메뉴 건너뛰기




Volumn 6, Issue NOV, 2015, Pages

Cerebrospinal fluid Aβ40 improves the interpretation of Aβ42 concentration for diagnosing Alzheimer's disease

Author keywords

Alzheimer; A 40; A 42; Cerebrospinal fluid; Dementia

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42];

EID: 84949746920     PISSN: None     EISSN: 16642295     Source Type: Journal    
DOI: 10.3389/fneur.2015.00247     Document Type: Article
Times cited : (49)

References (49)
  • 1
    • 79956142378 scopus 로고    scopus 로고
    • The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR Jr, Kawas CH, et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 7(3):263-9. doi: 10.1016/j.jalz.2011.03.005.
    • (2011) Alzheimers Dement , vol.7 , Issue.3 , pp. 263-269
    • McKhann, G.M.1    Knopman, D.S.2    Chertkow, H.3    Hyman, B.T.4    Jack, C.R.5    Kawas, C.H.6
  • 2
    • 84900988440 scopus 로고    scopus 로고
    • Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria
    • Dubois B, Feldman HH, Jacova C, Hampel H, Molinuevo JL, Blennow K, et al. Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria. Lancet Neurol (2014) 13(6):614-29. doi:10.1016/S1474-4422(14)70090-0.
    • (2014) Lancet Neurol , vol.13 , Issue.6 , pp. 614-629
    • Dubois, B.1    Feldman, H.H.2    Jacova, C.3    Hampel, H.4    Molinuevo, J.L.5    Blennow, K.6
  • 3
    • 77956629252 scopus 로고    scopus 로고
    • EFNS guidelines for the diagnosis and management of Alzheimer's disease
    • Hort J, O'Brien JT, Gainotti G, Pirttila T, Popescu BO, Rektorova I, et al. EFNS guidelines for the diagnosis and management of Alzheimer's disease. Eur J Neurol (2010) 17(10):1236-48. doi:10.1111/j.1468-1331.2010.03040.x.
    • (2010) Eur J Neurol , vol.17 , Issue.10 , pp. 1236-1248
    • Hort, J.1    O'Brien, J.T.2    Gainotti, G.3    Pirttila, T.4    Popescu, B.O.5    Rektorova, I.6
  • 5
    • 79956084514 scopus 로고    scopus 로고
    • The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • Albert MS, DeKosky ST, Dickson D, Dubois B, Feldman HH, Fox NC, et al. The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 7(3):270-9. doi:10.1016/j.jalz.2011.03.008.
    • (2011) Alzheimers Dement , vol.7 , Issue.3 , pp. 270-279
    • Albert, M.S.1    DeKosky, S.T.2    Dickson, D.3    Dubois, B.4    Feldman, H.H.5    Fox, N.C.6
  • 7
    • 84908234391 scopus 로고    scopus 로고
    • Impact of harmonization of collection tubes on Alzheimer's disease diagnosis
    • Lehmann S, Schraen S, Quadrio I, Paquet C, Bombois S, Delaby C, et al. Impact of harmonization of collection tubes on Alzheimer's disease diagnosis. Alzheimers Dement (2013) 10(5 Suppl):S390-4. doi:10.1016/j.jalz.2013.06.008.
    • (2013) Alzheimers Dement , vol.10 , Issue.5 , pp. S390-S394
    • Lehmann, S.1    Schraen, S.2    Quadrio, I.3    Paquet, C.4    Bombois, S.5    Delaby, C.6
  • 8
    • 84927178751 scopus 로고    scopus 로고
    • The clinical use of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: a consensus paper from the Alzheimer's Biomarkers Standardization Initiative
    • Molinuevo JL, Blennow K, Dubois B, Engelborghs S, Lewczuk P, Perret-Liaudet A, et al. The clinical use of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: a consensus paper from the Alzheimer's Biomarkers Standardization Initiative. Alzheimers Dement (2014) 10(6):808-17. doi:10.1016/j.jalz.2014.03.003.
    • (2014) Alzheimers Dement , vol.10 , Issue.6 , pp. 808-817
    • Molinuevo, J.L.1    Blennow, K.2    Dubois, B.3    Engelborghs, S.4    Lewczuk, P.5    Perret-Liaudet, A.6
  • 9
    • 84923339368 scopus 로고    scopus 로고
    • Cerebrospinal fluid beta-amyloid1-42 levels in the differential diagnosis of Alzheimer's disease-systematic review and meta-analysis
    • Mo JA, Lim JH, Sul AR, Lee M, Youn YC, Kim HJ. Cerebrospinal fluid beta-amyloid1-42 levels in the differential diagnosis of Alzheimer's disease-systematic review and meta-analysis. PLoS One (2015) 10(2):e0116802. doi:10.1371/journal.pone.0116802.
    • (2015) PLoS One , vol.10 , Issue.2
    • Mo, J.A.1    Lim, J.H.2    Sul, A.R.3    Lee, M.4    Youn, Y.C.5    Kim, H.J.6
  • 10
    • 84949827682 scopus 로고    scopus 로고
    • Benchmarking biomarker-based criteria for Alzheimer's disease: data from the Swedish Dementia Registry, SveDem
    • Rosen C, Farahmand B, Skillback T, Nagga K, Mattsson N, Kilander L, et al. Benchmarking biomarker-based criteria for Alzheimer's disease: data from the Swedish Dementia Registry, SveDem. Alzheimers Dement (2015). doi:10.1016/j.jalz.2015.04.007.
    • (2015) Alzheimers Dement
    • Rosen, C.1    Farahmand, B.2    Skillback, T.3    Nagga, K.4    Mattsson, N.5    Kilander, L.6
  • 11
    • 34247581358 scopus 로고    scopus 로고
    • Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low-and high-CSF A beta 40 load
    • Wiltfang J, Esselmann H, Bibl M, Hull M, Hampel H, Kessler H, et al. Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low-and high-CSF A beta 40 load. J Neurochem (2007) 101(4):1053-9. doi:10.1111/j.1471-4159.2006.04404.x.
    • (2007) J Neurochem , vol.101 , Issue.4 , pp. 1053-1059
    • Wiltfang, J.1    Esselmann, H.2    Bibl, M.3    Hull, M.4    Hampel, H.5    Kessler, H.6
  • 12
    • 18444393054 scopus 로고    scopus 로고
    • Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation
    • Wiltfang J, Esselmann H, Bibl M, Smirnov A, Otto M, Paul S, et al. Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation. J Neurochem (2002) 81(3):481-96. doi:10.1046/j.1471-4159.2002.00818.x.
    • (2002) J Neurochem , vol.81 , Issue.3 , pp. 481-496
    • Wiltfang, J.1    Esselmann, H.2    Bibl, M.3    Smirnov, A.4    Otto, M.5    Paul, S.6
  • 13
    • 78349287910 scopus 로고    scopus 로고
    • The cerebrospinal fluid amyloid beta42/40 ratio in the differentiation of Alzheimer's disease from non-Alzheimer's dementia
    • Spies PE, Slats D, Sjogren JM, Kremer BP, Verhey FR, Rikkert MG, et al. The cerebrospinal fluid amyloid beta42/40 ratio in the differentiation of Alzheimer's disease from non-Alzheimer's dementia. Curr Alzheimer Res (2010) 7(5):470-6. doi:10.2174/156720510791383796.
    • (2010) Curr Alzheimer Res , vol.7 , Issue.5 , pp. 470-476
    • Spies, P.E.1    Slats, D.2    Sjogren, J.M.3    Kremer, B.P.4    Verhey, F.R.5    Rikkert, M.G.6
  • 14
    • 75549090428 scopus 로고    scopus 로고
    • Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study
    • Lewczuk P, Kamrowski-Kruck H, Peters O, Heuser I, Jessen F, Popp J, et al. Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study. Mol Psychiatry (2010) 15(2):138-45. doi:10.1038/mp.2008.84.
    • (2010) Mol Psychiatry , vol.15 , Issue.2 , pp. 138-145
    • Lewczuk, P.1    Kamrowski-Kruck, H.2    Peters, O.3    Heuser, I.4    Jessen, F.5    Popp, J.6
  • 15
    • 33645775230 scopus 로고    scopus 로고
    • Determination of beta-amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry
    • Portelius E, Westman-Brinkmalm A, Zetterberg H, Blennow K. Determination of beta-amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry. J Proteome Res (2006) 5(4):1010-6. doi:10.1021/pr050475v.
    • (2006) J Proteome Res , vol.5 , Issue.4 , pp. 1010-1016
    • Portelius, E.1    Westman-Brinkmalm, A.2    Zetterberg, H.3    Blennow, K.4
  • 16
    • 40949119905 scopus 로고    scopus 로고
    • Neurochemical approaches of cerebrospinal fluid diagnostics in neurodegenerative diseases
    • Otto M, Lewczuk P, Wiltfang J. Neurochemical approaches of cerebrospinal fluid diagnostics in neurodegenerative diseases. Methods (2008) 44(4):289-98. doi:10.1016/j.ymeth.2007.06.012.
    • (2008) Methods , vol.44 , Issue.4 , pp. 289-298
    • Otto, M.1    Lewczuk, P.2    Wiltfang, J.3
  • 17
    • 0028915895 scopus 로고
    • Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43)
    • Gravina SA, Ho L, Eckman CB, Long KE, Otvos L Jr, Younkin LH, et al. Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43). J Biol Chem (1995) 270(13):7013-6.
    • (1995) J Biol Chem , vol.270 , Issue.13 , pp. 7013-7016
    • Gravina, S.A.1    Ho, L.2    Eckman, C.B.3    Long, K.E.4    Otvos, L.5    Younkin, L.H.6
  • 18
    • 41549142204 scopus 로고    scopus 로고
    • Neurochemical dementia diagnostics: state of the art and research perspectives
    • Lewczuk P, Wiltfang J. Neurochemical dementia diagnostics: state of the art and research perspectives. Proteomics (2008) 8(6):1292-301. doi:10.1002/pmic.200700703.
    • (2008) Proteomics , vol.8 , Issue.6 , pp. 1292-1301
    • Lewczuk, P.1    Wiltfang, J.2
  • 19
    • 0037225726 scopus 로고    scopus 로고
    • Brain-specific proteins in cerebrospinal fluid for the diagnosis of neurodegenerative diseases
    • Verbeek MM, De Jong D, Kremer HP. Brain-specific proteins in cerebrospinal fluid for the diagnosis of neurodegenerative diseases. Ann Clin Biochem (2003) 40(Pt 1):25-40. doi:10.1258/000456303321016141.
    • (2003) Ann Clin Biochem , vol.40 , pp. 25-40
    • Verbeek, M.M.1    De Jong, D.2    Kremer, H.P.3
  • 20
    • 34247384609 scopus 로고    scopus 로고
    • Prediction of Alzheimer's disease using the CSF Abeta42/Abeta40 ratio in patients with mild cognitive impairment
    • Hansson O, Zetterberg H, Buchhave P, Andreasson U, Londos E, Minthon L, et al. Prediction of Alzheimer's disease using the CSF Abeta42/Abeta40 ratio in patients with mild cognitive impairment. Dement Geriatr Cogn Disord (2007) 23(5):316-20. doi:10.1159/000100926.
    • (2007) Dement Geriatr Cogn Disord , vol.23 , Issue.5 , pp. 316-320
    • Hansson, O.1    Zetterberg, H.2    Buchhave, P.3    Andreasson, U.4    Londos, E.5    Minthon, L.6
  • 21
    • 0033975837 scopus 로고    scopus 로고
    • Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease
    • Mehta PD, Pirttila T, Mehta SP, Sersen EA, Aisen PS, Wisniewski HM. Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease. Arch Neurol (2000) 57(1):100-5. doi:10.1001/archneur.57.1.100.
    • (2000) Arch Neurol , vol.57 , Issue.1 , pp. 100-105
    • Mehta, P.D.1    Pirttila, T.2    Mehta, S.P.3    Sersen, E.A.4    Aisen, P.S.5    Wisniewski, H.M.6
  • 22
    • 0032581113 scopus 로고    scopus 로고
    • Combination assay of CSF tau, A beta 1-40 and A beta 1-42(43) as a biochemical marker of Alzheimer's disease
    • Shoji M, Matsubara E, Kanai M, Watanabe M, Nakamura T, Tomidokoro Y, et al. Combination assay of CSF tau, A beta 1-40 and A beta 1-42(43) as a biochemical marker of Alzheimer's disease. J Neurol Sci (1998) 158(2):134-40. doi:10.1016/S0022-510X(98)00122-1.
    • (1998) J Neurol Sci , vol.158 , Issue.2 , pp. 134-140
    • Shoji, M.1    Matsubara, E.2    Kanai, M.3    Watanabe, M.4    Nakamura, T.5    Tomidokoro, Y.6
  • 23
    • 14444269228 scopus 로고    scopus 로고
    • Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: a study in Japan
    • Kanai M, Matsubara E, Isoe K, Urakami K, Nakashima K, Arai H, et al. Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: a study in Japan. Ann Neurol (1998) 44(1):17-26. doi:10.1002/ana.410440108.
    • (1998) Ann Neurol , vol.44 , Issue.1 , pp. 17-26
    • Kanai, M.1    Matsubara, E.2    Isoe, K.3    Urakami, K.4    Nakashima, K.5    Arai, H.6
  • 24
    • 0034027642 scopus 로고    scopus 로고
    • Age-dependent change in the levels of Abeta40 and Abeta42 in cerebrospinal fluid from control subjects, and a decrease in the ratio of Abeta42 to Abeta40 level in cerebrospinal fluid from Alzheimer's disease patients
    • Fukuyama R, Mizuno T, Mori S, Nakajima K, Fushiki S, Yanagisawa K. Age-dependent change in the levels of Abeta40 and Abeta42 in cerebrospinal fluid from control subjects, and a decrease in the ratio of Abeta42 to Abeta40 level in cerebrospinal fluid from Alzheimer's disease patients. Eur Neurol (2000) 43(3):155-60. doi:10.1159/000008157.
    • (2000) Eur Neurol , vol.43 , Issue.3 , pp. 155-160
    • Fukuyama, R.1    Mizuno, T.2    Mori, S.3    Nakajima, K.4    Fushiki, S.5    Yanagisawa, K.6
  • 26
    • 84881438514 scopus 로고    scopus 로고
    • Cerebrospinal fluid Abeta1-40 improves differential dementia diagnosis in patients with intermediate P-tau181P levels
    • Slaets S, Le Bastard N, Martin JJ, Sleegers K, Van Broeckhoven C, De Deyn PP, et al. Cerebrospinal fluid Abeta1-40 improves differential dementia diagnosis in patients with intermediate P-tau181P levels. J Alzheimers Dis (2013) 36(4):759-67. doi:10.3233/JAD-130107.
    • (2013) J Alzheimers Dis , vol.36 , Issue.4 , pp. 759-767
    • Slaets, S.1    Le Bastard, N.2    Martin, J.J.3    Sleegers, K.4    Van Broeckhoven, C.5    De Deyn, P.P.6
  • 27
    • 84920577032 scopus 로고    scopus 로고
    • Additional use of Abeta(4)(2)/Abeta(4)(0) ratio with cerebrospinal fluid biomarkers P-tau and Abeta(4)(2) increases the level of evidence of Alzheimer's disease pathophysiological process in routine practice
    • Sauvee M, DidierLaurent G, Latarche C, Escanye MC, Olivier JL, Malaplate-Armand C. Additional use of Abeta(4)(2)/Abeta(4)(0) ratio with cerebrospinal fluid biomarkers P-tau and Abeta(4)(2) increases the level of evidence of Alzheimer's disease pathophysiological process in routine practice. J Alzheimers Dis (2014) 41(2):377-86. doi:10.3233/JAD-131838.
    • (2014) J Alzheimers Dis , vol.41 , Issue.2 , pp. 377-386
    • Sauvee, M.1    DidierLaurent, G.2    Latarche, C.3    Escanye, M.C.4    Olivier, J.L.5    Malaplate-Armand, C.6
  • 28
    • 84930205601 scopus 로고    scopus 로고
    • Cerebrospinal fluid amyloid-beta 42/40 ratio in clinical setting of memory centers: a multicentric study
    • Dumurgier J, Schraen S, Gabelle A, Vercruysse O, Bombois S, Laplanche JL, et al. Cerebrospinal fluid amyloid-beta 42/40 ratio in clinical setting of memory centers: a multicentric study. Alzheimers Res Ther (2015) 7(1):30. doi:10.1186/s13195-015-0114-5.
    • (2015) Alzheimers Res Ther , vol.7 , Issue.1 , pp. 30
    • Dumurgier, J.1    Schraen, S.2    Gabelle, A.3    Vercruysse, O.4    Bombois, S.5    Laplanche, J.L.6
  • 30
    • 33144489150 scopus 로고    scopus 로고
    • Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium
    • McKeith IG, Dickson DW, Lowe J, Emre M, O'Brien JT, Feldman H, et al. Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology (2005) 65(12):1863-72. doi:10.1212/01.wnl.0000187889.17253.b1.
    • (2005) Neurology , vol.65 , Issue.12 , pp. 1863-1872
    • McKeith, I.G.1    Dickson, D.W.2    Lowe, J.3    Emre, M.4    O'Brien, J.T.5    Feldman, H.6
  • 31
    • 80052938441 scopus 로고    scopus 로고
    • Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
    • Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Neuhaus J, et al. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain (2011) 134(Pt 9):2456-77. doi:10.1093/brain/awr179.
    • (2011) Brain , vol.134 , pp. 2456-2477
    • Rascovsky, K.1    Hodges, J.R.2    Knopman, D.3    Mendez, M.F.4    Kramer, J.H.5    Neuhaus, J.6
  • 32
    • 84856008210 scopus 로고    scopus 로고
    • Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: a consensus paper from the Alzheimer's Biomarkers Standardization Initiative
    • Vanderstichele H, Bibl M, Engelborghs S, Le Bastard N, Lewczuk P, Molinuevo JL, et al. Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: a consensus paper from the Alzheimer's Biomarkers Standardization Initiative. Alzheimers Dement (2012) 8(1):65-73. doi:10.1016/j.jalz.2011.07.004.
    • (2012) Alzheimers Dement , vol.8 , Issue.1 , pp. 65-73
    • Vanderstichele, H.1    Bibl, M.2    Engelborghs, S.3    Le Bastard, N.4    Lewczuk, P.5    Molinuevo, J.L.6
  • 33
    • 84865477339 scopus 로고    scopus 로고
    • Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update
    • del Campo M, Mollenhauer B, Bertolotto A, Engelborghs S, Hampel H, Simonsen AH, et al. Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update. Biomark Med (2012) 6(4):419-30. doi:10.2217/bmm.12.46.
    • (2012) Biomark Med , vol.6 , Issue.4 , pp. 419-430
    • del Campo, M.1    Mollenhauer, B.2    Bertolotto, A.3    Engelborghs, S.4    Hampel, H.5    Simonsen, A.H.6
  • 34
    • 84876909712 scopus 로고    scopus 로고
    • CSF biomarker variability in the Alzheimer's Association quality control program
    • Mattsson N, Andreasson U, Persson S, Carrillo MC, Collins S, Chalbot S, et al. CSF biomarker variability in the Alzheimer's Association quality control program. Alzheimers Dement (2013) 9(3):251-61. doi:10.1016/j.jalz.2013.01.010.
    • (2013) Alzheimers Dement , vol.9 , Issue.3 , pp. 251-261
    • Mattsson, N.1    Andreasson, U.2    Persson, S.3    Carrillo, M.C.4    Collins, S.5    Chalbot, S.6
  • 35
    • 0018079655 scopus 로고
    • Basic principles of ROC analysis
    • Metz CE. Basic principles of ROC analysis. Semin Nucl Med (1978) 8(4):283-98. doi:10.1016/S0001-2998(78)80014-2.
    • (1978) Semin Nucl Med , vol.8 , Issue.4 , pp. 283-298
    • Metz, C.E.1
  • 36
    • 84908700565 scopus 로고    scopus 로고
    • Amyloid-beta 42/40 cerebrospinal fluid concentration ratio in the diagnostics of Alzheimer's disease: validation of two novel assays
    • Lewczuk P, Lelental N, Spitzer P, Maler JM, Kornhuber J. Amyloid-beta 42/40 cerebrospinal fluid concentration ratio in the diagnostics of Alzheimer's disease: validation of two novel assays. J Alzheimers Dis (2015) 43(1):183-91. doi:10.3233/JAD-140771.
    • (2015) J Alzheimers Dis , vol.43 , Issue.1 , pp. 183-191
    • Lewczuk, P.1    Lelental, N.2    Spitzer, P.3    Maler, J.M.4    Kornhuber, J.5
  • 37
    • 31844443892 scopus 로고    scopus 로고
    • Effect of sample collection tubes on cerebrospinal fluid concentrations of tau proteins and amyloid beta peptides
    • Lewczuk P, Beck G, Esselmann H, Bruckmoser R, Zimmermann R, Fiszer M, et al. Effect of sample collection tubes on cerebrospinal fluid concentrations of tau proteins and amyloid beta peptides. Clin Chem (2006) 52(2):332-4. doi:10.1373/clinchem.2005.058776.
    • (2006) Clin Chem , vol.52 , Issue.2 , pp. 332-334
    • Lewczuk, P.1    Beck, G.2    Esselmann, H.3    Bruckmoser, R.4    Zimmermann, R.5    Fiszer, M.6
  • 38
    • 84940435280 scopus 로고    scopus 로고
    • Pre-analytical and analytical factors influencing Alzheimer's disease cerebrospinal fluid biomarkers variability
    • Fourier A, Portelius E, Zetterberg H, Blennow K, Quadrio I, Perret-Liaudet A. Pre-analytical and analytical factors influencing Alzheimer's disease cerebrospinal fluid biomarkers variability. Clin Chim Acta (2015) 449:9-15. doi:10.1016/j.cca.2015.05.024.
    • (2015) Clin Chim Acta , vol.449 , pp. 9-15
    • Fourier, A.1    Portelius, E.2    Zetterberg, H.3    Blennow, K.4    Quadrio, I.5    Perret-Liaudet, A.6
  • 39
    • 20944439059 scopus 로고    scopus 로고
    • Cerebrospinal fluid profile in frontotemporal dementia and Alzheimer's disease
    • Grossman M, Farmer J, Leight S, Work M, Moore P, Van Deerlin V, et al. Cerebrospinal fluid profile in frontotemporal dementia and Alzheimer's disease. Ann Neurol (2005) 57(5):721-9. doi:10.1002/ana.20477.
    • (2005) Ann Neurol , vol.57 , Issue.5 , pp. 721-729
    • Grossman, M.1    Farmer, J.2    Leight, S.3    Work, M.4    Moore, P.5    Van Deerlin, V.6
  • 40
    • 67349214609 scopus 로고    scopus 로고
    • Improved discrimination of autopsy-confirmed Alzheimer's disease (AD) from non-AD dementias using CSF P-tau(181P)
    • Koopman K, Le Bastard N, Martin JJ, Nagels G, De Deyn PP, Engelborghs S. Improved discrimination of autopsy-confirmed Alzheimer's disease (AD) from non-AD dementias using CSF P-tau(181P). Neurochem Int (2009) 55(4):214-8. doi:10.1016/j.neuint.2009.02.017.
    • (2009) Neurochem Int , vol.55 , Issue.4 , pp. 214-218
    • Koopman, K.1    Le Bastard, N.2    Martin, J.J.3    Nagels, G.4    De Deyn, P.P.5    Engelborghs, S.6
  • 41
    • 84856617005 scopus 로고    scopus 로고
    • Cerebrospinal fluid markers for differential dementia diagnosis in a large memory clinic cohort
    • Schoonenboom NS, Reesink FE, Verwey NA, Kester MI, Teunissen CE, van de Ven PM, et al. Cerebrospinal fluid markers for differential dementia diagnosis in a large memory clinic cohort. Neurology (2012) 78(1):47-54. doi:10.1212/WNL.0b013e31823ed0f0.
    • (2012) Neurology , vol.78 , Issue.1 , pp. 47-54
    • Schoonenboom, N.S.1    Reesink, F.E.2    Verwey, N.A.3    Kester, M.I.4    Teunissen, C.E.5    van de Ven, P.M.6
  • 42
    • 79951801800 scopus 로고    scopus 로고
    • Cerebrospinal fluid biomarkers in the differential diagnosis of Alzheimer's disease from other cortical dementias
    • de Souza LC, Lamari F, Belliard S, Jardel C, Houillier C, De Paz R, et al. Cerebrospinal fluid biomarkers in the differential diagnosis of Alzheimer's disease from other cortical dementias. J Neurol Neurosurg Psychiatry (2011) 82(3):240-6. doi:10.1136/jnnp.2010.207183.
    • (2011) J Neurol Neurosurg Psychiatry , vol.82 , Issue.3 , pp. 240-246
    • de Souza, L.C.1    Lamari, F.2    Belliard, S.3    Jardel, C.4    Houillier, C.5    De Paz, R.6
  • 43
    • 84862753578 scopus 로고    scopus 로고
    • CSF biomarkers cutoffs: the importance of coincident neuropathological diseases
    • Toledo JB, Brettschneider J, Grossman M, Arnold SE, Hu WT, Xie SX, et al. CSF biomarkers cutoffs: the importance of coincident neuropathological diseases. Acta Neuropathol (2012) 124(1):23-35. doi:10.1007/s00401-012-0983-7.
    • (2012) Acta Neuropathol , vol.124 , Issue.1 , pp. 23-35
    • Toledo, J.B.1    Brettschneider, J.2    Grossman, M.3    Arnold, S.E.4    Hu, W.T.5    Xie, S.X.6
  • 44
    • 84883457258 scopus 로고    scopus 로고
    • Non-Alzheimer neurodegenerative pathologies and their combinations are more frequent than commonly believed in the elderly brain: a community-based autopsy series
    • Kovacs GG, Milenkovic I, Wohrer A, Hoftberger R, Gelpi E, Haberler C, et al. Non-Alzheimer neurodegenerative pathologies and their combinations are more frequent than commonly believed in the elderly brain: a community-based autopsy series. Acta Neuropathol (2013) 126(3):365-84. doi:10.1007/s00401-013-1157-y.
    • (2013) Acta Neuropathol , vol.126 , Issue.3 , pp. 365-384
    • Kovacs, G.G.1    Milenkovic, I.2    Wohrer, A.3    Hoftberger, R.4    Gelpi, E.5    Haberler, C.6
  • 45
    • 84927938618 scopus 로고    scopus 로고
    • Prevalence of mixed pathologies in the aging brain
    • Rahimi J, Kovacs GG. Prevalence of mixed pathologies in the aging brain. Alzheimers Res Ther (2014) 6(9):82. doi:10.1186/s13195-014-0082-1.
    • (2014) Alzheimers Res Ther , vol.6 , Issue.9 , pp. 82
    • Rahimi, J.1    Kovacs, G.G.2
  • 46
    • 84925553630 scopus 로고    scopus 로고
    • Alzheimer CSF biomarkers may be misleading in normal-pressure hydrocephalus
    • Graff-Radford NR. Alzheimer CSF biomarkers may be misleading in normal-pressure hydrocephalus. Neurology (2014) 83(17):1573-5. doi:10.1212/WNL.0000000000000916.
    • (2014) Neurology , vol.83 , Issue.17 , pp. 1573-1575
    • Graff-Radford, N.R.1
  • 47
    • 84876261561 scopus 로고    scopus 로고
    • Idiopathic normal-pressure hydrocephalus: pathophysiology and diagnosis by CSF biomarkers
    • Jeppsson A, Zetterberg H, Blennow K, Wikkelso C. Idiopathic normal-pressure hydrocephalus: pathophysiology and diagnosis by CSF biomarkers. Neurology (2013) 80(15):1385-92. doi:10.1212/WNL.0b013e31828c2fda.
    • (2013) Neurology , vol.80 , Issue.15 , pp. 1385-1392
    • Jeppsson, A.1    Zetterberg, H.2    Blennow, K.3    Wikkelso, C.4
  • 48
    • 77957267776 scopus 로고    scopus 로고
    • Correlations between soluble alpha/beta forms of amyloid precursor protein and Abeta38, 40 and 42 in human cerebrospinal fluid
    • Gabelle A, Roche S, Geny C, Bennys K, Labauge P, Tholance Y, et al. Correlations between soluble alpha/beta forms of amyloid precursor protein and Abeta38, 40 and 42 in human cerebrospinal fluid. Brain Res (2010) 1357:175-83. doi:10.1016/j.brainres.2010.08.022.
    • (2010) Brain Res , vol.1357 , pp. 175-183
    • Gabelle, A.1    Roche, S.2    Geny, C.3    Bennys, K.4    Labauge, P.5    Tholance, Y.6
  • 49
    • 80053510055 scopus 로고    scopus 로고
    • Decreased sAbetaPPbeta, Abeta38, and Abeta40 cerebrospinal fluid levels in frontotemporal dementia
    • Gabelle A, Roche S, Geny C, Bennys K, Labauge P, Tholance Y, et al. Decreased sAbetaPPbeta, Abeta38, and Abeta40 cerebrospinal fluid levels in frontotemporal dementia. J Alzheimers Dis (2011) 26(3):553-63. doi:10.3233/JAD-2011-110515.
    • (2011) J Alzheimers Dis , vol.26 , Issue.3 , pp. 553-563
    • Gabelle, A.1    Roche, S.2    Geny, C.3    Bennys, K.4    Labauge, P.5    Tholance, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.