메뉴 건너뛰기




Volumn 37, Issue 6, 2016, Pages 7507-7514

Programmed death 1 expression in the peritumoral microenvironment is associated with a poorer prognosis in classical Hodgkin lymphoma

Author keywords

Hodgkin s lymphoma; PD 1; PD L1; PD L2; Prognosis

Indexed keywords

BLEOMYCIN; DACARBAZINE; DOXORUBICIN; PROGRAMMED DEATH 1 RECEPTOR; VINBLASTINE; ANTINEOPLASTIC AGENT; CD274 PROTEIN, HUMAN; PDCD1 PROTEIN, HUMAN; PDCD1LG2 PROTEIN, HUMAN; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; TUMOR MARKER;

EID: 84949988925     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-4622-5     Document Type: Article
Times cited : (40)

References (39)
  • 1
    • 0028889323 scopus 로고
    • Fixed versus response-adapted MOPP/ABVD chemotherapy in Hodgkin’s disease. A prospective randomized trial
    • COI: 1:STN:280:DyaK287pt1ajtQ%3D%3D
    • Bjorkholm M, Axdorph U, Grimfors G, Merk K, Johansson B, Landgren O, et al. Fixed versus response-adapted MOPP/ABVD chemotherapy in Hodgkin’s disease. A prospective randomized trial. Annals Oncol. 1995;6:895–9.
    • (1995) Annals Oncol , vol.6 , pp. 895-899
    • Bjorkholm, M.1    Axdorph, U.2    Grimfors, G.3    Merk, K.4    Johansson, B.5    Landgren, O.6
  • 2
    • 68049131240 scopus 로고    scopus 로고
    • Salvage therapy for Hodgkin’s lymphoma
    • PID: 19390313
    • Quddus F, Armitage JO. Salvage therapy for Hodgkin’s lymphoma. Cancer J. 2009;15:161–3.
    • (2009) Cancer J , vol.15 , pp. 161-163
    • Quddus, F.1    Armitage, J.O.2
  • 3
    • 0032548107 scopus 로고    scopus 로고
    • A prognostic score for advanced Hodgkin’s disease. International prognostic factors project on advanced Hodgkin’s disease
    • COI: 1:STN:280:DyaK1M%2FisFenuw%3D%3D, PID: 9819449
    • Hasenclever D, Diehl V. A prognostic score for advanced Hodgkin’s disease. International prognostic factors project on advanced Hodgkin’s disease. N Engl J Med. 1998;339:1506–14.
    • (1998) N Engl J Med , vol.339 , pp. 1506-1514
    • Hasenclever, D.1    Diehl, V.2
  • 4
    • 0034596948 scopus 로고    scopus 로고
    • Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
    • COI: 1:CAS:528:DC%2BD3cXntFSlt7o%3D, PID: 11015443
    • Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, Nishimura H, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med. 2000;192:1027–34.
    • (2000) J Exp Med , vol.192 , pp. 1027-1034
    • Freeman, G.J.1    Long, A.J.2    Iwai, Y.3    Bourque, K.4    Chernova, T.5    Nishimura, H.6
  • 5
    • 34547794178 scopus 로고    scopus 로고
    • PD-1 and PD-1 ligands: from discovery to clinical application
    • COI: 1:CAS:528:DC%2BD2sXhtValtbbO, PID: 17606980
    • Okazaki T, Honjo T. PD-1 and PD-1 ligands: from discovery to clinical application. Int Immunol. 2007;19:813–24.
    • (2007) Int Immunol , vol.19 , pp. 813-824
    • Okazaki, T.1    Honjo, T.2
  • 6
    • 42649125225 scopus 로고    scopus 로고
    • PD-1 and its ligands in tolerance and immunity
    • COI: 1:CAS:528:DC%2BD1cXltlWktrY%3D, PID: 18173375
    • Keir ME, Butte MJ, Freeman GJ, Sharpe AH. PD-1 and its ligands in tolerance and immunity. Annu Rev Immunol. 2008;26:677–704.
    • (2008) Annu Rev Immunol , vol.26 , pp. 677-704
    • Keir, M.E.1    Butte, M.J.2    Freeman, G.J.3    Sharpe, A.H.4
  • 7
    • 78449243489 scopus 로고    scopus 로고
    • Immune checkpoint proteins: a new therapeutic paradigm for cancer--preclinical background: CTLA-4 and PD-1 blockade
    • COI: 1:CAS:528:DC%2BC3cXhsVWrtbfI, PID: 21074057
    • Weber J. Immune checkpoint proteins: a new therapeutic paradigm for cancer--preclinical background: CTLA-4 and PD-1 blockade. Semin Oncol. 2010;37:430–9.
    • (2010) Semin Oncol , vol.37 , pp. 430-439
    • Weber, J.1
  • 9
    • 84923294851 scopus 로고    scopus 로고
    • Co-expression of PD-1 and PD-L1 predicts poor outcome in nasopharyngeal carcinoma
    • PID: 25702326
    • Zhang J, Fang W, Qin T, Yang Y, Hong S, Liang W, et al. Co-expression of PD-1 and PD-L1 predicts poor outcome in nasopharyngeal carcinoma. Med Oncol. 2015;32:86.
    • (2015) Med Oncol , vol.32 , pp. 86
    • Zhang, J.1    Fang, W.2    Qin, T.3    Yang, Y.4    Hong, S.5    Liang, W.6
  • 10
    • 84925969186 scopus 로고    scopus 로고
    • Association of PD-L1 expression on tumor-infiltrating mononuclear cells and overall survival in patients with urothelial carcinoma
    • COI: 1:STN:280:DC%2BC2MvnsFOjug%3D%3D, PID: 25600565
    • Bellmunt J, Mullane SA, Werner L, Fay AP, Callea M, Leow JJ, et al. Association of PD-L1 expression on tumor-infiltrating mononuclear cells and overall survival in patients with urothelial carcinoma. Ann Oncol. 2015;26:812–7.
    • (2015) Ann Oncol , vol.26 , pp. 812-817
    • Bellmunt, J.1    Mullane, S.A.2    Werner, L.3    Fay, A.P.4    Callea, M.5    Leow, J.J.6
  • 11
    • 84903730485 scopus 로고    scopus 로고
    • Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer
    • COI: 1:CAS:528:DC%2BC2cXosFansb4%3D, PID: 24842267
    • Muenst S, Schaerli AR, Gao F, Daster S, Trella E, Droeser RA, et al. Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer. Breast Cancer Res Treat. 2014;146:15–24.
    • (2014) Breast Cancer Res Treat , vol.146 , pp. 15-24
    • Muenst, S.1    Schaerli, A.R.2    Gao, F.3    Daster, S.4    Trella, E.5    Droeser, R.A.6
  • 12
    • 84898843963 scopus 로고    scopus 로고
    • Protein expression of programmed death 1 ligand 1 and ligand 2 independently predict poor prognosis in surgically resected lung adenocarcinoma
    • Zhang Y, Wang L, Li Y, Pan Y, Wang R, Hu H, et al. Protein expression of programmed death 1 ligand 1 and ligand 2 independently predict poor prognosis in surgically resected lung adenocarcinoma. OncoTargets Ther. 2014;7:567–73.
    • (2014) OncoTargets Ther , vol.7 , pp. 567-573
    • Zhang, Y.1    Wang, L.2    Li, Y.3    Pan, Y.4    Wang, R.5    Hu, H.6
  • 13
    • 84877704099 scopus 로고    scopus 로고
    • Clinical impact of programmed cell death ligand 1 expression in colorectal cancer
    • COI: 1:CAS:528:DC%2BC3sXktlCgtLs%3D, PID: 23478000
    • Droeser RA, Hirt C, Viehl CT, Frey DM, Nebiker C, Huber X, et al. Clinical impact of programmed cell death ligand 1 expression in colorectal cancer. Eur J Cancer. 2013;49:2233–42.
    • (2013) Eur J Cancer , vol.49 , pp. 2233-2242
    • Droeser, R.A.1    Hirt, C.2    Viehl, C.T.3    Frey, D.M.4    Nebiker, C.5    Huber, X.6
  • 15
    • 84938740731 scopus 로고    scopus 로고
    • Programmed death-1 (PD-1), programmed death-ligand 1 (PD-L1)
    • EBER) expression in Hodgkin lymphoma, Ann Hematol
    • Paydas S, Bagir E, Seydaoglu G, Ercolak V, Ergin M (2015) Programmed death-1 (PD-1), programmed death-ligand 1 (PD-L1), and EBV-encoded RNA (EBER) expression in Hodgkin lymphoma. Ann Hematol
    • (2015) and EBV-encoded RNA
    • Paydas, S.1    Bagir, E.2    Seydaoglu, G.3    Ercolak, V.4    Ergin, M.5
  • 17
    • 0032978711 scopus 로고    scopus 로고
    • Detection of Epstein-Barr virus in Korean peripheral T-cell lymphoma
    • COI: 1:STN:280:DyaK1M7ntVehug%3D%3D, PID: 10072112
    • Huh J, Cho K, Heo DS, Kim JE, Kim CW. Detection of Epstein-Barr virus in Korean peripheral T-cell lymphoma. Am J Hematol. 1999;60:205–14.
    • (1999) Am J Hematol , vol.60 , pp. 205-214
    • Huh, J.1    Cho, K.2    Heo, D.S.3    Kim, J.E.4    Kim, C.W.5
  • 18
    • 70349408300 scopus 로고    scopus 로고
    • Increased programmed death-1+ tumor-infiltrating lymphocytes in classical Hodgkin lymphoma substantiate reduced overall survival
    • COI: 1:CAS:528:DC%2BD1MXhsVensrfJ, PID: 19695683
    • Muenst S, Hoeller S, Dirnhofer S, Tzankov A. Increased programmed death-1+ tumor-infiltrating lymphocytes in classical Hodgkin lymphoma substantiate reduced overall survival. Hum Pathol. 2009;40:1715–22.
    • (2009) Hum Pathol , vol.40 , pp. 1715-1722
    • Muenst, S.1    Hoeller, S.2    Dirnhofer, S.3    Tzankov, A.4
  • 20
    • 34447646310 scopus 로고    scopus 로고
    • Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses
    • COI: 1:CAS:528:DC%2BD2sXosFeqtrk%3D, PID: 17629517
    • Butte MJ, Keir ME, Phamduy TB, Sharpe AH, Freeman GJ. Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity. 2007;27:111–22.
    • (2007) Immunity , vol.27 , pp. 111-122
    • Butte, M.J.1    Keir, M.E.2    Phamduy, T.B.3    Sharpe, A.H.4    Freeman, G.J.5
  • 21
    • 77956496386 scopus 로고    scopus 로고
    • B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance
    • COI: 1:CAS:528:DC%2BC3cXhtFersbbP, PID: 20472828
    • Park JJ, Omiya R, Matsumura Y, Sakoda Y, Kuramasu A, Augustine MM, et al. B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance. Blood. 2010;116:1291–8.
    • (2010) Blood , vol.116 , pp. 1291-1298
    • Park, J.J.1    Omiya, R.2    Matsumura, Y.3    Sakoda, Y.4    Kuramasu, A.5    Augustine, M.M.6
  • 22
    • 84864324543 scopus 로고    scopus 로고
    • Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2
    • COI: 1:CAS:528:DC%2BC38XoslShsr4%3D, PID: 22641383
    • Yokosuka T, Takamatsu M, Kobayashi-Imanishi W, Hashimoto-Tane A, Azuma M, Saito T. Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2. J Exp Med. 2012;209:1201–17.
    • (2012) J Exp Med , vol.209 , pp. 1201-1217
    • Yokosuka, T.1    Takamatsu, M.2    Kobayashi-Imanishi, W.3    Hashimoto-Tane, A.4    Azuma, M.5    Saito, T.6
  • 23
    • 4444317516 scopus 로고    scopus 로고
    • Pd-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3zeta signalosome and downstream signaling to PKCtheta
    • COI: 1:CAS:528:DC%2BD2cXnsFGmu7Y%3D, PID: 15358536
    • Sheppard KA, Fitz LJ, Lee JM, Benander C, George JA, Wooters J, et al. Pd-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3zeta signalosome and downstream signaling to PKCtheta. FEBS Lett. 2004;574:37–41.
    • (2004) FEBS Lett , vol.574 , pp. 37-41
    • Sheppard, K.A.1    Fitz, L.J.2    Lee, J.M.3    Benander, C.4    George, J.A.5    Wooters, J.6
  • 24
    • 77957781776 scopus 로고    scopus 로고
    • Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
    • COI: 1:CAS:528:DC%2BC3cXht1elu73K, PID: 20890291
    • Quigley M, Pereyra F, Nilsson B, Porichis F, Fonseca C, Eichbaum Q, et al. Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF. Nat Med. 2010;16:1147–51.
    • (2010) Nat Med , vol.16 , pp. 1147-1151
    • Quigley, M.1    Pereyra, F.2    Nilsson, B.3    Porichis, F.4    Fonseca, C.5    Eichbaum, Q.6
  • 25
    • 77950525439 scopus 로고    scopus 로고
    • Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection
    • COI: 1:CAS:528:DC%2BC3cXivVKjsr8%3D, PID: 20208540
    • Said EA, Dupuy FP, Trautmann L, Zhang Y, Shi Y, El-Far M, et al. Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection. Nat Med. 2010;16:452–9.
    • (2010) Nat Med , vol.16 , pp. 452-459
    • Said, E.A.1    Dupuy, F.P.2    Trautmann, L.3    Zhang, Y.4    Shi, Y.5    El-Far, M.6
  • 26
    • 73949088551 scopus 로고    scopus 로고
    • PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
    • COI: 1:CAS:528:DC%2BD1MXhs1WlsbrP, PID: 20008522
    • Francisco LM, Salinas VH, Brown KE, Vanguri VK, Freeman GJ, Kuchroo VK, et al. PD-L1 regulates the development, maintenance, and function of induced regulatory T cells. J Exp Med. 2009;206:3015–29.
    • (2009) J Exp Med , vol.206 , pp. 3015-3029
    • Francisco, L.M.1    Salinas, V.H.2    Brown, K.E.3    Vanguri, V.K.4    Freeman, G.J.5    Kuchroo, V.K.6
  • 27
    • 84925688346 scopus 로고    scopus 로고
    • PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation
    • COI: 1:CAS:528:DC%2BC2MXhtF2itLrP, PID: 25809635
    • Patsoukis N, Bardhan K, Chatterjee P, Sari D, Liu B, Bell LN, et al. PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation. Nat Commun. 2015;6:6692.
    • (2015) Nat Commun , vol.6 , pp. 6692
    • Patsoukis, N.1    Bardhan, K.2    Chatterjee, P.3    Sari, D.4    Liu, B.5    Bell, L.N.6
  • 28
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • COI: 1:CAS:528:DC%2BC38XhtV2rsbnJ, PID: 22658128
    • Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012;366:2455–65.
    • (2012) N Engl J Med , vol.366 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3    Hwu, W.J.4    Topalian, S.L.5    Hwu, P.6
  • 29
    • 84907651084 scopus 로고    scopus 로고
    • Clinical activity and biomarkers of MEDI4736, an anti-PD-L1 antibody, in patients with NSCLC
    • Brahmer JR, Rizvi NA, Lutzky J (2014b) Clinical activity and biomarkers of MEDI4736, an anti-PD-L1 antibody, in patients with NSCLC. ASCO Meet Abstr 32:8021
    • (2014) ASCO Meet Abstr , vol.32 , pp. 8021
    • Brahmer, J.R.1    Rizvi, N.A.2    Lutzky, J.3
  • 30
    • 84923078390 scopus 로고    scopus 로고
    • MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
    • COI: 1:CAS:528:DC%2BC2cXitFamsrjE, PID: 25428503
    • Powles T, Eder JP, Fine GD, Braiteh FS, Loriot Y, Cruz C, et al. MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer. Nature. 2014;515:558–62.
    • (2014) Nature , vol.515 , pp. 558-562
    • Powles, T.1    Eder, J.P.2    Fine, G.D.3    Braiteh, F.S.4    Loriot, Y.5    Cruz, C.6
  • 31
    • 84898973055 scopus 로고    scopus 로고
    • Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
    • COI: 1:CAS:528:DC%2BC2cXpsVSku74%3D, PID: 24590637
    • Topalian SL, Sznol M, McDermott DF, Kluger HM, Carvajal RD, Sharfman WH, et al. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol. 2014;32:1020–30.
    • (2014) J Clin Oncol , vol.32 , pp. 1020-1030
    • Topalian, S.L.1    Sznol, M.2    McDermott, D.F.3    Kluger, H.M.4    Carvajal, R.D.5    Sharfman, W.H.6
  • 32
    • 84925222119 scopus 로고    scopus 로고
    • Nivolumab in previously untreated melanoma without BRAF mutation
    • COI: 1:CAS:528:DC%2BC2MXisFGqsLg%3D, PID: 25399552
    • Robert C, Long GV, Brady B, Dutriaux C, Maio M, Mortier L, et al. Nivolumab in previously untreated melanoma without BRAF mutation. N Engl J Med. 2015;372:320–30.
    • (2015) N Engl J Med , vol.372 , pp. 320-330
    • Robert, C.1    Long, G.V.2    Brady, B.3    Dutriaux, C.4    Maio, M.5    Mortier, L.6
  • 33
    • 84908354848 scopus 로고    scopus 로고
    • Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
    • COI: 1:CAS:528:DC%2BC2cXhtFGlsb%2FN, PID: 25034862
    • Robert C, Ribas A, Wolchok JD, Hodi FS, Hamid O, Kefford R, et al. Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet. 2014;384:1109–17.
    • (2014) Lancet , vol.384 , pp. 1109-1117
    • Robert, C.1    Ribas, A.2    Wolchok, J.D.3    Hodi, F.S.4    Hamid, O.5    Kefford, R.6
  • 34
    • 84936791837 scopus 로고    scopus 로고
    • Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
    • COI: 1:CAS:528:DC%2BC2MXht12qu7%2FJ, PID: 26028407
    • Brahmer J, Reckamp KL, Baas P, Crino L, Eberhardt WE, Poddubskaya E, et al. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Med. 2015;373:123–35.
    • (2015) N Engl J Med , vol.373 , pp. 123-135
    • Brahmer, J.1    Reckamp, K.L.2    Baas, P.3    Crino, L.4    Eberhardt, W.E.5    Poddubskaya, E.6
  • 36
  • 37
    • 84907651086 scopus 로고    scopus 로고
    • First-line nivolumab (anti-PD-1; BMS-936558, ONO-4538) monotherapy in advanced NSCLC: safety, efficacy, and correlation of outcomes with PD-L1 status
    • Gettinger SN, Shepherd FA, Antonia SJ. First-line nivolumab (anti-PD-1; BMS-936558, ONO-4538) monotherapy in advanced NSCLC: safety, efficacy, and correlation of outcomes with PD-L1 status. ASCO Meet Abstr. 2014;32:8024.
    • (2014) ASCO Meet Abstr , vol.32 , pp. 8024
    • Gettinger, S.N.1    Shepherd, F.A.2    Antonia, S.J.3
  • 38
    • 84971325923 scopus 로고    scopus 로고
    • MK-3475 (anti-PD-1 monoclonal antibody) for non-small cell lung cancer (NSCLC): antitumor activity and association with tumor PD-L1 expression [abstract]
    • Gandhi L (2014) MK-3475 (anti-PD-1 monoclonal antibody) for non-small cell lung cancer (NSCLC): antitumor activity and association with tumor PD-L1 expression [abstract]. Proc Ann Meet AACR CT105
    • (2014) Proc Ann Meet AACR CT105
    • Gandhi, L.1
  • 39
    • 84930630766 scopus 로고    scopus 로고
    • PD-1/PD-L1 inhibitors
    • COI: 1:CAS:528:DC%2BC2MXptFShu7k%3D, PID: 26047524
    • Sunshine J, Taube JM. PD-1/PD-L1 inhibitors. Curr Opin Pharmacol. 2015;23:32.
    • (2015) Curr Opin Pharmacol , vol.23 , pp. 32
    • Sunshine, J.1    Taube, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.