Inhibition of heat-shock protein 90 sensitizes liver cancer stem-like cells to magnetic hyperthermia and enhances anti-tumor effect on hepatocellular carcinoma-burdened nude mice

International Journal of Nanomedicine

Volumn 10, Issue , 2015, Pages 7345-7358

  Yang, Rui ^a   Tang, Qiusha ^a   Miao, Fengqin ^a   An, Yanli ^b   Li, Mengfei ^a   Han, Yong ^a   Wang, Xihui ^a   Wang, Juan ^c   Liu, Peidang ^a   Chen, Rong ^b  

^a MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

^b AFFILIATED ZHONGDA HOSPITAL OF SOUTHEAST UNIVERSITY   (China)

^c The Third People s Hospital of Nantong   (China)

Author keywords

17 AAG; CD90+ LCSCs; Magnetic hyperthermia; Thermoresistance

Indexed keywords

CASPASE 3; DOXORUBICIN; FLUOROURACIL; HEAT SHOCK PROTEIN 90; LIPOSOME; MACROGOL 2000; MAGNETOLIPOSOME; NANOCARRIER; OXALIPLATIN; TANESPIMYCIN; THY 1 ANTIGEN; UNCLASSIFIED DRUG; BENZOQUINONE DERIVATIVE; MACROCYCLIC LACTAM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER RESISTANCE; CANCER STEM CELL; CELL ISOLATION; CHEMOSENSITIZATION; CONTROLLED STUDY; DOWN REGULATION; DRUG DETERMINATION; DRUG EFFECT; DRUG MECHANISM; DRUG RELEASE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENCAPSULATION; FEMALE; HEAT TOLERANCE; HUMAN; HUMAN CELL; HYPERTHERMIC THERAPY; IC50; IN VITRO STUDY; IN VIVO STUDY; LIVER CANCER CELL LINE; LIVER CELL CARCINOMA; MAGNETIC HYPERTHERMIA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TUMOR VOLUME; ANIMAL; ANTAGONISTS AND INHIBITORS; CARCINOMA, HEPATOCELLULAR; DRUG EFFECTS; LIVER NEOPLASMS; MAGNETISM; NUDE MOUSE; PATHOLOGY; THERMOTHERAPY; TUMOR CELL LINE;

ANIMALS; BENZOQUINONES; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; FEMALE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; HYPERTHERMIA, INDUCED; LACTAMS, MACROCYCLIC; LIVER NEOPLASMS; MAGNETIC PHENOMENA; MICE; MICE, NUDE; NEOPLASTIC STEM CELLS;

EID: 84949800760     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S93758     Document Type: Article

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