Effect of dietary omega-3 polyunsaturated fatty acids on experimental periodontitis in the mouse

Journal of Periodontal Research

Volumn 44, Issue 2, 2009, Pages 211-216

  Bendyk, A ^a   Marino, V ^a   Zilm, P S ^a   Howe, P ^b   Bartold, P M ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

Author keywords

Docosahexaenoic acid; Experimental periodontitis; Omega 3 polyunsaturated fatty acids; Periodontal disease

Indexed keywords

EID: 84950170713     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2008.01108.x     Document Type: Article

References (28)

1. Van Dyke TE, Serhan CN. Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases. J Dent Res 2003 82 : 82 90.
2. Offenbacher S. Periodontal diseases: pathogenesis. Ann Periodontol 1996 1 : 821 878.
3. Salvi GE, Williams RC, Offenbacher S. Nonsteroidal anti-inflammatory drugs as adjuncts in the management of periodontal diseases and peri-implantitis. Curr Opin Periodontol 1997 4 : 51 58.
4. Calder PC. Polyunsaturated fatty acids and inflammation. Prostaglandins Leukot Essent Fatty Acids 2006 75 : 197 202.
5. Serhan CN. Novel chemical mediators in the resolution of inflammation: resolvins and protectins. Anesthesiol Clin 2006 24 : 341 364.
6. Heasman PA, Seymour RA, Kelly PJ. The effect of systemically-administered flurbiprofen as an adjunct to toothbrushing on the resolution of experimental gingivitis. J Clin Periodontol 1994 21 : 166 170.
7. Williams RC, Jeffcoat MK, Howell TH et al. Ibuprofen: an inhibitor of alveolar bone resorption in beagles. J Periodontal Res 1988 23 : 225 229.
8. Green GA. Understanding NSAIDs: from aspirin to COX-2. Clin Cornerstone 2001 3 : 50 60.
9. Moore RA, Derry S, Phillips CJ, McQuay HJ. Nonsteroidal anti-inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice. BMC Musculoskelet Disord 2006 7 : 79 91.
10. Alam SQ, Bergens B, Alam B. Arachidonic acid, PGE2 and Leukotriene C4 levels in gingiva and submandibular salivary glands of rats fed diets containing n3 fatty acids. Lipids 1991 26 : 895 900.
11. Vardar S, Buduneli E, Turkoglu O et al. Therapeutic versus prophylactic plus therapeutic administration of omega-3 fatty acid on edotoxin induced periodontitis in rats. J Periodontol 2004 75 : 1640 1646.
12. Vardar S, Budunei E, Baylas H, Burdeli AH, Budubeli N, Atilla G. Individual and combined effects of selective cyclo-oxygenase-2 inhibitor and omega-3 fatty acid on endotoxin induced periodontitis in rats. J Periodontol 2005 76 : 99 106.
13. Offenbacher S, Odle BM, Green MD. Inhibition of human periodontal PGE2 synthesis with selected agents. Agents Actions 1990 29 : 232 238.
14. Hasturk H, Kantarci A, Ohira T et al. RvE1 protects from local inflammation and osteoclast-mediated bone destruction in periodontitis. FASEB J 2006 20 : 401 403.
15. Vardar-Sengul S, Buduneli N, Buduneli E et al. Dietary supplementation of omega-3 fatty acid and circulating levels of interleukin-1beta, osteocalcin, and C-reactive protein in rats. J Periodontol 2006 77 : 814 820.
16. Kesavalu L, Vasudevan B, Raghu B et al. Omega-3 fatty acid effect on alveolar bone loss in rats. J Dent Res 2006 85 : 648 652.
17. Baker PJ, Dixon M, Roopenian DC. Genetic control of susceptibility to Porphyromonas gingivalis-induced alveolar bone loss in mice. Infect Immun 2000 68 : 5864 5868.
18. Alayan J, Ivanovski S, Gemmell E, Ford P, Hamlet S, Farah CS. Deficiency of iNOS contributes to Porphyromonas gingivalis-induced tissue damage. Oral Microbiol Immunol 2006 21 : 360 365.
19. Li C, Amar S. Morphometric, histomorphometric, and microcomputed tomographic analysis of periodontal inflammatory lesions in a murine model. J Periodontol 2007 78 : 1120 1128.
20. Kesavalu L, Sathishkumar S, Bakthavatchalu V et al. Rat model of polymicrobial infection, immunity, and alveolar bone resorption in periodontal disease. Infect Immun 2007 75 : 1704 1712.
21. Chiu WC, Hou YC, Yeh CL, Hu YM, Yeh SL. Effect of dietary fish oil supplementation on cellular adhesion molecule expression and tissue myeloperoxidase activity in diabetic mice with sepsis. Br J Nutr 2007 97 : 685 691.
22. Petursdottir DH, Hardardottir I. Dietary fish oil increases the number of splenic macrophages secreting TNF-alpha and IL-10 but decreases the secretion of these cytokines by splenic T cells from mice. J Nutr 2007 137 : 665 670.
23. Roman AS, Schreher J, Mackenzie AP, Nathanielsz PW. Omega-3 fatty acids and decidual cell prostaglandin production in response to the inflammatory cytokine IL-1beta. Am J Obstet Gynecol 2006 195 : 1693 1699.
24. Hong S, Gronert K, Devchand PR, Moussignac RL, Serhan CN. Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation. J Biol Chem 2003 278 : 14677 14687.
25. Marcheselli VL, Hong S, Lukiw WJ et al. Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression. J Biol Chem 2003 278 : 43807 43817.
26. Schwab JM, Serhan CN. Lipoxins and new lipid mediators in the resolution of inflammation. Curr Opin Pharmacol 2006 6 : 414 420.
27. Serhan CN, Gotlinger K, Hong S et al. Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes. J Immunol 2006 176 : 1848 1859.
28. Duffield JS, Hong S, Vaidya VS et al. Resolvin D series and protectin D1 mitigate acute kidney injury. J Immunol 2006 177 : 5902 5911.