; CELL WALL; CERCOPITHECUS AETHIOPS; CLOSTRIDIUM DIFFICILE; ENTEROTOXINS; GENE EXPRESSION REGULATION, BACTERIAL; HT29 CELLS; HUMANS; MUTAGENESIS, INSERTIONAL; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; UP-REGULATION; VERO CELLS;

EID: 84950271535     PISSN: None     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/s12866-015-0611-5     Document Type: Article

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