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Volumn 64, Issue 4, 2015, Pages 401-408

Prostate cancer vaccines: the long road to clinical application

Author keywords

Biomarkers; Cancer vaccines; Cross presentation; Epitope spreading; Immunomodulation; Prostate cancer

Indexed keywords

BIOLOGICAL MARKER; CANCER VACCINE; EPITOPE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR VACCINE; HLA A24 ANTIGEN; HLA DR11 ANTIGEN; INTERLEUKIN 12; IPILIMUMAB; NIVOLUMAB; PROSTATE SPECIFIC ANTIGEN;

EID: 84925498921     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-015-1667-7     Document Type: Review
Times cited : (21)

References (50)
  • 1
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: integrating immunity’s roles in cancer suppression and promotion
    • COI: 1:CAS:528:DC%2BC3MXjs1Cgtbs%3D, PID: 21436444
    • Schreiber RD, Old LJ, Smyth MJ (2011) Cancer immunoediting: integrating immunity’s roles in cancer suppression and promotion. Science 331:1565–1570. doi:10.1126/science.1203486
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 2
    • 79959302198 scopus 로고    scopus 로고
    • Impact of tumour volume on the potential efficacy of therapeutic vaccines
    • COI: 1:STN:280:DC%2BC3MrovVequg%3D%3D, PID: 21655153
    • Gulley JL, Madan RA, Schlom J (2011) Impact of tumour volume on the potential efficacy of therapeutic vaccines. Curr Oncol 18:e150–e157
    • (2011) Curr Oncol , vol.18 , pp. e150-e157
    • Gulley, J.L.1    Madan, R.A.2    Schlom, J.3
  • 3
    • 84921731019 scopus 로고    scopus 로고
    • Therapeutic vaccines as a promising treatment modality against prostate cancer: rationale and recent advances
    • COI: 1:CAS:528:DC%2BC2cXhvFKnsbzI, PID: 25177493
    • Singh BH, Gulley JL (2014) Therapeutic vaccines as a promising treatment modality against prostate cancer: rationale and recent advances. Ther Adv Vaccines 2:137–148. doi:10.1177/2051013614539478
    • (2014) Ther Adv Vaccines , vol.2 , pp. 137-148
    • Singh, B.H.1    Gulley, J.L.2
  • 4
    • 84856710029 scopus 로고    scopus 로고
    • Endpoints, patient selection, and biomarkers in the design of clinical trials for cancer vaccines
    • PID: 22120693
    • Bilusic M, Gulley JL (2012) Endpoints, patient selection, and biomarkers in the design of clinical trials for cancer vaccines. Cancer Immunol Immunother 61:109–117. doi:10.1007/s00262-011-1141-0
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 109-117
    • Bilusic, M.1    Gulley, J.L.2
  • 5
    • 84859877124 scopus 로고    scopus 로고
    • Combining immunological and androgen-directed approaches: an emerging concept in prostate cancer immunotherapy
    • COI: 1:CAS:528:DC%2BC38Xls1SltL0%3D, PID: 22410456
    • Antonarakis ES, Drake CG (2012) Combining immunological and androgen-directed approaches: an emerging concept in prostate cancer immunotherapy. Curr Opin Oncol 24:258–265. doi:10.1097/CCO.0b013e32835205a0
    • (2012) Curr Opin Oncol , vol.24 , pp. 258-265
    • Antonarakis, E.S.1    Drake, C.G.2
  • 6
    • 37549032137 scopus 로고    scopus 로고
    • Immunological aspects of cancer chemotherapy
    • COI: 1:CAS:528:DC%2BD2sXhsVKrsLnP, PID: 18097448
    • Zitvogel L, Apetoh L, Ghiringhelli F, Kroemer G (2008) Immunological aspects of cancer chemotherapy. Nat Rev Immunol 8:59–73. doi:10.1038/nri2216
    • (2008) Nat Rev Immunol , vol.8 , pp. 59-73
    • Zitvogel, L.1    Apetoh, L.2    Ghiringhelli, F.3    Kroemer, G.4
  • 7
    • 84921298733 scopus 로고    scopus 로고
    • Immune-checkpoint inhibitors march on, now in combinations
    • COI: 1:CAS:528:DC%2BC2cXmtlWrsb0%3D, PID: 24714455
    • Sheridan C (2014) Immune-checkpoint inhibitors march on, now in combinations. Nat Biotechnol 32:297–299. doi:10.1038/nbt0414-297
    • (2014) Nat Biotechnol , vol.32 , pp. 297-299
    • Sheridan, C.1
  • 8
    • 84896489380 scopus 로고    scopus 로고
    • A combination trial of vaccine plus ipilimumab in metastatic castration-resistant prostate cancer patients: immune correlates
    • COI: 1:CAS:528:DC%2BC2cXis1SisL4%3D, PID: 24514956
    • Jochems C, Tucker JA, Tsang KY, Madan RA, Dahut WL, Liewehr DJ, Steinberg SM, Gulley JL, Schlom J (2014) A combination trial of vaccine plus ipilimumab in metastatic castration-resistant prostate cancer patients: immune correlates. Cancer Immunol Immunother 63:407–418. doi:10.1007/s00262-014-1524-0
    • (2014) Cancer Immunol Immunother , vol.63 , pp. 407-418
    • Jochems, C.1    Tucker, J.A.2    Tsang, K.Y.3    Madan, R.A.4    Dahut, W.L.5    Liewehr, D.J.6    Steinberg, S.M.7    Gulley, J.L.8    Schlom, J.9
  • 9
    • 0033865109 scopus 로고    scopus 로고
    • Driver clones and determinant spreading
    • COI: 1:STN:280:DC%2BD3cvptF2isQ%3D%3D, PID: 10882052
    • Sercarz EE (2000) Driver clones and determinant spreading. J Autoimmun 14:275–277. doi:10.1006/jaut.2000.0380
    • (2000) J Autoimmun , vol.14 , pp. 275-277
    • Sercarz, E.E.1
  • 10
    • 79951826832 scopus 로고    scopus 로고
    • Tumor regression and growth rates determined in five intramural NCI prostate cancer trials: the growth rate constant as an indicator of therapeutic efficacy
    • COI: 1:CAS:528:DC%2BC3MXitVWjsb8%3D, PID: 21106727
    • Stein WD, Gulley JL, Schlom J et al (2011) Tumor regression and growth rates determined in five intramural NCI prostate cancer trials: the growth rate constant as an indicator of therapeutic efficacy. Clin Cancer Res 17:907–917. doi:10.1158/1078-0432.CCR-10-1762
    • (2011) Clin Cancer Res , vol.17 , pp. 907-917
    • Stein, W.D.1    Gulley, J.L.2    Schlom, J.3
  • 12
    • 84860188105 scopus 로고    scopus 로고
    • Therapeutic cancer vaccines: current status and moving forward
    • COI: 1:CAS:528:DC%2BC38Xmt1Shur8%3D, PID: 22395641
    • Schlom J (2012) Therapeutic cancer vaccines: current status and moving forward. J Natl Cancer Inst 104:599–613. doi:10.1093/jnci/djs033
    • (2012) J Natl Cancer Inst , vol.104 , pp. 599-613
    • Schlom, J.1
  • 13
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • COI: 1:CAS:528:DC%2BC3cXhtVGlurrN, PID: 20818862
    • Kantoff PW, Higano CS, Shore ND et al (2010) Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 363:411–422. doi:10.1056/NEJMoa1001294
    • (2010) N Engl J Med , vol.363 , pp. 411-422
    • Kantoff, P.W.1    Higano, C.S.2    Shore, N.D.3
  • 14
    • 77957273591 scopus 로고    scopus 로고
    • Improved endpoints for cancer immunotherapy trials
    • COI: 1:CAS:528:DC%2BC3cXht1WhsL%2FI, PID: 20826737
    • Hoos A, Eggermont AM, Janetzki S et al (2010) Improved endpoints for cancer immunotherapy trials. J Natl Cancer Inst 102:1388–1397. doi:10.1093/jnci/djq310
    • (2010) J Natl Cancer Inst , vol.102 , pp. 1388-1397
    • Hoos, A.1    Eggermont, A.M.2    Janetzki, S.3
  • 15
    • 84865630094 scopus 로고    scopus 로고
    • Increasing the efficacy of tumor cell vaccines by enhancing cross priming
    • COI: 1:CAS:528:DC%2BC38XhtFeit7bL, PID: 22809568
    • Andersen BM, Ohlfest JR (2012) Increasing the efficacy of tumor cell vaccines by enhancing cross priming. Cancer Lett 325:155–164. doi:10.1016/j.canlet.2012.07.012
    • (2012) Cancer Lett , vol.325 , pp. 155-164
    • Andersen, B.M.1    Ohlfest, J.R.2
  • 16
    • 77952839416 scopus 로고    scopus 로고
    • CD8alpha+ DC are not the sole subset cross-presenting cell-associated tumor antigens from a solid tumor
    • COI: 1:CAS:528:DC%2BC3cXnsVWgsLo%3D, PID: 20373290
    • McDonnell AM, Prosser AC, van Bruggen I, Robinson BW, Currie AJ (2010) CD8alpha+ DC are not the sole subset cross-presenting cell-associated tumor antigens from a solid tumor. Eur J Immunol 40:1617–1627. doi:10.1002/eji.200940153
    • (2010) Eur J Immunol , vol.40 , pp. 1617-1627
    • McDonnell, A.M.1    Prosser, A.C.2    van Bruggen, I.3    Robinson, B.W.4    Currie, A.J.5
  • 17
    • 0037811736 scopus 로고    scopus 로고
    • Immunization with Melan-A peptide-pulsed peripheral blood mononuclear cells plus recombinant human interleukin-12 induces clinical activity and T-cell responses in advanced melanoma
    • COI: 1:CAS:528:DC%2BD2cXpsVKjs7g%3D, PID: 12805336
    • Peterson AC, Harlin H, Gajewski TF (2003) Immunization with Melan-A peptide-pulsed peripheral blood mononuclear cells plus recombinant human interleukin-12 induces clinical activity and T-cell responses in advanced melanoma. J Clin Oncol 21:2342–2348. doi:10.1200/JCO.2003.12.144
    • (2003) J Clin Oncol , vol.21 , pp. 2342-2348
    • Peterson, A.C.1    Harlin, H.2    Gajewski, T.F.3
  • 18
    • 0036481263 scopus 로고    scopus 로고
    • Epitope spreading in immune-mediated diseases: implications for immunotherapy
    • COI: 1:CAS:528:DC%2BD38XitFSnu7w%3D, PID: 11910899
    • Vanderlugt CL, Miller SD (2002) Epitope spreading in immune-mediated diseases: implications for immunotherapy. Nat Rev Immunol 2:85–95. doi:10.1038/nri724
    • (2002) Nat Rev Immunol , vol.2 , pp. 85-95
    • Vanderlugt, C.L.1    Miller, S.D.2
  • 19
    • 79953816808 scopus 로고    scopus 로고
    • Immunologic biomarkers as correlates of clinical response to cancer immunotherapy
    • COI: 1:CAS:528:DC%2BC3MXit1Gqsb4%3D, PID: 21221967
    • Disis ML (2011) Immunologic biomarkers as correlates of clinical response to cancer immunotherapy. Cancer Immunol Immunother 60:433–442. doi:10.1007/s00262-010-0960-8
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 433-442
    • Disis, M.L.1
  • 20
    • 20944441967 scopus 로고    scopus 로고
    • Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer
    • COI: 1:CAS:528:DC%2BD2MXjslOqtrc%3D, PID: 15867235
    • Gulley JL, Arlen PM, Bastian A et al (2005) Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer. Clin Cancer Res 11:3353–3362. doi:10.1158/1078-0432.CCR-04-2062
    • (2005) Clin Cancer Res , vol.11 , pp. 3353-3362
    • Gulley, J.L.1    Arlen, P.M.2    Bastian, A.3
  • 21
    • 52649182085 scopus 로고    scopus 로고
    • Safety and immunologic response of a viral vaccine to prostate-specific antigen in combination with radiation therapy when metronomic-dose interleukin 2 is used as an adjuvant
    • COI: 1:CAS:528:DC%2BD1cXpslKns7g%3D, PID: 18698048
    • Lechleider RJ, Arlen PM, Tsang KY et al (2008) Safety and immunologic response of a viral vaccine to prostate-specific antigen in combination with radiation therapy when metronomic-dose interleukin 2 is used as an adjuvant. Clin Cancer Res 14:5284–5291. doi:10.1158/1078-0432.CCR-07-5162
    • (2008) Clin Cancer Res , vol.14 , pp. 5284-5291
    • Lechleider, R.J.1    Arlen, P.M.2    Tsang, K.Y.3
  • 22
    • 84860455345 scopus 로고    scopus 로고
    • Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial
    • COI: 1:CAS:528:DC%2BC38Xmslyhsb0%3D, PID: 22326924
    • Madan RA, Mohebtash M, Arlen PM et al (2012) Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial. Lancet Oncol 13:501–508. doi:10.1016/S1470-2045(12)70006-2
    • (2012) Lancet Oncol , vol.13 , pp. 501-508
    • Madan, R.A.1    Mohebtash, M.2    Arlen, P.M.3
  • 23
    • 33644760431 scopus 로고    scopus 로고
    • A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancer
    • COI: 1:CAS:528:DC%2BD28XhsFaltb8%3D, PID: 16489082
    • Arlen PM, Gulley JL, Parker C et al (2006) A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancer. Clin Cancer Res 12:1260–1269. doi:10.1158/1078-0432.CCR-05-2059
    • (2006) Clin Cancer Res , vol.12 , pp. 1260-1269
    • Arlen, P.M.1    Gulley, J.L.2    Parker, C.3
  • 24
    • 84878016733 scopus 로고    scopus 로고
    • Chemotherapy-induced immunogenic modulation of tumor cells enhances killing by cytotoxic T lymphocytes and is distinct from immunogenic cell death
    • COI: 1:CAS:528:DC%2BC3sXktVKhsL4%3D, PID: 23364915
    • Hodge JW, Garnett CT, Farsaci B, Palena C, Tsang KY, Ferrone S, Gameiro SR (2013) Chemotherapy-induced immunogenic modulation of tumor cells enhances killing by cytotoxic T lymphocytes and is distinct from immunogenic cell death. Int J Cancer 133:624–636. doi:10.1002/ijc.28070
    • (2013) Int J Cancer , vol.133 , pp. 624-636
    • Hodge, J.W.1    Garnett, C.T.2    Farsaci, B.3    Palena, C.4    Tsang, K.Y.5    Ferrone, S.6    Gameiro, S.R.7
  • 25
    • 84875552922 scopus 로고    scopus 로고
    • Immunogenic cell death in cancer therapy
    • COI: 1:CAS:528:DC%2BC3sXnsFClsL8%3D, PID: 23157435
    • Kroemer G, Galluzzi L, Kepp O, Zitvogel L (2013) Immunogenic cell death in cancer therapy. Annu Rev Immunol 31:51–72. doi:10.1146/annurev-immunol-032712-100008
    • (2013) Annu Rev Immunol , vol.31 , pp. 51-72
    • Kroemer, G.1    Galluzzi, L.2    Kepp, O.3    Zitvogel, L.4
  • 26
    • 0033942857 scopus 로고    scopus 로고
    • The immunological effects of taxanes
    • COI: 1:CAS:528:DC%2BD3cXlvFymsb8%3D, PID: 10941900
    • Chan OT, Yang LX (2000) The immunological effects of taxanes. Cancer Immunol Immunother 49:181–185
    • (2000) Cancer Immunol Immunother , vol.49 , pp. 181-185
    • Chan, O.T.1    Yang, L.X.2
  • 27
    • 0035286721 scopus 로고    scopus 로고
    • Enhancement of tumor radioresponse by docetaxel: involvement of immune system
    • COI: 1:CAS:528:DC%2BD3MXhsFGlt7Y%3D, PID: 11179493
    • Mason K, Staab A, Hunter N, McBride W, Petersen S, Terry N, Milas L (2001) Enhancement of tumor radioresponse by docetaxel: involvement of immune system. Int J Oncol 18:599–606
    • (2001) Int J Oncol , vol.18 , pp. 599-606
    • Mason, K.1    Staab, A.2    Hunter, N.3    McBride, W.4    Petersen, S.5    Terry, N.6    Milas, L.7
  • 28
    • 84863556674 scopus 로고    scopus 로고
    • Persistence of immunotherapy survival effects of sipuleucel-T and relationship to postrandomization docetaxel use in phase III studies
    • Petrylak DP, Dawson NA, Gardner T et al (2010) Persistence of immunotherapy survival effects of sipuleucel-T and relationship to postrandomization docetaxel use in phase III studies. J Clin Oncol. 2010 ASCO Annual Meeting Abstracts. 28:4551
    • (2010) J Clin Oncol. 2010 ASCO Annual Meeting Abstracts , vol.28 , pp. 4551
    • Petrylak, D.P.1    Dawson, N.A.2    Gardner, T.3
  • 29
    • 84906089659 scopus 로고    scopus 로고
    • Harnessing the potential of radiation-induced immune modulation for cancer therapy
    • COI: 1:CAS:528:DC%2BC2cXmtFSju7Y%3D, PID: 24777964
    • Ahmed MM, Hodge JW, Guha C, Bernhard EJ, Vikram B, Coleman CN (2013) Harnessing the potential of radiation-induced immune modulation for cancer therapy. Cancer Immunol Res 1:280–284. doi:10.1158/2326-6066.CIR-13-0141
    • (2013) Cancer Immunol Res , vol.1 , pp. 280-284
    • Ahmed, M.M.1    Hodge, J.W.2    Guha, C.3    Bernhard, E.J.4    Vikram, B.5    Coleman, C.N.6
  • 30
    • 84900499259 scopus 로고    scopus 로고
    • Radiation-induced modulation of costimulatory and coinhibitory T-cell signaling molecules on human prostate carcinoma cells promotes productive antitumor immune interactions
    • COI: 1:CAS:528:DC%2BC2cXnvVSms78%3D, PID: 24693958
    • Bernstein MB, Garnett CT, Zhang H, Velcich A, Wattenberg MM, Gameiro SR, Kalnicki S, Hodge JW, Guha C (2014) Radiation-induced modulation of costimulatory and coinhibitory T-cell signaling molecules on human prostate carcinoma cells promotes productive antitumor immune interactions. Cancer Biother Radiopharm 29:153–161. doi:10.1089/cbr.2013.1578
    • (2014) Cancer Biother Radiopharm , vol.29 , pp. 153-161
    • Bernstein, M.B.1    Garnett, C.T.2    Zhang, H.3    Velcich, A.4    Wattenberg, M.M.5    Gameiro, S.R.6    Kalnicki, S.7    Hodge, J.W.8    Guha, C.9
  • 31
    • 84857815877 scopus 로고    scopus 로고
    • Immunologic correlates of the abscopal effect in a patient with melanoma
    • COI: 1:CAS:528:DC%2BC38XktFOgurw%3D, PID: 22397654
    • Postow MA, Callahan MK, Barker CA et al (2012) Immunologic correlates of the abscopal effect in a patient with melanoma. N Engl J Med 366:925–931. doi:10.1056/NEJMoa1112824
    • (2012) N Engl J Med , vol.366 , pp. 925-931
    • Postow, M.A.1    Callahan, M.K.2    Barker, C.A.3
  • 32
    • 3042569675 scopus 로고    scopus 로고
    • External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine-mediated T-cell killing
    • COI: 1:CAS:528:DC%2BD2cXkvFWlsbY%3D, PID: 15205348
    • Chakraborty M, Abrams SI, Coleman CN, Camphausen K, Schlom J, Hodge JW (2004) External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine-mediated T-cell killing. Cancer Res 64:4328–4337. doi:10.1158/0008-5472.CAN-04-0073
    • (2004) Cancer Res , vol.64 , pp. 4328-4337
    • Chakraborty, M.1    Abrams, S.I.2    Coleman, C.N.3    Camphausen, K.4    Schlom, J.5    Hodge, J.W.6
  • 33
    • 84900475271 scopus 로고    scopus 로고
    • Interim analysis of a phase II randomized clinical trial of samrium-153 (Sm-153) with or without PSA-TRICOM vaccine in metastatic castration-resistant prostate cancer after docetaxel
    • Heery CR, Madan RA, Bilusic M et al (2012) Interim analysis of a phase II randomized clinical trial of samrium-153 (Sm-153) with or without PSA-TRICOM vaccine in metastatic castration-resistant prostate cancer after docetaxel. J Clin Oncol. 2012 ASCO Annual Meeting Abstracts. 30:2526
    • (2012) J Clin Oncol. 2012 ASCO Annual Meeting Abstracts. , vol.30 , pp. 2526
    • Heery, C.R.1    Madan, R.A.2    Bilusic, M.3
  • 34
    • 8444230022 scopus 로고    scopus 로고
    • Augmentation of T cell levels and responses induced by androgen deprivation
    • COI: 1:CAS:528:DC%2BD2cXpt1Ols70%3D, PID: 15528346
    • Roden AC, Moser MT, Tri SD et al (2004) Augmentation of T cell levels and responses induced by androgen deprivation. J Immunol 173:6098–6108
    • (2004) J Immunol , vol.173 , pp. 6098-6108
    • Roden, A.C.1    Moser, M.T.2    Tri, S.D.3
  • 35
    • 23444461765 scopus 로고    scopus 로고
    • Activation of thymic regeneration in mice and humans following androgen blockade
    • COI: 1:CAS:528:DC%2BD2MXntVSqsbY%3D, PID: 16081852
    • Sutherland JS, Goldberg GL, Hammett MV et al (2005) Activation of thymic regeneration in mice and humans following androgen blockade. J Immunol 175:2741–2753
    • (2005) J Immunol , vol.175 , pp. 2741-2753
    • Sutherland, J.S.1    Goldberg, G.L.2    Hammett, M.V.3
  • 36
    • 0035807916 scopus 로고    scopus 로고
    • T cell infiltration of the prostate induced by androgen withdrawal in patients with prostate cancer
    • COI: 1:CAS:528:DC%2BD3MXptFCks7g%3D, PID: 11734652
    • Mercader M, Bodner BK, Moser MT et al (2001) T cell infiltration of the prostate induced by androgen withdrawal in patients with prostate cancer. Proc Natl Acad Sci USA 98:14565–14570. doi:10.1073/pnas.251140998
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 14565-14570
    • Mercader, M.1    Bodner, B.K.2    Moser, M.T.3
  • 37
    • 20244380618 scopus 로고    scopus 로고
    • Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen
    • COI: 1:CAS:528:DC%2BD2MXivFCqu74%3D, PID: 15766662
    • Drake CG, Doody AD, Mihalyo MA et al (2005) Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen. Cancer Cell 7:239–249. doi:10.1016/j.ccr.2005.01.027
    • (2005) Cancer Cell , vol.7 , pp. 239-249
    • Drake, C.G.1    Doody, A.D.2    Mihalyo, M.A.3
  • 38
    • 84888113352 scopus 로고    scopus 로고
    • Combination therapy with a second-generation androgen receptor antagonist and a metastasis vaccine improves survival in a spontaneous prostate cancer model
    • COI: 1:CAS:528:DC%2BC3sXhslyku7vJ, PID: 24048332
    • Ardiani A, Farsaci B, Rogers CJ, Protter A, Guo Z, King TH, Apelian D, Hodge JW (2013) Combination therapy with a second-generation androgen receptor antagonist and a metastasis vaccine improves survival in a spontaneous prostate cancer model. Clin Cancer Res 19:6205–6218. doi:10.1158/1078-0432.CCR-13-1026
    • (2013) Clin Cancer Res , vol.19 , pp. 6205-6218
    • Ardiani, A.1    Farsaci, B.2    Rogers, C.J.3    Protter, A.4    Guo, Z.5    King, T.H.6    Apelian, D.7    Hodge, J.W.8
  • 39
    • 84873291815 scopus 로고    scopus 로고
    • Complete biochemical (prostate-specific antigen) response to sipuleucel-T with enzalutamide in castration-resistant prostate cancer: a case report with implications for future research
    • PID: 23374810
    • Graff JN, Drake CG, Beer TM (2013) Complete biochemical (prostate-specific antigen) response to sipuleucel-T with enzalutamide in castration-resistant prostate cancer: a case report with implications for future research. Urology 81:381–383. doi:10.1016/j.urology.2012.10.044
    • (2013) Urology , vol.81 , pp. 381-383
    • Graff, J.N.1    Drake, C.G.2    Beer, T.M.3
  • 41
    • 85018150289 scopus 로고    scopus 로고
    • Lymphoid and myeloid biomarkers for clinical outcome of combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells (GVAX) and ipilimumab in castration-resistant prostate cancer patients
    • van den Eertwegh AJM, de Gruijl T, Santegoets S et al (2012) Lymphoid and myeloid biomarkers for clinical outcome of combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells (GVAX) and ipilimumab in castration-resistant prostate cancer patients. J Clin Oncol. 2012 ASCO Annual Meeting Abstracts. 30:2562
    • (2012) J Clin Oncol. 2012 ASCO Annual Meeting Abstracts. , vol.30 , pp. 2562
    • van den Eertwegh, A.J.M.1    de Gruijl, T.2    Santegoets, S.3
  • 42
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumours: impact on clinical outcome
    • COI: 1:CAS:528:DC%2BC38Xjslersb4%3D, PID: 22419253
    • Fridman WH, Pages F, Sautes-Fridman C, Galon J (2012) The immune contexture in human tumours: impact on clinical outcome. Nat Rev Cancer 12:298–306. doi:10.1038/nrc3245
    • (2012) Nat Rev Cancer , vol.12 , pp. 298-306
    • Fridman, W.H.1    Pages, F.2    Sautes-Fridman, C.3    Galon, J.4
  • 43
    • 84883228590 scopus 로고    scopus 로고
    • Immune responses to cancer: Are they potential biomarkers of prognosis?
    • PID: 23730621
    • Whiteside TL (2013) Immune responses to cancer: Are they potential biomarkers of prognosis? Front Oncol 3:107. doi:10.3389/fonc.2013.00107
    • (2013) Front Oncol , vol.3 , pp. 107
    • Whiteside, T.L.1
  • 44
    • 84864008345 scopus 로고    scopus 로고
    • Functional T cells targeting NY-ESO-1 or Melan-A are predictive for survival of patients with distant melanoma metastasis
    • COI: 1:CAS:528:DC%2BC38XhtVansbfL, PID: 22529253
    • Weide B, Zelba H, Derhovanessian E et al (2012) Functional T cells targeting NY-ESO-1 or Melan-A are predictive for survival of patients with distant melanoma metastasis. J Clin Oncol 30:1835–1841. doi:10.1200/JCO.2011.40.2271
    • (2012) J Clin Oncol , vol.30 , pp. 1835-1841
    • Weide, B.1    Zelba, H.2    Derhovanessian, E.3
  • 45
    • 84924928591 scopus 로고    scopus 로고
    • AE37 peptide vaccination in prostate cancer: identification of biomarkers in the context of prognosis and prediction
    • COI: 1:CAS:528:DC%2BC2cXht1ahtb7F, PID: 25052849
    • Perez SA, Anastasopoulou EA, Papamichail M, Baxevanis CN (2014) AE37 peptide vaccination in prostate cancer: identification of biomarkers in the context of prognosis and prediction. Cancer Immunol Immunother 63:1141–1150. doi:10.1007/s00262-014-1582-3
    • (2014) Cancer Immunol Immunother , vol.63 , pp. 1141-1150
    • Perez, S.A.1    Anastasopoulou, E.A.2    Papamichail, M.3    Baxevanis, C.N.4
  • 47
    • 84902960654 scopus 로고    scopus 로고
    • HLA-A*02 in relation to outcome in human papillomavirus positive tonsillar and base of tongue cancer
    • COI: 1:CAS:528:DC%2BC2cXhtVequ7zP, PID: 24778045
    • Tertipis N, Villabona L, Nordfors C, Nasman A, Ramqvist T, Vlastos A, Masucci G, Dalianis T (2014) HLA-A*02 in relation to outcome in human papillomavirus positive tonsillar and base of tongue cancer. Anticancer Res 34:2369–2375
    • (2014) Anticancer Res , vol.34 , pp. 2369-2375
    • Tertipis, N.1    Villabona, L.2    Nordfors, C.3    Nasman, A.4    Ramqvist, T.5    Vlastos, A.6    Masucci, G.7    Dalianis, T.8
  • 48
    • 84904800824 scopus 로고    scopus 로고
    • Castration-resistant prostate cancer: latest evidence and therapeutic implications
    • PID: 25057303
    • Suzman DL, Antonarakis ES (2014) Castration-resistant prostate cancer: latest evidence and therapeutic implications. Ther Adv Med Oncol 6:167–179. doi:10.1177/1758834014529176
    • (2014) Ther Adv Med Oncol , vol.6 , pp. 167-179
    • Suzman, D.L.1    Antonarakis, E.S.2
  • 49
    • 0034554863 scopus 로고    scopus 로고
    • Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells
    • COI: 1:CAS:528:DC%2BD3cXptVSiurc%3D, PID: 11099318
    • Small EJ, Fratesi P, Reese DM, Strang G, Laus R, Peshwa MV, Valone FH (2000) Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells. J Clin Oncol 18:3894–3903
    • (2000) J Clin Oncol , vol.18 , pp. 3894-3903
    • Small, E.J.1    Fratesi, P.2    Reese, D.M.3    Strang, G.4    Laus, R.5    Peshwa, M.V.6    Valone, F.H.7
  • 50
    • 84912142800 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors in the treatment of prostate cancer: taking the next step in clinical development
    • COI: 1:CAS:528:DC%2BC2cXhvF2ltbjF, PID: 25345821
    • Ojemuyiwa MA, Madan RA, Dahut WL (2014) Tyrosine kinase inhibitors in the treatment of prostate cancer: taking the next step in clinical development. Expert Opin Emerg Drugs 19:459–470. doi:10.1517/14728214.2014.969239
    • (2014) Expert Opin Emerg Drugs , vol.19 , pp. 459-470
    • Ojemuyiwa, M.A.1    Madan, R.A.2    Dahut, W.L.3


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