-
1
-
-
84877101072
-
Prostate cancer: RSMO Consensus Conference Guidelines 2012
-
Horwich A, Hugosson J, de Reijke T et al. Prostate cancer: RSMO Consensus Conference Guidelines 2012. Ann. Oncol. 24, 1141-1162 (2013).
-
(2013)
Ann. Oncol.
, vol.24
, pp. 1141-1162
-
-
Horwich, A.1
Hugosson, J.2
De Reijke, T.3
-
2
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff PW, Higano CS, Shore ND et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N. Engl. J. Med. 363, 411-422 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
-
3
-
-
77957682309
-
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomized open-label trial
-
de Bono JS, Oudard S, Ozguroglu M et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomized open-label trial. Lancet. 376, 1147-1154 (2010).
-
(2010)
Lancet.
, vol.376
, pp. 1147-1154
-
-
De Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
-
4
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
de Bono JS, Logothetis CJ, Molina A et al. Abiraterone and increased survival in metastatic prostate cancer. N. Engl. J. Med. 364, 1995-2005 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 1995-2005
-
-
De Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
-
5
-
-
84866770294
-
Increased survival with enzalutamide in prostate cancer after chemotherapy
-
Scher HI, Fizazi K, Saad F et al. Increased survival with enzalutamide in prostate cancer after chemotherapy. N. Engl. J. Med. 367, 1187-1197 (2012).
-
(2012)
N. Engl. J. Med.
, vol.367
, pp. 1187-1197
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
-
6
-
-
84880428467
-
Alpha emitter radium-223 and survival in metastatic prostate cancer
-
Parker C, Nilsson S, Heinrich D et al. Alpha emitter radium-223 and survival in metastatic prostate cancer. N. Engl. J. Med. 369, 213-223 (2013).
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 213-223
-
-
Parker, C.1
Nilsson, S.2
Heinrich, D.3
-
7
-
-
84921731019
-
Therapeutic vaccines as a promising treatment modality against prostate cancer: Rationale and recent advances
-
Singh BH, Gulley JL. Therapeutic vaccines as a promising treatment modality against prostate cancer: rationale and recent advances. Thr. Adv. Vaccines. 2, 137-148 (2014).
-
(2014)
Thr. Adv. Vaccines.
, vol.2
, pp. 137-148
-
-
Singh, B.H.1
Gulley, J.L.2
-
8
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 144, 646-674 (2011).
-
(2011)
Cell.
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
9
-
-
70349485580
-
Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+
-
Sfanos KS, Bruno RC, Meeker AK, De Marzo AM, Isaacs WB, Drake CG. Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+. Prostate. 69, 1694-1703 (2009).
-
(2009)
Prostate.
, vol.69
, pp. 1694-1703
-
-
Sfanos, K.S.1
Bruno, R.C.2
Meeker, A.K.3
De Marzo, A.M.4
Isaacs, W.B.5
Drake, C.G.6
-
10
-
-
33846434093
-
The terminology issue for myeloid-derived suppressor cells
-
Gabrilovich DI, Bronte V, Chen SH et al. The terminology issue for myeloid-derived suppressor cells. Cancer Res. 67, 425 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 425
-
-
Gabrilovich, D.I.1
Bronte, V.2
Chen, S.H.3
-
11
-
-
84862243575
-
Current and emerging treatment options for castration-resistant prostate cancer: A focus on immunotherapy
-
Genitsen WR, Sharma P. Current and emerging treatment options for castration-resistant prostate cancer: a focus on immunotherapy. J. Clin. Immunol. 32, 25-35 (2012).
-
(2012)
J. Clin. Immunol.
, vol.32
, pp. 25-35
-
-
Genitsen, W.R.1
Sharma, P.2
-
13
-
-
84866242667
-
IDO is a nodal pathogenic driver of lung cancer and metastasis development
-
Smith C, Chang MY, Parker KH et al. IDO is a nodal pathogenic driver of lung cancer and metastasis development. Cancer Discov. 2, 722-735 (2012).
-
(2012)
Cancer Discov.
, vol.2
, pp. 722-735
-
-
Smith, C.1
Chang, M.Y.2
Parker, K.H.3
-
14
-
-
68749087029
-
Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients
-
Gannon PO, Poisson AO, Delvoye N, Lapointe R, Mes-Masson AM, Saad F. Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients. J. Immunol. Methods. 348, 9-17 (2009).
-
(2009)
J. Immunol. Methods.
, vol.348
, pp. 9-17
-
-
Gannon, P.O.1
Poisson, A.O.2
Delvoye, N.3
Lapointe, R.4
Mes-Masson, A.M.5
Saad, F.6
-
15
-
-
80051682043
-
Prostate cancer immunotherapy
-
May KF Jr, Gulley JL, Drake CG, Dranoff G, Kantoff PW. Prostate cancer immunotherapy. Clin. Cancer Res. 17, 5233-5238 (2011).
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 5233-5238
-
-
May, Jr.K.F.1
Gulley, J.L.2
Drake, C.G.3
Dranoff, G.4
Kantoff, P.W.5
-
16
-
-
84892620328
-
Is there a role for immune checkpoint blockade with ipilimumab in prostate cancer
-
Cha E, Small EJ. Is there a role for immune checkpoint blockade with ipilimumab in prostate cancer Cancer Med. 2, 243-252 (2013).
-
(2013)
Cancer Med.
, vol.2
, pp. 243-252
-
-
Cha, E.1
Small, E.J.2
-
18
-
-
0036083073
-
Technology evaluation: APC-8015 Dendreon
-
Rini BI. Technology evaluation: APC-8015, Dendreon. Curr. Opin. Mol. Ther. 4, 76-79 (2002).
-
(2002)
Curr. Opin. Mol. Ther.
, vol.4
, pp. 76-79
-
-
Rini, B.I.1
-
19
-
-
0034554863
-
Immunotherapy of Hormone-Refractory prostate cancer with antigen-loaded dendritic cells
-
Small E, Fratesi P, Reese D et al. Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells. J. Clin. Oncol. 18, 3894-3903 (2000).
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 3894-3903
-
-
Small, E.1
Fratesi, P.2
Reese, D.3
-
20
-
-
0034043167
-
Priming tissue-specific cellular immunity in a Phase i trial of autologous dendritic cells for prostate cancer
-
Burch PA, Breen JK, Buckner JC et al. Priming tissue-specific cellular immunity in a Phase I trial of autologous dendritic cells for prostate cancer. Clin. Cancer Res. 6, 2175-2182 (2000).
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2175-2182
-
-
Burch, P.A.1
Breen, J.K.2
Buckner, J.C.3
-
21
-
-
34249692904
-
Immunological evaluation of neoadjuvant peptide vaccination before radical prostatectomy for patients with localized prostate cancer
-
Noguchi M, Yao A, Harada M et al. Immunological evaluation of neoadjuvant peptide vaccination before radical prostatectomy for patients with localized prostate cancer. Prostate 67, 933-942 (2007).
-
(2007)
Prostate
, vol.67
, pp. 933-942
-
-
Noguchi, M.1
Yao, A.2
Harada, M.3
-
22
-
-
84878601468
-
Lower baseline prostate-specific antigen is associated with a greater overall survival benefit from sipuleucel-T in the immunotherapy for prostate adenocarcinoma treatment (IMPACT) trial
-
Schellhammer PF, Chodak G, Whitmore JB et al. Lower baseline prostate-specific antigen is associated with a greater overall survival benefit from sipuleucel-T in the immunotherapy for prostate adenocarcinoma treatment (IMPACT) trial. Urology. 81, 1297-1302 (2013).
-
(2013)
Urology.
, vol.81
, pp. 1297-1302
-
-
Schellhammer, P.F.1
Chodak, G.2
Whitmore, J.B.3
-
23
-
-
0041909467
-
Induction of cellular and humoral immune responses to tumor cells and peptides in HLA-A24 positive hormone-refractory prostate cancer patients by peptide vaccination
-
Noguchi M, Kobayashi K, Suetsugu N et al. Induction of cellular and humoral immune responses to tumor cells and peptides in HLA-A24 positive hormone-refractory prostate cancer patients by peptide vaccination. Prostate. 57, 80-92 (2003).
-
(2003)
Prostate.
, vol.57
, pp. 80-92
-
-
Noguchi, M.1
Kobayashi, K.2
Suetsugu, N.3
-
24
-
-
1142275255
-
Phase i trial of patient-oriented vaccination in HLA-A2 positive patients with metastatic hormone refractory prostate cancer
-
Noguchi M, Itoh K, Suekane S et al. Phase I trial of patient-oriented vaccination in HLA-A2 positive patients with metastatic hormone refractory prostate cancer. Cancer Sci. 95, 77-84 (2004).
-
(2004)
Cancer Sci.
, vol.95
, pp. 77-84
-
-
Noguchi, M.1
Itoh, K.2
Suekane, S.3
-
25
-
-
38049048619
-
Sipuleucel-T: A vaccine for metastatic, asymptomatic, androgen-independent prostate cancer
-
Patel PH, Kockler DR. Sipuleucel-T: a vaccine for metastatic, asymptomatic, androgen-independent prostate cancer. Ann. Pharmacother. 42, 91-98 (2008).
-
(2008)
Ann. Pharmacother.
, vol.42
, pp. 91-98
-
-
Patel, P.H.1
Kockler, D.R.2
-
26
-
-
33746012881
-
Placebocontrolled Phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer
-
Small EJ, Schellhammer PF, Higano CS et al. Placebocontrolled Phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer. J. Clin. Oncol. 24, 3089-3094 (2006).
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 3089-3094
-
-
Small, E.J.1
Schellhammer, P.F.2
Higano, C.S.3
-
27
-
-
68549135290
-
Integrated data from 2 randomized, double-blind, placebo-controlled Phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
-
Higano CS, Schellhammer PF, Small EJ et al. Integrated data from 2 randomized, double-blind, placebo-controlled Phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer. 115, 3670-3679 (2009).
-
(2009)
Cancer.
, vol.115
, pp. 3670-3679
-
-
Higano, C.S.1
Schellhammer, P.F.2
Small, E.J.3
-
28
-
-
84872601546
-
Immune responses in prostate tumor tissue following neoadjuvant sipuleucel-T in patients with localized prostate cancer
-
Fong L, Weinberg VK, Corman JM et al. Immune responses in prostate tumor tissue following neoadjuvant sipuleucel-T in patients with localized prostate cancer. J. Clin. Oncol. 30(Suppl. 5), Abstract 181 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
-
-
Fong, L.1
Weinberg, V.K.2
Corman, J.M.3
-
29
-
-
52049090425
-
Phase 1/2 doseescalation study of a GM-CSF-secreting, allogeneic, cellular immunotherapy for metastatic hormone-refractory prostate cancer
-
Higano CS, Corman JM, Smith DC et al. Phase 1/2 doseescalation study of a GM-CSF-secreting, allogeneic, cellular immunotherapy for metastatic hormone-refractory prostate cancer. Cancer. 113, 975-984 (2008).
-
(2008)
Cancer.
, vol.113
, pp. 975-984
-
-
Higano, C.S.1
Corman, J.M.2
Smith, D.C.3
-
30
-
-
84862243575
-
Current and emerging treatment options for castration-resistant prostate cancer: A focus on immunotherapy
-
Gerristen WR, Sharma P. Current and emerging treatment options for castration-resistant prostate cancer: a focus on immunotherapy. J. Clin. Immunol. 32, 25-35 (2012).
-
(2012)
J. Clin. Immunol.
, vol.32
, pp. 25-35
-
-
Gerristen, W.R.1
Sharma, P.2
-
31
-
-
70349926513
-
A Phase III trial of GVAX immunotherapy for prostate cancer in combination with docetaxel vs docetaxel plus prednisone in symptomatic, castration resistant prostate cancer (CRPC)
-
Small E, Demknow T, Gerritsen W et al. A Phase III trial of GVAX immunotherapy for prostate cancer in combination with docetaxel vs docetaxel plus prednisone in symptomatic, castration resistant prostate cancer (CRPC). Proc. Am. Soc. Clin. Oncol. Genitourinary Cancer Symposium(Abstract 7) (2009).
-
(2009)
Proc. Am. Soc. Clin. Oncol. Genitourinary Cancer Symposium
-
-
Small, E.1
Demknow, T.2
Gerritsen, W.3
-
32
-
-
84860436621
-
Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: A Phase i dose escalation trial
-
van den Ecrtwegh AJ, Versluis J, van den Berg HP et al. Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: a Phase I dose escalation trial. Lancet Oncol. 13, 509-517 (2012).
-
(2012)
Lancet Oncol.
, vol.13
, pp. 509-517
-
-
Vanden Ecrtwegh, A.J.1
Versluis, J.2
Van Den Berg, H.P.3
-
33
-
-
67650463335
-
Prostavac-VF: A vector-based vaccine targeting PSA in prostate cancer
-
Madan RA, Arlen PM, Mohebtash M et al. Prostavac-VF: a vector-based vaccine targeting PSA in prostate cancer. Expert Opin. Investig. Drugs. 18, 1001-1011 (2009).
-
(2009)
Expert Opin. Investig. Drugs.
, vol.18
, pp. 1001-1011
-
-
Madan, R.A.1
Arlen, P.M.2
Mohebtash, M.3
-
34
-
-
34548452131
-
Clinical safety of a viral vector-based prostate cancer vaccine strategy
-
Arlen PM, Skarupa L, Pazdur M et al. Clinical safety of a viral vector-based prostate cancer vaccine strategy. J. Urol. 178, 1515-1520 (2007).
-
(2007)
J. Urol.
, vol.178
, pp. 1515-1520
-
-
Arlen, P.M.1
Skarupa, L.2
Pazdur, M.3
-
35
-
-
17444440950
-
A Phase i trial of a recombinant vaccina virus expressing prostate-specific antigen in advanced prostate cancer
-
Eder JP, Kantoff PW, Roper K et al. A Phase I trial of a recombinant vaccina virus expressing prostate-specific antigen in advanced prostate cancer. Clin. Cancer Res. 6, 1632-1638 (2000).
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1632-1638
-
-
Eder, J.P.1
Kantoff, P.W.2
Roper, K.3
-
36
-
-
0034551730
-
Phase i study in advanced cancer patients of a diversified prime-andboost vaccination protocol using recombinant vaccina virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses
-
Marchall JL, Hoyer RJ, Toomey MA et al. Phase I study in advanced cancer patients of a diversified prime-andboost vaccination protocol using recombinant vaccina virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses. J. Clin. Oncol. 18, 3964-3973 (2000).
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 3964-3973
-
-
Marchall, J.L.1
Hoyer, R.J.2
Toomey, M.A.3
-
37
-
-
0036787490
-
Phase i study of a vaccine using recombinant vaccina virus expressing PSA (rV-PSA) in patients with metastatic androgen-independent prostate cancer
-
Gulley J, Chen AP, Dahut W et al. Phase I study of a vaccine using recombinant vaccina virus expressing PSA (rV-PSA) in patients with metastatic androgen-independent prostate cancer. Prostate. 53, 109-117 (2002).
-
(2002)
Prostate.
, vol.53
, pp. 109-117
-
-
Gulley, J.1
Chen, A.P.2
Dahut, W.3
-
38
-
-
77949895922
-
Overall survival analysis of a Phase II randomized controlled trial of Poxviralbased PSA-targeted immunotherapy in metastatic castrationresistant prostate cancer
-
Kantoff PW, Schuetz TJ, Blumenstein BA et al. Overall survival analysis of a Phase II randomized controlled trial of Poxviralbased PSA-targeted immunotherapy in metastatic castrationresistant prostate cancer. J. Clin. Oncol. 28, 1099-1105 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 1099-1105
-
-
Kantoff, P.W.1
Schuetz, T.J.2
Blumenstein, B.A.3
-
39
-
-
84877815818
-
Personalized peptide vaccination: A new approach for advanced cancer as therapeutic cancer vaccine
-
Noguchi M, Sasada T, Itoh K. Personalized peptide vaccination: a new approach for advanced cancer as therapeutic cancer vaccine. Cancer Immunol. Immunother. 62, 919-929 (2013).
-
(2013)
Cancer Immunol. Immunother.
, vol.62
, pp. 919-929
-
-
Noguchi, M.1
Sasada, T.2
Itoh, K.3
-
40
-
-
79951530554
-
A Phase i study of personalized peptide vaccination using 14 kinds of vaccine in combination with low-dose estramustine in HLA-A24-positive patients with castration-resistant prostate cancer
-
Noguchi M, Uemura H, Naito S, Akaza H, Yamada A, Itoh K. A Phase I study of personalized peptide vaccination using 14 kinds of vaccine in combination with low-dose estramustine in HLA-A24-positive patients with castration-resistant prostate cancer. Prostate. 71, 470-479 (2011).
-
(2011)
Prostate.
, vol.71
, pp. 470-479
-
-
Noguchi, M.1
Uemura, H.2
Naito, S.3
Akaza, H.4
Yamada, A.5
Itoh, K.6
-
41
-
-
77953040440
-
A randomized Phase II trial of personalized peptide vaccine plus low dose estramustine phosphate (EMP) versus standard dose EMP in patients with castration resistant prostate cancer
-
Noguchi M, Kakuma T, Uemura H et al. A randomized Phase II trial of personalized peptide vaccine plus low dose estramustine phosphate (EMP) versus standard dose EMP in patients with castration resistant prostate cancer. Cancer Immunol. Immunother. 59, 1001-1009 (2010).
-
(2010)
Cancer Immunol. Immunother.
, vol.59
, pp. 1001-1009
-
-
Noguchi, M.1
Kakuma, T.2
Uemura, H.3
-
42
-
-
84860347746
-
Phase II study of personalized peptide vaccination for castration-resistant prostate cancer patients who failed in docetaxel-based chemotherapy
-
Noguchi M, Moriya F, Suekane S et al. Phase II study of personalized peptide vaccination for castration-resistant prostate cancer patients who failed in docetaxel-based chemotherapy. Prostate. 72, 834-845 (2012).
-
(2012)
Prostate.
, vol.72
, pp. 834-845
-
-
Noguchi, M.1
Moriya, F.2
Suekane, S.3
-
43
-
-
70249126960
-
Safety and immunological efficacy of a DNA vaccine encoding prostate acid phosphatase in patients with stage D0 prostate cancer
-
McNeel DG, Dunphy EJ, Davies JG et al. Safety and immunological efficacy of a DNA vaccine encoding prostate acid phosphatase in patients with stage D0 prostate cancer. J. Clin. Oncol. 27, 4047-4054 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 4047-4054
-
-
McNeel, D.G.1
Dunphy, E.J.2
Davies, J.G.3
-
44
-
-
77954951895
-
DNA vaccine encoding prostatic acid phosphatase (PAP) elicits long-term T-cell responses in patients with recurrent prostate cancer
-
Becker JT, Olson BM, Johnson LE, Davies JG, Dunphy EJ, McNeel DG. DNA vaccine encoding prostatic acid phosphatase (PAP) elicits long-term T-cell responses in patients with recurrent prostate cancer. J. Immunother. 33, 639-647 (2010).
-
(2010)
J. Immunother.
, vol.33
, pp. 639-647
-
-
Becker, J.T.1
Olson, B.M.2
Johnson, L.E.3
Davies, J.G.4
Dunphy, E.J.5
McNeel, D.G.6
-
45
-
-
84856867834
-
Immunotherapy earns its spot in the ranks of cancer therapy
-
Pardoll D, Drake C. Immunotherapy earns its spot in the ranks of cancer therapy. J. Exp. Med. 209, 201-209 (2012).
-
(2012)
J. Exp. Med.
, vol.209
, pp. 201-209
-
-
Pardoll, D.1
Drake, C.2
-
46
-
-
84880508629
-
Ipilimumab alone or in combination with radiotherapy in metastatic castrationresistant prostate cancer: Results from an open-label, multicenter Phase I/II study
-
Slovin SF, Higano CS, Hamid O et al. Ipilimumab alone or in combination with radiotherapy in metastatic castrationresistant prostate cancer: results from an open-label, multicenter Phase I/II study. Ann. Oncol. 24, 1813-1821 (2013).
-
(2013)
Ann. Oncol.
, vol.24
, pp. 1813-1821
-
-
Slovin, S.F.1
Higano, C.S.2
Hamid, O.3
-
47
-
-
84901641673
-
Ipilimumab versus placebo after radiotherapy in patients with metastatic castrationresistant prostate cancer that had progressed after docetaxel chemotherapy (CA 184-043): A multicentre, randomized, double-blind, Phase 3 trial
-
Kwon ED, Drake CG, Scher HI et al. Ipilimumab versus placebo after radiotherapy in patients with metastatic castrationresistant prostate cancer that had progressed after docetaxel chemotherapy (CA 184-043): a multicentre, randomized, double-blind, Phase 3 trial. Lancet Oncol.15, 700-712 (2014).
-
(2014)
Lancet Oncol
, vol.15
, pp. 700-712
-
-
Kwon, E.D.1
Drake, C.G.2
Scher, H.I.3
-
48
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi PS, Brahmer JR et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 366, 2443-2454 (2012).
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, P.S.2
Brahmer, J.R.3
-
49
-
-
77954899030
-
Phase i study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer JR, Drake CG, Wollner I et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J. Clin. Oncol. 28, 3167-3175 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
-
50
-
-
84950283228
-
PD-1 or PD-L1 blockade restores antitumor efficacy following SSX2 epitope-modified DNA vaccine immunization
-
Rekoske BT, Smith HA, Olson BM, Maricque BB, McNeel DG. PD-1 or PD-L1 blockade restores antitumor efficacy following SSX2 epitope-modified DNA vaccine immunization. Cancer Immunol. Res. 3, 1-10 (2015).
-
(2015)
Cancer Immunol. Res.
, vol.3
, pp. 1-10
-
-
Rekoske, B.T.1
Smith, H.A.2
Olson, B.M.3
Maricque, B.B.4
McNeel, D.G.5
-
51
-
-
41949104346
-
Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group
-
Scher HI, Halabi S, Tannock I et al. Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group. J. Clin. Oncol. 26, 1148-1159 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 1148-1159
-
-
Scher, H.I.1
Halabi, S.2
Tannock, I.3
-
52
-
-
79953816808
-
Immunologic biomarkers as correlates of clinical response to cancer immunotherapy
-
Disis ML. Immunologic biomarkers as correlates of clinical response to cancer immunotherapy. Cancer Immunol. Immunother. 60, 433-442 (2011).
-
(2011)
Cancer Immunol. Immunother.
, vol.60
, pp. 433-442
-
-
Disis, M.L.1
-
53
-
-
78650348177
-
Assessment of immunological biomarkers in patients with advanced cancer treated by personalized peptide vaccination
-
Noguchi M, Mine T, Komatsu N et al. Assessment of immunological biomarkers in patients with advanced cancer treated by personalized peptide vaccination. Cancer Biol. Ther. 12, 1266-1279 (2011).
-
(2011)
Cancer Biol. Ther.
, vol.12
, pp. 1266-1279
-
-
Noguchi, M.1
Mine, T.2
Komatsu, N.3
-
54
-
-
77957273591
-
Improved endpoints for cancer immunotherapy trials
-
Hoos A, Eggermont AM, Janetzki S et al. Improved endpoints for cancer immunotherapy trials. J. Natl Cancer Inst. 102, 1388-1397 (2010).
-
(2010)
J. Natl Cancer Inst.
, vol.102
, pp. 1388-1397
-
-
Hoos, A.1
Eggermont, A.M.2
Janetzki, S.3
-
55
-
-
79960657821
-
Autoimmunity associated with immunotherapy of cancer
-
Amos SM, Duong CP, Westwood JA et al. Autoimmunity associated with immunotherapy of cancer. Blood. 118, 499-509 (2011).
-
(2011)
Blood.
, vol.118
, pp. 499-509
-
-
Amos, S.M.1
Duong, C.P.2
Westwood, J.A.3
-
56
-
-
60849084473
-
Prolonged survival of dendritic cell-vaccinated melanoma patients correlates with tumor-specific delayed type IV hypersensitivity response and reduction of tumor growth factor beta-expressing T cells
-
López MN, Pereda C, Segal G et al. Prolonged survival of dendritic cell-vaccinated melanoma patients correlates with tumor-specific delayed type IV hypersensitivity response and reduction of tumor growth factor beta-expressing T cells. J. Clin. Oncol. 27, 945-952 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 945-952
-
-
López, M.N.1
Pereda, C.2
Segal, G.3
-
57
-
-
84872488155
-
Sipuleucel-T immune parameters correlate with survival: An analysis of the randomized Phase 3 clinical trials in men with castrationresistant prostate cancer
-
Sheikh NA, Petrylak D, Kantoff PW et al. Sipuleucel-T immune parameters correlate with survival: an analysis of the randomized Phase 3 clinical trials in men with castrationresistant prostate cancer. Cancer Immunol. Immunother. 62, 137-147 (2013).
-
(2013)
Cancer Immunol. Immunother.
, vol.62
, pp. 137-147
-
-
Sheikh, N.A.1
Petrylak, D.2
Kantoff, P.W.3
-
58
-
-
84874116175
-
T cell profiling reveals high CD4+CTLA-4 + T cell frequency as dominant predictor for survival after prostate GVAX/ipilimumab treatment
-
Santegoets SJ, Stam AG, Lougheed SM et al. T cell profiling reveals high CD4+CTLA-4 + T cell frequency as dominant predictor for survival after prostate GVAX/ipilimumab treatment. Cancer Immunol. Immunother. 62, 245-256 (2013).
-
(2013)
Cancer Immunol. Immunother.
, vol.62
, pp. 245-256
-
-
Santegoets, S.J.1
Stam, A.G.2
Lougheed, S.M.3
|