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Volumn 11, Issue 3, 2016, Pages 277-292

Systematic Review of the Side Effects Associated With Anti-HER2-Targeted Therapies Used in the Treatment of Breast Cancer, on Behalf of the EORTC Quality of Life Group

Author keywords

[No Author keywords available]

Indexed keywords

AFATINIB; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; LAPATINIB; NERATINIB; PERTUZUMAB; TRASTUZUMAB; EPIDERMAL GROWTH FACTOR RECEPTOR 2;

EID: 84949945164     PISSN: 17762596     EISSN: 1776260X     Source Type: Journal    
DOI: 10.1007/s11523-015-0409-2     Document Type: Review
Times cited : (32)

References (48)
  • 1
    • 38049025794 scopus 로고    scopus 로고
    • Review: side effects of approved molecular targeted therapies in solid cancers
    • COI: 1:CAS:528:DC%2BD1cXhslSntb8%3D, PID: 18165622
    • Widakowich CCGJ, de Azambuja E, Dinh P, Awada A (2007) Review: side effects of approved molecular targeted therapies in solid cancers. Oncologist 12(12):1443–1455
    • (2007) Oncologist , vol.12 , Issue.12 , pp. 1443-1455
    • Widakowich, C.C.G.J.1    de Azambuja, E.2    Dinh, P.3    Awada, A.4
  • 2
    • 0024337144 scopus 로고
    • Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
    • COI: 1:STN:280:DyaL1M3kt1Wntg%3D%3D, PID: 2470152
    • Slamon D, Godolphin W, Jones LA, Holt JA et al (1989) Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244(4905):707–712
    • (1989) Science , vol.244 , Issue.4905 , pp. 707-712
    • Slamon, D.1    Godolphin, W.2    Jones, L.A.3    Holt, J.A.4
  • 3
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HERs monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • COI: 1:CAS:528:DyaK1MXmtlWrurk%3D, PID: 10561337
    • Cobleigh M, Vogel C, Tripathy D, Robert N, Scholl S, Fehrenbacher L, Wolter J, Paton V, Shak S, Lieberman G, Slamon D (1999) Multinational study of the efficacy and safety of humanized anti-HERs monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 17(9):2639–2648
    • (1999) J Clin Oncol , vol.17 , Issue.9 , pp. 2639-2648
    • Cobleigh, M.1    Vogel, C.2    Tripathy, D.3    Robert, N.4    Scholl, S.5    Fehrenbacher, L.6    Wolter, J.7    Paton, V.8    Shak, S.9    Lieberman, G.10    Slamon, D.11
  • 4
    • 33845369142 scopus 로고    scopus 로고
    • First—select the target: Better choice of adjuvant treatments for breast cancer patients
    • COI: 1:STN:280:DC%2BD28jhtlWgsg%3D%3D, PID: 17071934
    • Goldhirsch A, Coates AS, Gelber RD et al (2006) First—select the target: Better choice of adjuvant treatments for breast cancer patients. Ann Oncol 17:1772–1776
    • (2006) Ann Oncol , vol.17 , pp. 1772-1776
    • Goldhirsch, A.1    Coates, A.S.2    Gelber, R.D.3
  • 7
    • 77949903478 scopus 로고    scopus 로고
    • Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy
    • COI: 1:CAS:528:DC%2BC3cXktF2ltLg%3D, PID: 20124182
    • Baselga J, Gelmon KA, Verma S, Wardley A, Conte P, Miles D, Bianchi G, Cortes J, McNally VA, Ross GA, Fumoleau P, Gianni L (2010) Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy. J Clin Oncol 28(7):1138–1144. doi:10.1200/JCO.2009.24.2024
    • (2010) J Clin Oncol , vol.28 , Issue.7 , pp. 1138-1144
    • Baselga, J.1    Gelmon, K.A.2    Verma, S.3    Wardley, A.4    Conte, P.5    Miles, D.6    Bianchi, G.7    Cortes, J.8    McNally, V.A.9    Ross, G.A.10    Fumoleau, P.11    Gianni, L.12
  • 8
    • 52049088286 scopus 로고    scopus 로고
    • Cardiac toxicity and efficacy of trastuzumab combined with pertuzumab in patients with trastuzumab-insensitive human epidermal growth factor receptor 2-positive metastatic breast cancer
    • COI: 1:CAS:528:DC%2BD1cXlsV2qtLc%3D, PID: 18451236
    • Portera CC, Walshe JM, Rosing DR, Denduluri N, Berman AW, Vatas U, Velarde M, Chow CK, Steinberg SM, Nguyen D, Yang SX, Swain SM (2008) Cardiac toxicity and efficacy of trastuzumab combined with pertuzumab in patients with trastuzumab-insensitive human epidermal growth factor receptor 2-positive metastatic breast cancer. Clin Cancer Res 14(9):2710–2716. doi:10.1158/1078-0432.ccr-07-4636
    • (2008) Clin Cancer Res , vol.14 , Issue.9 , pp. 2710-2716
    • Portera, C.C.1    Walshe, J.M.2    Rosing, D.R.3    Denduluri, N.4    Berman, A.W.5    Vatas, U.6    Velarde, M.7    Chow, C.K.8    Steinberg, S.M.9    Nguyen, D.10    Yang, S.X.11    Swain, S.M.12
  • 11
    • 84888004978 scopus 로고    scopus 로고
    • A phase two randomised trial of neratinib monotherapy versus lapatinib plus capecitabine combination therapy in patients with HER2+ advanced breast cancer
    • Martin M, Bonneterre J, Geyer CE, Jr., Ito Y, Ro J, Lang I, Kim S-B, Germa C, Vermette J, Wang K, Wang K, Awada A (2013) A phase two randomised trial of neratinib monotherapy versus lapatinib plus capecitabine combination therapy in patients with HER2+ advanced breast cancer. Eur J Cancer 49 (18):3763–3772.
    • (2013) Eur J Cancer , vol.49 , Issue.18 , pp. 3763-3772
    • Martin, M.1    Bonneterre, J.2    Geyer, C.E.3    Ito, Y.4    Ro, J.5    Lang, I.6    Kim, S.-B.7    Germa, C.8    Vermette, J.9    Wang, K.10    Wang, K.11    Awada, A.12
  • 12
    • 26844503270 scopus 로고    scopus 로고
    • Trastuzumab after Adjuvant Chemotherapy in HER2 - Positive Breast Cancer
    • COI: 1:CAS:528:DC%2BD2MXhtFansr3L, PID: 16236737
    • Piccart-Gebhart M, Procter M, Leyland-Jones B, Goldhirsch A, Untch M, Smith I et al (2005) Trastuzumab after Adjuvant Chemotherapy in HER2 - Positive Breast Cancer. N Engl J Med 353(16):1659–1672
    • (2005) N Engl J Med , vol.353 , Issue.16 , pp. 1659-1672
    • Piccart-Gebhart, M.1    Procter, M.2    Leyland-Jones, B.3    Goldhirsch, A.4    Untch, M.5    Smith, I.6
  • 13
    • 78149399425 scopus 로고    scopus 로고
    • Cardiac toxicity of trastuzumab: experience at the Ghent Unversity Hospital, Belgium
    • COI: 1:STN:280:DC%2BC3M%2FhvVehtg%3D%3D, PID: 21128555
    • Lamot C, Rottey S, De Backer T, Van Bortel L, Robays H, Van Belle S, Denys H, Cocquyt V (2010) Cardiac toxicity of trastuzumab: experience at the Ghent Unversity Hospital, Belgium. Acta Clin Belg 65(5):300–304
    • (2010) Acta Clin Belg , vol.65 , Issue.5 , pp. 300-304
    • Lamot, C.1    Rottey, S.2    De Backer, T.3    Van Bortel, L.4    Robays, H.5    Van Belle, S.6    Denys, H.7    Cocquyt, V.8
  • 14
    • 66949117122 scopus 로고    scopus 로고
    • Trastuzumab induces gastrointestinal side effects in HER2-overexpressing breast cancer patients
    • COI: 1:CAS:528:DC%2BD1MXitVOmtbk%3D
    • Al-Dasooqi N, Bowen JM, Gibson RJ, Sullivan T, Lees J, Keefe DM (2009) Trastuzumab induces gastrointestinal side effects in HER2-overexpressing breast cancer patients. Investig New Drugs 27(2):173–178
    • (2009) Investig New Drugs , vol.27 , Issue.2 , pp. 173-178
    • Al-Dasooqi, N.1    Bowen, J.M.2    Gibson, R.J.3    Sullivan, T.4    Lees, J.5    Keefe, D.M.6
  • 16
    • 68049122102 scopus 로고    scopus 로고
    • The PG (2009) Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
    • PID: 19621072
    • Moher D, Liberati A, Tetzlaff J, Altman D (2009) The PG (2009) Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. PLoS Med 6(7):e1000097. doi:10.1371/journalpmed1000097
    • (2009) PLoS Med , vol.6 , Issue.7 , pp. e1000097
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.4
  • 17
    • 84901609051 scopus 로고    scopus 로고
    • Systematic review of the side effects associated with tyrosine kinase inhibitors used in the treatment of gastrointestinal stromal tumours on behalf of the EORTC Quality of Life Group
    • Sodergren SC WA, Efficace F, Sprangers M, Fitzsimmons D, Bottomley A, Johnson CD. (2014) Systematic review of the side effects associated with tyrosine kinase inhibitors used in the treatment of gastrointestinal stromal tumours on behalf of the EORTC Quality of Life Group. Crit Rev Oncol Hematol 91(1):35–46
    • (2014) Crit Rev Oncol Hematol , vol.91 , Issue.1 , pp. 35-46
    • Sodergren, S.C.W.A.1    Efficace, F.2    Sprangers, M.3    Fitzsimmons, D.4    Bottomley, A.5    Johnson, C.D.6
  • 24
    • 72449139053 scopus 로고    scopus 로고
    • Randomized phase III trial of trastuzumab monotherapy followed by trastuzumab plus docetaxel versus trastuzumab plus docetaxel as first-line therapy in patients with HER2-positive metastatic breast cancer: The JO17360 Trial Group
    • COI: 1:CAS:528:DC%2BD1MXhsFaqtr3N, PID: 19690954
    • Inoue K, Nakagami K, Mizutani M, Hozumi Y, Fujiwara Y, Tsukamoto F, Saito M, Miura S, Eguchi K, Shinkai T, Ando M, Watanabe T, Masuda N, Ohashi Y, Sano M, Noguchi S (2010) Randomized phase III trial of trastuzumab monotherapy followed by trastuzumab plus docetaxel versus trastuzumab plus docetaxel as first-line therapy in patients with HER2-positive metastatic breast cancer: The JO17360 Trial Group. Breast Cancer Res Treat 119(1):127–136. doi:10.1007/s10549-009-0498-7
    • (2010) Breast Cancer Res Treat , vol.119 , Issue.1 , pp. 127-136
    • Inoue, K.1    Nakagami, K.2    Mizutani, M.3    Hozumi, Y.4    Fujiwara, Y.5    Tsukamoto, F.6    Saito, M.7    Miura, S.8    Eguchi, K.9    Shinkai, T.10    Ando, M.11    Watanabe, T.12    Masuda, N.13    Ohashi, Y.14    Sano, M.15    Noguchi, S.16
  • 27
    • 84928200454 scopus 로고    scopus 로고
    • Patients' preferences for subcutaneous trastuzumab versus conventional intravenous infusion for the adjuvant treatment of HER2-positive early breast cancer: final analysis of 488 patients in the international, randomized, two-cohort PrefHer study
    • PID: 25070545
    • Pivot X, Gligorov J, Mueller V, Curigliano G, Knoop A, Verma S, Jenkins V, Scotto N, Osborne S, Fallowfield L, PrefHer Study G (2014) Patients' preferences for subcutaneous trastuzumab versus conventional intravenous infusion for the adjuvant treatment of HER2-positive early breast cancer: final analysis of 488 patients in the international, randomized, two-cohort PrefHer study. Ann Oncol 25(10):1979–1987. doi:10.1093/annonc/mdu364
    • (2014) Ann Oncol , vol.25 , Issue.10 , pp. 1979-1987
    • Pivot, X.1    Gligorov, J.2    Mueller, V.3    Curigliano, G.4    Knoop, A.5    Verma, S.6    Jenkins, V.7    Scotto, N.8    Osborne, S.9    Fallowfield, L.10    PrefHer Study, G.11
  • 30
    • 61649118623 scopus 로고    scopus 로고
    • Single-agent lapatinib for HER2-overexpressing advanced or metastatic breast cancer that progressed on first- or second-line trastuzumab-containing regimens
    • COI: 1:STN:280:DC%2BD1MzmtlGltQ%3D%3D, PID: 19179558
    • Blackwell KL, Pegram MD, Tan-Chiu E, Schwartzberg LS, Arbushites MC, Maltzman JD, Forster JK, Rubin SD, Stein SH, Burstein HJ (2009) Single-agent lapatinib for HER2-overexpressing advanced or metastatic breast cancer that progressed on first- or second-line trastuzumab-containing regimens. Ann Oncol 20(6):1026–1031. doi:10.1093/annonc/mdn759
    • (2009) Ann Oncol , vol.20 , Issue.6 , pp. 1026-1031
    • Blackwell, K.L.1    Pegram, M.D.2    Tan-Chiu, E.3    Schwartzberg, L.S.4    Arbushites, M.C.5    Maltzman, J.D.6    Forster, J.K.7    Rubin, S.D.8    Stein, S.H.9    Burstein, H.J.10
  • 31
    • 44849108294 scopus 로고    scopus 로고
    • A phase II study of lapatinib monotherapy in chemotherapy-refractory HER2-positive and HER2-negative advanced or metastatic breast cancer
    • COI: 1:STN:280:DC%2BD1czktlSgsA%3D%3D, PID: 18283035
    • Burstein HJ, Storniolo AM, Franco S, Forster J, Stein S, Rubin S, Salazar VM, Blackwell KL (2008) A phase II study of lapatinib monotherapy in chemotherapy-refractory HER2-positive and HER2-negative advanced or metastatic breast cancer. Ann Oncol 19(6):1068–1074. doi:10.1093/annonc/mdm601
    • (2008) Ann Oncol , vol.19 , Issue.6 , pp. 1068-1074
    • Burstein, H.J.1    Storniolo, A.M.2    Franco, S.3    Forster, J.4    Stein, S.5    Rubin, S.6    Salazar, V.M.7    Blackwell, K.L.8
  • 34
    • 66149093901 scopus 로고    scopus 로고
    • Lapatinib monotherapy in patients with HER2-overexpressing relapsed or refractory inflammatory breast cancer: final results and survival of the expanded HER2+ cohort in EGF103009, a phase II study
    • COI: 1:CAS:528:DC%2BD1MXms12jtbY%3D, PID: 19394894
    • Kaufman B, Trudeau M, Awada A, Blackwell K, Bachelot T, Salazar V, DeSilvio M, Westlund R, Zaks T, Spector N, Johnston S (2009) Lapatinib monotherapy in patients with HER2-overexpressing relapsed or refractory inflammatory breast cancer: final results and survival of the expanded HER2+ cohort in EGF103009, a phase II study. Lancet Oncol 10(6):581–588. doi:10.1016/S1470-2045%2809%2970087-7
    • (2009) Lancet Oncol , vol.10 , Issue.6 , pp. 581-588
    • Kaufman, B.1    Trudeau, M.2    Awada, A.3    Blackwell, K.4    Bachelot, T.5    Salazar, V.6    DeSilvio, M.7    Westlund, R.8    Zaks, T.9    Spector, N.10    Johnston, S.11
  • 37
    • 73349085919 scopus 로고    scopus 로고
    • Understanding the mechanisms behind trastuzumab therapy for human epidermal growth factor receptor 2-positive breast cancer
    • COI: 1:CAS:528:DC%2BC3cXhtVWitro%3D, PID: 19884552
    • Spector NLBK (2009) Understanding the mechanisms behind trastuzumab therapy for human epidermal growth factor receptor 2-positive breast cancer. J Clin Oncol 27(34):5838–5847
    • (2009) J Clin Oncol , vol.27 , Issue.34 , pp. 5838-5847
    • Spector, N.L.B.K.1
  • 39
    • 4444327078 scopus 로고    scopus 로고
    • How Accurate Is Clinician Reporting of Chemotherapy Adverse Effects? A Comparison With Patient-Reported Symptoms From the Quality-of-Life Questionnaire C30
    • PID: 15337796
    • Fromme EEK, Mori M, Hsieh Y, Beer T (2004) How Accurate Is Clinician Reporting of Chemotherapy Adverse Effects? A Comparison With Patient-Reported Symptoms From the Quality-of-Life Questionnaire C30. J Clin Oncol 22(17):3485–3490
    • (2004) J Clin Oncol , vol.22 , Issue.17 , pp. 3485-3490
    • Fromme, E.E.K.1    Mori, M.2    Hsieh, Y.3    Beer, T.4
  • 40
    • 70349337359 scopus 로고    scopus 로고
    • Trastuzumab-induced cardiomyopathy: not as benign as it looks? A retrospective study
    • COI: 1:CAS:528:DC%2BD1MXhtFyntL7L, PID: 19786253
    • Guglin M, Hartlage G, Reynolds C, Chen R, Patel V (2009) Trastuzumab-induced cardiomyopathy: not as benign as it looks? A retrospective study. J Card Fail 15(8):651–657. doi:10.1016/j.cardfail.2009.04.011
    • (2009) J Card Fail , vol.15 , Issue.8 , pp. 651-657
    • Guglin, M.1    Hartlage, G.2    Reynolds, C.3    Chen, R.4    Patel, V.5
  • 42
    • 17144371333 scopus 로고    scopus 로고
    • Phase II Study of Efficacy, Safety, and Pharmacokinetics of Trastuzumab Monotherapy Administered on a 3-Weekly Schedule
    • COI: 1:CAS:528:DC%2BD2MXjsVyiu7w%3D, PID: 15800309
    • Baselga J, Carbonell X, Castaneda-Soto N-J, Clemens M, Green M, Harvey V, Morales S, Barton C, Ghahramani P (2005) Phase II Study of Efficacy, Safety, and Pharmacokinetics of Trastuzumab Monotherapy Administered on a 3-Weekly Schedule. J Clin Oncol 23(10):2162–2171
    • (2005) J Clin Oncol , vol.23 , Issue.10 , pp. 2162-2171
    • Baselga, J.1    Carbonell, X.2    Castaneda-Soto, N.-J.3    Clemens, M.4    Green, M.5    Harvey, V.6    Morales, S.7    Barton, C.8    Ghahramani, P.9
  • 43
    • 80755133435 scopus 로고    scopus 로고
    • Incidence of Severe Adverse Events Requiring Hospital Care after Trastuzumab Infusion for Metastatic Breast Cancer: A Nationwide Survey using an Administrative Claim Database
    • COI: 1:CAS:528:DC%2BC3MXhs1emt7fF, PID: 21973020
    • Horiguchi H, Yasunaga H, Hashimoto H, Matsuda S (2011) Incidence of Severe Adverse Events Requiring Hospital Care after Trastuzumab Infusion for Metastatic Breast Cancer: A Nationwide Survey using an Administrative Claim Database. Breast J 17(6):683–685. doi:10.1111/j.1524-4741.2011.01170.x
    • (2011) Breast J , vol.17 , Issue.6 , pp. 683-685
    • Horiguchi, H.1    Yasunaga, H.2    Hashimoto, H.3    Matsuda, S.4
  • 44
    • 84856592577 scopus 로고    scopus 로고
    • Tumor control versus adverse events with targeted anticancer therapies
    • COI: 1:CAS:528:DC%2BC38XhslGmtrg%3D
    • Keefe DMK, Bateman EH (2012) Tumor control versus adverse events with targeted anticancer therapies. Nat Rev Clin Oncol 9:98–109
    • (2012) Nat Rev Clin Oncol , vol.9 , pp. 98-109
    • Keefe, D.M.K.1    Bateman, E.H.2
  • 48
    • 84864066561 scopus 로고    scopus 로고
    • Overall survival benefit with lapatinib in combination with trastuzumab for patients with human epidermal growth factor receptor 2-positive metastatic breast cancer: final results from the EGF104900 Study
    • Blackwell KL, Burstein HJ, Storniolo AM, Rugo HS, Sledge G, Aktan G, Ellis C, Florance A, Vukelja S, Bischoff J, Baselga J, O'Shaughnessy J (2012) Overall survival benefit with lapatinib in combination with trastuzumab for patients with human epidermal growth factor receptor 2-positive metastatic breast cancer: final results from the EGF104900 Study. J Clin Oncol. 30 (21):2585–2592.
    • (2012) J Clin Oncol , vol.30 , Issue.21 , pp. 2585-2592
    • Blackwell, K.L.1    Burstein, H.J.2    Storniolo, A.M.3    Rugo, H.S.4    Sledge, G.5    Aktan, G.6    Ellis, C.7    Florance, A.8    Vukelja, S.9    Bischoff, J.10    Baselga, J.11    O'Shaughnessy, J.12


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