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Volumn 88, Issue 6, 2015, Pages 1217-1218

Reviving the promise of transcription factor Nrf2-based therapeutics for kidney diseases

Author keywords

[No Author keywords available]

Indexed keywords

BARDOXOLONE METHYL; CHALCONE DERIVATIVE; GLUTATHIONE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; LYCOPENE; OLEANOLIC ACID; PLACEBO; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RESVERATROL; SULFORAPHANE; TRANSCRIPTION FACTOR NRF2;

EID: 84949895799     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2015.328     Document Type: Article
Times cited : (25)

References (11)
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  • 2
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    • Systemic inflammation and oxidative stress in hemodialysis patients are associated with down-regulation of Nrf2
    • Pedruzzi LM, Cardozo LF, Daleprane JB et al. Systemic inflammation and oxidative stress in hemodialysis patients are associated with down-regulation of Nrf2. J Nephrol 2015; 28: 495-501
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  • 3
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    • Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemiareperfusion injury
    • Leonard MO, Kieran NE, Howell K et al. Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemiareperfusion injury. FASEB J 2006; 20: 2624-2626
    • (2006) FASEB J , vol.20 , pp. 2624-2626
    • Leonard, M.O.1    Kieran, N.E.2    Howell, K.3
  • 4
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    • The Nrf2 triterpenoid activator, CDDO-imidazolide, protects kidneys from ischemia-reperfusion injury in mice
    • Liu M, Reddy NM, Higbee EM et al. The Nrf2 triterpenoid activator, CDDO-imidazolide, protects kidneys from ischemia-reperfusion injury in mice. Kidney Int 2014; 85: 134-141
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    • Liu, M.1    Reddy, N.M.2    Higbee, E.M.3
  • 5
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    • Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPAR, and HO-1
    • Wu QQ, Wang Y, Senitko M et al. Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPAR, and HO-1. Am J Physiol Renal Physiol 2011; 300: F1180-F1192
    • (2011) Am J Physiol Renal Physiol , vol.300 , pp. F1180-F1192
    • Wu, Q.Q.1    Wang, Y.2    Senitko, M.3
  • 6
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    • Bardoxolone methyl and kidney function in CKD with type 2 diabetes
    • Pergola PE, Raskin P, Toto RD et al. Bardoxolone methyl and kidney function in CKD with type 2 diabetes. N Engl J Med 2011; 365: 327-336
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    • Pergola, P.E.1    Raskin, P.2    Toto, R.D.3
  • 7
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    • Mechanisms contributing to adverse cardiovascular events in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl
    • Chin MP, Reisman SA, Bakris GL et al. Mechanisms contributing to adverse cardiovascular events in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl. Am J Nephrol 2014; 39: 499-508
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  • 8
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    • Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney
    • Shelton LM, Lister A, Walsh J et al. Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney. Kidney Int 2015; 88: 1261-1273
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    • Shelton, L.M.1    Lister, A.2    Walsh, J.3
  • 9
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    • T lymphocyte-specific activation of Nrf2 protects from AKI
    • (e-pub ahead of print)
    • Noel S, Martina MN, Bandapalle S et al. T lymphocyte-specific activation of Nrf2 protects from AKI. J Am Soc Nephrol 2015, (e-pub ahead of print)
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  • 10
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    • Noel S, Arend LJ, Bandapalle S et al. Deletion of kelch-like ECH associated protein 1 (Keap1) in kidney epithelial cells causes hydronephrosis in mice. J Am Soc Nephrol 2014; 25: 538A
    • (2014) J Am Soc Nephrol , vol.25 , pp. 538A
    • Noel, S.1    Arend, L.J.2    Bandapalle, S.3
  • 11
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.